Transgenic retinoic acid sensor lines in zebrafish indicate regions of available embryonic retinoic acid

Developmental Dynamics

Volumn 242, Issue 8, 2013, Pages 989-1000

  Mandal, Amrita ^a   Rydeen, Ariel ^a   Anderson, Jane ^a   Sorrell, Mollie R J ^a   Zygmunt, Tomas ^b   Torres Vázquez, Jesús ^b   Waxman, Joshua S ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Gal4 fusion proteins; Nuclear horomone receptors; Retinoic acid signaling; Transgenic zebrafish

Indexed keywords

DNA BINDING PROTEIN; PROTEIN VP16; RETINOIC ACID; RETINOIC ACID RECEPTOR; RETINOIC ACID RECEPTOR LIGAND BINDING DOMAIN; TRANSCRIPTION FACTOR GAL4; UNCLASSIFIED DRUG;

ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPORTER GENE; SENSOR; TRANSGENICS; ZEBRA FISH;

GAL4 FUSION PROTEINS; NUCLEAR HOROMONE RECEPTORS; RETINOIC ACID SIGNALING; TRANSGENIC ZEBRAFISH;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; RECEPTORS, RETINOIC ACID; TRANSCRIPTION FACTORS; TRETINOIN; ZEBRAFISH; ZEBRAFISH PROTEINS;

DANIO RERIO; VERTEBRATA;

EID: 84880631170     PISSN: 10588388     EISSN: 10970177     Source Type: Journal    
DOI: 10.1002/dvdy.23987     Document Type: Article

References (57)

