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Volumn 24, Issue 1, 2012, Pages 77-83

Immunoproteasomes at the interface of innate and adaptive immune responses: Two faces of one enzyme

Author keywords

[No Author keywords available]

Indexed keywords

I PROTEASOME; IMMUNOPROTEASOME; INTERFERON; ISOENZYME; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PROTEASOME; PROTEIN; UNCLASSIFIED DRUG;

EID: 84857056178     PISSN: 09527915     EISSN: 18790372     Source Type: Journal    
DOI: 10.1016/j.coi.2012.01.005     Document Type: Review
Times cited : (77)

References (53)
  • 1
    • 0032971227 scopus 로고    scopus 로고
    • Degradation of cell proteins and the generation of MHC class I-presented peptides
    • Rock K.L., Goldberg A.L. Degradation of cell proteins and the generation of MHC class I-presented peptides. Annu Rev Immunol 1999, 17:739-779.
    • (1999) Annu Rev Immunol , vol.17 , pp. 739-779
    • Rock, K.L.1    Goldberg, A.L.2
  • 2
    • 28544435897 scopus 로고    scopus 로고
    • Immunity by ubiquitylation: a reversible process of modification
    • Liu Y.C., Penninger J., Karin M. Immunity by ubiquitylation: a reversible process of modification. Nat Rev Immunol 2005, 5:941-952.
    • (2005) Nat Rev Immunol , vol.5 , pp. 941-952
    • Liu, Y.C.1    Penninger, J.2    Karin, M.3
  • 3
    • 11244309014 scopus 로고    scopus 로고
    • Proteolysis: from the lysosome to ubiquitin and the proteasome
    • Ciechanover A. Proteolysis: from the lysosome to ubiquitin and the proteasome. Nat Rev Mol Cell Biol 2005, 6:79-87.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 79-87
    • Ciechanover, A.1
  • 5
    • 0035290730 scopus 로고    scopus 로고
    • Antigen processing by the proteasome
    • Kloetzel P.M. Antigen processing by the proteasome. Nat Rev Mol Cell Biol 2001, 2:179-187.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 179-187
    • Kloetzel, P.M.1
  • 6
    • 26244445001 scopus 로고    scopus 로고
    • Interferon-gamma, the functional plasticity of the ubiquitin-proteasome system, and MHC class I antigen processing
    • Strehl B., Seifert U., Krüger E., Heink S., Kuckelkorn U., Kloetzel P.M. Interferon-gamma, the functional plasticity of the ubiquitin-proteasome system, and MHC class I antigen processing. Immunol Rev 2005, 207:19-30.
    • (2005) Immunol Rev , vol.207 , pp. 19-30
    • Strehl, B.1    Seifert, U.2    Krüger, E.3    Heink, S.4    Kuckelkorn, U.5    Kloetzel, P.M.6
  • 10
    • 79958772781 scopus 로고    scopus 로고
    • The role of the proteasome in the generation of MHC class I ligands and immune responses
    • Sijts E.J., Kloetzel P.M. The role of the proteasome in the generation of MHC class I ligands and immune responses. Cell Mol Life Sci 2011, 68:1491-1502.
    • (2011) Cell Mol Life Sci , vol.68 , pp. 1491-1502
    • Sijts, E.J.1    Kloetzel, P.M.2
  • 11
    • 26244435436 scopus 로고    scopus 로고
    • The seven dirty little secrets of major histocompatibility complex calls I antigen processing
    • Yewdell J.W. The seven dirty little secrets of major histocompatibility complex calls I antigen processing. Immunol Rev 2005, 207:8-18.
    • (2005) Immunol Rev , vol.207 , pp. 8-18
    • Yewdell, J.W.1
  • 12
    • 23244457800 scopus 로고    scopus 로고
    • Immunoproteasome-deficient mice mount largely normal CD8+ T cell responses to lymphocytic choriomeningitis virus infection and DNA vaccination
    • Nussbaum A.K., Rodriguez-Carreno M.P., Benning N., Botten J., Whitton J.L. Immunoproteasome-deficient mice mount largely normal CD8+ T cell responses to lymphocytic choriomeningitis virus infection and DNA vaccination. J Immunol 2005, 175:1153-1160.
