Transcriptomic fingerprints in human peripheral blood mononuclear cells indicative of genotoxic and non-genotoxic carcinogenic exposure

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 746, Issue 2, 2012, Pages 124-134

  Hochstenbach, K ^a   Van Leeuwen, D M ^a   Gottschalk, R W ^a   Gmuender, H ^b   Stolevik S B ^c   Nygaard, U C ^c   Lovik M ^c,d   Granum, B ^c   Namork, E ^c   Van Loveren, H ^a,e   Van Delft, J H M ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b GENEDATA AG   (Switzerland)

^c NORWEGIAN INSTITUTE OF PUBLIC HEALTH   (Norway)

^d NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

^e NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

Author keywords

Biomarker; Genotoxicity; Human; Non genotoxic carcinogenicity; Peripheral blood mononuclear cells; Transcriptomics

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 4 HYDROXYNONENAL; ACRYLAMIDE; ACTIN; ADENOSINE DIPHOSPHATE RIBOSYLATION FACTOR 6; AFLATOXIN B1; ALCOHOL; ANDROGEN RECEPTOR; BENZO[A]PYRENE; BIOLOGICAL MARKER; CARCINOGEN; CD147 ANTIGEN; CD68 ANTIGEN; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DIMETHYLNITROSAMINE; HAMARTIN; MALONALDEHYDE; MYC PROTEIN; POLYCHLORINATED BIPHENYL; PRDM5 PROTEIN; PROTEIN P53; STAT1 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ESR1; TRANSCRIPTION FACTOR SP1; TRANSCRIPTOME; UNCLASSIFIED DRUG; XERODERMA PIGMENTOSUM GROUP C PROTEIN;

ARTICLE; CELL PROLIFERATION; CYTOTOXICITY; FEMALE; GENE EXPRESSION; GENOTOXICITY; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; MICROARRAY ANALYSIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL;

BIOLOGICAL MARKERS; CARCINOGENS; GENE EXPRESSION PROFILING; HUMANS; LEUKOCYTES, MONONUCLEAR; MUTAGENS; SIGNAL TRANSDUCTION; TRANSCRIPTOME; TUMOR MARKERS, BIOLOGICAL;

EID: 84861579335     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2012.01.002     Document Type: Article

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