메뉴 건너뛰기




Volumn 5, Issue 17, 2013, Pages 2103-2116

Use of zebrafish in chemical biology and drug discovery

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; CYCLOOXYGENASE 2 INHIBITOR; ESTRADIOL DERIVATIVE; GLYCOGEN SYNTHASE KINASE 3BETA; HEME OXYGENASE 1; HONOKIOL; ISOINDOLE DERIVATIVE; PYRAZOLOPYRIMIDINE DERIVATIVE; RETINOIC ACID; RIBOSOME PROTEIN; THALIDOMIDE; TRIAZINE;

EID: 84887968332     PISSN: 17568919     EISSN: 17568927     Source Type: Journal    
DOI: 10.4155/fmc.13.170     Document Type: Review
Times cited : (24)

References (67)
  • 1
    • 0019452034 scopus 로고
    • Production of clones of homozygous diploid zebra fish (Brachydanio rerio)
    • DOI 10.1038/291293a0
    • Streisinger G, Walker C, Dower N., Knauber D, Singer F. Production of clones of homozygous diploid zebrafish (Brachydanio rerio). Nature 291(5813), 293-296 (1981). (Pubitemid 11083423)
    • (1981) Nature , vol.291 , Issue.5813 , pp. 293-296
    • Streisinger, G.1    Walker, C.2    Dower, N.3
  • 2
    • 84867842154 scopus 로고    scopus 로고
    • The zebrafish issue of development
    • Nüsslein-Volhard C. The zebrafish issue of development. Development 139(22), 4099-4103 (2012).
    • (2012) Development , vol.139 , Issue.22 , pp. 4099-4103
    • Nüsslein-Volhard, C.1
  • 3
    • 0035704743 scopus 로고    scopus 로고
    • Generating transparent zebrafish: A refined method to improve detection of gene expression during embryonic development
    • Karlsson J, Von Hofsten J, Olsson PE Generating transparent zebrafish: a refined method to improve detection of gene expression during embryonic development. Mar. Biotechnol. (NY) 3(6), 522-527 (2001). (Pubitemid 34115368)
    • (2001) Marine Biotechnology , vol.3 , Issue.6 , pp. 522-527
    • Karlsson, J.1    Von Hofsten, J.2    Olsson, P.-E.3
  • 4
    • 13444272394 scopus 로고    scopus 로고
    • Zebrafish as a pharmacological tool: The how, why and when
    • DOI 10.1016/j.coph.2004.04.005, PII S1471489204001183
    • Goldsmith P. Zebrafish as a pharmacological tool: the how, why and when. Curr. Opin. Pharmacol. 4(5), 504-512 (2004) (Pubitemid 40533012)
    • (2004) Current Opinion in Pharmacology , vol.4 , Issue.5 , pp. 504-512
    • Goldsmith, P.1
  • 5
    • 0142167588 scopus 로고    scopus 로고
    • Zebrafish-Based small molecule discovery
    • DOI 10.1016/j.chembiol.2003.10.003
    • MacRae CA, Peterson RT Zebrafish-based small molecule discovery. Chem. Biol. 10(10), 901-908 (2003). (Pubitemid 37316907)
    • (2003) Chemistry and Biology , vol.10 , Issue.10 , pp. 901-908
    • MacRae, C.A.1    Peterson, R.T.2
  • 6
    • 84860389672 scopus 로고    scopus 로고
    • The zebrafish: A powerful platform for in vivo, HTS drug discovery
    • Delvecchio C, Tiefenbach J, Krause HM The zebrafish: a powerful platform for in vivo, HTS drug discovery. Assay Drug Dev. Technol. 9(4), 354-361 (2011).
