Tat-glyoxalase protein inhibits against ischemic neuronal cell damage and ameliorates ischemic injury

Free Radical Biology and Medicine

Volumn 67, Issue , 2014, Pages 195-210

  Shin, Min Jea ^a   Kim, Dae Won ^b   Lee, Yeom Pyo ^a   Ahn, Eun Hee ^a   Jo, Hyo Sang ^a   Kim, Duk Soo ^c   Kwon, Oh Shin ^d   Kang, Tae Cheon ^a   Cho, Yong Jun ^a   Park, Jinseu ^a   Eum, Won Sik ^a   Choi, Soo Young ^a  

^a Hallym University   (South Korea)

^b Gangneung Wonju National University   (South Korea)

^c Soonchunhyang University   (South Korea)

^d Kyungpook National University   (South Korea)

Author keywords

Glyoxalase (GLO); Ischemic damage; Methylglyoxal (MG); Oxidative stress; Protein therapy

Indexed keywords

CASPASE 3; GLYOXALASE; LACTIC ACID; METHYLGLYOXAL; MITOGEN ACTIVATED PROTEIN KINASE; NEUROPROTECTIVE AGENT; TRANSACTIVATOR PROTEIN; ADVANCED GLYCATION END PRODUCT; CASPASE 9; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE; TAT GLYOXALASE 1 PROTEIN; TAT GLYOXALASE 2 PROTEIN; UNCLASSIFIED DRUG; CASP3 PROTEIN, MOUSE; HYBRID PROTEIN; HYDROGEN PEROXIDE; HYDROXYACYLGLUTATHIONE HYDROLASE; LACTOYLGLUTATHIONE LYASE; THIOL ESTER HYDROLASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG EFFECT; DRUG INHIBITION; ENZYME ACTIVATION; GERBIL; GLYCATION; HIPPOCAMPAL CA1 REGION; HYPOXIC ISCHEMIC ENCEPHALOPATHY; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NERVE CELL LESION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; APOPTOSIS; BLOOD BRAIN BARRIER; BRAIN ISCHEMIA; CELL DEATH; CELL VIABILITY; CELL VIABILITY ASSAY; CONCENTRATION RESPONSE; CYTOTOXICITY; ENZYME PHOSPHORYLATION; GERBIL MODEL; IMMUNOHISTOCHEMISTRY; NERVE CELL; NICK END LABELING; OXIDATIVE STRESS; POLYACRYLAMIDE GEL ELECTROPHORESIS; WESTERN BLOTTING; WILD TYPE; ANIMAL; CELL LINE; DRUG EFFECTS; GENE EXPRESSION; GENETICS; METABOLISM; PATHOLOGY;

ANIMALIA; GERBILLINAE;

ANIMALS; APOPTOSIS; BRAIN ISCHEMIA; CA1 REGION, HIPPOCAMPAL; CASPASE 3; CELL LINE; DNA FRAGMENTATION; GENE EXPRESSION; GENE PRODUCTS, TAT; GERBILLINAE; GLYCOSYLATION END PRODUCTS, ADVANCED; HYDROGEN PEROXIDE; LACTOYLGLUTATHIONE LYASE; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NEURONS; OXIDATIVE STRESS; PYRUVALDEHYDE; RECOMBINANT FUSION PROTEINS; THIOLESTER HYDROLASES;

EID: 84888259787     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2013.10.815     Document Type: Article

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