Transduced PEP-1-FK506BP ameliorates atopic dermatitis in NC/Nga mice

Journal of Investigative Dermatology

Volumn 131, Issue 7, 2011, Pages 1477-1485

  Kim, So Young ^a   Sohn, Eun Jeong ^a   Kim, Dae Won ^a   Jeong, Hoon Jae ^a   Kim, Mi Jin ^a   Kang, Hye Won ^a   Shin, Min Jea ^a   Ahn, Eun Hee ^a   Kwon, Soon Won ^a   Kim, Young Nam ^a   Kwon, Hyung Joo ^a   Kim, Tae Yoon ^b   Lee, Kil Soo ^a   Park, Jinseu ^a   Eum, Won Sik ^a   Choi, Soo Young ^a  

^a Hallym University   (South Korea)

^b The Catholic University of Korea   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

1 FLUORO 2,4 DINITROBENZENE; COMPLEMENTARY DNA; GAMMA INTERFERON; HYBRID PROTEIN; I KAPPA B; I KAPPA B ALPHA; IMMUNOGLOBULIN E; INTERLEUKIN 4; INTERLEUKIN 5; MACROPHAGE DERIVED CHEMOKINE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PEPTIDE PEP 1 TACROLIMUS BINDING PROTEIN FUSION PROTEIN; SKIN PROTECTIVE AGENT; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; THYMUS AND ACTIVATION REGULATED CHEMOKINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATOPIC DERMATITIS; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVATION; EPIDERMIS HYPERPLASIA; EXPERIMENTAL MOUSE; EXPRESSION VECTOR; FEMALE; FLOW CYTOMETRY; FLUORESCENCE ANALYSIS; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOGLOBULIN BLOOD LEVEL; IN VITRO GENE TRANSFER; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SKIN BIOPSY; SKIN PROTECTION; WESTERN BLOTTING;

EID: 79958814815     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2011.49     Document Type: Article

References (50)

