Carbonyl stress and NMDA receptor activation contribute to methylglyoxal neurotoxicity

Free Radical Biology and Medicine

Volumn 40, Issue 5, 2006, Pages 779-790

  Garcia De Arriba, Susana ^a,b   Krügel, Ute ^a   Regenthal, Ralf ^a   Vissiennon, Zacharie ^c   Verdaguer, Esther ^a,d   Lewerenz, Anne ^c   García Jordá, Elvira ^d   Pallas, Mercé ^d   Camins, Antoni ^d   Münch, Gerald ^b   Nieber, Karen ^c   Allgaier, Clemens ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b Neuroimmunological Cell Biology Unit   (Germany)

^c Institute of Pharmacy   (Germany)

^d UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Carbonyl stress; Free radicals; Methylglyoxal; Mitochondria; Neurodegeneration; NMDA receptors

Indexed keywords

ADENOSINE TRIPHOSPHATE; CARBONYL DERIVATIVE; GLUTAMIC ACID; METHYLGLYOXAL; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; N(G) NITROARGININE METHYL ESTER; REACTIVE OXYGEN METABOLITE; RHODAMINE 123; SCAVENGER;

ANIMAL TISSUE; ARTICLE; CELL LINE; CELL MEMBRANE; CELL VIABILITY; CONTROLLED STUDY; EXCITOTOXICITY; FLUORESCENCE; HUMAN; HUMAN CELL; LONG TERM EXPOSURE; MALE; MEMBRANE DEPOLARIZATION; NEUROBLASTOMA CELL; NEUROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT;

ADENOSINE TRIPHOSPHATE; BIOLOGICAL TRANSPORT; CELL LINE, TUMOR; CELL MEMBRANE; GLUTAMIC ACID; HUMANS; MEMBRANE POTENTIALS; MITOCHONDRIA; NEURONS; PYRUVALDEHYDE; REACTIVE OXYGEN SPECIES; RECEPTORS, N-METHYL-D-ASPARTATE; RHODAMINE 123;

ANIMALIA;

EID: 33644652500     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2005.09.038     Document Type: Article

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