Metabolism of free oligosaccharides is facilitated in the och1Δ mutant of Saccharomyces cerevisiae

Glycobiology

Volumn 21, Issue 10, 2011, Pages 1341-1348

  Hirayama, Hiroto ^a   Suzuki, Tadashi ^a  

^a RIKEN   (Japan)

Author keywords

mannosidase; cell wall stress; free oligosaccharides; N glycan; yeast

Indexed keywords

ALPHA 1,6 MANNOSYLTRANSFERASE; ALPHA MANNOSIDASE; GLYCAN DERIVATIVE; MANNOSE; MANNOSYLTRANSFERASE; OLIGOSACCHARIDE; UNCLASSIFIED DRUG;

ARTICLE; BIODEGRADATION; BIOSYNTHESIS; CARBOHYDRATE METABOLISM; CATABOLISM; CELL WALL; CELL WALL STRESS; CONFORMATIONAL TRANSITION; ENZYME ACTIVATION; ENZYME MECHANISM; FUNGUS MUTANT; GOLGI COMPLEX; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MODIFICATION; SACCHAROMYCES CEREVISIAE; STRUCTURE ANALYSIS;

ALPHA-MANNOSIDASE; GOLGI APPARATUS; MANNOSE; MANNOSYLTRANSFERASES; MEMBRANE GLYCOPROTEINS; MUTATION; OLIGOSACCHARIDES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; UP-REGULATION;

EUKARYOTA; SACCHAROMYCES CEREVISIAE; SACCHAROMYCETALES;

EID: 80052647770     PISSN: 09596658     EISSN: 14602423     Source Type: Journal    
DOI: 10.1093/glycob/cwr073     Document Type: Article

References (38)