    • (2011) Assay Drug Dev. Technol. , vol.9 , Issue.4 , pp. 354-361
    • Delvecchio, C.1    Tiefenbach, J.2    Krause, H.M.3
  • 7
    • 12144273121 scopus 로고    scopus 로고
    • In vivo drug discovery in the zebrafish
    • DOI 10.1038/nrd1606
    • Zon LI, Peterson RT in vivo drug discovery in the zebrafish. Nat. Rev. Drug Discov. 4(1), 35-44 (2005). (Pubitemid 40109588)
    • (2005) Nature Reviews Drug Discovery , vol.4 , Issue.1 , pp. 35-44
    • Zon, L.I.1    Peterson, R.T.2
  • 8
    • 13344283336 scopus 로고    scopus 로고
    • Discovery of therapeutic targets by phenotype-based zebrafish screens
    • DOI 10.1016/j.ddtec.2004.07.002, PII S1740674904000083
    • Peterson RT. Discovery of therapeutic targets by phenotype-based zebrafish screens. Drug Discov. Today Technol. 1(1), 49-54 (2004). (Pubitemid 40197552)
    • (2004) Drug Discovery Today: Technologies , vol.1 , Issue.1 , pp. 49-54
    • Peterson, R.T.1
  • 9
    • 77953311260 scopus 로고    scopus 로고
    • Small molecule screening in zebrafish: An in vivo approach to identifying new chemical tools and drug leads
    • Taylor KL, Grant NJ, Temperley N.D., Patton EE Small molecule screening in zebrafish: an in vivo approach to identifying new chemical tools and drug leads. Cell Commun. Signal. 8, 11 (2010).
    • (2010) Cell Commun. Signal. , vol.8 , pp. 11
    • Taylor, K.L.1    Grant, N.J.2    Temperley, N.D.3    Patton, E.E.4
  • 11
    • 84867044870 scopus 로고    scopus 로고
    • Identification of phosphorylase kinase as a novel therapeutic target through high-throughput screening for anti-angiogenesis compounds in zebrafish
    • Camus S, Quevedo C, Menéndez S et al. Identification of phosphorylase kinase as a novel therapeutic target through high-throughput screening for anti-angiogenesis compounds in zebrafish. Oncogene 31(39), 4333-4342 (2012).
    • (2012) Oncogene , vol.31 , Issue.39 , pp. 4333-4342
    • Camus, S.1    Quevedo, C.2    Menéndez, S.3
  • 12
    • 77955513656 scopus 로고    scopus 로고
    • Rosuvastatin, identified from a zebrafish chemical genetic screen for antiangiogenic compounds, suppresses the growth of prostate cancer
    • Wang C, Tao W, Wang Y et al. Rosuvastatin, identified from a zebrafish chemical genetic screen for antiangiogenic compounds, suppresses the growth of prostate cancer. Eur. Urol. 58(3), 418-426 (2010).
    • (2010) Eur. Urol. , vol.58 , Issue.3 , pp. 418-426
    • Wang, C.1    Tao, W.2    Wang, Y.3
  • 14
    • 47649084257 scopus 로고    scopus 로고
    • APC mutant zebrafish uncover a changing temporal requirement for wnt signaling in liver development
    • Goessling W, North TE, Lord AM et al. APC mutant zebrafish uncover a changing temporal requirement for wnt signaling in liver development. Dev. Biol. 320(1), 161-174 (2008).
    • (2008) Dev. Biol. , vol.320 , Issue.1 , pp. 161-174
    • Goessling, W.1    North, T.E.2    Lord, A.M.3
  • 15
    • 62149148156 scopus 로고    scopus 로고
    • Genetic interaction of PGE2 and wnt signaling regulates developmental specification of stem cells and regeneration
    • Goessling W, North TE, Loewer S et al. Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration. Cell 136(6), 1136-1147 (2009).
    • (2009) Cell , vol.136 , Issue.6 , pp. 1136-1147
    • Goessling, W.1    North, T.E.2    Loewer, S.3
  • 16
    • 77949350034 scopus 로고    scopus 로고
    • Identification of a primary target of thalidomide teratogenicity
    • Ito T, Ando H, Suzuki T et al. Identification of a primary target of thalidomide teratogenicity. Science 327(5971), 1345-1350 (2010).
    • (2010) Science , vol.327 , Issue.5971 , pp. 1345-1350
    • Ito, T.1    Ando, H.2    Suzuki, T.3
  • 17
    • 51549116267 scopus 로고    scopus 로고
    • Retinoic acid synthesis and signaling during early organogenesis
    • Duester G. Retinoic acid synthesis and signaling during early organogenesis. Cell 134(6), 921-931 (2008).
    • (2008) Cell , vol.134 , Issue.6 , pp. 921-931
    • Duester, G.1
  • 18
    • 0037398609 scopus 로고    scopus 로고
    • Effects of retinoic acid on proliferation, apoptosis, cytotoxicity, migration, and invasion of neuroblastoma cells
    • DOI 10.1002/mpo.10250
    • Voigt A, Zintl F. Effects of retinoic acid on proliferation, apoptosis, cytotoxicity, migration, and invasion of neuroblastoma cells. Med. Pediatr. Oncol. 40(4), 205-213 (2003). (Pubitemid 36222824)
    • (2003) Medical and Pediatric Oncology , vol.40 , Issue.4 , pp. 205-213
    • Voigt, A.1    Zintl, F.2
  • 19
    • 77955590506 scopus 로고    scopus 로고
    • Between death and survival: Retinoic acid in regulation of apoptosis
    • Noy N. Between death and survival: retinoic acid in regulation of apoptosis. Annu. Rev. Nutr. 30, 201-217 (2010).
