Knockout of an endogenous mannosyltransferase increases the homogeneity of glycoproteins produced in Pichia pastoris

Scientific Reports

Volumn 3, Issue , 2013, Pages

  Krainer, Florian W ^a   Gmeiner, Christoph ^b   Neutsch, Lukas ^c   Windwarder, Markus ^d   Pletzenauer, Robert ^b   Herwig, Christoph ^b   Altmann, Friedrich ^d   Glieder, Anton ^e   Spadiut, Oliver ^b  

^a GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

^b VIENNA UNIVERSITY OF TECHNOLOGY   (Austria)

^c UNIVERSITY OF VIENNA   (Austria)

^d UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES   (Austria)

^e AUSTRIAN CENTRE OF INDUSTRIAL BIOTECHNOLOGY   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGAL PROTEIN; GLYCOPROTEIN; MANNOSE BINDING LECTIN; MANNOSYLTRANSFERASE; POLYSACCHARIDE; RECOMBINANT PROTEIN;

ARTICLE; BATCH CELL CULTURE; BIOREACTOR; CELL DIVISION; CHEMISTRY; ENZYME ACTIVATION; GENE INACTIVATION; GENE ORDER; GENE TARGETING; GENETICS; GROWTH, DEVELOPMENT AND AGING; ISOLATION AND PURIFICATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; PHENOTYPE; PHYSIOLOGICAL STRESS; PICHIA;

BATCH CELL CULTURE TECHNIQUES; BIOREACTORS; CELL DIVISION; CHROMATOGRAPHY, LIQUID; ENZYME ACTIVATION; FUNGAL PROTEINS; GENE KNOCKOUT TECHNIQUES; GENE ORDER; GENE TARGETING; GLYCOPROTEINS; MANNOSE-BINDING LECTINS; MANNOSYLTRANSFERASES; MASS SPECTROMETRY; PHENOTYPE; PICHIA; POLYSACCHARIDES; RECOMBINANT PROTEINS; STRESS, PHYSIOLOGICAL;

EID: 84888260046     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep03279     Document Type: Article

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