    • (2005) J Immunol , vol.175 , pp. 1153-1160
    • Nussbaum, A.K.1    Rodriguez-Carreno, M.P.2    Benning, N.3    Botten, J.4    Whitton, J.L.5
  • 13
    • 72949103056 scopus 로고    scopus 로고
    • Proteasomes in immune cells: more than peptide producers?
    • Groettrup M., Kirk C.J., Basler M. Proteasomes in immune cells: more than peptide producers?. Nat Rev Immunol 2010, 10:73-78.
    • (2010) Nat Rev Immunol , vol.10 , pp. 73-78
    • Groettrup, M.1    Kirk, C.J.2    Basler, M.3
  • 14
    • 21544475903 scopus 로고    scopus 로고
    • IFN-gamma-induced immune adaptation of the proteasome system is an accelerated and transient response
    • Heink S., Ludwig D., Kloetzel P.M., Kruger E. IFN-gamma-induced immune adaptation of the proteasome system is an accelerated and transient response. Proc Natl Acad Sci USA 2005, 102:9241-9246.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 9241-9246
    • Heink, S.1    Ludwig, D.2    Kloetzel, P.M.3    Kruger, E.4
  • 15
    • 59649085296 scopus 로고    scopus 로고
    • Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system
    • Ebstein F., Lange N., Urban S., Seifert U., Kruger E., Kloetzel P.M. Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system. Int J Biochem Cell Biol 2009, 41:1205-1215.
    • (2009) Int J Biochem Cell Biol , vol.41 , pp. 1205-1215
    • Ebstein, F.1    Lange, N.2    Urban, S.3    Seifert, U.4    Kruger, E.5    Kloetzel, P.M.6
  • 16
    • 0032730872 scopus 로고    scopus 로고
    • Dendritic cells up-regulate immunoproteasomes and the proteasome regulator PA28 during maturation
    • Macagno A., Gilliet M., Sallusto F., Lanzavecchia A., Nestle F.O., Groettrup M. Dendritic cells up-regulate immunoproteasomes and the proteasome regulator PA28 during maturation. Eur J Immunol 1999, 29:4037-4042.
    • (1999) Eur J Immunol , vol.29 , pp. 4037-4042
    • Macagno, A.1    Gilliet, M.2    Sallusto, F.3    Lanzavecchia, A.4    Nestle, F.O.5    Groettrup, M.6
  • 17
    • 33750597617 scopus 로고    scopus 로고
    • Virus-induced type I interferon stimulates generation of immunoproteasomes at the site of function
    • Shin E.C., Seifert U., Kato T., Rice C., Feinstone S.M., Kloetzel P.M., Rehermann B. Virus-induced type I interferon stimulates generation of immunoproteasomes at the site of function. J Clin Invest 2006, 116:3006-3014.
    • (2006) J Clin Invest , vol.116 , pp. 3006-3014
    • Shin, E.C.1    Seifert, U.2    Kato, T.3    Rice, C.4    Feinstone, S.M.5    Kloetzel, P.M.6    Rehermann, B.7
  • 18
    • 0037105392 scopus 로고    scopus 로고
    • Regulation of immunoproteasome subunit expression in vivo following pathogenic fungal infection
    • Barton L.F., Cruz M., Rangwala R., Deepe G.S., Monaco J.J. Regulation of immunoproteasome subunit expression in vivo following pathogenic fungal infection. J Immunol 2002, 169:3046-3052.
    • (2002) J Immunol , vol.169 , pp. 3046-3052
    • Barton, L.F.1    Cruz, M.2    Rangwala, R.3    Deepe, G.S.4    Monaco, J.J.5
  • 19
    • 49449116792 scopus 로고    scopus 로고
    • Oxidative innate immune defenses by Nox/Duox family NADPH oxidases
    • Rada B., Leto T.L. Oxidative innate immune defenses by Nox/Duox family NADPH oxidases. Contrib Microbiol 2008, 15:164-187.
    • (2008) Contrib Microbiol , vol.15 , pp. 164-187
    • Rada, B.1    Leto, T.L.2
  • 21
    • 73849114173 scopus 로고    scopus 로고
    • Jak/STAT signaling pathway regulates nox1 and nox4-based NADPH oxidase in human aortic smooth muscle cells
    • Manea A., Tanase L.I., Raicu M., Simionescu M. Jak/STAT signaling pathway regulates nox1 and nox4-based NADPH oxidase in human aortic smooth muscle cells. Arterioscler Thromb Vasc Biol 2010, 30:105-112.
