Mode-of-action framework for evaluating the relevance of rodent forestomach tumors in cancer risk assessment

Toxicological Sciences

Volumn 98, Issue 2, 2007, Pages 313-326

  Proctor, Deborah M ^a   Gatto, Nicole M ^a   Hong, Sandra J ^a   Allamneni, Krishna P ^a,b  

^a EXPONENT INC   (United States)

^b GENENTECH INC   (United States)

Author keywords

Cancer risk assessment; Forestomach tumors; Mode of action

Indexed keywords

1,2 DIBROMOETHANE; 1,3 BUTADIENE; ACRYLIC ACID DERIVATIVE; ACRYLONITRILE; ALLYL CHLORIDE; BENZO[A]PYRENE; CARCINOGEN; DICHLORVOS; EPICHLOROHYDRIN; MERCURIC CHLORIDE; METHYLNITROSOUREA; PROPYLENE; PROPYLENE OXIDE; VINYL CHLORIDE;

BIOASSAY; CANCER CELL; CANCER GROWTH; CANCER LOCALIZATION; CANCER RESEARCH; CANCER RISK; CARCINOGENESIS; CARCINOGENICITY; CELL PROLIFERATION; CHEMICAL ANALYSIS; CLINICAL PRACTICE; COMPARATIVE ANATOMY; CONCENTRATION (PARAMETERS); FORESTOMACH; GENOTOXICITY; GOVERNMENT REGULATION; HISTOPATHOLOGY; HUMAN; MEDICAL RESEARCH; NONHUMAN; PATHOLOGICAL ANATOMY; PREDICTION; QUANTITATIVE ANALYSIS; REVIEW; RISK ASSESSMENT; RISK FACTOR; RODENT; STANDARDIZATION; STOMACH TUMOR; TISSUE SPECIFICITY; TOXICOKINETICS; TOXIN ANALYSIS;

ANIMALS; CARCINOGENS; ENVIRONMENTAL EXPOSURE; GASTROINTESTINAL NEOPLASMS; HUMANS; MICE; RATS; RISK ASSESSMENT; SPECIES SPECIFICITY;

ANIMALIA; RODENTIA;

EID: 34547851676     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfm075     Document Type: Review

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