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Volumn 1820, Issue 10, 2012, Pages 1647-1655

PEP-1-metallothionein-III protein ameliorates the oxidative stress-induced neuronal cell death and brain ischemic insults

Author keywords

Antioxidant; Cell viability; Ischemia; PEP 1 MT III; Protein transduction; ROS

Indexed keywords

ANTIOXIDANT; HYBRID PROTEIN; METALLOTHIONEIN III; PEP 1 PEPTIDE METALLOTHIONEIN III FUSION PROTEIN; UNCLASSIFIED DRUG;

EID: 84863745078     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2012.06.012     Document Type: Article
Times cited : (25)

References (61)
  • 1
    • 44649152946 scopus 로고    scopus 로고
    • Metallothionein in the central nervous system: Roles in protection, regeneration and cognition
    • A.K. West, J. Hidalgo, D. Eddins, E.D. Levin, and M. Aschner Metallothionein in the central nervous system: roles in protection, regeneration and cognition Neurotoxicol. 29 2008 489 503
    • (2008) Neurotoxicol. , vol.29 , pp. 489-503
    • West, A.K.1    Hidalgo, J.2    Eddins, D.3    Levin, E.D.4    Aschner, M.5
  • 2
    • 0038406726 scopus 로고    scopus 로고
    • Metallothioneins: New functional and structural insights
    • M. Vasak, and D.W. Hasler Metallothioneins: new functional and structural insights Curr. Opin. Chem. Biol. 4 2000 177 183
    • (2000) Curr. Opin. Chem. Biol. , vol.4 , pp. 177-183
    • Vasak, M.1    Hasler, D.W.2
  • 3
    • 84940629830 scopus 로고
    • Growth inhibitory factor, metallothionein-like protein and neuro-degenerative diseases
    • Y. Uchida Growth inhibitory factor, metallothionein-like protein and neuro-degenerative diseases Biol. Signals 3 1994 211 215
    • (1994) Biol. Signals , vol.3 , pp. 211-215
    • Uchida, Y.1
  • 4
    • 0032555204 scopus 로고    scopus 로고
    • The elusive function of metallothioneins
    • R.D. Palmiter The elusive function of metallothioneins Proc. Natl. Acad. Sci. U. S. A. 95 1998 8428 8430
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 8428-8430
    • Palmiter, R.D.1
  • 5
    • 0035872463 scopus 로고    scopus 로고
    • Roles of the metallothionein family of proteins in central nervous system
    • J. Hidalgo, M. Aschner, P. Zatta, and M. Vasak Roles of the metallothionein family of proteins in central nervous system Brain Res. Bull. 55 2001 133 145
    • (2001) Brain Res. Bull. , vol.55 , pp. 133-145
    • Hidalgo, J.1    Aschner, M.2    Zatta, P.3    Vasak, M.4
  • 7
    • 0031818254 scopus 로고    scopus 로고
    • Expression of the gene encoding metallothionein-3 in organs of the reproductive system
    • P. Moffatt, and C. Seguin Expression of the gene encoding metallothionein-3 in organs of the reproductive system DNA Cell. Biol. 17 1998 501 510
    • (1998) DNA Cell. Biol. , vol.17 , pp. 501-510
    • Moffatt, P.1    Seguin, C.2
  • 8
    • 0028263925 scopus 로고
    • Enhanced neurotrophic activity in Alzheimer's disease cortex is not associated with down-regulation of metallothionein-III (GIF)
    • J.C. Erickson, A.K. Sewell, L.T. Jensen, D.R. Winge, and R.D. Palmiter Enhanced neurotrophic activity in Alzheimer's disease cortex is not associated with down-regulation of metallothionein-III (GIF) Brain Res. 649 1994 297 304
    • (1994) Brain Res. , vol.649 , pp. 297-304
    • Erickson, J.C.1    Sewell, A.K.2    Jensen, L.T.3    Winge, D.R.4    Palmiter, R.D.5
  • 10
    • 0027048685 scopus 로고
    • Molecular cloning of human growth inhibitory factor cDNA and its down-regulation in Alzheimer's disease
    • S. Tsuji, H. Kobayashi, Y. Uchida, Y. Ihara, and T. Miyatake Molecular cloning of human growth inhibitory factor cDNA and its down-regulation in Alzheimer's disease EMBO J. 11 1992 4843 4850