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , pp. 105-112
    • Manea, A.1    Tanase, L.I.2    Raicu, M.3    Simionescu, M.4
  • 22
    • 0037333837 scopus 로고    scopus 로고
    • An oxidative mechanism of interferon induced priming of the Fas pathway in Fanconi anemia cells
    • Pearl-Yafe M., Halperin D., Halevy A., Kalir H., Bielora B., Fabian I. An oxidative mechanism of interferon induced priming of the Fas pathway in Fanconi anemia cells. Biochem Pharmacol 2003, 65:833-842.
    • (2003) Biochem Pharmacol , vol.65 , pp. 833-842
    • Pearl-Yafe, M.1    Halperin, D.2    Halevy, A.3    Kalir, H.4    Bielora, B.5    Fabian, I.6
  • 23
    • 48449088578 scopus 로고    scopus 로고
    • Proinflammatory cytokine-induced cellular senescence of biliary epithelial cells is mediated via oxidative stress and activation of ATM pathway: a culture study
    • Sasaki M., Ikeda H., Sato Y., Nakanuma Y. Proinflammatory cytokine-induced cellular senescence of biliary epithelial cells is mediated via oxidative stress and activation of ATM pathway: a culture study. Free Radic Res 2008, 1-8.
    • (2008) Free Radic Res , pp. 1-8
    • Sasaki, M.1    Ikeda, H.2    Sato, Y.3    Nakanuma, Y.4
  • 24
    • 47849083585 scopus 로고    scopus 로고
    • Nrf2 signaling: an adaptive response pathway for protection against environmental toxic insults
    • Osburn W.O., Kensler T.W. Nrf2 signaling: an adaptive response pathway for protection against environmental toxic insults. Mutat Res 2008, 659:31-39.
    • (2008) Mutat Res , vol.659 , pp. 31-39
    • Osburn, W.O.1    Kensler, T.W.2
  • 26
    • 79952139698 scopus 로고    scopus 로고
    • Nrf2-mediated induction of p62 controls Toll-like receptor-4-driven aggresome-like induced structure formation and autophagic degradation
    • Fujita K., Maeda D., Xiao Q., Srinivasula S.M. Nrf2-mediated induction of p62 controls Toll-like receptor-4-driven aggresome-like induced structure formation and autophagic degradation. Proc Natl Acad Sci USA 2011, 108:1427-1432.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 1427-1432
    • Fujita, K.1    Maeda, D.2    Xiao, Q.3    Srinivasula, S.M.4
  • 27
    • 79954511326 scopus 로고    scopus 로고
    • Redox control of the ubiquitin-proteasome system: from molecular mechanisms to functional significance
    • Kriegenburg F., Poulsen E.G., Koch A., Kruger E., Hartmann-Petersen R. Redox control of the ubiquitin-proteasome system: from molecular mechanisms to functional significance. Antioxid Redox Signal 2011, 15:2265-2299.
    • (2011) Antioxid Redox Signal , vol.15 , pp. 2265-2299
    • Kriegenburg, F.1    Poulsen, E.G.2    Koch, A.3    Kruger, E.4    Hartmann-Petersen, R.5
  • 28
    • 0031573667 scopus 로고    scopus 로고
    • Proteasome activity limits the assembly of MHC class I molecules after IFN-gamma stimulation
    • Benham A., Neefjes J. Proteasome activity limits the assembly of MHC class I molecules after IFN-gamma stimulation. J Immunol 1997, 159:5896-5904.
    • (1997) J Immunol , vol.159 , pp. 5896-5904
    • Benham, A.1    Neefjes, J.2
  • 32
    • 0034643336 scopus 로고    scopus 로고
    • Rapid degradation of a large fraction of newly synthesized proteins by proteasomes
    • Schubert U., Antón L.C., Gibbs J., Norbury C.C., Yewdell J.W., Bennink J.R. Rapid degradation of a large fraction of newly synthesized proteins by proteasomes. Nature 2000, 404:770-774.
    • (2000) Nature , vol.404 , pp. 770-774
    • Schubert, U.1    Antón, L.C.2    Gibbs, J.3    Norbury, C.C.4    Yewdell, J.W.5    Bennink, J.R.6
  • 33
    • 0034643348 scopus 로고    scopus 로고
    • The major substrates for TAP in vivo are derived from newly synthesized proteins
    • Reits E.A., Vos J.C., Grommé M., Neefjes J. The major substrates for TAP in vivo are derived from newly synthesized proteins. Nature 2000, 404:774-778.
