Toxicogenomic outcomes predictive of forestomach carcinogenesis following exposure to benzo(a)pyrene: Relevance to human cancer risk

Toxicology and Applied Pharmacology

Volumn 273, Issue 2, 2013, Pages 269-280

  Labib, Sarah ^a   Guo, Charles H ^a   Williams, Andrew ^a   Yauk, Carole L ^a   White, Paul A ^a   Halappanavar, Sabina ^a  

^a HEALTH CANADA   (Canada)

Author keywords

Antigen processing and presentation; Cancer; Human relevance; Immunoproteasome; Microarrays; Polycyclic aromatic hydrocarbons

Indexed keywords

BENZO[A]PYRENE; PROTEASOME;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTATION; ARTICLE; CANCER RISK; CELL DIFFERENTIATION; CHEMOTAXIS; CONTROLLED STUDY; DIGESTIVE SYSTEM CANCER; DNA MICROARRAY; FORESTOMACH; FORESTOMACH CANCER; GENE EXPRESSION; IMMUNE RESPONSE; KERATINOCYTE; MALE; MOUSE; NONHUMAN; PREDICTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RISK ASSESSMENT; STOMACH CANCER; STOMACH CARCINOGENESIS; XENOBIOTIC METABOLISM;

AHR; ANTIGEN PROCESSING AND PRESENTATION; ARYL HYDROCARBON RECEPTOR; BAP; BENZO(A)PYRENE; BENZO(A)PYRENE-7,8-DIHYDRODIOL-9,10-EPOXIDE; BODY WEIGHT; BPDE; BW; CANCER; FALSE DISCOVERY RATE; FDR; GENE ONTOLOGY; GLUTATHIONE; GO; GSH; HUMAN RELEVANCE; IMMUNOPROTEASOME; MAJOR HISTOCOMPATIBILITY COMPLEX; MHC; MICROARRAYS; NATURAL KILLER T CELLS; NKT; PAH; POLYCYCLIC AROMATIC HYDROCARBON; POLYCYCLIC AROMATIC HYDROCARBONS; QUANTITATIVE REAL TIME PCR; RT-QPCR;

ANIMALS; BENZO(A)PYRENE; CARCINOGENESIS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MALE; MICE; MICE, TRANSGENIC; PREDICTIVE VALUE OF TESTS; RISK FACTORS; STOMACH NEOPLASMS; TOXICOGENETICS;

MUS; RODENTIA;

EID: 84888200643     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2013.05.027     Document Type: Article

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