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Volumn , Issue , 2013, Pages 23-45

Demyelination and Remyelination in Multiple Sclerosis

Author keywords

Multiple Sclerosis; Multiple Sclerosis Lesion; Multiple Sclerosis Patient; Myelin Sheath; Progressive Multifocal Leukoencephalopathy

Indexed keywords


EID: 84888418692     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-4614-2218-1_2     Document Type: Chapter
Times cited : (10)

References (122)
  • 1
    • 0016607803 scopus 로고
    • Binding of normal human IgG to myelin sheaths, glia and neurons
    • Aarli JA, Aparicio SR, Lumsden CE, Tonder O (1975) Binding of normal human IgG to myelin sheaths, glia and neurons. Immunology 28:171–185
    • (1975) Immunology , vol.28 , pp. 171-185
    • Aarli, J.A.1    Aparicio, S.R.2    Lumsden, C.E.3    Tonder, O.4
  • 2
    • 33947547648 scopus 로고    scopus 로고
    • Extensive cortical remyelination in patients with chronic multiple sclerosis
    • Albert M, Antel J, Bruck W, Stadelmann C (2007) Extensive cortical remyelination in patients with chronic multiple sclerosis. Brain Pathol 17:129–138
    • (2007) Brain Pathol , vol.17 , pp. 129-138
    • Albert, M.1    Antel, J.2    Bruck, W.3    Stadelmann, C.4
  • 6
    • 0025850757 scopus 로고
    • The longstanding MS lesion. A quantitative MRI and electron microscopic study
    • Barnes D, Munro PM, Youl BD, Prineas JW, McDonald WI (1991) The longstanding MS lesion. A quantitative MRI and electron microscopic study. Brain 114(Pt 3):1271–1280
    • (1991) Brain , vol.114 , Issue.3 , pp. 1271-1280
    • Barnes, D.1    Munro, P.M.2    Youl, B.D.3    Prineas, J.W.4    McDonald, W.I.5
  • 7
    • 1642281535 scopus 로고    scopus 로고
    • Relapsing and remitting multiple sclerosis: Pathology of the newly forming lesion
    • Barnett MH, Prineas JW (2004) Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion. Ann Neurol 55:458–468
    • (2004) Ann Neurol , vol.55 , pp. 458-468
    • Barnett, M.H.1    Prineas, J.W.2
  • 8
    • 0034026912 scopus 로고    scopus 로고
    • Acute axonal injury in multiple sclerosis. Correlation with demyelination and inflammation
    • Bitsch A, Schuchardt J, Bunkowski S, Kuhlmann T, Bruck W (2000) Acute axonal injury in multiple sclerosis. Correlation with demyelination and inflammation. Brain 123(Pt 6):1174–1183
    • (2000) Brain , vol.123 , Issue.6 , pp. 1174-1183
    • Bitsch, A.1    Schuchardt, J.2    Bunkowski, S.3    Kuhlmann, T.4    Bruck, W.5
  • 10
    • 0028231281 scopus 로고
    • Detection of MHC class II-antigens on macrophages and microglia, but not on astrocytes and endothelia in active multiple sclerosis lesions
    • Bo L, Mork S, Kong PA, Nyland H, Pardo CA, Trapp BD (1994) Detection of MHC class II-antigens on macrophages and microglia, but not on astrocytes and endothelia in active multiple sclerosis lesions. J Neuroimmunol 51:135–146
    • (1994) J Neuroimmunol , vol.51 , pp. 135-146
    • Bo, L.1    Mork, S.2    Kong, P.A.3    Nyland, H.4    Pardo, C.A.5    Trapp, B.D.6
  • 11
    • 0042123685 scopus 로고    scopus 로고
    • Intracortical multiple sclerosis lesions are not associated with increased lymphocyte infiltration
    • (a)
    • Bo L, Vedeler CA, Nyland H, Trapp BD, Mork SJ (2003a) Intracortical multiple sclerosis lesions are not associated with increased lymphocyte infiltration. Mult Scler 9:323–331
    • (2003) Mult Scler , vol.9 , pp. 323-331
    • Bo, L.1    Vedeler, C.A.2    Nyland, H.3    Trapp, B.D.4    Mork, S.J.5
  • 13
    • 33846093882 scopus 로고    scopus 로고
    • Lack of correlation between cortical demyelination and white matter pathologic changes in multiple sclerosis
    • Bo L, Geurts JJ, van der Valk P, Polman C, Barkhof F (2007) Lack of correlation between cortical demyelination and white matter pathologic changes in multiple sclerosis. Arch Neurol 64: 76–80
    • (2007) Arch Neurol , vol.64 , pp. 76-80
    • Bo, L.1    Geurts, J.J.2    van der Valk, P.3    Polman, C.4    Barkhof, F.5
  • 16
    • 14844293538 scopus 로고    scopus 로고
    • The pathology of multiple sclerosis is location-dependent: No significant complement activation is detected in purely cortical lesions
