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Volumn 48, Issue 12, 2013, Pages 1839-1847

Soft-sensor assisted dynamic investigation of mixed feed bioprocesses

Author keywords

Bioprocess technology; Dynamic experiments; In line Fourier transformation infrared spectroscopy; Mixed feed; Physiological process control; Soft sensors

Indexed keywords

BIOPROCESSES; DYNAMIC EXPERIMENT; FOURIER TRANSFORMATIONS; PHYSIOLOGICAL PROCESS; SOFT SENSORS;

EID: 84888201692     PISSN: 13595113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.procbio.2013.09.018     Document Type: Article
Times cited : (18)

References (36)
  • 1
    • 80053584838 scopus 로고    scopus 로고
    • The effect of glycerol mixed substrate on the heterologous production of a Rhizopus oryzae lipase in Pichia pastoris system
    • C. Arnau, C. Casas, and F. Valero The effect of glycerol mixed substrate on the heterologous production of a Rhizopus oryzae lipase in Pichia pastoris system Biochem Eng J 57 2011 30 37
    • (2011) Biochem Eng J , vol.57 , pp. 30-37
    • Arnau, C.1    Casas, C.2    Valero, F.3
  • 2
    • 0035921173 scopus 로고    scopus 로고
    • Analysis of single-chain antibody production in Pichia pastoris using on-line methanol control in fed-batch and mixed-feed fermentations
    • S. Hellwig, F. Emde, N.P. Raven, M. Henke, P. Van Der Logt, and R. Fischer Analysis of single-chain antibody production in Pichia pastoris using on-line methanol control in fed-batch and mixed-feed fermentations Biotechnol Bioeng 74 2001 344 352
    • (2001) Biotechnol Bioeng , vol.74 , pp. 344-352
    • Hellwig, S.1    Emde, F.2    Raven, N.P.3    Henke, M.4    Van Der Logt, P.5    Fischer, R.6
  • 3
    • 33847375437 scopus 로고    scopus 로고
    • Mixed feeds of glycerol and methanol can improve the performance of Pichia pastoris cultures: A quantitative study based on concentration gradients in transient continuous cultures
    • C. Jungo, I. Marison, and U. Von Stockar Mixed feeds of glycerol and methanol can improve the performance of Pichia pastoris cultures: a quantitative study based on concentration gradients in transient continuous cultures J Biotechnol 128 2007 824 837
    • (2007) J Biotechnol , vol.128 , pp. 824-837
    • Jungo, C.1    Marison, I.2    Von Stockar, U.3
  • 4
    • 84862219036 scopus 로고    scopus 로고
    • A dynamic fed batch strategy for a Pichia pastoris mixed feed system to increase process understanding
    • D. Zalai, C. Dietzsch, C. Herwig, and O. Spadiut A dynamic fed batch strategy for a Pichia pastoris mixed feed system to increase process understanding Biotechnol Prog 28 2012 878 886
    • (2012) Biotechnol Prog , vol.28 , pp. 878-886
    • Zalai, D.1    Dietzsch, C.2    Herwig, C.3    Spadiut, O.4
  • 5
    • 0141908157 scopus 로고    scopus 로고
    • Tuning the transcription rate of recombinant protein in strong Escherichia coli expression systems through repressor titration
    • G. Striedner, M. Cserjan-Puschmann, F. Potschacher, and K. Bayer Tuning the transcription rate of recombinant protein in strong Escherichia coli expression systems through repressor titration Biotechnol Prog 19 2003 1427 1432
    • (2003) Biotechnol Prog , vol.19 , pp. 1427-1432
    • Striedner, G.1    Cserjan-Puschmann, M.2    Potschacher, F.3    Bayer, K.4
  • 6
    • 0030009792 scopus 로고    scopus 로고
    • Kinetics of the simultaneous utilization of sugar mixtures by Escherichia coli in continuous culture
    • U. Lendenmann, M. Snozzi, and T. Egli Kinetics of the simultaneous utilization of sugar mixtures by Escherichia coli in continuous culture Appl Environ Microbiol 62 1996 1493 1499
    • (1996) Appl Environ Microbiol , vol.62 , pp. 1493-1499
    • Lendenmann, U.1    Snozzi, M.2    Egli, T.3
  • 7
    • 0020480331 scopus 로고
    • Strategies of mixed substrate utilization in microorganisms [and Discussion]
    • W. Harder, L. Dijkhuizen, and J.R. Postgate Strategies of mixed substrate utilization in microorganisms [and Discussion] Phil Trans R Soc Lond B 297 1982 459 480
    • (1982) Phil Trans R Soc Lond B , vol.297 , pp. 459-480
    • Harder, W.1    Dijkhuizen, L.2    Postgate, J.R.3
  • 8