1. Abu-Abed S, Dolle P, Metzger D, Beckett B, Chambon P, Petkovich M. 2001. The retinoic acid-metabolizing enzyme, CYP26A1, is essential for normal hindbrain patterning, vertebral identity, and development of posterior structures. Genes Dev 15:226-240.
2. Allenby G, Bocquel MT, Saunders M, Kazmer S, Speck J, Rosenberger M, Lovey A, Kastner P, Grippo JF, Chambon P, Levin AA. 1993. Retinoic acid receptors and retinoid X receptors: interactions with endogenous retinoic acids. Proc Natl Acad Sci USA 90:30-34.
3. Aranda A, Pascual A. 2001. Nuclear hormone receptors and gene expression. Physiol Rev 81:1269-1304.
4. Asakawa K, Suster ML, Mizusawa K, Nagayoshi S, Kotani T, Urasaki A, Kishimoto Y, Hibi M, Kawakami K. 2008. Genetic dissection of neural circuits by Tol2 transposon-mediated Gal4 gene and enhancer trapping in zebrafish. Proc Natl Acad Sci USA 105:1255-1260.
5. Balkan W, Colbert M, Bock C, Linney E. 1992. Transgenic indicator mice for studying activated retinoic acid receptors during development. Proc Natl Acad Sci USA 89:3347-3351.
6. Bastien J, Rochette-Egly C. 2004. Nuclear retinoid receptors and the transcription of retinoid-target genes. Gene 328:1-16.
7. Braitsch CM, Combs MD, Quaggin SE, Yutzey KE. 2012. Pod1/Tcf21 is regulated by retinoic acid signaling and inhibits differentiation of epicardium-derived cells into smooth muscle in the developing heart. Dev Biol (NY 1985) 368:345-357.
8. Campo-Paysaa F, Marletaz F, Laudet V, Schubert M. 2008. Retinoic acid signaling in development: tissue-specific functions and evolutionary origins. Genesis 46:640-656.
9. Chen TH, Chang TC, Kang JO, Choudhary B, Makita T, Tran CM, Burch JB, Eid H, Sucov HM. 2002. Epicardial induction of fetal cardiomyocyte proliferation via a retinoic acid-inducible trophic factor. Dev Biol 250:198-207.
10. Cooper KL, Hu JK, ten Berge D, Fernandez-Teran M, Ros MA, Tabin CJ. 2011. Initiation of proximal-distal patterning in the vertebrate limb by signals and growth. Science 332:1083-1086.
11. Davison JM, Akitake CM, Goll MG, Rhee JM, Gosse N, Baier H, Halpern ME, Leach SD, Parsons MJ. 2007. Transactivation from Gal4-VP16 transgenic insertions for tissue-specific cell labeling and ablation in zebrafish. Dev Biol (NY 1985) 304:811-824.
12. Duester G. 2008. Retinoic acid synthesis and signaling during early organogenesis. Cell 134:921-931.
13. Emoto Y, Wada H, Okamoto H, Kudo A, Imai Y. 2005. Retinoic acid-metabolizing enzyme Cyp26a1 is essential for determining territories of hindbrain and spinal cord in zebrafish. Dev Biol (NY 1985) 278:415-427.
14. Feng L, Hernandez RE, Waxman JS, Yelon D, Moens CB. 2010. Dhrs3a regulates retinoic acid biosynthesis through a feedback inhibition mechanism. Dev Biol (NY 1985) 338:1-14.
15. French CR, Erickson T, French DV, Pilgrim DB, Waskiewicz AJ. 2009. Gdf6a is required for the initiation of dorsal-ventral retinal patterning and lens development. Dev Biol (NY 1985) 333:37-47.
16. Goll MG, Anderson R, Stainier DY, Spradling AC, Halpern ME. 2009. Transcriptional silencing and reactivation in transgenic zebrafish. Genetics 182:747-755.
17. Grandel H, Lun K, Rauch GJ, Rhinn M, Piotrowski T, Houart C, Sordino P, Kuchler AM, Schulte-Merker S, Geisler R, Holder N, Wilson SW, Brand M. 2002. Retinoic acid signalling in the zebrafish embryo is necessary during pre-segmentation stages to pattern the anterior-posterior axis of the CNS and to induce a pectoral fin bud. Development 129:2851-2865.
18. Hale LA, Tallafuss A, Yan YL, Dudley L, Eisen JS, Postlethwait JH. 2006. Characterization of the retinoic acid receptor genes raraa, rarab and rarg during zebrafish development. Gene Express Patterns 6:546-555.
19. Heine UI, Roberts AB, Munoz EF, Roche NS, Sporn MB. 1985. Effects of retinoid deficiency on the development of the heart and vascular system of the quail embryo. Virchows Arch B Cell Pathol Incl Mol Pathol 50:135-152.
20. Hernandez RE, Rikhof HA, Bachmann R, Moens CB. 2004. vhnf1 integrates global RA patterning and local FGF signals to direct posterior hindbrain development in zebrafish. Development 131:4511-4520.
21. Hernandez RE, Putzke AP, Myers JP, Margaretha L, Moens CB. 2007. Cyp26 enzymes generate the retinoic acid response pattern necessary for hindbrain development. Development 134:177-187.
22. Kawakami K. 2005. Transposon tools and methods in zebrafish. Developmental dynamics: an official publication of the American Association of Anatomists234:244-254.
23. Kwan KM, Fujimoto E, Grabher C, Mangum BD, Hardy ME, Campbell DS, Parant JM, Yost HJ, Kanki JP, Chien CB. 2007. The Tol2kit: a multisite gateway-based construction kit for Tol2 transposon transgenesis constructs. Dev Dyn 236:3088-3099.
24. Lammer EJ, Chen DT, Hoar RM, Agnish ND, Benke PJ, Braun JT, Curry CJ, Fernhoff PM, Grix AW, Jr., Lott IT, et al. 1985. Retinoic acid embryopathy. N Engl J Med 313:837-841.
25. Lee Y, Hami D, De Val S, Kagermeier-Schenk B, Wills AA, Black BL, Weidinger G, Poss KD. 2009. Maintenance of blastemal proliferation by functionally diverse epidermis in regenerating zebrafish fins. Dev Biol (NY 1985) 331:270-280.
26. Li E, Sucov HM, Lee KF, Evans RM, Jaenisch R. 1993. Normal development and growth of mice carrying a targeted disruption of the alpha 1 retinoic acid receptor gene. Proc Natl Acad Sci USA 90:1590-1594.
27. Li P, Pashmforoush M, Sucov HM. 2010. Retinoic acid regulates differentiation of the secondary heart field and TGFbeta-mediated outflow tract septation. Dev Cell 18:480-485.
