Computational evaluation of cellular metabolic costssuccessfully predicts genes whose expression is deleterious

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 47, 2013, Pages 19166-19171

  Wagner, Allon ^a   Zarecki, Raphy ^a   Reshef, Leah ^a   Gochev, Camelia ^a   Sorek, Rotem ^b   Gophna, Uri ^a,c   Ruppin, Eytan ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^c NATIONAL EVOLUTIONARY SYNTHESIS CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CANCER GENETICS; CELL METABOLISM; COMPUTER MODEL; GENE DELETION; GENE OVEREXPRESSION; GENE REPRESSION; NONHUMAN; PRIORITY JOURNAL; RECEPTOR UPREGULATION;

CONSTRAINT-BASED MODELING; FLUX BALANCE ANALYSIS; HORIZONTAL GENE TRANSFER; METABOLIC MODELING; SYSTEMS METABOLIC ENGINEERING;

ALGORITHMS; COMPUTATIONAL BIOLOGY; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; METABOLIC NETWORKS AND PATHWAYS; MODELS, GENETIC;

EID: 84888122057     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1312361110     Document Type: Article

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