    • (2000) Nature , vol.404 , pp. 774-778
    • Reits, E.A.1    Vos, J.C.2    Grommé, M.3    Neefjes, J.4
  • 34
    • 77954008149 scopus 로고    scopus 로고
    • Targeting the proteasome: partial inhibition of the proteasome by bortezomib or deletion of the immunosubunit LMP7 attenuates experimental colitis
    • Schmidt N., Gonzalez E., Visekruna A., Kuhl A.A., Loddenkemper C., Mollenkopf H., Kaufmann S.H., Steinhoff U., Joeris T. Targeting the proteasome: partial inhibition of the proteasome by bortezomib or deletion of the immunosubunit LMP7 attenuates experimental colitis. Gut 2010, 59:896-906.
    • (2010) Gut , vol.59 , pp. 896-906
    • Schmidt, N.1    Gonzalez, E.2    Visekruna, A.3    Kuhl, A.A.4    Loddenkemper, C.5    Mollenkopf, H.6    Kaufmann, S.H.7    Steinhoff, U.8    Joeris, T.9
  • 35
    • 0000181420 scopus 로고    scopus 로고
    • Reply to 'LMP2 expression and proteasome activity in NOD mice'
    • Hayashi T., Kodama S., Faustman D.L. Reply to 'LMP2 expression and proteasome activity in NOD mice'. Nat Med 2000, 6:1065-1066.
    • (2000) Nat Med , vol.6 , pp. 1065-1066
    • Hayashi, T.1    Kodama, S.2    Faustman, D.L.3
  • 41
    • 80052679971 scopus 로고    scopus 로고
    • Proteasome immunosubunits protect against the development of CD8 T cell-mediated autoimmune diseases
    • Zaiss D.M., Bekker C.P., Grone A., Lie B.A., Sijts A.J. Proteasome immunosubunits protect against the development of CD8 T cell-mediated autoimmune diseases. J Immunol 2011, 187:2302-2309.
    • (2011) J Immunol , vol.187 , pp. 2302-2309
    • Zaiss, D.M.1    Bekker, C.P.2    Grone, A.3    Lie, B.A.4    Sijts, A.J.5
  • 42
    • 0034614889 scopus 로고    scopus 로고
    • Efficient generation of a hepatitis B virus cytotoxic T lymphocyte epitope requires the structural features of immunoproteasomes
    • Sijts A.J., Ruppert T., Rehermann B., Schmidt M., Koszinowski U., Kloetzel P.M. Efficient generation of a hepatitis B virus cytotoxic T lymphocyte epitope requires the structural features of immunoproteasomes. J Exp Med 2000, 191:503-514.
    • (2000) J Exp Med , vol.191 , pp. 503-514
    • Sijts, A.J.1    Ruppert, T.2    Rehermann, B.3    Schmidt, M.4    Koszinowski, U.5    Kloetzel, P.M.6
  • 43
    • 33845399734 scopus 로고    scopus 로고
    • Heat shock up-regulates lmp2 and lmp7 and enhances presentation of immunoproteasome-dependent epitopes
    • Callahan M.K., Wohlfert E.A., Menoret A., Srivastava P.K. Heat shock up-regulates lmp2 and lmp7 and enhances presentation of immunoproteasome-dependent epitopes. J Immunol 2006, 177:8393-8399.