    • (1992) EMBO J. , vol.11 , pp. 4843-4850
    • Tsuji, S.1    Kobayashi, H.2    Uchida, Y.3    Ihara, Y.4    Miyatake, T.5
  • 11
    • 0025768860 scopus 로고
    • The growth inhibitory factor that is deficient in the Alzheimer's disease brain is a 68 amino acid metallothionein-like protein
    • Y. Uchida, K. Takio, K. Titani, Y. Ihara, and M. Yomonaga The growth inhibitory factor that is deficient in the Alzheimer's disease brain is a 68 amino acid metallothionein-like protein Neuron 7 1991 337 347
    • (1991) Neuron , vol.7 , pp. 337-347
    • Uchida, Y.1    Takio, K.2    Titani, K.3    Ihara, Y.4    Yomonaga, M.5
  • 12
    • 0030574080 scopus 로고    scopus 로고
    • Subcellular localization of growth inhibitory factor in rat brain: Light and electron microscopic immunohistochemical studies
    • M. Yamada, S. Hayashi, I. Hozumi, T. Inuzuka, S. Tsuji, and H. Takahashi Subcellular localization of growth inhibitory factor in rat brain: light and electron microscopic immunohistochemical studies Brain Res. 735 1996 257 264
    • (1996) Brain Res. , vol.735 , pp. 257-264
    • Yamada, M.1    Hayashi, S.2    Hozumi, I.3    Inuzuka, T.4    Tsuji, S.5    Takahashi, H.6
  • 16
    • 0025314685 scopus 로고
    • Role of oxygen free radicals in carcinogenesis and brain ischemia
    • R.A. Floyd Role of oxygen free radicals in carcinogenesis and brain ischemia FASEB J. 4 1990 2587 2597
    • (1990) FASEB J. , vol.4 , pp. 2587-2597
    • Floyd, R.A.1
  • 18
    • 18144406539 scopus 로고    scopus 로고
    • Oxidative stress and inflammation in Parkinson's disease: Is there a causal link?
    • A. Hald, and J. Lotharius Oxidative stress and inflammation in Parkinson's disease: is there a causal link? Exp. Neurol. 193 2005 279 290
    • (2005) Exp. Neurol. , vol.193 , pp. 279-290
    • Hald, A.1    Lotharius, J.2
  • 19
    • 0035890197 scopus 로고    scopus 로고
    • Dynamics of intracellular calcium and free radical production during ischemia in pyramidal neurons
    • M.V. Frantseva, P.L. Carlen, and J.L. Perez Velazquez Dynamics of intracellular calcium and free radical production during ischemia in pyramidal neurons Free Radic. Biol. Med. 31 2001 1216 1227
    • (2001) Free Radic. Biol. Med. , vol.31 , pp. 1216-1227
    • Frantseva, M.V.1    Carlen, P.L.2    Perez Velazquez, J.L.3
  • 20
    • 0035890209 scopus 로고    scopus 로고
    • Free radical spin trap alpha-phenyl-N-tert-butyl-nitron inhibits caspase-3 activation and reduces brain damage following a severe forebrain ischemic injury
    • P.S. Li, Q.P. He, L. Nakamura, and K. Csiszar Free radical spin trap alpha-phenyl-N-tert-butyl-nitron inhibits caspase-3 activation and reduces brain damage following a severe forebrain ischemic injury Free Radic. Biol. Med. 31 2001 1191 1197
    • (2001) Free Radic. Biol. Med. , vol.31 , pp. 1191-1197
    • Li, P.S.1    He, Q.P.2    Nakamura, L.3    Csiszar, K.4
  • 29
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding
    • M.A. Bradford A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding Anal. Biochem. 72 1976 248 254
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.A.1
  • 31
    • 3042770613 scopus 로고    scopus 로고
    • Oral administration of Crataegus flavonoids protects against ischemia/reperfusion brain damage in gerbils
    • D.L. Zhang, Y.T. Zhang, J.J. Yin, and B.L. Zhao Oral administration of Crataegus flavonoids protects against ischemia/reperfusion brain damage in gerbils J. Neurochem. 90 2004 211 219
    • (2004) J. Neurochem. , vol.90 , pp. 211-219
    • Zhang, D.L.1    Zhang, Y.T.2    Yin, J.J.3    Zhao, B.L.4
  • 32
    • 0037200013 scopus 로고    scopus 로고
