PAT method to gather bioprocess parameters in real-time using simple input variables and first principle relationships

Chemical Engineering Science

Volumn 65, Issue 21, 2010, Pages 5734-5746

  Wechselberger, Patrick ^a   Seifert, Arne ^a   Herwig, Christoph ^a  

^a VIENNA UNIVERSITY OF TECHNOLOGY   (Austria)

Author keywords

Bioprocessing; Mathematical modeling; Metabolism; Parameter identification; Process Analytical Technology (PAT); Quality by Design (QbD)

Indexed keywords

BIOPROCESSING; MATHEMATICAL MODELING; PARAMETER IDENTIFICATION; PROCESS ANALYTICAL TECHNOLOGY; QUALITY BY DESIGNS;

BATCH CELL CULTURE; COMPUTER SIMULATION; DESIGN; DRUG PRODUCTS PLANTS; ECOLOGY; GROWTH KINETICS; GROWTH RATE; METABOLISM; PARAMETER ESTIMATION; REAL VARIABLES; STOICHIOMETRY; YEAST;

SUBSTRATES;

EID: 77957345665     PISSN: 00092509     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ces.2010.05.002     Document Type: Article

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