    • (2010) Annu. Rev. Nutr. , vol.30 , pp. 201-217
    • Noy, N.1
  • 20
    • 77956305347 scopus 로고    scopus 로고
    • A forward chemical screen in zebrafish identifies a retinoic acid derivative with receptor specificity
    • Das BC, McCartin K, Liu T.C., Peterson RT, Evans T. A forward chemical screen in zebrafish identifies a retinoic acid derivative with receptor specificity. PLoS One 5(4), e10004 (2010).
    • (2010) PLoS One , vol.5 , Issue.4
    • Das, B.C.1    McCartin, K.2    Liu, T.C.3    Peterson, R.T.4    Evans, T.5
  • 21
    • 0141737854 scopus 로고    scopus 로고
    • Bovine spongiform encephalopathy (BSE) and its epidemiology
    • DOI 10.1093/bmb/66.1.185
    • Smith PG, Bradley R. Bovine spongiform encephalopathy (BSE) and its epidemiology. Br. Med. Bull. 66, 185-198 (2003). (Pubitemid 37173502)
    • (2003) British Medical Bulletin , vol.66 , pp. 185-198
    • Smith, P.G.1    Bradley, R.2
  • 23
    • 80052959006 scopus 로고    scopus 로고
    • Discovery of 6-substituted indole-3-glyoxylamides as lead antiprion agents with enhanced cell line activity, improved microsomal stability and low toxicity
    • Thompson MJ, Louth JC, Ferrara S et al. Discovery of 6-substituted indole-3-glyoxylamides as lead antiprion agents with enhanced cell line activity, improved microsomal stability and low toxicity. Eur. J. Med. Chem. 46(9), 4125-4132 (2011).
    • (2011) Eur. J. Med. Chem. , vol.46 , Issue.9 , pp. 4125-4132
    • Thompson, M.J.1    Louth, J.C.2    Ferrara, S.3
  • 24
    • 84874943660 scopus 로고    scopus 로고
    • Structure-based optimization of oxadiazole-based GSK-3 inhibitors
    • Plotkin B, Eldar-Finkelman H, Schmidt B. Structure-based optimization of oxadiazole-based GSK-3 inhibitors. Eur. J. Med. Chem. 61, 26-40 (2013).
    • (2013) Eur. J. Med. Chem. , vol.61 , pp. 26-40
    • Plotkin, B.1    Eldar-Finkelman, H.2    Schmidt, B.3
  • 25
    • 77249094568 scopus 로고    scopus 로고
    • Benzo[e] isoindole-1,3-diones as potential inhibitors of glycogen synthase kinase-3 (GSK-3). Synthesis, kinase inhibitory activity, zebrafish phenotype, and modeling of binding mode
    • Zou H, Zhou L, Li Y et al. Benzo[e] isoindole-1,3-diones as potential inhibitors of glycogen synthase kinase-3 (GSK-3). Synthesis, kinase inhibitory activity, zebrafish phenotype, and modeling of binding mode. J. Med. Chem. 53(3), 994-1003 (2010).
    • (2010) J. Med. Chem. , vol.53 , Issue.3 , pp. 994-1003
    • Zou, H.1    Zhou, L.2    Li, Y.3
  • 26
    • 77953777757 scopus 로고    scopus 로고
    • Design and synthesis of novel xyloketal derivatives and their vasorelaxing activities in rat thoracic aorta and angiogenic activities in zebrafish angiogenesis screen
    • Xu Z, Li Y, Xiang Q et al. Design and synthesis of novel xyloketal derivatives and their vasorelaxing activities in rat thoracic aorta and angiogenic activities in zebrafish angiogenesis screen. J. Med. Chem. 53(12), 4642-4653 (2010).
    • (2010) J. Med. Chem. , vol.53 , Issue.12 , pp. 4642-4653
    • Xu, Z.1    Li, Y.2    Xiang, Q.3
  • 27
    • 84875787395 scopus 로고    scopus 로고
    • Xyloketal B exhibits its antioxidant activity through induction of HO-1 in vascular endothelial cells and zebrafish
    • Li ZX, Chen JW, Yuan F et al. Xyloketal B exhibits its antioxidant activity through induction of HO-1 in vascular endothelial cells and Zebrafish. Mar. Drugs 11(2), 504-522 (2013).