    • Brink BP, Veerhuis R, Breij EC, van der Valk P, Dijkstra CD, Bo L (2005) The pathology of multiple sclerosis is location-dependent: no significant complement activation is detected in purely cortical lesions. J Neuropathol Exp Neurol 64:147–155
    • (2005) J Neuropathol Exp Neurol , vol.64 , pp. 147-155
    • Brink, B.P.1    Veerhuis, R.2    Breij, E.C.3    van der Valk, P.4    Dijkstra, C.D.5    Bo, L.6
  • 17
    • 0017855244 scopus 로고
    • The capillaries in acute and subacute multiple sclerosis plaques: A morphometric analysis
    • Brown WJ (1978) The capillaries in acute and subacute multiple sclerosis plaques: a morphometric analysis. Neurology 28:84–92
    • (1978) Neurology , vol.28 , pp. 84-92
    • Brown, W.J.1
  • 18
    • 0028843731 scopus 로고
    • Monocyte/macrophage differentiation in early multiple sclerosis lesions
    • Bruck W, Porada P, Poser S et al. (1995) Monocyte/macrophage differentiation in early multiple sclerosis lesions. Ann Neurol 38:788–796
    • (1995) Ann Neurol , vol.38 , pp. 788-796
    • Bruck, W.1    Porada, P.2    Poser, S.3
  • 19
    • 0037122960 scopus 로고    scopus 로고
    • Premyelinating oligodendrocytes in chronic lesions of multiple sclerosis
    • Chang A, Tourtellotte WW, Rudick R, Trapp BD (2002) Premyelinating oligodendrocytes in chronic lesions of multiple sclerosis. N Engl J Med 346:165–173
    • (2002) N Engl J Med , vol.346 , pp. 165-173
    • Chang, A.1    Tourtellotte, W.W.2    Rudick, R.3    Trapp, B.D.4
  • 21
    • 33644931322 scopus 로고    scopus 로고
    • Corticosteroids delay remyelination of experimental demyelination in the rodent central nervous system
    • Chari DM, Zhao C, Kotter MR, Blakemore WF, Franklin RJ (2006) Corticosteroids delay remyelination of experimental demyelination in the rodent central nervous system. J Neurosci Res 83:594–605
    • (2006) J Neurosci Res , vol.83 , pp. 594-605
    • Chari, D.M.1    Zhao, C.2    Kotter, M.R.3    Blakemore, W.F.4    Franklin, R.J.5
  • 23
  • 24
    • 33244466021 scopus 로고    scopus 로고
    • Natural history of multiple sclerosis: A unifying concept
    • Confavreux C, Vukusic S (2006) Natural history of multiple sclerosis: a unifying concept. Brain 129:606–616
    • (2006) Brain , vol.129 , pp. 606-616
    • Confavreux, C.1    Vukusic, S.2
  • 25
    • 0037819578 scopus 로고    scopus 로고
    • Abnormal sodium channel distribution in optic nerve axons in a model of inflammatory demyelination
    • Craner MJ, Lo AC, Black JA, Waxman SG (2003) Abnormal sodium channel distribution in optic nerve axons in a model of inflammatory demyelination. Brain 126:1552–1561
    • (2003) Brain , vol.126 , pp. 1552-1561
    • Craner, M.J.1    Lo, A.C.2    Black, J.A.3    Waxman, S.G.4
  • 27
    • 84974201150 scopus 로고
    • The histology of multiple sclerosis
    • Dawson JW (1916) The histology of multiple sclerosis. Trans R Soc Edinb 50:517–740
    • (1916) Trans R Soc Edinb , vol.50 , pp. 517-740
    • Dawson, J.W.1
  • 29
    • 0017645154 scopus 로고
    • Immunoglobulin-containing cells in multiple-sclerosis plaques
    • Esiri MM (1977) Immunoglobulin-containing cells in multiple-sclerosis plaques. Lancet 2:478
    • (1977) Lancet , vol.2 , pp. 478
    • Esiri, M.M.1
  • 30
    • 0034104079 scopus 로고    scopus 로고
    • Quantitative pathological evidence for axonal loss in normal appearing white matter in multiple sclerosis
    • (a)
    • Evangelou N, Esiri MM, Smith S, Palace J, Matthews PM (2000a) Quantitative pathological evidence for axonal loss in normal appearing white matter in multiple sclerosis. Ann Neurol 47:391–395
    • (2000) Ann Neurol , vol.47 , pp. 391-395
    • Evangelou, N.1    Esiri, M.M.2    Smith, S.3    Palace, J.4    Matthews, P.M.5
  • 31
    • 0033849266 scopus 로고    scopus 로고
    • Regional axonal loss in the corpus callosum correlates with cerebral white matter lesion volume and distribution in multiple sclerosis
    • (b)
    • Evangelou N, Konz D, Esiri MM, Smith S, Palace J, Matthews PM (2000b) Regional axonal loss in the corpus callosum correlates with cerebral white matter lesion volume and distribution in multiple sclerosis. Brain 123(Pt 9):1845–1849
    • (2000) Brain , vol.123 , pp. 1845-1849
    • Evangelou, N.1    Konz, D.2    Esiri, M.M.3    Smith, S.4    Palace, J.5    Matthews, P.M.6
  • 32
    • 0034840729 scopus 로고    scopus 로고
