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Volumn 45, Issue 6, 2013, Pages 540-552

The analysis of microsatellite instability in extracolonic gastrointestinal malignancy

Author keywords

Colorectal neoplasms; DNA mismatch repair; Gastrointestinal neoplasms; Hereditary non polyposis; Hereditary non polyposis colorectal cancer; HNPCC; Lynch syndrome; Microsatellite instability; MSI; Replication error phenotype

Indexed keywords

BILIARY TRACT TUMOR; GENETICS; HUMAN; MICROSATELLITE INSTABILITY; PANCREAS TUMOR; PATHOLOGY; REVIEW; SMALL INTESTINE; STOMACH TUMOR;

EID: 84887943622     PISSN: 00313025     EISSN: 14653931     Source Type: Journal    
DOI: 10.1097/PAT.0b013e3283653307     Document Type: Article
Times cited : (28)

References (151)
  • 1
    • 76549111046 scopus 로고    scopus 로고
    • Defective mismatch repair, microsatellite mutation bias, and variability in clinical cancer phenotypes
    • Shah S, Hile S, Eckert K. Defective mismatch repair, microsatellite mutation bias, and variability in clinical cancer phenotypes. Cancer Res 2010; 70: 431-5.
    • (2010) Cancer Res , vol.70 , pp. 431-435
    • Shah, S.1    Hile, S.2    Eckert, K.3
  • 2
  • 3
    • 0032534069 scopus 로고    scopus 로고
    • A national cancer institute workshop on microsatellite instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer
    • Boland CR, Thibodeau SN, Hamilton SR, et al. A national cancer institute workshop on microsatellite instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 1998; 58: 5248-57.
    • (1998) Cancer Res , vol.58 , pp. 5248-5257
    • Boland, C.R.1    Thibodeau, S.N.2    Hamilton, S.R.3
  • 4
    • 0036893598 scopus 로고    scopus 로고
    • Evaluation of tumor microsatellite instability using five quasimonomorphic mononucleotide repeats and pentaplex PCR
    • Suraweera N, Duval A, Reperant M, et al. Evaluation of tumor microsatellite instability using five quasimonomorphic mononucleotide repeats and pentaplex PCR. Gastroenterology 2002; 123: 1804-11.
    • (2002) Gastroenterology , vol.123 , pp. 1804-1811
    • Suraweera, N.1    Duval, A.2    Reperant, M.3
  • 5
    • 10744233937 scopus 로고    scopus 로고
    • Revised bethesda guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability
    • Umar A, Boland CR, Terdiman J, et al. Revised bethesda guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability. J Natl Cancer Inst 2004; 96: 261-8.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 261-268
    • Umar, A.1    Boland, C.R.2    Terdiman, J.3
  • 6
    • 12844262943 scopus 로고    scopus 로고
    • Quasimonomorphic mononucleotide repeats for high-level microsatellite instability analysis
    • Buhard O, Suraweera N, Lectard A, Duval A, Hamelin R. Quasimonomorphic mononucleotide repeats for high-level microsatellite instability analysis. Dis Markers 2004; 20: 251-7.
    • (2004) Dis Markers , vol.20 , pp. 251-257
    • Buhard, O.1    Suraweera, N.2    Lectard, A.3    Duval, A.4    Hamelin, R.5
  • 7
    • 12844262940 scopus 로고    scopus 로고
    • Development of a fluorescent multiplex assay for detection of MSI-high tumors
    • Bacher J, Flanagan L, Smalley R, et al. Development of a fluorescent multiplex assay for detection of MSI-high tumors. Dis Markers 2004; 20: 237-50.
    • (2004) Dis Markers , vol.20 , pp. 237-250
    • Bacher, J.1    Flanagan, L.2    Smalley, R.3
  • 8
    • 33845608798 scopus 로고    scopus 로고
    • Classification of colorectal cancer based on correlation of clinical, morphological and molecular features
    • Jass Jr. Classification of colorectal cancer based on correlation of clinical, morphological and molecular features. Histopathology 2007; 50: 113-30.
    • (2007) Histopathology , vol.50 , pp. 113-130
    • Jass, J.R.1
  • 9
    • 33847712926 scopus 로고    scopus 로고
    • Performance of different microsatellite marker panels for detection of mismatch repair-deficient colorectal tumors
    • Xicola R, Llor X, Pons E, et al. Performance of different microsatellite marker panels for detection of mismatch repair-deficient colorectal tumors. J Natl Cancer Inst 2007; 99: 244-52.
    • (2007) J Natl Cancer Inst , vol.99 , pp. 244-252
    • Xicola, R.1    Llor, X.2    Pons, E.3
  • 10
    • 33745977120 scopus 로고    scopus 로고
    • Comparison of the microsatellite instability analysis system and the Bethesda panel for the determination of microsatellite instability in colorectal cancers