    • Growth inhibitory factor prevent neurite extension and the death of cortical neurons caused by high oxygen exposure through hydroxyl radical scavenging
    • Y. Uchida, F. Gomi, T. Masumizu, and Y. Miura Growth inhibitory factor prevent neurite extension and the death of cortical neurons caused by high oxygen exposure through hydroxyl radical scavenging J. Biol. Chem. 277 2002 32353 32359
    • (2002) J. Biol. Chem. , vol.277 , pp. 32353-32359
    • Uchida, Y.1    Gomi, F.2    Masumizu, T.3    Miura, Y.4
  • 33
    • 51049095124 scopus 로고    scopus 로고
    • Metallothionein-III protects against 6-hydroxydopamine-induced oxidative stress by increasing expression of heme oxygenase-1 in a PI3K and ERK/Nrf2-dependent manner
    • Y.P. Hwang, H.G. Kim, E.H. Han, and H.G. Jeong Metallothionein-III protects against 6-hydroxydopamine-induced oxidative stress by increasing expression of heme oxygenase-1 in a PI3K and ERK/Nrf2-dependent manner Toxicol. Appl. Pharmacol. 231 2008 318 327
    • (2008) Toxicol. Appl. Pharmacol. , vol.231 , pp. 318-327
    • Hwang, Y.P.1    Kim, H.G.2    Han, E.H.3    Jeong, H.G.4
  • 34
    • 42649106170 scopus 로고    scopus 로고
    • The possible biological role of metallothionein in apoptosis
    • M. Dutsch-Wicherek, J. Sikora, and R. Tomaszewska The possible biological role of metallothionein in apoptosis Front. Biosci. 13 2008 4029 4038
    • (2008) Front. Biosci. , vol.13 , pp. 4029-4038
    • Dutsch-Wicherek, M.1    Sikora, J.2    Tomaszewska, R.3
  • 35
    • 48849086702 scopus 로고    scopus 로고
    • Metallothionein suppresses angiotensin II-induced nicotinamide adenine dinucleotide phosphate oxidase activation, nitrosative stress, apoptosis, and pathological remodeling in the diabetic heart
    • G. Zhou, X. Li, D.W. Hein, X. Xiang, J.P. Marshall, S.D. Prabhu, and L. Cai Metallothionein suppresses angiotensin II-induced nicotinamide adenine dinucleotide phosphate oxidase activation, nitrosative stress, apoptosis, and pathological remodeling in the diabetic heart J. Am. Coll. Cardiol. 52 2008 655 666
    • (2008) J. Am. Coll. Cardiol. , vol.52 , pp. 655-666
    • Zhou, G.1    Li, X.2    Hein, D.W.3    Xiang, X.4    Marshall, J.P.5    Prabhu, S.D.6    Cai, L.7
  • 36
    • 0031016825 scopus 로고    scopus 로고
    • Disruption of the metallothionein-III gene in mice: Analysis of brain zinc, behavior, and neuron vulnerability to metals, aging, and seizures
    • J.C. Erickson, G. Hollopeter, S.A. Thomas, G.J. Froelick, and R.D. Palmiter Disruption of the metallothionein-III gene in mice: analysis of brain zinc, behavior, and neuron vulnerability to metals, aging, and seizures J. Neurosci. 17 1997 1271 1281
    • (1997) J. Neurosci. , vol.17 , pp. 1271-1281
    • Erickson, J.C.1    Hollopeter, G.2    Thomas, S.A.3    Froelick, G.J.4    Palmiter, R.D.5
  • 37
    • 32244434439 scopus 로고    scopus 로고
    • Growth inhibitory factor (GIF) can protect from brain damage due to stab wounds in rat brain
    • I. Hozumi, Y. Uchida, K. Watabe, T. Sakamoto, and T. Inuzuka Growth inhibitory factor (GIF) can protect from brain damage due to stab wounds in rat brain Neurosci. Lett. 395 2006 220 223
    • (2006) Neurosci. Lett. , vol.395 , pp. 220-223
    • Hozumi, I.1    Uchida, Y.2    Watabe, K.3    Sakamoto, T.4    Inuzuka, T.5
  • 38
    • 33846239386 scopus 로고    scopus 로고
    • BETA2/NeuroD protein transduction requires cell surface heparan sulfate proteoglycans
    • H. Noguchi, H. Ueda, S. Matsumoto, N. Kobayashi, and S. Hayashi BETA2/NeuroD protein transduction requires cell surface heparan sulfate proteoglycans Hum. Gene Ther. 18 2007 10 17