    • Size-selective neuronal changes in the anterior optic pathways suggest a differential susceptibility to injury in multiple sclerosis
    • Evangelou N, Konz D, Esiri MM, Smith S, Palace J, Matthews PM (2001) Size-selective neuronal changes in the anterior optic pathways suggest a differential susceptibility to injury in multiple sclerosis. Brain 124:1813–1820
    • (2001) Brain , vol.124 , pp. 1813-1820
    • Evangelou, N.1    Konz, D.2    Esiri, M.M.3    Smith, S.4    Palace, J.5    Matthews, P.M.6
  • 33
    • 7244226354 scopus 로고    scopus 로고
    • Increased expression of Nkx2.2 and Olig2 identifies reactive oligodendrocyte progenitor cells responding to demyelination in the adult CNS
    • Fancy SP, Zhao C, Franklin RJ (2004) Increased expression of Nkx2.2 and Olig2 identifies reactive oligodendrocyte progenitor cells responding to demyelination in the adult CNS. Mol Cell Neurosci 27:247–254
    • (2004) Mol Cell Neurosci , vol.27 , pp. 247-254
    • Fancy, S.P.1    Zhao, C.2    Franklin, R.J.3
  • 35
    • 0031002545 scopus 로고    scopus 로고
    • Axonal damage in acute multiple sclerosis lesions
    • Ferguson B, Matyszak MK, Esiri MM, Perry VH (1997) Axonal damage in acute multiple sclerosis lesions. Brain 120(Pt 3):393–399
    • (1997) Brain , vol.120 , pp. 393-399
    • Ferguson, B.1    Matyszak, M.K.2    Esiri, M.M.3    Perry, V.H.4
  • 36
    • 33644607018 scopus 로고    scopus 로고
    • Multiple sclerosis – the plaque and its pathogenesis
    • Frohman EM, Racke MK, Raine CS (2006) Multiple sclerosis – the plaque and its pathogenesis. N Engl J Med 354:942–955
    • (2006) N Engl J Med , vol.354 , pp. 942-955
    • Frohman, E.M.1    Racke, M.K.2    Raine, C.S.3
  • 37
    • 1842367972 scopus 로고    scopus 로고
    • The application of multifactorial cluster analysis in the staging of plaques in early multiple sclerosis. Identification and characterization of the primary demyelinating lesion
    • Gay FW, Drye TJ, Dick GW, Esiri MM (1997) The application of multifactorial cluster analysis in the staging of plaques in early multiple sclerosis. Identification and characterization of the primary demyelinating lesion. Brain 120(Pt 8):1461–1483
    • (1997) Brain , vol.120 , pp. 1461-1483
    • Gay, F.W.1    Drye, T.J.2    Dick, G.W.3    Esiri, M.M.4
  • 40
    • 60249099507 scopus 로고    scopus 로고
    • Regional variations in the extent and pattern of grey matter demyelination in multiple sclerosis: A comparison between the cerebral cortex, cerebellar cortex, deep grey matter nuclei and the spinal cord
    • Gilmore CP, Donaldson I, Bo L, Owens T, Lowe J, Evangelou N (2009) Regional variations in the extent and pattern of grey matter demyelination in multiple sclerosis: a comparison between the cerebral cortex, cerebellar cortex, deep grey matter nuclei and the spinal cord. J Neurol Neurosurg Psychiatry 80:182–187
    • (2009) J Neurol Neurosurg Psychiatry , vol.80 , pp. 182-187
    • Gilmore, C.P.1    Donaldson, I.2    Bo, L.3    Owens, T.4    Lowe, J.5    Evangelou, N.6
  • 41
    • 0027157685 scopus 로고
    • Failure of remyelination in areas of demyelination produced in the spinal cord of old rats
    • Gilson J, Blakemore WF (1993) Failure of remyelination in areas of demyelination produced in the spinal cord of old rats. Neuropathol Appl Neurobiol 19:173–181
    • (1993) Neuropathol Appl Neurobiol , vol.19 , pp. 173-181
    • Gilson, J.1    Blakemore, W.F.2
  • 42
    • 67650079567 scopus 로고    scopus 로고
    • Remyelination capacity of the MS brain decreases with disease chronicity
    • Goldschmidt T, Antel J, Konig FB, Bruck W, Kuhlmann T (2009) Remyelination capacity of the MS brain decreases with disease chronicity. Neurology 72:1914–1921
    • (2009) Neurology , vol.72 , pp. 1914-1921
    • Goldschmidt, T.1    Antel, J.2    Konig, F.B.3    Bruck, W.4    Kuhlmann, T.5
  • 43
    • 77952991172 scopus 로고    scopus 로고
    • Ocular pathology in multiple sclerosis: Retinal atrophy and inflammation irrespective of disease duration
    • Green AJ, McQuaid S, Hauser SL, Allen IV, Lyness R (2010) Ocular pathology in multiple sclerosis: retinal atrophy and inflammation irrespective of disease duration. Brain 133: 1591–1601
    • (2010) Brain , vol.133 , pp. 1591-1601
    • Green, A.J.1    McQuaid, S.2    Hauser, S.L.3    Allen, I.V.4    Lyness, R.5
  • 46