1. Abramovits W (2005) Atopic dermatitis. J Am Acad Dermatol 53:S86-93 (Pubitemid 40828185)
2. Allam JP, Bieber T, Novak N (2005) Recent highlights in the pathophysiology of atopic eczema. Int Arch Allergy Immunol 136:191-7 (Pubitemid 40463245)
3. An JJ, Lee YP, Kim SY et al. 2008 Transduced human PEP-1-heat shock protein 27 efficiently protects against brain ischemic insult. FEBS J 275 1296-308 (Pubitemid 351342224)
4. Barnes PJ, Karin M (1997) Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases. N Engl J Med 336:1066-71 (Pubitemid 27163860)
5. Beltrani VS (2005) Suggestions regarding a more appropriate understanding of atopic dermatitis. Curr Opin Allergy Clin Immunol 5:413-8 (Pubitemid 41345309)
6. Boguniewica M, Leung DY (2006) Atopic dermatitis. J Allergy Clin Immunol 117:S475-80
7. Bradford MA (1976) A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-54
8. Cameron AM, Nucifora FC Jr, Fung ET et al. (1997) FKBP12 binds the inositol 1,4,5-triphosphate receptor at leucine-proline (1400-1401) and anchors calcineurin to this FK506-like domain. J Biol Chem 272:27582-8 (Pubitemid 27473550)
9. Choi HS, An JJ, Kim SY et al. (2006) PEP-1-SOD fusion protein efficiently protects against paraquat-induced dopaminergic neuron damage in a Parkinson disease mouse model. Free Radic Biol Med 41:1058-68 (Pubitemid 44331570)
10. Dhar A, Young MR, Colburn NH (2002) The role of AP-1, NF-kappaB and ROS/NOS in skin carcinogenesis: the JB6 model is predictive. Mol Cell Biochem 234:185-93 (Pubitemid 34777856)
11. De Vry CG, Valdez M, Lazarov M et al. (2005) Topical application of a novel immunomodulatory peptide, RDP58, reduces skin inflammation in the phorbol ester-induced dermatitis model. J Invest Dermatol 125:473-81
12. Eum WS, Kim DW, Hwang IK et al. (2004) In vivo protein transduction: biologically active intact PEP-1-superoxide dismutase fusion protein efficiently protects against ischemic insult. Free Radic Biol Med 37:1656-69
13. Gao XK, Nakamura N, Fuseda K et al. (2004) Establishment of allergic dermatitis in NC/Nga mice as a model for severe atopic dermatitis. Biol Pharm Bull 27:1376-81 (Pubitemid 41701678)
14. Guo X, Dillman JF, Dawwon VL et al. (2001) Neuroimmune-philins novel neuroprotective and neuroregenerative targets. Ann Neurol 50:6-16
15. Harrar Y, Bellini C, Faure JD (2001) FKBPs: at the crossroads of folding and transduction. Trends Plant Sci 6:426-31 (Pubitemid 33145940)
16. Homey B, Steinhoff M, Ruzicka T et al. (2006) Cytokines and chemokines orchestrate atopic skin inflammation. J Allergy Clin Immunol 118:178-89 (Pubitemid 43946487)
17. Imai T, Baba M, Nishimura M (1997) The T cell-directed CC chemokine TARC is a highly specific biological ligand for CC chemokine receptor 4. J Biol Chem 272:15036-42 (Pubitemid 27251781)
18. Kawasaki S, Takizawa H, Yoneyama H et al. (2001) Intervention of thymus and activation-regulated chemokine attenuates the development of allergic airway inflammation and hyperresponsiveness in mice. J Immunol 166:2055-62 (Pubitemid 32114695)
19. Lee JC, Laydon JT, McDonnel PC et al. (1994) A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 372:739-46
20. Leung DY, Boguniewicz M, Howell MD et al. (2004) New insights into atopic dermatitis. J Clin Invest 113:651-7 (Pubitemid 38544154)
21. Matsuda H, Watanabe N, Geba GP et al. (1997) Development of atopic dermatitis-like skin lesions with IgE hyperproduction in NC/Nga mice. Int Immunol 9:461-6 (Pubitemid 27113270)
22. Matsuoka H, Maki N, Yoshida S et al. (2003) A mouse model of the atopic eczema/dermatitis syndrome by repeated application of a crude extract of house-dust mite Dermatophagoides farina. Allergy 58:139-45 (Pubitemid 36359833)
23. Morris MC, Depollier J, Mery J et al. (2001) A peptide carrier for the delivery of biologically active proteins into mammalian cells. Nat Biotechnol 19:1173-6 (Pubitemid 33115705)
24. Murakawa M, Yamaoka K, Tanaka Y et al. (2006) Involvement of tumor necrosis factor (TNF)-alpha in phorbol ester 12-O-tetradecanoylphorbol-13- acetate (TPA)-induced skin edema in mice. Biochem Pharmacol 71:1331-6
25. Nare B, Allocco JJ, Kuningas R et al. (1999) Development of a scintillation proximity assay for histone deacetylase using a biotinylated peptide derived from histone-H4. Anal Biochem 267:390-6 (Pubitemid 29095888)