    • (2007) Hum. Gene Ther. , vol.18 , pp. 10-17
    • Noguchi, H.1    Ueda, H.2    Matsumoto, S.3    Kobayashi, N.4    Hayashi, S.5
  • 39
    • 0032885987 scopus 로고    scopus 로고
    • Iron and activated oxygen species in biology: The basic chemistry
    • J.L. Pierre, and M. Fontecave Iron and activated oxygen species in biology: the basic chemistry Biometals 12 1999 195 199
    • (1999) Biometals , vol.12 , pp. 195-199
    • Pierre, J.L.1    Fontecave, M.2
  • 41
    • 0037134925 scopus 로고    scopus 로고
    • Overexpression of human metallothionein-III prevents hydrogen peroxide-induced oxidative stress in human fibroblast
    • H.J. You, K.J. Lee, and H.G. Jeong Overexpression of human metallothionein-III prevents hydrogen peroxide-induced oxidative stress in human fibroblast FEBS Lett. 521 2002 175 179
    • (2002) FEBS Lett. , vol.521 , pp. 175-179
    • You, H.J.1    Lee, K.J.2    Jeong, H.G.3
  • 42
    • 0035149749 scopus 로고    scopus 로고
    • Reactive oxygen radicals in signaling and damage in the ischemic brain
    • P.H. Chan Reactive oxygen radicals in signaling and damage in the ischemic brain J. Cereb. Blood Flow Metab. 21 2001 2 14
    • (2001) J. Cereb. Blood Flow Metab. , vol.21 , pp. 2-14
    • Chan, P.H.1
  • 43
    • 0030222364 scopus 로고    scopus 로고
    • Attenuation of rat ischemic brain damage by aged garlic extracts: A possible protecting mechanism as antioxidants
    • Y. Numagami, S. Sato, and S.T. Ohnishi Attenuation of rat ischemic brain damage by aged garlic extracts: a possible protecting mechanism as antioxidants Neurochem. Int. 29 1996 135 143
    • (1996) Neurochem. Int. , vol.29 , pp. 135-143
    • Numagami, Y.1    Sato, S.2    Ohnishi, S.T.3
  • 45
  • 46
    • 0035876483 scopus 로고    scopus 로고
    • BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak
    • W.X. Zong, T. Lindsten, A.J. Ross, G.R. MacGregor, and C.B. Thompson BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak Genes Dev. 15 2001 1481 1486
    • (2001) Genes Dev. , vol.15 , pp. 1481-1486
    • Zong, W.X.1    Lindsten, T.2    Ross, A.J.3    MacGregor, G.R.4    Thompson, C.B.5
  • 47
    • 0032575752 scopus 로고    scopus 로고
    • Mitochondria and apoptosis
    • D.R. Green, and J.C. Reed Mitochondria and apoptosis Sci. 281 1998 1309-0312
    • (1998) Sci. , vol.281 , pp. 1309-0312
    • Green, D.R.1    Reed, J.C.2
  • 50
    • 35048858737 scopus 로고    scopus 로고
    • Acacetin-induced apoptosis of human breast cancer MCF-7 cells involves caspase cascade, mitochondria-mediated death signaling and SAPK/JNK1/2-c-Jun activation
    • H.Y. Shim, J.H. Park, H.D. Paik, and S.Y. Nah Acacetin-induced apoptosis of human breast cancer MCF-7 cells involves caspase cascade, mitochondria-mediated death signaling and SAPK/JNK1/2-c-Jun activation Mol. Cells 24 2007 95 104
    • (2007) Mol. Cells , vol.24 , pp. 95-104
    • Shim, H.Y.1    Park, J.H.2    Paik, H.D.3    Nah, S.Y.4
  • 51
    • 74949085429 scopus 로고    scopus 로고
    • Metallothionin-III provides neuronal protection through activation of nuclear factor-kB via the TrkA/Phosphatidylinositol-3 kinase/Akt signaling pathway
    • H.G. Kim, Y.P. Hwang, E.H. Han, C.Y. Choi, C.Y. Yeo, J.Y. Kim, K.Y. Lee, and H.G. Jeong Metallothionin-III provides neuronal protection through activation of nuclear factor-kB via the TrkA/Phosphatidylinositol-3 kinase/Akt signaling pathway Toxicol. Sci. 112 2009 435 449
    • (2009) Toxicol. Sci. , vol.112 , pp. 435-449
    • Kim, H.G.1    Hwang, Y.P.2    Han, E.H.3    Choi, C.Y.4    Yeo, C.Y.5    Kim, J.Y.6    Lee, K.Y.7    Jeong, H.G.8
  • 52
    • 0344394903 scopus 로고    scopus 로고