    • 0032968168 scopus 로고    scopus 로고
    • Tenascin-R and C in multiple sclerosis lesions: Relevance to extracellular matrix remodelling
    • Gutowski NJ, Newcombe J, Cuzner ML (1999) Tenascin-R and C in multiple sclerosis lesions: relevance to extracellular matrix remodelling. Neuropathol Appl Neurobiol 25:207–214
    • (1999) Neuropathol Appl Neurobiol , vol.25 , pp. 207-214
    • Gutowski, N.J.1    Newcombe, J.2    Cuzner, M.L.3
  • 49
    • 1642411203 scopus 로고    scopus 로고
    • Oligodendrocyte precursors on the move: Mechanisms directing migration
    • Jarjour AA, Kennedy TE (2004) Oligodendrocyte precursors on the move: mechanisms directing migration. Neuroscientist 10:99–105
    • (2004) Neuroscientist , vol.10 , pp. 99-105
    • Jarjour, A.A.1    Kennedy, T.E.2
  • 51
    • 0030785547 scopus 로고    scopus 로고
    • Identification of post-mitotic oligodendrocytes incapable of remyelination within the demyelinated adult spinal cord
    • Keirstead HS, Blakemore WF (1997) Identification of post-mitotic oligodendrocytes incapable of remyelination within the demyelinated adult spinal cord. J Neuropathol Exp Neurol 56:1191–1201
    • (1997) J Neuropathol Exp Neurol , vol.56 , pp. 1191-1201
    • Keirstead, H.S.1    Blakemore, W.F.2
  • 53
    • 70349577131 scopus 로고    scopus 로고
    • Meningeal inflammation is not associated with cortical demyelination in chronic multiple sclerosis
    • Kooi EJ, Geurts JJ, van Horssen J, Bo L, van der Valk P (2009) Meningeal inflammation is not associated with cortical demyelination in chronic multiple sclerosis. J Neuropathol Exp Neurol 68:1021–1028
    • (2009) J Neuropathol Exp Neurol , vol.68 , pp. 1021-1028
    • Kooi, E.J.1    Geurts, J.J.2    van Horssen, J.3    Bo, L.4    van der Valk, P.5
  • 54
    • 11844253894 scopus 로고    scopus 로고
    • Macrophage-depletion induced impairment of experimental CNS remyelination is associated with a reduced oligodendrocyte progenitor cell response and altered growth factor expression
    • Kotter MR, Zhao C, van Rooijen N, Franklin RJ (2005) Macrophage-depletion induced impairment of experimental CNS remyelination is associated with a reduced oligodendrocyte progenitor cell response and altered growth factor expression. Neurobiol Dis 18:166–175
    • (2005) Neurobiol Dis , vol.18 , pp. 166-175
    • Kotter, M.R.1    Zhao, C.2    van Rooijen, N.3    Franklin, R.J.4
  • 55
    • 46849098585 scopus 로고    scopus 로고
    • Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis
    • Kuhlmann T, Miron V, Cui Q, Wegner C, Antel J, Bruck W (2008) Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis. Brain 131:1749–1758
    • (2008) Brain , vol.131 , pp. 1749-1758
    • Kuhlmann, T.1    Miron, V.2    Cui, Q.3    Wegner, C.4    Antel, J.5    Bruck, W.6
  • 58
    • 0028089844 scopus 로고
    • Blood-brain barrier abnormalities in longstanding multiple sclerosis lesions. An immunohistochemical study
    • Kwon EE, Prineas JW (1994) Blood-brain barrier abnormalities in longstanding multiple sclerosis lesions. An immunohistochemical study. J Neuropathol Exp Neurol 53:625–636
    • (1994) J Neuropathol Exp Neurol , vol.53 , pp. 625-636
    • Kwon, E.E.1    Prineas, J.W.2
  • 59
    • 0020655874 scopus 로고
    • Comparative neuropathology of chronic experimental allergic encephalomyelitis and multiple sclerosis
    • Lassmann H (1983) Comparative neuropathology of chronic experimental allergic encephalomyelitis and multiple sclerosis. Schriftenr Neurol 25:1–135
    • (1983) Schriftenr Neurol , vol.25 , pp. 1-135
    • Lassmann, H.1
  • 60
    • 0032526198 scopus 로고    scopus 로고
    • Immunopathology of multiple sclerosis: Report on an international meeting held at the Institute of Neurology of the University of Vienna
    • Lassmann H, Raine CS, Antel J, Prineas JW (1998) Immunopathology of multiple sclerosis: report on an international meeting held at the Institute of Neurology of the University of Vienna. J Neuroimmunol 86:213–217
    • (1998) J Neuroimmunol , vol.86 , pp. 213-217
    • Lassmann, H.1    Raine, C.S.2    Antel, J.3    Prineas, J.W.4
  • 61
    • 80052959919 scopus 로고    scopus 로고
    • Epstein-Barr virus in the multiple sclerosis brain: A controversial issue – report on a focused workshop held in the Centre for Brain Research of the Medical University of Vienna, Austria