26. Novak N, Bieber T (2003) Allergic and nonallergic forms of atopic diseases. J Allergy Clin Immunol 112:252-62 (Pubitemid 36981361)
27. Oshio T, Sasaki Y, Funakoshi-Tago M et al. (2009) Dermatophagoides farinae extract induces severe atopic dermatitis in NC/Nga mice, which is effectively suppressed by the administration of tacrolimus ointment. Int Immunopharmacol 9:403-11
28. Park J, Ryu J, Kim KA et al. (2002) Mutational analysis of a human immunodeficiency virus type 1 Tat protein transduction domain which is required for delivery of an exogenous protein into mammalian cells. J Gen Virol 83:1173-81 (Pubitemid 34477291)
29. Richard JP, Melikov K, Vives E et al. (2003) Cell-permeable peptides: a reevaluation of the mechanism of cellular uptake. J Biol Chem 278:585-90 (Pubitemid 36043612)
30. Sandoval-Lopez G, Teran LM (2001) TARC: novel mediator of allergic inflammation. Clin Exp Allergy 31:1809-12 (Pubitemid 34014725)
31. Sasakawa T, Higashi Y, Sakuma S et al. (2001) Atopic dermatitis-like skin lesions induced by topical application of mite antigens in NC/Nga mice. Int Arch Allergy Immunol 126:239-47 (Pubitemid 34042832)
32. Schiene-Fischer C, Yu C (2001) Receptor accessory folding helper enzymes: the functional role of peptidyl prolyl cis/trans isomerase. FEBS Lett 495:1-6 (Pubitemid 32367963)
33. Schultz-Larsen F, Hanifin JM (2002) Epidemiology of atopic dermatitis. Immunol Allergy Clin North Am 22:1-24 (Pubitemid 34137417)
34. Schreiber SL (1991) Chemistry and biology of the immunophilins and their immunosuppressive ligands. Science 251:283-7 (Pubitemid 21916873)
35. Scoter NA (1989) Morphology of atopic eczema. Allergy 44:16-9
36. Snyder SH, Sabatini DM (1995) Immunophilins and the nervous system. Nat Med 1:32-7
37. Song HY, Lee JA, Ju SM et al. (2008) Topical transduction of superoxide dismutase mediated by HIV-1 Tat protein transduction domain ameliorates 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice. Biochem Pharmacol 75:1348-57
38. Tanaka A, Muto S, Jung K et al. (2007) Topical application with a new NF-kB inhibitor improves atopic dermatitis in NC/NgaTnd mice. J Invest Dermatol 127:855-63 (Pubitemid 46434644)
39. Tomimori Y, Tanaka Y, Goto M et al. (2004) Repeated topical challenge with chemical antigen elicits sustained dermatitis in NC/Nga mice in specific-pathogen-free condition. J Invest Dermatol 124:119-24 (Pubitemid 40100959)
40. Tokura Y (2010) Extrinsic and intrinsic types of atopic dermatitis. J Dermatol Sci 58:1-7
41. Uehara M, Izukura R, Sawai T (1990) Blood eosinophilia in atopic dermatitis. Clin Exp Dermatol 15:264-6 (Pubitemid 20241265)
42. Verma IM, Stevenson JK, Schwarz EM et al. (1995) Rel/NF-kappaB/I kappaB family: intimate tales of association and dissociation. Genes Dev 9:2723-35 (Pubitemid 3009952)
43. Vestergaard C, Yoneyama H, Matsushima K (2000) The NC/Nga mouse: a model for atopic dermatitis. Mol Med Today 6:209-10 (Pubitemid 30252640)
44. Vestergaard C, Yoneyama H, Murai M et al. (1999) Overproduction of Th2-specific chemokines in NC/Nga mice exhibiting atopic dermatitis-like lesions. J Clin Invest 104:1097-105 (Pubitemid 29536320)
45. Wadia J, Dowdy SF (2002) Protein transduction technology. Curr Opin Biotechnol 13:52-6 (Pubitemid 34146548)
46. Watanabe N, Tomimori Y, Saito K et al. (2002) Chymase inhibitor improves dermatitis in NC/Nga mice. Int Arch Allergy Immunol 128:229-34 (Pubitemid 34765229)
47. Williams H, Robertson C, Stewart A et al. (1999) Worldwide variations in the prevalence of symptoms of atopic eczema in the international study of asthma and allergies in childhood. J Allergy Clin Immunol 103:125-38 (Pubitemid 29063202)
48. Wollenberg A, Kraft S, Oppel T, Bieber T (2000) Atopic dermatitis: pathogenetic mechanisms. Clin Exp Dermatol 25:530-4 (Pubitemid 32104618)
49. Yamada N, Wakugawa M, Kuwata S et al. (1995) Chronologic analysis of in situ cytokine expression in mite allergen-induced dermatitis in atopic subjects. J Allergy Clin Immunol 96:1069-75 (Pubitemid 26012146)
50. 2 production by asiatic acid via NF-kB inactivation in raw 264.7 macrophages: possible involvement of the IKK and MAPK pathways. Int Immunopharmacol 8:431-41