    • (2013) Mar. Drugs , vol.11 , Issue.2 , pp. 504-522
    • Li, Z.X.1    Chen, J.W.2    Yuan, F.3
  • 28
    • 61449155600 scopus 로고    scopus 로고
    • A gold(I) phosphine complex containing a naphthalimide ligand functions as a TrxR inhibiting antiproliferative agent and angiogenesis inhibitor
    • Ott I, Qian X, Xu Y et al. A gold(I) phosphine complex containing a naphthalimide ligand functions as a TrxR inhibiting antiproliferative agent and angiogenesis inhibitor. J. Med. Chem. 52(3), 763-770 (2009).
    • (2009) J. Med. Chem , vol.52 , Issue.3 , pp. 763-770
    • Ott, I.1    Qian, X.2    Xu, Y.3
  • 29
    • 84865110779 scopus 로고    scopus 로고
    • A combined targeted/phenotypic approach for the identification of new antiangiogenics agents active on a zebrafish model: From in silico screening to cyclodextrin formulation
    • Radi M, Evensen L, Dreassi E et al. A combined targeted/phenotypic approach for the identification of new antiangiogenics agents active on a zebrafish model: from in silico screening to cyclodextrin formulation. Bioorg. Med. Chem. Lett. 22(17), 5579-5583 (2012).
    • (2012) Bioorg. Med. Chem. Lett , vol.22 , Issue.17 , pp. 5579-5583
    • Radi, M.1    Evensen, L.2    Dreassi, E.3
  • 30
    • 80053917269 scopus 로고    scopus 로고
    • Structural modification of honokiol, a biphenyl occurring in magnolia officinalis: The evaluation of honokiol analogues as inhibitors of angiogenesis and for their cytotoxicity and structure-activity relationship
    • Ma L, Chen J, Wang X et al. Structural modification of honokiol, a biphenyl occurring in Magnolia officinalis: the evaluation of honokiol analogues as inhibitors of angiogenesis and for their cytotoxicity and structure-activity relationship. J. Med. Chem. 54(19), 6469-6481 (2011).
    • (2011) J. Med. Chem. , vol.54 , Issue.19 , pp. 6469-6481
    • Ma, L.1    Chen, J.2    Wang, X.3
  • 31
    • 77449108244 scopus 로고    scopus 로고
    • In vivo structure-activity relationship study of dorsomorphin analogues identifies selective VEGF and BMP inhibitors
    • Hao J, Ho JN, Lewis JA et al. in vivo structure-activity relationship study of dorsomorphin analogues identifies selective VEGF and BMP inhibitors. ACS Chem. Biol. 5(2), 245-253 (2010).
    • (2010) ACS Chem. Biol , vol.5 , Issue.2 , pp. 245-253
    • Hao, J.1    Ho, J.N.2    Lewis, J.A.3
  • 32
    • 0028220858 scopus 로고
    • The endogenous oestrogen metabolite 2-methoxyoestradiol inhibits angiogenesis and suppresses tumour growth
    • DOI 10.1038/368237a0
    • Fotsis T, Zhang Y, Pepper MS et al. The endogenous oestrogen metabolite 2-methoxyoestradiol inhibits angiogenesis and suppresses tumour growth. Nature 368(6468), 237-239 (1994). (Pubitemid 24108838)
    • (1994) Nature , vol.368 , Issue.6468 , pp. 237-239
    • Fotsis, T.1    Zhang, Y.2    Pepper, M.S.3    Adlercreutz, H.4    Montesano, R.5    Nawrotht, P.P.6    Schweigerer, L.7
  • 33
    • 84872869427 scopus 로고    scopus 로고
    • Antiangiogenic, antimigratory and antiinflammatory effects of 2-methoxyestradiol in zebrafish larvae
    • Quezada M, Alvarez M, Peña OA et al. Antiangiogenic, antimigratory and antiinflammatory effects of 2-methoxyestradiol in zebrafish larvae. Comp. Biochem. Physiol. C Toxicol. Pharmacol. 157(2), 141-149 (2013).