    • Lassmann H, Niedobitek G, Aloisi F, Middeldorp JM (2011) Epstein-Barr virus in the multiple sclerosis brain: a controversial issue – report on a focused workshop held in the Centre for Brain Research of the Medical University of Vienna, Austria. Brain 134:2772–2786
    • (2011) Brain , vol.134 , pp. 2772-2786
    • Lassmann, H.1    Niedobitek, G.2    Aloisi, F.3    Middeldorp, J.M.4
  • 62
    • 0032763125 scopus 로고    scopus 로고
    • Activation and proliferation of endogenous oligodendrocyte precursor cells during ethidium bromide-induced demyelination
    • Levine JM, Reynolds R (1999) Activation and proliferation of endogenous oligodendrocyte precursor cells during ethidium bromide-induced demyelination. Exp Neurol 160:333–347
    • (1999) Exp Neurol , vol.160 , pp. 333-347
    • Levine, J.M.1    Reynolds, R.2
  • 63
    • 33748437057 scopus 로고    scopus 로고
    • Females remyelinate more efficiently than males following demyelination in the aged but not young adult CNS
    • Li WW, Penderis J, Zhao C, Schumacher M, Franklin RJ (2006) Females remyelinate more efficiently than males following demyelination in the aged but not young adult CNS. Exp Neurol 202:250–254
    • (2006) Exp Neurol , vol.202 , pp. 250-254
    • Li, W.W.1    Penderis, J.2    Zhao, C.3    Schumacher, M.4    Franklin, R.J.5
  • 64
    • 77954473191 scopus 로고    scopus 로고
    • Myelin repair is accelerated by inactivating CXCR2 on nonhematopoietic cells
    • Liu L, Darnall L, Hu T, Choi K, Lane TE, Ransohoff RM (2010) Myelin repair is accelerated by inactivating CXCR2 on nonhematopoietic cells. J Neurosci 30:9074–9083
    • (2010) J Neurosci , vol.30 , pp. 9074-9083
    • Liu, L.1    Darnall, L.2    Hu, T.3    Choi, K.4    Lane, T.E.5    Ransohoff, R.M.6
  • 65
    • 0345633543 scopus 로고    scopus 로고
    • A quantitative analysis of oligodendrocytes in multiple sclerosis lesions. A study of 113 cases
    • Lucchinetti C, Bruck W, Parisi J, Scheithauer B, Rodriguez M, Lassmann H (1999) A quantitative analysis of oligodendrocytes in multiple sclerosis lesions. A study of 113 cases. Brain 122 (Pt 12):2279–2295
    • (1999) Brain , vol.122 , pp. 2279-2295
    • Lucchinetti, C.1    Bruck, W.2    Parisi, J.3    Scheithauer, B.4    Rodriguez, M.5    Lassmann, H.6
  • 66
    • 0342906187 scopus 로고    scopus 로고
    • Heterogeneity of multiple sclerosis lesions: Implications for the pathogenesis of demyelination
    • Lucchinetti C, Bruck W, Parisi J, Scheithauer B, Rodriguez M, Lassmann H (2000) Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination. Ann Neurol 47:707–717
    • (2000) Ann Neurol , vol.47 , pp. 707-717
    • Lucchinetti, C.1    Bruck, W.2    Parisi, J.3    Scheithauer, B.4    Rodriguez, M.5    Lassmann, H.6
  • 68
    • 34249700046 scopus 로고    scopus 로고
    • Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology
    • Magliozzi R, Howell O, Vora A, Serafini B, Nicholas R, Puopolo M, Reynolds R, Aloisi F (2007) Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology. Brain 130:1089–1104
    • (2007) Brain , vol.130 , pp. 1089-1104
    • Magliozzi, R.1    Howell, O.2    Vora, A.3    SeraFiNi, B.4    Nicholas, R.5    Puopolo, M.6    Reynolds, R.7    Aloisi, F.8
  • 69
    • 0000197889 scopus 로고
    • Die sogenannte “akute multiple sklerose” (encephalomyelitis periaxialis scleroticans)
    • Marburg O (1906) Die sogenannte “akute multiple sklerose” (encephalomyelitis periaxialis scleroticans). J Psychiatr Neurol 27: 217–312
    • (1906) J Psychiatr Neurol , vol.27 , pp. 217-312
    • Marburg, O.1
  • 70
    • 0036897351 scopus 로고    scopus 로고
    • Histone deacetylase activity is necessary for oligodendrocyte lineage progression
    • Marin-Husstege M, Muggironi M, Liu A, Casaccia-Bonnefil P (2002) Histone deacetylase activity is necessary for oligodendrocyte lineage progression. J Neurosci 22:10333–10345
    • (2002) J Neurosci , vol.22 , pp. 10333-10345
    • Marin-Husstege, M.1    Muggironi, M.2    Liu, A.3    Casaccia-Bonnefil, P.4
  • 71
    • 0028294594 scopus 로고
    • Expression and effects of hyaluronan and of the hyaluronan-binding protein hyaluronectin in newborn rat brain glial cell cultures