    • 0013924571 scopus 로고
    • Effects of inhibition and repression on the utilization of substrates by heterogeneous bacterial communities
    • E. Stumm-Zollinger Effects of inhibition and repression on the utilization of substrates by heterogeneous bacterial communities Appl Microbiol 14 1966 654 664
    • (1966) Appl Microbiol , vol.14 , pp. 654-664
    • Stumm-Zollinger, E.1
  • 9
    • 0035726455 scopus 로고    scopus 로고
    • A small metabolic flux model to identify transient metabolic regulations in Saccharomyces cerevisiae
    • C. Herwig, and U. Von Stockar A small metabolic flux model to identify transient metabolic regulations in Saccharomyces cerevisiae Bioprocess Biosyst Eng 24 2002 395 403
    • (2002) Bioprocess Biosyst Eng , vol.24 , pp. 395-403
    • Herwig, C.1    Von Stockar, U.2
  • 10
    • 34447292394 scopus 로고    scopus 로고
    • A quantitative analysis of the benefits of mixed feeds of sorbitol and methanol for the production of recombinant avidin with Pichia pastoris
    • C. Jungo, J. Schenk, M. Pasquier, I.W. Marison, and U. Von Stockar A quantitative analysis of the benefits of mixed feeds of sorbitol and methanol for the production of recombinant avidin with Pichia pastoris J Biotechnol 131 2007 57 66
    • (2007) J Biotechnol , vol.131 , pp. 57-66
    • Jungo, C.1    Schenk, J.2    Pasquier, M.3    Marison, I.W.4    Von Stockar, U.5
  • 11
    • 84872383961 scopus 로고    scopus 로고
    • Dynamic process conditions in bioprocess development
    • O. Spadiut, S. Rittmann, C. Dietzsch, and C. Herwig Dynamic process conditions in bioprocess development Eng Life Sci 13 2013 88 101
    • (2013) Eng Life Sci , vol.13 , pp. 88-101
    • Spadiut, O.1    Rittmann, S.2    Dietzsch, C.3    Herwig, C.4
  • 12
    • 84877803588 scopus 로고    scopus 로고
    • Soft-sensor assisted dynamic bioprocess control: Efficient tools for bioprocess development
    • P. Sagmeister, P. Wechselberger, M. Jazini, A. Meitz, and T. Langemann Soft-sensor assisted dynamic bioprocess control: efficient tools for bioprocess development Chem Eng Sci 96 2013 190 198
    • (2013) Chem Eng Sci , vol.96 , pp. 190-198
    • Sagmeister, P.1    Wechselberger, P.2    Jazini, M.3    Meitz, A.4    Langemann, T.5
  • 13
    • 2642607890 scopus 로고    scopus 로고
    • Identification and control of oxidative metabolism in Saccharomyces cerevisiae during transient growth using calorimetric measurements
    • P. Duboc, L.G. Cascão Pereira, and U. von Stockar Identification and control of oxidative metabolism in Saccharomyces cerevisiae during transient growth using calorimetric measurements Biotechnol Bioeng 57 1998 610 619
    • (1998) Biotechnol Bioeng , vol.57 , pp. 610-619
    • Duboc, P.1    Cascão Pereira, L.G.2    Stockar, U.V.3
  • 14
    • 0037143810 scopus 로고    scopus 로고
    • The response of GS-NS0 myeloma cells to single and multiple pH perturbations
    • J.J. Osman, J. Birch, and J. Varley The response of GS-NS0 myeloma cells to single and multiple pH perturbations Biotechnol Bioeng 79 2002 398 407
    • (2002) Biotechnol Bioeng , vol.79 , pp. 398-407
    • Osman, J.J.1    Birch, J.2    Varley, J.3
  • 15
    • 77957345665 scopus 로고    scopus 로고
    • PAT method to gather bioprocess parameters in real-time using simple input variables and first principle relationships
    • P. Wechselberger, A. Seifert, and C. Herwig PAT method to gather bioprocess parameters in real-time using simple input variables and first principle relationships Chem Eng Sci 65 2010 5734 5746
    • (2010) Chem Eng Sci , vol.65 , pp. 5734-5746
    • Wechselberger, P.1    Seifert, A.2    Herwig, C.3
  • 16
    • 80054905919 scopus 로고    scopus 로고
    • A fast approach to determine a fed batch feeding profile for recombinant Pichia pastoris strains
    • C. Dietzsch, O. Spadiut, and C. Herwig A fast approach to determine a fed batch feeding profile for recombinant Pichia pastoris strains Microb Cell Fact 10 2011 85
    • (2011) Microb Cell Fact , vol.10 , pp. 85
    • Dietzsch, C.1    Spadiut, O.2    Herwig, C.3
  • 18
    • 0037955821 scopus 로고    scopus 로고
    • Generally applicable fed-batch culture concept based on the detection of metabolic state by on-line balancing