1. Aebi M, Bernasconi R, Clerc S, Molinari M. 2010. N-glycan structures: Recognition and processing in the ER. Trends Biochem Sci. 35:74-82.
2. Anumula KR, Spiro RG. 1983. Release of glucose-containing polymannose oligosaccharides during glycoprotein biosynthesis. Studies with thyroid microsomal enzymes and slices. J Biol Chem. 258:15274-15282. (Pubitemid 14178958)
3. Chantret I, Frenoy JP, Moore SE. 2003. Free-oligosaccharide control in the yeast Saccharomyces cerevisiae: Roles for peptide: N-glycanase (Png1p) and vacuolar mannosidase (Ams1p). Biochem J. 373:901-908. (Pubitemid 36981100)
4. Chantret I, Moore SE. 2008. Free oligosaccharide regulation during mammalian protein N-glycosylation. Glycobiology. 18:210-224. (Pubitemid 351359688)
5. Gao N, Shang J, Lehrman MA. 2005. Analysis of glycosylation in CDG-Ia fibroblasts by fluorophore-assisted carbohydrate electrophoresis: Implications for extracellular glucose and intracellular mannose 6-phosphate. J Biol Chem. 280:17901-17909. (Pubitemid 41389031)
6. Haga Y, Totani K, Ito Y, Suzuki T. 2009. Establishment of a real-time analytical method for free oligosaccharide transport from the ER to the cytosol. Glycobiology. 19:987-994.
7. Hase S. 1994. High-performance liquid chromatography of pyridylaminated saccharides. Methods Enzymol. 230:225-237.
8. Helenius A, Aebi M. 2004. Roles of N-linked glycans in the endoplasmic reticulum. Annu Rev Biochem. 73:1019-1049. (Pubitemid 39050393)
9. Hirayama H, Seino J, Kitajima T, Jigami Y, Suzuki T. 2010. Free oligosaccharides to monitor glycoprotein endoplasmic reticulum-associated degradation in Saccharomyces cerevisiae. J Biol Chem. 285:12390-12404.
10. Iwai K, Mega T, Hase S. 1999. Detection of Man5GlcNAc and related free oligomannosides in the cytosol fraction of hen oviduct. J Biochem. 125:70-74. (Pubitemid 29085964)
11. Jelinek-Kelly S, Akiyama T, Saunier B, Tkacz JS, Herscovics A. 1985. Characterization of a specific alpha-mannosidase involved in oligosaccharide processing in Saccharomyces cerevisiae. J Biol Chem. 260:2253-2257. (Pubitemid 15105724)
12. Kato T, Kitamura K, Maeda M, Kimura Y, Katayama T, Ashida H, Yamamoto K. 2007. Free oligosaccharides in the cytosol of Caenorhabditis elegans are generated through endoplasmic reticulum-golgi trafficking. J Biol Chem. 282:22080-22088. (Pubitemid 47195757)
13. Kato A, Wang L, Ishii K, Seino J, Asano N, Suzuki T. 2011. Calystegine B3 as a specific inhibitor for cytoplasmic α-mannosidase, Man2C1. J Biochem. 149:415-422.
14. Kornfeld R, Kornfeld S. 1985. Assembly of asparagine-linked oligosaccharides. Annu Rev Biochem. 54:631-664. (Pubitemid 15073660)
15. Kuranda MJ, Robbins PW. 1987. Cloning and heterologous expression of glycosidase genes from Saccharomyces cerevisiae. Proc Natl Acad Sci USA. 84:2585-2589. (Pubitemid 17064697)
16. Lehle L, Eiden A, Lehnert K, Haselbeck A, Kopetzki E. 1995. Glycoprotein biosynthesis in Saccharomyces cerevisiae: ngd29, an N-glycosylation mutant allelic to och1 having a defect in the initiation of outer chain formation. FEBS Lett. 370:41-45.
17. Lehle L, Strahl S, Tanner W. 2006. Protein glycosylation, conserved from yeast to man: A model organism helps elucidate congenital human diseases. Angew Chem Int Ed Engl. 45:6802-6818. (Pubitemid 44654465)
18. Moore SE, Bauvy C, Codogno P. 1995. Endoplasmic reticulum-to-cytosol transport of free polymannose oligosaccharides in permeabilized HepG2 cells. EMBO J. 14:6034-6042.
19. Nagasu T, Shimma Y, Nakanishi Y, Kuromitsu J, Iwama K, Nakayama K, Suzuki K, Jigami Y. 1992. Isolation of new temperature-sensitive mutants of Saccharomyces cerevisiae deficient in mannose outer chain elongation. Yeast. 8:535-547.
20. Nakanishi-Shindo Y, Nakayama K, Tanaka A, Toda Y, Jigami Y. 1993. Structure of the N-linked oligosaccharides that show the complete loss of α-1,6-polymannose outer chain from och1, och1 mnn1, and och1 mnn1 alg3 mutants of Saccharomyces cerevisiae. J Biol Chem. 268:26338-26345. (Pubitemid 23361707)
21. Nakayama K, Nagasu T, Shimma Y, Kuromitsu J, Jigami Y. 1992. OCH1 encodes a novel membrane bound mannosyltransferase: Outer chain elongation of asparagine-linked oligosaccharides. EMBO J. 11:2511-2519.
22. Ohashi T, Ikeda Y, Tanaka N, Nakakita S, Natsuka S, Giga-Hama Y, Takegawa K. 2009. The och1 mutant of Schizosaccharomyces pombe produces galactosylated core structures of N-linked oligosaccharides. Biosci Biotechnol Biochem. 73:407-414.
23. Ohashi S, Iwai K, Mega T, Hase S. 1999. Quantitation and isomeric structure analysis of free oligosaccharides present in the cytosol fraction of mouse liver: Detection of a free disialobiantennary oligosaccharide and glucosylated oligomannosides. J Biochem. 126:852-858.
24. Opheim DJ. 1978. α-D-mannosidase of Saccharomyces cerevisiae. Characterization and modulation of activity. Biochim Biophys Acta. 524:121-130. (Pubitemid 8336029)
25. Saint-Pol A, Bauvy C, Codogno P, Moore SE. 1997. Transfer of free polymannose-type oligosaccharides from the cytosol to lysosomes in cultured human hepatocellular carcinoma HepG2 cells. J Cell Biol. 136:45-59. (Pubitemid 27044803)
26. Scrimale T, Didone L, de Mesy Bentley KL, Krysan DJ. 2009. The unfolded protein response is induced by the cell wall integrity mitogen-activated protein kinase signaling cascade and is required for cell wall integrity in Saccharomyces cerevisiae. Mol Biol Cell. 20:164-175.
27. Spiro RG. 2004. Role of N-linked polymannose oligosaccharides in targeting glycoproteins for endoplasmic reticulum-associated degradation. Cell Mol Life Sci. 61:1025-1041. (Pubitemid 38626507)
28. Suzuki T. 2007. Cytoplasmic peptide:N-glycanase and catabolic pathway for free N-glycans in the cytosol. Semin Cell Dev Biol. 18:762-769. (Pubitemid 350138448)
29. Suzuki T. 2009. Introduction to glycometabolome. Trends Glycosci Glycotechnol. 21:219-227.
30. Suzuki T, Funakoshi Y. 2006. Free N-linked oligosaccharide chains: Formation and degradation. Glycoconj J. 23:291-302. (Pubitemid 44198254)
31. Suzuki T, Hara I, Nakano M, Shigeta M, Nakagawa T, Kondo A, Funakoshi Y, Taniguchi N. 2006. Man2C1, an alpha-mannosidase, is involved in the trimming of free oligosaccharides in the cytosol. Biochem J. 400:33-41. (Pubitemid 44763817)
32. Suzuki T, Kitajima K, Emori Y, Inoue Y, Inoue S. 1997. Site-specific de-N-glycosylation of diglycosylated ovalbumin in hen oviduct by endogenous peptide: N-glycanase as a quality control system for newly synthesized proteins. Proc Natl Acad Sci USA. 94:6244-6249. (Pubitemid 27270669)
33. Suzuki T, Matsuo I, Totani K, Funayama S, Seino J, Taniguchi N, Ito Y, Hase S. 2008. Dual-gradient high-performance liquid chromatography for identification of cytosolic high-mannose-type free glycans. Anal Biochem. 381:224-232.
34. Suzuki T, Yano K, Sugimoto S, Kitajima K, Lennarz WJ, Inoue S, Inoue Y, Emori Y. 2002. Endo-beta-N-acetylglucosaminidase, an enzyme involved in processing of free oligosaccharides in the cytosol. Proc Natl Acad Sci USA. 99:9691-9696. (Pubitemid 34831109)
35. Travers KJ, Patil CK, Wodicka L, Lockhart DJ, Weissman JS, Walter P. 2000. Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation. Cell. 101:249-258.
36. Trombetta ES, Parodi AJ. 2003. Quality control and protein folding in the secretory pathway. Annu Rev Cell Dev Biol. 19:649-676. (Pubitemid 37487364)
37. Varki A. 1993. Biological roles of oligosaccharides: All of the theories are correct. Glycobiology. 3:97-130. (Pubitemid 23132602)
38. Yanagida K, Natsuka S, Hase S. 2006. Structural diversity of cytosolic free oligosaccharides in the human hepatoma cell line, HepG2. Glycobiology. 16:294-304.