    • Marret S, Delpech B, Delpech A, Asou H, Girard N, Courel MN, Chauzy C, Maingonnat C, Fessard C (1994) Expression and effects of hyaluronan and of the hyaluronan-binding protein hyaluronectin in newborn rat brain glial cell cultures. J Neurochem 62:1285–1295
    • (1994) J Neurochem , vol.62 , pp. 1285-1295
    • Marret, S.1    Delpech, B.2    Delpech, A.3    Asou, H.4    Girard, N.5    Courel, M.N.6    Chauzy, C.7    Maingonnat, C.8    Fessard, C.9
  • 74
    • 61749099508 scopus 로고    scopus 로고
    • Abnormal expression of TIP30 and arrested nucleocytoplasmic transport within oligodendrocyte precursor cells in multiple sclerosis
    • Nakahara J, Kanekura K, Nawa M, Aiso S, Suzuki N (2009) Abnormal expression of TIP30 and arrested nucleocytoplasmic transport within oligodendrocyte precursor cells in multiple sclerosis. J Clin Invest 119:169–181
    • (2009) J Clin Invest , vol.119 , pp. 169-181
    • Nakahara, J.1    Kanekura, K.2    Nawa, M.3    Aiso, S.4    Suzuki, N.5
  • 77
    • 34247862406 scopus 로고    scopus 로고
    • Remyelination can be extensive in multiple sclerosis despite a long disease course
    • Patani R, Balaratnam M, Vora A, Reynolds R (2007) Remyelination can be extensive in multiple sclerosis despite a long disease course. Neuropathol Appl Neurobiol 33:277–287
    • (2007) Neuropathol Appl Neurobiol , vol.33 , pp. 277-287
    • Patani, R.1    Balaratnam, M.2    Vora, A.3    Reynolds, R.4
  • 79
    • 79952272438 scopus 로고    scopus 로고
    • Changed histone acetylation patterns in normal-appearing white matter and early multiple sclerosis lesions
    • Pedre X, Mastronardi F, Bruck W, Lopez-Rodas G, Kuhlmann T, Casaccia P (2011) Changed histone acetylation patterns in normal-appearing white matter and early multiple sclerosis lesions. J Neurosci 31:3435–3445
    • (2011) J Neurosci , vol.31 , pp. 3435-3445
    • Pedre, X.1    Mastronardi, F.2    Bruck, W.3    Lopez-Rodas, G.4    Kuhlmann, T.5    Casaccia, P.6
  • 80
    • 0013828898 scopus 로고
    • Electron microscopic features of multiple sclerosis lesions
    • Perier O, Gregoire A (1965) Electron microscopic features of multiple sclerosis lesions. Brain 88:937–952
    • (1965) Brain , vol.88 , pp. 937-952
    • Perier, O.1    Gregoire, A.2
  • 81
    • 0034842126 scopus 로고    scopus 로고
    • Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions
    • Peterson JW, Bo L, Mork S, Chang A, Trapp BD (2001) Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions. Ann Neurol 50:389–400
    • (2001) Ann Neurol , vol.50 , pp. 389-400
    • Peterson, J.W.1    Bo, L.2    Mork, S.3    Chang, A.4    Trapp, B.D.5
  • 83
    • 0036211141 scopus 로고    scopus 로고
    • Abnormal endothelial tight junctions in active lesions and normal-appearing white matter in multiple sclerosis
    • Plumb J, McQuaid S, Mirakhur M, Kirk J (2002) Abnormal endothelial tight junctions in active lesions and normal-appearing white matter in multiple sclerosis. Brain Pathol 12:154–169
    • (2002) Brain Pathol , vol.12 , pp. 154-169
    • Plumb, J.1    McQuaid, S.2    Mirakhur, M.3    Kirk, J.4
  • 84
  • 85
    • 0017848577 scopus 로고
    • The fine structure of chronically active multiple sclerosis plaques
    • Prineas JW, Connell F (1978) The fine structure of chronically active multiple sclerosis plaques. Neurology 28:68–75
    • (1978) Neurology , vol.28 , pp. 68-75
    • Prineas, J.W.1    Connell, F.2
  • 86
    • 0018410045 scopus 로고
    • Remyelination in multiple sclerosis
    • Prineas JW, Connell F (1979) Remyelination in multiple sclerosis. Ann Neurol 5:22–31
    • (1979) Ann Neurol , vol.5 , pp. 22-31
    • Prineas, J.W.1    Connell, F.2
  • 87
    • 0019469331 scopus 로고
    • Multiple sclerosis: Capping of surface immunoglobulin G on macrophages engaged in myelin breakdown
    • Prineas JW, Graham JS (1981) Multiple sclerosis: capping of surface immunoglobulin G on macrophages engaged in myelin breakdown. Ann Neurol 10:149–158
    • (1981) Ann Neurol , vol.10 , pp. 149-158
    • Prineas, J.W.1    Graham, J.S.2
  • 90
    • 0027173943 scopus 로고
    • Multiple sclerosis: Remyelination in acute lesions
    • Raine CS, Wu E (1993) Multiple sclerosis: remyelination in acute lesions. J Neuropathol Exp Neurol 52:199–204
    • (1993) J Neuropathol Exp Neurol , vol.52 , pp. 199-204
    • Raine, C.S.1    Wu, E.2
  • 91
    • 0028132773 scopus 로고