    • A.M. Jobé, C. Herwig, M. Surzyn, B. Walker, I. Marison, and U. Von Stockar Generally applicable fed-batch culture concept based on the detection of metabolic state by on-line balancing Biotechnol Bioeng 82 2003 627 639
    • (2003) Biotechnol Bioeng , vol.82 , pp. 627-639
    • Jobé, A.M.1    Herwig, C.2    Surzyn, M.3    Walker, B.4    Marison, I.5    Von Stockar, U.6
  • 19
    • 0028764687 scopus 로고
    • Linear constraint relations in biochemical reaction systems: I. Classification of the calculability and the balanceability of conversion rates
    • R.T.J.M. Van der Heijden, J.J. Heijnen, C. Hellinga, B. Romein, and K.C.A.M. Luyben Linear constraint relations in biochemical reaction systems: I. Classification of the calculability and the balanceability of conversion rates Biotechnol Bioeng 43 1994 3 10
    • (1994) Biotechnol Bioeng , vol.43 , pp. 3-10
    • Van Der Heijden, R.T.J.M.1    Heijnen, J.J.2    Hellinga, C.3    Romein, B.4    Luyben, K.C.A.M.5
  • 20
    • 84883751965 scopus 로고    scopus 로고
    • Real-time estimation of biomass and specific growth rate in physiologically variable recombinant fed-batch processes
    • P. Wechselberger, P. Sagmeister, and C. Herwig Real-time estimation of biomass and specific growth rate in physiologically variable recombinant fed-batch processes Bioprocess Biosyst Eng 36 2013 1205 1218
    • (2013) Bioprocess Biosyst Eng , vol.36 , pp. 1205-1218
    • Wechselberger, P.1    Sagmeister, P.2    Herwig, C.3
  • 21
    • 66149183267 scopus 로고    scopus 로고
    • Data reconciliation of concentration estimates from mid-infrared and dielectric spectral measurements for improved on-line monitoring of bioprocesses
    • M. Dabros, M. Amrhein, D. Bonvin, I.W. Marison, and U. Von Stockar Data reconciliation of concentration estimates from mid-infrared and dielectric spectral measurements for improved on-line monitoring of bioprocesses Biotechnol Prog 25 2009 578 588
    • (2009) Biotechnol Prog , vol.25 , pp. 578-588
    • Dabros, M.1    Amrhein, M.2    Bonvin, D.3    Marison, I.W.4    Von Stockar, U.5
  • 22
    • 4644294349 scopus 로고    scopus 로고
    • Real-time update of calibration model for better monitoring of batch processes using spectroscopy
    • H. Kornmann, S. Valentinotti, I. Marison, and U. von Stockar Real-time update of calibration model for better monitoring of batch processes using spectroscopy Biotechnol Bioeng 87 2004 593 601
    • (2004) Biotechnol Bioeng , vol.87 , pp. 593-601
    • Kornmann, H.1    Valentinotti, S.2    Marison, I.3    Stockar, U.V.4
  • 23
    • 0015213189 scopus 로고
    • Arabinose C protein: Regulation of the arabinose operin in vitro
    • J. Greenblatt, and R. Schleif Arabinose C protein: regulation of the arabinose operin in vitro Nat New Biol 233 1971 166 170
    • (1971) Nat New Biol , vol.233 , pp. 166-170
    • Greenblatt, J.1    Schleif, R.2
  • 24
    • 77955132053 scopus 로고    scopus 로고
    • AraC protein, regulation of the l-arabinose operon in Escherichia coli, and the light switch mechanism of AraC action
    • R. Schleif AraC protein, regulation of the l-arabinose operon in Escherichia coli, and the light switch mechanism of AraC action FEMS Microbiol Rev 34 2010 779 796
    • (2010) FEMS Microbiol Rev , vol.34 , pp. 779-796
    • Schleif, R.1
  • 25
    • 0034564982 scopus 로고    scopus 로고
    • Regulation of the l-arabinose operon of Escherichia coli
    • R. Schleif, and N.C. St Regulation of the l-arabinose operon of Escherichia coli Trends Genet 16 2000 559 565
    • (2000) Trends Genet , vol.16 , pp. 559-565
    • Schleif, R.1    St, N.C.2
  • 26
    • 0029032444 scopus 로고
    • In vivo induction kinetics of the arabinose promoters in Escherichia coli
    • C.M. Johnson, and R.F. Schleif In vivo induction kinetics of the arabinose promoters in Escherichia coli J Bacteriol 177 1995 3438 3442
    • (1995) J Bacteriol , vol.177 , pp. 3438-3442
    • Johnson, C.M.1    Schleif, R.F.2
  • 27
    • 0037337551 scopus 로고    scopus 로고
    • AraC protein: A love-hate relationship
    • R. Schleif AraC protein: a love-hate relationship BioEssays 25 2003 274 282