    • (2013) Comp. Biochem. Physiol. C Toxicol. Pharmacol. , vol.157 , Issue.2 , pp. 141-149
    • Quezada, M.1    Alvarez, M.2    Peña, O.A.3
  • 34
    • 84870248583 scopus 로고    scopus 로고
    • 2-styrylindolium based fluorescent probes visualize neurofibrillary tangles in alzheimer's disease
    • Gu J, Anumala UR, Lo Monte F et al. 2-styrylindolium based fluorescent probes visualize neurofibrillary tangles in Alzheimer's disease. Bioorg. Med. Chem. Lett. 22(24), 7667-7671 (2012).
    • (2012) Bioorg. Med. Chem. Lett. , vol.22 , Issue.24 , pp. 7667-7671
    • Gu, J.1    Anumala, U.R.2    Lo Monte, F.3
  • 35
    • 84861461646 scopus 로고    scopus 로고
    • Screening of anti-cancer agent using zebrafish: Comparison with the MTT assay
    • Li Y, Huang W, Huang S., Du J, Huang C. Screening of anti-cancer agent using zebrafish: comparison with the MTT assay. Biochem. Biophys. Res. Commun. 422(1), 85-90 (2012).
    • (2012) Biochem. Biophys. Res. Commun. , vol.422 , Issue.1 , pp. 85-90
    • Li, Y.1    Huang, W.2    Huang, S.3    Du, J.4    Huang, C.5
  • 36
    • 9644272423 scopus 로고    scopus 로고
    • The ubiquitin system: Pathogenesis of human diseases and drug targeting
    • DOI 10.1016/j.bbamcr.2004.09.018, PII S0167488904002344, The Ubiquitin-Proteasome System
    • Ciechanover A, Schwartz AL The ubiquitin system: pathogenesis of human diseases and drug targeting. Biochim. Biophys. Acta. 1695(1-3), 3-17 (2004). (Pubitemid 39574964)
    • (2004) Biochimica et Biophysica Acta - Molecular Cell Research , vol.1695 , Issue.1-3 , pp. 3-17
    • Ciechanover, A.1    Schwartz, A.L.2
  • 38
    • 34347400984 scopus 로고    scopus 로고
    • Proteasome inhibitor bortezomib-induced apoptosis in natural killer (NK) - Cell leukemia and lymphoma: An in vitro and in vivo preclinical evaluation [2]
    • DOI 10.1182/blood-2007-02-072900
    • Shen L, Au W Y, Guo T et al. Proteasome inhibitor bortezomib-induced apoptosis in natural killer (NK)-cell leukemia and lymphoma: an in vitro and in vivo preclinical evaluation. Blood 110(1), 469-470 (2007). (Pubitemid 47026871)
    • (2007) Blood , vol.110 , Issue.1 , pp. 469-470
    • Shen, L.1    Au, W.-Y.2    Guo, T.3    Wong, K.-Y.4    Wong, M.L.5    Tsuchiyama, J.6    Yuen, P.-W.7    Kwong, Y.-L.8    Liang, R.H.9    Srivastava, G.10
  • 40
    • 77949367260 scopus 로고    scopus 로고
    • Synthesis, in vitro and in vivo biological evaluation, docking studies, and structure-activity relationship (SAR) discussion of dipeptidyl boronic acid proteasome inhibitors composed of b-amino acids
    • Zhu Y, Zhu X, Wu G et al. Synthesis, in vitro and in vivo biological evaluation, docking studies, and structure-activity relationship (SAR) discussion of dipeptidyl boronic acid proteasome inhibitors composed of b-amino acids. J. Med. Chem. 53(5), 1990-1999 (2010).
    • (2010) J. Med. Chem. , vol.53 , Issue.5 , pp. 1990-1999
    • Zhu, Y.1    Zhu, X.2    Wu, G.3
  • 41
    • 70350049072 scopus 로고    scopus 로고
    • Development of a screening assay to identify teratogenic and embryotoxic chemicals using the zebrafish embryo
    • Selderslaghs I.W., Van Rompay AR, De Coen W, Witters HE Development of a screening assay to identify teratogenic and embryotoxic chemicals using the zebrafish embryo. Reprod. Toxicol. 28(3), 308-320 (2009).