    • A comparison of the pathology of primary and secondary progressive multiple sclerosis
    • Revesz T, Kidd D, Thompson AJ, Barnard RO, McDonald WI (1994) A comparison of the pathology of primary and secondary progressive multiple sclerosis. Brain 117(Pt 4):759–765
    • (1994) Brain , vol.117 , pp. 759-765
    • Revesz, T.1    Kidd, D.2    Thompson, A.J.3    Barnard, R.O.4    McDonald, W.I.5
  • 93
    • 0027524603 scopus 로고
    • On classification of post-mortem multiple sclerosis plaques for neuroscientists
    • Sanders V, Conrad AJ, Tourtellotte WW (1993) On classification of post-mortem multiple sclerosis plaques for neuroscientists. J Neuroimmunol 46:207–216
    • (1993) J Neuroimmunol , vol.46 , pp. 207-216
    • Sanders, V.1    Conrad, A.J.2    Tourtellotte, W.W.3
  • 96
    • 2442708947 scopus 로고    scopus 로고
    • Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis
    • Serafini B, Rosicarelli B, Magliozzi R, Stigliano E, Aloisi F (2004) Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis. Brain Pathol 14:164–174
    • (2004) Brain Pathol , vol.14 , pp. 164-174
    • Serafini, B.1    Rosicarelli, B.2    Magliozzi, R.3    Stigliano, E.4    Aloisi, F.5
  • 97
    • 22344446199 scopus 로고    scopus 로고
    • Histone modifications affect timing of oligodendrocyte progenitor differentiation in the developing rat brain
    • Shen S, Li J, Casaccia-Bonnefil P (2005) Histone modifications affect timing of oligodendrocyte progenitor differentiation in the developing rat brain. J Cell Biol 169:577–589
    • (2005) J Cell Biol , vol.169 , pp. 577-589
    • Shen, S.1    Li, J.2    Casaccia-Bonnefil, P.3
  • 99
    • 0033215282 scopus 로고    scopus 로고
    • Remyelination occurs as extensively but more slowly in old rats compared to young rats following gliotoxin-induced CNS demyelination
    • Shields SA, Gilson JM, Blakemore WF, Franklin RJ (1999) Remyelination occurs as extensively but more slowly in old rats compared to young rats following gliotoxin-induced CNS demyelination. Glia 28:77–83
    • (1999) Glia , vol.28 , pp. 77-83
    • Shields, S.A.1    Gilson, J.M.2    Blakemore, W.F.3    Franklin, R.J.4
  • 100
    • 20444363086 scopus 로고    scopus 로고
    • Wnt signaling controls the timing of oligodendrocyte development in the spinal cord
    • Shimizu T, Kagawa T, Wada T, Muroyama Y, Takada S, Ikenaka K (2005) Wnt signaling controls the timing of oligodendrocyte development in the spinal cord. Dev Biol 282:397–410
    • (2005) Dev Biol , vol.282 , pp. 397-410
    • Shimizu, T.1    Kagawa, T.2    Wada, T.3    Muroyama, Y.4    Takada, S.5    Ikenaka, K.6
  • 101
    • 0036549138 scopus 로고    scopus 로고
    • The age-related decrease in CNS remyelination efficiency is attributable to an impairment of both oligodendrocyte progenitor recruitment and differentiation
    • Sim FJ, Zhao C, Penderis J, Franklin RJ (2002) The age-related decrease in CNS remyelination efficiency is attributable to an impairment of both oligodendrocyte progenitor recruitment and differentiation. J Neurosci 22:2451–2459
    • (2002) J Neurosci , vol.22 , pp. 2451-2459
    • Sim, F.J.1    Zhao, C.2    Penderis, J.3    Franklin, R.J.4
  • 102
    • 77954893581 scopus 로고    scopus 로고
    • Hyaluronan blocks oligodendrocyte progenitor maturation and remyelination through TLR2
    • Sloane JA, Batt C, Ma Y, Harris ZM, Trapp B, Vartanian T (2010) Hyaluronan blocks oligodendrocyte progenitor maturation and remyelination through TLR2. Proc Natl Acad Sci USA 107:11555–11560
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 11555-11560
    • Sloane, J.A.1    Batt, C.2    Ma, Y.3    Harris, Z.M.4    Trapp, B.5    Vartanian, T.6
  • 103
    • 0028938139 scopus 로고
    • Vitronectin and integrin vitronectin receptor localization in multiple sclerosis lesions
    • Sobel RA, Chen M, Maeda A, Hinojoza JR (1995) Vitronectin and integrin vitronectin receptor localization in multiple sclerosis lesions. J Neuropathol Exp Neurol 54:202–213
    • (1995) J Neuropathol Exp Neurol , vol.54 , pp. 202-213
    • Sobel, R.A.1    Chen, M.2    Maeda, A.3    Hinojoza, J.R.4
  • 104
    • 0036154041 scopus 로고    scopus 로고
    • BDNF and gp145trkB in multiple sclerosis brain lesions: Neuroprotective interactions between immune and neuronal cells?
