Excess iron modulates endoplasmic reticulum stress-associated pathways in a mouse model of alcohol and high-fat diet-induced liver injury

Laboratory Investigation

Volumn 93, Issue 12, 2013, Pages 1295-1312

  Tan, Terrence C H ^a,b,c   Crawford, Darrell H G ^a,b   Jaskowski, Lesley A ^a,b   Subramaniam, V Nathan ^a,b,d   Clouston, Andrew D ^a   Crane, Denis I ^e   Bridle, Kim R ^a,b   Anderson, Gregory J ^d   Fletcher, Linda M ^a,c  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b GREENSLOPES PRIVATE HOSPITAL   (Australia)

^c PRINCESS ALEXANDRA HOSPITAL   (Australia)

^d QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^e GRIFFITH UNIVERSITY   (Australia)

Author keywords

autophagy; endoplasmic reticulum stress; HFE; iron overload; unfolded protein response

Indexed keywords

ALCOHOL; BECLIN 1; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; IRON; PROTEIN P62; X BOX BINDING PROTEIN 1; TOLL LIKE RECEPTOR; TRACE ELEMENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; AUTOPHAGY; CONJUGATION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; IRON OVERLOAD; LIPID DIET; LIVER CIRRHOSIS; LIVER INJURY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; UNFOLDED PROTEIN RESPONSE; ANIMAL; BLOOD; C57BL MOUSE; COMPLICATION; DISEASE MODEL; DRINKING BEHAVIOR; DRUG EFFECTS; FATTY LIVER, ALCOHOLIC; METABOLISM; OBESITY; PATHOLOGY; RANDOMIZATION;

ALCOHOL DRINKING; ANIMALS; APOPTOSIS; AUTOPHAGY; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; ENDOPLASMIC RETICULUM STRESS; FATTY LIVER, ALCOHOLIC; IRON; MALE; MICE; MICE, INBRED C57BL; OBESITY; RANDOM ALLOCATION; TOLL-LIKE RECEPTORS; TRACE ELEMENTS;

EID: 84888375545     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2013.121     Document Type: Article

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