Evidence that the fosfomycin-producing epoxidase, HppE, is a non-heme-iron peroxidase

Science

Volumn 342, Issue 6161, 2013, Pages 991-995

  Wang, Chen ^a   Chang, Wei Chen ^a   Guo, Yisong ^a   Huang, Hui ^b   Peck, Spencer C ^c   Pandelia, Maria E ^a   Lin, Geng Min ^b   Liu, Hung Wen ^b   Krebs, Carsten ^a   Bollinger, J Martin ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXYPROPYL 1 PHOSPHONATE EPOXIDASE; CATALASE; FOSFOMYCIN; HEME; HYDROGEN PEROXIDE; IRON; OXIDOREDUCTASE; PEROXIDASE; UNCLASSIFIED DRUG; 2-HYDROXYPROPYLPHOSPHONIC ACID EPOXIDASE; ANTIINFECTIVE AGENT; NONHEME IRON PROTEIN;

ENZYME; IRON; STOICHIOMETRY; SUBSTRATE;

ARTICLE; COMPLEX FORMATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME MECHANISM; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; EPOXIDATION; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STOICHIOMETRY; STREPTOMYCES; BIOSYNTHESIS; CHEMISTRY; CLASSIFICATION; ENZYMOLOGY; YERSINIA PSEUDOTUBERCULOSIS;

ANTI-BACTERIAL AGENTS; FOSFOMYCIN; HYDROGEN PEROXIDE; NONHEME IRON PROTEINS; OXIDOREDUCTASES; PEROXIDASES; YERSINIA PSEUDOTUBERCULOSIS;

EID: 84888026754     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1240373     Document Type: Article

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