    • Stadelmann C, Kerschensteiner M, Misgeld T, Bruck W, Hohlfeld R, Lassmann H (2002) BDNF and gp145trkB in multiple sclerosis brain lesions: neuroprotective interactions between immune and neuronal cells? Brain 125:75–85
    • (2002) Brain , vol.125 , pp. 75-85
    • Stadelmann, C.1    Kerschensteiner, M.2    Misgeld, T.3    Bruck, W.4    Hohlfeld, R.5    Lassmann, H.6
  • 106
    • 66549110162 scopus 로고    scopus 로고
    • Greater loss of axons in primary progressive multiple sclerosis plaques compared to secondary progressive disease
    • Tallantyre EC, Bo L, Al-Rawashdeh O, Owens T, Polman CH, Lowe J, Evangelou N (2009) Greater loss of axons in primary progressive multiple sclerosis plaques compared to secondary progressive disease. Brain 132:1190–1199
    • (2009) Brain , vol.132 , pp. 1190-1199
    • Tallantyre, E.C.1    Bo, L.2    Al-Rawashdeh, O.3    Owens, T.4    Polman, C.H.5    Lowe, J.6    Evangelou, N.7
  • 107
    • 0029970104 scopus 로고    scopus 로고
    • Failure to achieve remyelination of demyelinated rat axons following transplantation of glial cells obtained from the adult human brain
    • Targett MP, Sussman J, Scolding N, O’Leary MT, Compston DA, Blakemore WF (1996) Failure to achieve remyelination of demyelinated rat axons following transplantation of glial cells obtained from the adult human brain. Neuropathol Appl Neurobiol 22:199–206
    • (1996) Neuropathol Appl Neurobiol , vol.22 , pp. 199-206
    • Targett, M.P.1    Sussman, J.2    Scolding, N.3    O’Leary, M.T.4    Compston, D.A.5    Blakemore, W.F.6
  • 110
    • 0034062423 scopus 로고    scopus 로고
    • Staging of multiple sclerosis (MS) lesions: Pathology of the time frame of MS
    • van der Valk P, De Groot CJ (2000) Staging of multiple sclerosis (MS) lesions: pathology of the time frame of MS. Neuropathol Appl Neurobiol 26:2–10
    • (2000) Neuropathol Appl Neurobiol , vol.26 , pp. 2-10
    • van der Valk, P.1    de Groot, C.J.2
  • 113
    • 0037106212 scopus 로고    scopus 로고
    • Differentiation of proliferated NG2-positive glial progenitor cells in a remyelinating lesion
    • Watanabe M, Toyama Y, Nishiyama A (2002) Differentiation of proliferated NG2-positive glial progenitor cells in a remyelinating lesion. J Neurosci Res 69:826–836
    • (2002) J Neurosci Res , vol.69 , pp. 826-836
    • Watanabe, M.1    Toyama, Y.2    Nishiyama, A.3
  • 115
    • 0031962240 scopus 로고    scopus 로고
    • Chronic stage multiple sclerosis lesions contain a relatively quiescent population of oligodendrocyte precursor cells
    • (a)
    • Wolswijk G (1998a) Chronic stage multiple sclerosis lesions contain a relatively quiescent population of oligodendrocyte precursor cells. J Neurosci 18:601–609
    • (1998) J Neurosci , vol.18 , pp. 601-609
    • Wolswijk, G.1
  • 116
    • 0031772824 scopus 로고    scopus 로고
    • Oligodendrocyte regeneration in the adult rodent CNS and the failure of this process in multiple sclerosis
    • (b)
    • Wolswijk G (1998b) Oligodendrocyte regeneration in the adult rodent CNS and the failure of this process in multiple sclerosis. Prog Brain Res 117:233–247
    • (1998) Prog Brain Res , vol.117 , pp. 233-247
    • Wolswijk, G.1
  • 117
    • 0033962548 scopus 로고    scopus 로고
    • Oligodendrocyte survival, loss and birth in lesions of chronic-stage multiple sclerosis
    • Wolswijk G (2000) Oligodendrocyte survival, loss and birth in lesions of chronic-stage multiple sclerosis. Brain 123(Pt 1):105–115
    • (2000) Brain , vol.123 , pp. 105-115
    • Wolswijk, G.1
  • 118
    • 0036158610 scopus 로고    scopus 로고
    • Oligodendrocyte precursor cells in the demyelinated multiple sclerosis spinal cord
    • Wolswijk G (2002) Oligodendrocyte precursor cells in the demyelinated multiple sclerosis spinal cord. Brain 125:338–349
    • (2002) Brain , vol.125 , pp. 338-349
    • Wolswijk, G.1
  • 120
  • 121
    • 0033616730 scopus 로고    scopus 로고
    • Adult brain retains the potential to generate oligodendroglial progenitors with extensive myelination capacity
    • Zhang SC, Ge B, Duncan ID (1999) Adult brain retains the potential to generate oligodendroglial progenitors with extensive myelination capacity. Proc Natl Acad Sci USA 96:4089–4094
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 4089-4094
    • Zhang, S.C.1    Ge, B.2    Duncan, I.D.3
  • 122
    • 73149124029 scopus 로고    scopus 로고
    • Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination
    • Zhang Y, et al. (2009) Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination. Proc Natl Acad Sci USA 106:19162–19167
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 19162-19167
    • Zhang, Y.1


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