28. Liang D, Zhang M, Bao J, Zhang L, Xu X, Gao X, Zhao Q. 2008. Expressions of Raldh3 and Raldh4 during zebrafish early development. Gene Express Patterns 8:248-253.
29. Lohnes D, Kastner P, Dierich A, Mark M, LeMeur M, Chambon P. 1993. Function of retinoic acid receptor gamma in the mouse. Cell 73:643-658.
30. Lohnes D, Mark M, Mendelsohn C, Dolle P, Dierich A, Gorry P, Gansmuller A, Chambon P. 1994. Function of the retinoic acid receptors (RARs) during development (I). Craniofacial and skeletal abnormalities in RAR double mutants. Development 120:2723-2748.
31. Ma LH, Gilland E, Bass AH, Baker R. 2010. Ancestry of motor innervation to pectoral fin and forelimb. Nature Commun 1:49.
32. Mark M, Ghyselinck NB, Chambon P. 2009. Function of retinoic acid receptors during embryonic development. Nuclear Recept Signal 7:e002.
33. Maves L, Kimmel CB. 2005. Dynamic and sequential patterning of the zebrafish posterior hindbrain by retinoic acid. Dev Biol 285:593-605.
34. Mendelsohn C, Lohnes D, Decimo D, Lufkin T, LeMeur M, Chambon P, Mark M. 1994. Function of the retinoic acid receptors (RARs) during development (II). Multiple abnormalities at various stages of organogenesis in RAR double mutants. Development 120:2749-2771.
35. Nagpal S, Saunders M, Kastner P, Durand B, Nakshatri H, Chambon P. 1992. Promoter context- and response element-dependent specificity of the transcriptional activation and modulating functions of retinoic acid receptors. Cell 70:1007-1019.
36. Niederreither K, Dolle P. 2008. Retinoic acid in development: towards an integrated view. Nature Rev 9:541-553.
37. Niederreither K, Subbarayan V, Dolle P, Chambon P. 1999. Embryonic retinoic acid synthesis is essential for early mouse post-implantation development. Nat Genet 21:444-448.
38. Niederreither K, Vermot J, Messaddeq N, Schuhbaur B, Chambon P, Dolle P. 2001. Embryonic retinoic acid synthesis is essential for heart morphogenesis in the mouse. Development 128:1019-1031.
39. Oxtoby E, Jowett T. 1993. Cloning of the zebrafish krox-20 gene (krx-20) and its expression during hindbrain development. Nucleic Acids Res 21:1087-1095.
40. Perz-Edwards A, Hardison NL, Linney E. 2001. Retinoic acid-mediated gene expression in transgenic reporter zebrafish. Dev Biol 229:89-101.
41. Pittlik S, Domingues S, Meyer A, Begemann G. 2008. Expression of zebrafish aldh1a3 (raldh3) and absence of aldh1a1 in teleosts. Gene Express Patterns 8:141-147.
42. Rizzo R, Lammer EJ, Parano E, Pavone L, Argyle JC. 1991. Limb reduction defects in humans associated with prenatal isotretinoin exposure. Teratology 44:599-604.
43. Robu ME, Larson JD, Nasevicius A, Beiraghi S, Brenner C, Farber SA, Ekker SC. 2007. p53 activation by knockdown technologies. PLoS Genet 3:e78.
44. Rossant J, Zirngibl R, Cado D, Shago M, Giguere V. 1991. Expression of a retinoic acid response element-hsplacZ transgene defines specific domains of transcriptional activity during mouse embryogenesis. Genes Dev 5:1333-1344.
45. Russo JE, Hauguitz D, Hilton J. 1988. Inhibition of mouse cytosolic aldehyde dehydrogenase by 4-(diethylamino)benzaldehyde. Biochem Pharmacol 37:1639-1642.
46. Sakai Y, Meno C, Fujii H, Nishino J, Shiratori H, Saijoh Y, Rossant J, Hamada H. 2001. The retinoic acid-inactivating enzyme CYP26 is essential for establishing an uneven distribution of retinoic acid along the anterio-posterior axis within the mouse embryo. Genes Dev 15:213-225.
47. Sandell LL, Sanderson BW, Moiseyev G, Johnson T, Mushegian A, Young K, Rey JP, Ma JX, Staehling-Hampton K, Trainor PA. 2007. RDH10 is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development. Genes Dev 21:1113-1124.
48. Tiefenbach J, Moll PR, Nelson MR, Hu C, Baev L, Kislinger T, Krause HM. 2010. A live zebrafish-based screening system for human nuclear receptor ligand and cofactor discovery. PLoS One 5:e9797.
49. Warkany J, Schraffenberger E. 1946. Congenital malformations induced in rats by maternal vitamin A deficiency; defects of the eye. Arch Ophthalmol 35:150-169.
50. Waxman JS, Yelon D. 2007. Comparison of the expression patterns of newly identified zebrafish retinoic acid and retinoid X receptors. Dev Dyn 236:587-595.
51. Waxman JS, Yelon D. 2009. Increased Hox activity mimics the teratogenic effects of excess retinoic acid signaling. Dev Dyn 238:1207-1213.
52. Waxman JS, Yelon D. 2011. Zebrafish retinoic acid receptors function as context-dependent transcriptional activators. Dev Biol (NY 1985) 352:128-140.
53. Waxman JS, Keegan BR, Roberts RW, Poss KD, Yelon D. 2008. Hoxb5b acts downstream of retinoic acid signaling in the forelimb field to restrict heart field potential in zebrafish. Dev Cell 15:923-934.
54. White RJ, Nie Q, Lander AD, Schilling TF. 2007. Complex regulation of cyp26a1 creates a robust retinoic acid gradient in the zebrafish embryo. PLoS Biol 5:e304.
55. Wilson JG, Roth CB, Warkany J. 1953. An analysis of the syndrome of malformations induced by maternal vitamin A deficiency. Effects of restoration of vitamin A at various times during gestation. Am J Anat 92:189-217.
56. Wilson JG, Warkany J. 1949. Aortic-arch and cardiac anomalies in the offspring of vitamin A deficient rats. Am J Anat 85:113-155.
57. Zhang LX, Mills KJ, Dawson MI, Collins SJ, Jetten AM. 1995. Evidence for the involvement of retinoic acid receptor RAR alpha-dependent signaling pathway in the induction of tissue transglutaminase and apoptosis by retinoids. J Biol Chem 270:6022-6029.