    • (2009) Reprod. Toxicol. , vol.28 , Issue.3 , pp. 308-320
    • Selderslaghs, I.W.1    Van Rompay, A.R.2    De Coen, W.3    Witters, H.E.4
  • 42
    • 4444262869 scopus 로고    scopus 로고
    • Development of a respiratory burst assay using zebrafish kidneys and embryos
    • DOI 10.1016/j.jim.2004.06.016, PII S0022175904002017
    • Hermann AC, Millard PJ, Blake S.L., Kim CH Development of a respiratory burst assay using zebrafish kidneys and embryos. J. Immunol. Methods. 292(1-2),119-129 (2004). (Pubitemid 39185873)
    • (2004) Journal of Immunological Methods , vol.292 , Issue.1-2 , pp. 119-129
    • Hermann, A.C.1    Millard, P.J.2    Blake, S.L.3    Kim, C.H.4
  • 43
    • 0242474597 scopus 로고    scopus 로고
    • Analysis of Small Molecule Metabolism in Zebrafish
    • DOI 10.1016/S0076-6879(03)64023-1
    • Ho SY, Pack M, Farber SA Analysis of small molecule metabolism in zebrafish. Methods Enzymol. 364, 408-426 (2003). (Pubitemid 37408460)
    • (2003) Methods in Enzymology , vol.364 , pp. 408-426
    • Ho, S.-Y.1    Pack, M.2    Farber, S.A.3
  • 44
    • 84864401578 scopus 로고    scopus 로고
    • Visualization of lipid metabolism in the zebrafish intestine reveals a relationship between NPC1L1-mediated cholesterol uptake and dietary fatty acid
    • Walters J.W., Anderson JL, Bittman R, Pack M., Farber SA Visualization of lipid metabolism in the zebrafish intestine reveals a relationship between NPC1L1-mediated cholesterol uptake and dietary fatty acid. Chem. Biol. 19(7), 913-925 (2012).
    • (2012) Chem. Biol. , vol.19 , Issue.7 , pp. 913-925
    • Walters, J.W.1    Anderson, J.L.2    Bittman, R.3    Pack, M.4    Farber, S.A.5
  • 45
    • 84871555083 scopus 로고    scopus 로고
    • A high-throughput fluorescence-based assay system for appetite-regulating gene and drug screening
    • Shimada Y, Hirano M, Nishimura Y., Tanaka T. A high-throughput fluorescence-based assay system for appetite-regulating gene and drug screening. PLoS One 7(12), e52549 (2012).
    • (2012) PLoS One , vol.7 , Issue.12
    • Shimada, Y.1    Hirano, M.2    Nishimura, Y.3    Tanaka, T.4
  • 46
    • 78751604246 scopus 로고    scopus 로고
    • Novel chemical suppressors of long QT syndrome identified by an in vivo functional screen
    • Peal DS, Mills RW, Lynch SN et al. Novel chemical suppressors of long QT syndrome identified by an in vivo functional screen. Circulation 123(1), 23-30 (2011).
    • (2011) Circulation , vol.123 , Issue.1 , pp. 23-30
    • Peal, D.S.1    Mills, R.W.2    Lynch, S.N.3
  • 47
    • 84877746824 scopus 로고    scopus 로고
    • A novel chemical screening strategy in zebrafish identifies common pathways in embryogenesis and rhabdomyosarcoma development
    • Le X, Pugach EK, Hettmer S et al. A novel chemical screening strategy in zebrafish identifies common pathways in embryogenesis and rhabdomyosarcoma development. Development 140(11), 2354-2364 (2013).
    • (2013) Development , vol.140 , Issue.11 , pp. 2354-2364
    • Le, X.1    Pugach, E.K.2    Hettmer, S.3
  • 48
    • 84867609315 scopus 로고    scopus 로고
    • Facilitating drug discovery: An automated high-content inflammation assay in zebrafish
    • Wittmann C, Reischl M, Shah A.H., Mikut R., Liebel U, Grabher C. Facilitating drug discovery: an automated high-content inflammation assay in zebrafish. J. Vis. Exp. 65, e4203 (2012).
    • (2012) J. Vis. Exp. , vol.65
    • Wittmann, C.1    Reischl, M.2    Shah, A.H.3    Mikut, R.4    Liebel, U.5    Grabher, C.6
  • 49
    • 84872081347 scopus 로고    scopus 로고
    • In vivo monitoring of cardiomyocyte proliferation to identify chemical modifiers of heart regeneration
    • Choi W.Y., Gemberling M, Wang J et al. in vivo monitoring of cardiomyocyte proliferation to identify chemical modifiers of heart regeneration. Development 140(3), 660-666 (2013).