    • (2006) J Immunol , vol.177 , pp. 8393-8399
    • Callahan, M.K.1    Wohlfert, E.A.2    Menoret, A.3    Srivastava, P.K.4
  • 44
    • 4143146486 scopus 로고    scopus 로고
    • Inhibition of apoptosis in acute promyelocytic leukemia cells leads to increases in levels of oxidized protein and LMP2 immunoproteasome
    • Khan M.A., Oubrahim H., Stadtman E.R. Inhibition of apoptosis in acute promyelocytic leukemia cells leads to increases in levels of oxidized protein and LMP2 immunoproteasome. Proc Natl Acad Sci USA 2004, 101:11560-11565.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 11560-11565
    • Khan, M.A.1    Oubrahim, H.2    Stadtman, E.R.3
  • 45
    • 21144441198 scopus 로고    scopus 로고
    • Systems analysis of transcriptome and proteome in retinoic acid/arsenic trioxide-induced cell differentiation/apoptosis of promyelocytic leukemia
    • Zheng P.Z., Wang K.K., Zhang Q.Y., Huang Q.H., Du Y.Z., Zhang Q.H., Xiao D.K., Shen S.H., Imbeaud S., Eveno E., et al. Systems analysis of transcriptome and proteome in retinoic acid/arsenic trioxide-induced cell differentiation/apoptosis of promyelocytic leukemia. Proc Natl Acad Sci USA 2005, 102:7653-7658.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 7653-7658
    • Zheng, P.Z.1    Wang, K.K.2    Zhang, Q.Y.3    Huang, Q.H.4    Du, Y.Z.5    Zhang, Q.H.6    Xiao, D.K.7    Shen, S.H.8    Imbeaud, S.9    Eveno, E.10
  • 47
    • 27744601821 scopus 로고    scopus 로고
    • Non-neuronal induction of immunoproteasome subunits in an ALS model: possible mediation by cytokines
    • Puttaparthi K., Elliott J.L. Non-neuronal induction of immunoproteasome subunits in an ALS model: possible mediation by cytokines. Exp Neurol 2005, 196:441-451.
    • (2005) Exp Neurol , vol.196 , pp. 441-451
    • Puttaparthi, K.1    Elliott, J.L.2
  • 49
    • 1042265187 scopus 로고    scopus 로고
    • Neuropathology and pathogenesis of encephalitis following amyloid-beta immunization in Alzheimer's disease
    • Ferrer I., Boada Rovira M., Sanchez Guerra M.L., Rey M.J., Costa-Jussa F. Neuropathology and pathogenesis of encephalitis following amyloid-beta immunization in Alzheimer's disease. Brain Pathol 2004, 14:11-20.
    • (2004) Brain Pathol , vol.14 , pp. 11-20
    • Ferrer, I.1    Boada Rovira, M.2    Sanchez Guerra, M.L.3    Rey, M.J.4    Costa-Jussa, F.5
  • 50
    • 33646053214 scopus 로고    scopus 로고
    • T cells lacking immunoproteasome subunits MECL-1 and LMP7 hyperproliferate in response to polyclonal mitogens
    • Caudill C.M., Jayarapu K., Elenich L., Monaco J.J., Colbert R.A., Griffin T.A. T cells lacking immunoproteasome subunits MECL-1 and LMP7 hyperproliferate in response to polyclonal mitogens. J Immunol 2006, 176:4075-4082.
    • (2006) J Immunol , vol.176 , pp. 4075-4082
    • Caudill, C.M.1    Jayarapu, K.2    Elenich, L.3    Monaco, J.J.4    Colbert, R.A.5    Griffin, T.A.6
  • 51
    • 67650388103 scopus 로고    scopus 로고
    • A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis
    • Muchamuel T., Basler M., Aujay M.A., Suzuki E., Kalim K.W., Lauer C., Sylvain C., Ring E.R., Shields J., Jiang J., et al. A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis. Nat Med 2009, 15:781-787.
    • (2009) Nat Med , vol.15 , pp. 781-787
    • Muchamuel, T.1    Basler, M.2    Aujay, M.A.3    Suzuki, E.4    Kalim, K.W.5    Lauer, C.6    Sylvain, C.7    Ring, E.R.8    Shields, J.9    Jiang, J.10
  • 52
    • 78649558302 scopus 로고    scopus 로고
    • Immunoproteasomes are essential for survival and expansion of T cells in virus-infected mice
    • Moebius J., van den Broek M., Groettrup M., Basler M. Immunoproteasomes are essential for survival and expansion of T cells in virus-infected mice. Eur J Immunol 2010, 40:3439-3449.
    • (2010) Eur J Immunol , vol.40 , pp. 3439-3449
    • Moebius, J.1    van den Broek, M.2    Groettrup, M.3    Basler, M.4
  • 53
    • 77956198116 scopus 로고    scopus 로고
    • Prevention of experimental colitis by a selective inhibitor of the immunoproteasome
    • Basler M., Dajee M., Moll C., Groettrup M., Kirk C.J. Prevention of experimental colitis by a selective inhibitor of the immunoproteasome. J Immunol 2010, 185:634-641.
    • (2010) J Immunol , vol.185 , pp. 634-641
    • Basler, M.1    Dajee, M.2    Moll, C.3    Groettrup, M.4    Kirk, C.J.5


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