    • (2003) BioEssays , vol.25 , pp. 274-282
    • Schleif, R.1
  • 28
    • 0021724699 scopus 로고
    • Upstream repression and CRP stimulation of the Escherichia coli l-arabinose operon
    • T. Hahn, T.M. Dunn, and R. Schleif Upstream repression and CRP stimulation of the Escherichia coli l-arabinose operon J Mol Biol 180 1984 61 72
    • (1984) J Mol Biol , vol.180 , pp. 61-72
    • Hahn, T.1    Dunn, T.M.2    Schleif, R.3
  • 29
    • 0021469101 scopus 로고
    • Regulation of the araC gene of Escherichia coli: Catabolite repression, autoregulation, and effect on araBAD expression
    • C.G. Miyada, L. Stoltzfus, and G. Wilcox Regulation of the araC gene of Escherichia coli: catabolite repression, autoregulation, and effect on araBAD expression Proc Natl Acad Sci U S A 81 1984 4120 4124
    • (1984) Proc Natl Acad Sci U S A , vol.81 , pp. 4120-4124
    • Miyada, C.G.1    Stoltzfus, L.2    Wilcox, G.3
  • 30
    • 0026092358 scopus 로고
    • AraC-DNA looping: Orientation and distance-dependent loop breaking by the cyclic AMP receptor protein
    • R.B. Lobell, and R.F. Schleif AraC-DNA looping: orientation and distance-dependent loop breaking by the cyclic AMP receptor protein J Mol Biol 218 1991 45 54
    • (1991) J Mol Biol , vol.218 , pp. 45-54
    • Lobell, R.B.1    Schleif, R.F.2
  • 31
    • 0033527396 scopus 로고    scopus 로고
    • Monitoring GFP-operon fusion protein expression during high cell density cultivation of Escherichia coli using an on-line optical sensor
    • M.P. DeLisa, J. Li, G. Rao, W.A. Weigand, and W.E. Bentley Monitoring GFP-operon fusion protein expression during high cell density cultivation of Escherichia coli using an on-line optical sensor Biotechnol Bioeng 65 1999 54 64
    • (1999) Biotechnol Bioeng , vol.65 , pp. 54-64
    • Delisa, M.P.1    Li, J.2    Rao, G.3    Weigand, W.A.4    Bentley, W.E.5
  • 32
    • 79952100002 scopus 로고    scopus 로고
    • A dynamic method based on the specific substrate uptake rate to set up a feeding strategy for Pichia pastoris
    • C. Dietzsch, O. Spadiut, and C. Herwig A dynamic method based on the specific substrate uptake rate to set up a feeding strategy for Pichia pastoris Microb Cell Fact 10 2011 14
    • (2011) Microb Cell Fact , vol.10 , pp. 14
    • Dietzsch, C.1    Spadiut, O.2    Herwig, C.3
  • 33
    • 84873284678 scopus 로고    scopus 로고
    • Model-based analysis on the extractability of information from data in dynamic fed-batch experiments
    • P. Wechselberger, P. Sagmeister, and C. Herwig Model-based analysis on the extractability of information from data in dynamic fed-batch experiments Biotechnol Prog 29 2013 285 296
    • (2013) Biotechnol Prog , vol.29 , pp. 285-296
    • Wechselberger, P.1    Sagmeister, P.2    Herwig, C.3
  • 34
    • 33745482610 scopus 로고    scopus 로고
    • Improvement of bioprocess monitoring: Development of novel concepts
    • F. Clementschitsch, and K. Bayer Improvement of bioprocess monitoring: development of novel concepts Microb Cell Fact 5 2006 19
    • (2006) Microb Cell Fact , vol.5 , pp. 19
    • Clementschitsch, F.1    Bayer, K.2
  • 35
    • 46949087562 scopus 로고    scopus 로고
    • Biomass measurement online: The performance of in situ measurements and software sensors
    • K. Kiviharju, K. Salonen, U. Moilanen, and T. Eerikäinen Biomass measurement online: the performance of in situ measurements and software sensors J Ind Microbiol Biotechnol 35 2008 657 665
    • (2008) J Ind Microbiol Biotechnol , vol.35 , pp. 657-665
    • Kiviharju, K.1    Salonen, K.2    Moilanen, U.3    Eerikäinen, T.4
  • 36
    • 84885354877 scopus 로고    scopus 로고
    • A dynamic method for the investigation of induced state metabolic capacities as a function of temperature
    • manuscript under revision
    • P. Sagmeister, T. Langemann, P. Wechselberger, and A. Meitz A dynamic method for the investigation of induced state metabolic capacities as a function of temperature Microb Cell Fact 2013 manuscript under revision
    • (2013) Microb Cell Fact
    • Sagmeister, P.1    Langemann, T.2    Wechselberger, P.3    Meitz, A.4


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