    • (2013) Development , vol.140 , Issue.3 , pp. 660-666
    • Choi, W.Y.1    Gemberling, M.2    Wang, J.3
  • 50
    • 84880631170 scopus 로고    scopus 로고
    • Transgenic retinoic acid sensor lines in zebrafish indicate regions of available embryonic retinoic acid
    • Mandal A, Rydeen A, Anderson J et al. Transgenic retinoic acid sensor lines in zebrafish indicate regions of available embryonic retinoic acid. Dev. Dyn. 242(8), 989-1000 (2013).
    • (2013) Dev. Dyn. , vol.242 , Issue.8 , pp. 989-1000
    • Mandal, A.1    Rydeen, A.2    Anderson, J.3
  • 51
    • 48149111146 scopus 로고    scopus 로고
    • Zebrafish: An emerging technology for in vivo pharmacological assessment to identify potential safety liabilities in early drug discovery
    • Barros TP, Alderton WK, Reynolds H.M., Roach AG, Berghmans S. Zebrafish: an emerging technology for in vivo pharmacological assessment to identify potential safety liabilities in early drug discovery. Br. J. Pharmacol. 154 (7), 1400-1413 (2008).
    • (2008) Br. J. Pharmacol. , vol.154 , Issue.7 , pp. 1400-1413
    • Barros, T.P.1    Alderton, W.K.2    Reynolds, H.M.3    Roach, A.G.4    Berghmans, S.5
  • 53
    • 77954642090 scopus 로고    scopus 로고
    • Accumulation and metabolism of drugs and CYP probe substrates in zebrafish larvae
    • Alderton W, Berghmans S, Butler P et al. Accumulation and metabolism of drugs and CYP probe substrates in zebrafish larvae. Xenobiotica 40(8), 547-557 (2010).
    • (2010) Xenobiotica , vol.40 , Issue.8 , pp. 547-557
    • Alderton, W.1    Berghmans, S.2    Butler, P.3
  • 54
    • 77949352393 scopus 로고    scopus 로고
    • 2,3,7,8-tetrachlorodibenzo-p-dioxin upregulates FoxQ1b in zebrafish jaw primordium
    • Planchart A, Mattingly CJ 2,3,7,8-tetrachlorodibenzo-p-dioxin upregulates FoxQ1b in zebrafish jaw primordium. Chem. Res. Toxicol. 23(3), 480-487 (2010).
    • (2010) Chem. Res. Toxicol , vol.23 , Issue.3 , pp. 480-487
    • Planchart, A.1    Mattingly, C.J.2
  • 55
    • 33745726634 scopus 로고    scopus 로고
    • In vivo recording of adult zebrafish electrocardiogram and assessment of drug-induced QT prolongation
    • Milan DJ, Jones IL, Ellinor P.T., MacRae CA in vivo recording of adult zebrafish electrocardiogram and assessment of drug-induced QT prolongation. Am. J. Physiol. Heart Circ. Physiol. 291(1), H269-H273 (2006).
    • (2006) Am. J. Physiol. Heart Circ. Physiol. , vol.291 , Issue.1
    • Milan, D.J.1    Jones, I.L.2    Ellinor, P.T.3    MacRae, C.A.4
  • 56
    • 84873800554 scopus 로고    scopus 로고
    • Dioxin inhibits zebrafish epicardium and proepicardium development
    • Plavicki J, Hofsteen P, Peterson R.E., Heideman W. Dioxin inhibits zebrafish epicardium and proepicardium development. Toxicol. Sci. 131(2), 558-567 (2013).
    • (2013) Toxicol. Sci , vol.131 , Issue.2 , pp. 558-567
    • Plavicki, J.1    Hofsteen, P.2    Peterson, R.E.3    Heideman, W.4
  • 57
    • 84876707193 scopus 로고    scopus 로고
    • Cardiovascular risk assessment of atypical antipsychotic drugs in a zebrafish model
    • Lee SH, Kim HR, Han R.X., Oqani RK, Jin DI Cardiovascular risk assessment of atypical antipsychotic drugs in a zebrafish model. J. Appl. Toxicol. 33(6), 466-470 (2013).
    • (2013) J. Appl. Toxicol. , vol.33 , Issue.6 , pp. 466-470
    • Lee, S.H.1    Kim, H.R.2    Han, R.X.3    Oqani, R.K.4    Jin, D.I.5
  • 58
    • 43049176656 scopus 로고    scopus 로고
    • Zebrafish: A predictive model for assessing drug-induced toxicity
    • McGrath P, Li CQ Zebrafish: a predictive model for assessing drug-induced toxicity. Drug Discov. Today 13(9-10), 394-401 (2008).