    • Zinc released from metallothionin-III may contribute to hippocampal CA1 and thalamic neuronal death following acute brain injury
    • J.Y. Lee, J.H. Kim, R.D. Palmiter, and J.Y. Koh Zinc released from metallothionin-III may contribute to hippocampal CA1 and thalamic neuronal death following acute brain injury Exp. Neurol. 184 2003 337 347
    • (2003) Exp. Neurol. , vol.184 , pp. 337-347
    • Lee, J.Y.1    Kim, J.H.2    Palmiter, R.D.3    Koh, J.Y.4
  • 54
    • 77949885837 scopus 로고    scopus 로고
    • Cell-penetrating peptide technology to deliver chaperones and associated factors in diseases and basic research
    • G.P. Dietz Cell-penetrating peptide technology to deliver chaperones and associated factors in diseases and basic research Curr. Pharm. Biotechnol. 11 2010 167 174
    • (2010) Curr. Pharm. Biotechnol. , vol.11 , pp. 167-174
    • Dietz, G.P.1
  • 55
    • 0033520487 scopus 로고    scopus 로고
    • In vivo protein transduction: Delivery of a biologically active protein into the mouse
    • S.R. Schwarze, A. Ho, A. Vocero-Akbani, and S.F. Dowdy In vivo protein transduction: delivery of a biologically active protein into the mouse Sci. 285 1999 1569 1572
    • (1999) Sci. , vol.285 , pp. 1569-1572
    • Schwarze, S.R.1    Ho, A.2    Vocero-Akbani, A.3    Dowdy, S.F.4
  • 56
    • 0027398089 scopus 로고
    • Selective vulnerability and early progression of hippocampal CA1 pyrimidal cell degeneration and GFAP-positive astrocyte reactivity in the rat four-vessel occlusion model of transient global ischemia
    • J.M. Ordy, T.M. Wengenack, P. Bialobok, P.D. Coleman, P. Rodier, R.B. Baggs, W.P. Dunlap, and B. Kates Selective vulnerability and early progression of hippocampal CA1 pyrimidal cell degeneration and GFAP-positive astrocyte reactivity in the rat four-vessel occlusion model of transient global ischemia Exp. Neurol. 119 1993 128 139
    • (1993) Exp. Neurol. , vol.119 , pp. 128-139
    • Ordy, J.M.1    Wengenack, T.M.2    Bialobok, P.3    Coleman, P.D.4    Rodier, P.5    Baggs, R.B.6    Dunlap, W.P.7    Kates, B.8
  • 57
    • 0028939689 scopus 로고
    • The clinical-pathogenic mechanisms of hippocampal neuron loss and surgical outcomes in temporal lobe epilepsy
    • G.W. Mathern, T.L. Babb, B.G. Vickrey, M. Melendez, and J.K. Pretorius The clinical-pathogenic mechanisms of hippocampal neuron loss and surgical outcomes in temporal lobe epilepsy Brain 118 1995 105 118
    • (1995) Brain , vol.118 , pp. 105-118
    • Mathern, G.W.1    Babb, T.L.2    Vickrey, B.G.3    Melendez, M.4    Pretorius, J.K.5
  • 60
    • 79957639509 scopus 로고    scopus 로고
    • P2X7 receptor activation ameliorates CA3 neuronal damage via a tumor necrosis factor-α-mediated pathway in the rat hippocampus following status epilepticus
    • J.E. Kim, H.J. Ryu, and T.C. Kang P2X7 receptor activation ameliorates CA3 neuronal damage via a tumor necrosis factor-α-mediated pathway in the rat hippocampus following status epilepticus J. Neuroinflammation 8 2011 62
    • (2011) J. Neuroinflammation , vol.8 , pp. 62
    • Kim, J.E.1    Ryu, H.J.2    Kang, T.C.3
  • 61
    • 79957913261 scopus 로고    scopus 로고
    • ReLA/P65-serine 536 nuclear factor-kappa B phosphorylation is related to vulnerability to status epilepticus in the rat hippocampus
    • H.J. Ryu, J.E. Kim, S.I. Yeo, M.J. Kim, S.M. Jo, and T.C. Kang ReLA/P65-serine 536 nuclear factor-kappa B phosphorylation is related to vulnerability to status epilepticus in the rat hippocampus Neurosci. 187 2011 93 102
    • (2011) Neurosci. , vol.187 , pp. 93-102
    • Ryu, H.J.1    Kim, J.E.2    Yeo, S.I.3    Kim, M.J.4    Jo, S.M.5    Kang, T.C.6


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