    • (2008) Drug Discov. Today , vol.13 , Issue.9-10 , pp. 394-401
    • McGrath, P.1    Li, C.Q.2
  • 60
    • 0029014231 scopus 로고
    • Teratogenic effects of retinoic acid and related substances on the early development of the zebrafish (Brachydanio rerio) as assessed by a novel scoring system
    • Herrmann K. Teratogenic effects of retinoic acid and related substances on the early development of the zebrafish (Brachydanio rerio) as assessed by a novel scoring system. Toxic. In Vitro 9(3), 267-283 (1995).
    • (1995) Toxic. in Vitro , vol.9 , Issue.3 , pp. 267-283
    • Herrmann, K.1
  • 61
    • 0033953726 scopus 로고    scopus 로고
    • The teratogenic effects of methylmercury on early development of the zebrafish, Danio rerio
    • DOI 10.1016/S0166-445X(99)00044-2, PII S0166445X99000442
    • Samson JC, Shenker J. The teratogenic effects of methylmercury on early development of the zebrafish, Danio rerio. Aquat. Toxicol. 48(2-3), 343-354 (2000). (Pubitemid 30109223)
    • (2000) Aquatic Toxicology , vol.48 , Issue.2-3 , pp. 343-354
    • Samson, J.C.1    Shenker, J.2
  • 62
    • 77950034488 scopus 로고    scopus 로고
    • Dithiocarbamates are teratogenic to developing zebrafish through inhibition of lysyl oxidase activity
    • Van Boxtel A.L., Kamstra JH, Fluitsma D.M., Legler J. Dithiocarbamates are teratogenic to developing zebrafish through inhibition of lysyl oxidase activity. Toxicol. Appl. Pharmacol. 244(2), 156-161 (2010).
    • (2010) Toxicol. Appl. Pharmacol. , vol.244 , Issue.2 , pp. 156-161
    • Van Boxtel, A.L.1    Kamstra, J.H.2    Fluitsma, D.M.3    Legler, J.4
  • 63
    • 36649016027 scopus 로고    scopus 로고
    • The teratogenic effects of polychlorinated naphthalenes (PCNs) on early development of the zebrafish (Danio rerio)
    • DOI 10.1016/j.etap.2007.09.001, PII S1382668907001159
    • Sişman T T, Geyikoǧlu F. The teratogenic effects of polychlorinated naphthalenes (PCNs) on early development of the zebrafish (Danio rerio). Environ. Toxicol. Pharmacol. 25(1), 83-88 (2008). (Pubitemid 350199005)
    • (2008) Environmental Toxicology and Pharmacology , vol.25 , Issue.1 , pp. 83-88
    • Sisman, T.1    Geyikoglu, F.2
  • 64
    • 77954352788 scopus 로고    scopus 로고
    • Visualizing extravasation dynamics of metastatic tumor cells
    • Stoletov K, Kato H, Zardouzian E et al. Visualizing extravasation dynamics of metastatic tumor cells. J. Cell Sci. 123(Pt 13), 2332-2341 (2010).
    • (2010) J. Cell Sci. , vol.123 , Issue.PART 13 , pp. 2332-2341
    • Stoletov, K.1    Kato, H.2    Zardouzian, E.3
  • 65
    • 79953056443 scopus 로고    scopus 로고
    • The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset
    • Ceol CJ, Houvras Y, Jane-Valbuena J et al. The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset. Nature 471(7339), 513-517 (2011).
    • (2011) Nature , vol.471 , Issue.7339 , pp. 513-517
    • Ceol, C.J.1    Houvras, Y.2    Jane-Valbuena, J.3
  • 66
    • 84868342049 scopus 로고    scopus 로고
    • In vivo genome editing using a high-efficiency TALEN system
    • Bedell VM, Wang Y, Campbell JM et al. in vivo genome editing using a high-efficiency TALEN system. Nature 491(7422), 114-118 (2012).
    • (2012) Nature , vol.491 , Issue.7422 , pp. 114-118
    • Bedell, V.M.1    Wang, Y.2    Campbell, J.M.3
  • 67
    • 84874617789 scopus 로고    scopus 로고
    • Efficient genome editing in zebrafish using a CRISPR-cas system
    • Hwang WY, Fu Y, Reyon D et al. Efficient genome editing in zebrafish using a CRISPR-Cas system. Nat. Biotechnol. 31(3), 227-229 (2013).
    • (2013) Nat. Biotechnol. , vol.31 , Issue.3 , pp. 227-229
    • Hwang, W.Y.1    Fu, Y.2    Reyon, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.