    • Murphy K, Zhang S, Geiger T, et al. Comparison of the microsatellite instability analysis system and the Bethesda panel for the determination of microsatellite instability in colorectal cancers. J Mol Diagn 2006; 8: 305- 11.
    • (2006) J Mol Diagn , vol.8 , pp. 305-311
    • Murphy, K.1    Zhang, S.2    Geiger, T.3
  • 11
    • 0033063711 scopus 로고    scopus 로고
    • New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the international collaborative group on HNPCC
    • Vasen HF, Watson P, Mecklin JP, Lynch HT. New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the international collaborative group on HNPCC. Gastroenterology 1999; 116: 1453-6.
    • (1999) Gastroenterology , vol.116 , pp. 1453-1456
    • Vasen, H.F.1    Watson, P.2    Mecklin, J.P.3    Lynch, H.T.4
  • 12
    • 0032941343 scopus 로고    scopus 로고
    • Cancer risk in mutation carriers of DNA-mismatch-repair genes
    • Aarnio M, Sankila R, Pukkala E, et al. Cancer risk in mutation carriers of DNA-mismatch-repair genes. Int J Cancer 1999; 81: 214-8.
    • (1999) Int J Cancer , vol.81 , pp. 214-218
    • Aarnio, M.1    Sankila, R.2    Pukkala, E.3
  • 13
    • 58849130663 scopus 로고    scopus 로고
    • Cumulative lifetime incidence of extracolonic cancers in Lynch syndrome: A report of 121 families with proven mutations
    • Barrow E, Robinson L, AlduaijW, et al. Cumulative lifetime incidence of extracolonic cancers in Lynch syndrome: A report of 121 families with proven mutations. Clin Genet 2009; 75: 141-9.
    • (2009) Clin Genet , vol.75 , pp. 141-149
    • Barrow, E.1    Alduaijw, R.L.2
  • 14
    • 84880922857 scopus 로고    scopus 로고
    • The role of epigenetics in Lynch syndrome
    • Hitchins M. The role of epigenetics in Lynch syndrome. Fam Cancer 2013; 12: 189-205.
    • (2013) Fam Cancer , vol.12 , pp. 189-205
    • Hitchins, M.1
  • 15
    • 0034827025 scopus 로고    scopus 로고
    • The frequency of hereditary defective mismatch repair in a prospective series of unselected colorectal carcinomas
    • Cunningham JM, Kim CY, Christensen ER, et al. The frequency of hereditary defective mismatch repair in a prospective series of unselected colorectal carcinomas. Am J Hum Genet 2001; 69: 780-90.
    • (2001) Am J Hum Genet , vol.69 , pp. 780-790
    • Cunningham, J.M.1    Kim, C.Y.2    Christensen, E.R.3
  • 16
    • 17144441735 scopus 로고    scopus 로고
    • Causes of microsatellite instability in colorectal tumors: Implications for hereditary nonpolyposis colorectal cancer screening
    • Potocnik U, Glavac D, Golouh R, Ravnik Glavac M. Causes of microsatellite instability in colorectal tumors: Implications for hereditary nonpolyposis colorectal cancer screening. Cancer Genet Cytogenet 2001; 126: 85-96.
    • (2001) Cancer Genet Cytogenet , vol.126 , pp. 85-96
    • Potocnik, U.1    Glavac, D.2    Golouh, R.3    Ravnik Glavac, M.4
  • 17
    • 34250639863 scopus 로고    scopus 로고
    • Distinction of hereditary nonpolyposis colorectal cancer and sporadic microsatellite-unstable colorectal cancer through quantification of MLH1 methylation by real-time PCR
    • Bettstetter M, Dechant S, Ruemmele P, et al. Distinction of hereditary nonpolyposis colorectal cancer and sporadic microsatellite-unstable colorectal cancer through quantification of MLH1 methylation by real-time PCR. Clin Cancer Res 2007; 13: 3221-8.
    • (2007) Clin Cancer Res , vol.13 , pp. 3221-3228
    • Bettstetter, M.1    Dechant, S.2    Ruemmele, P.3
  • 18
    • 33745181120 scopus 로고    scopus 로고
    • Histologic features distinguish microsatellite-high from microsatellite-low and microsatellite-stable colorectal carcinomas, but do not differentiate germline mutations from methylation of the MLH1 promoter
    • Yearsley M, Hampel H, Lehman A, Nakagawa H, de la Chapelle A, Frankel W. Histologic features distinguish microsatellite-high from microsatellite-low and microsatellite-stable colorectal carcinomas, but do not differentiate germline mutations from methylation of the MLH1 promoter. Hum Pathol 2006; 37: 831-8.
    • (2006) Hum Pathol , vol.37 , pp. 831-838
    • Yearsley, M.1    Hampel, H.2    Lehman, A.3    Nakagawa, H.4    De La Chapelle, A.5    Frankel, W.6
  • 19
    • 77957197346 scopus 로고    scopus 로고
    • Microsatellite instability as a marker of prognosis and response to therapy:Ameta-analysis of colorectal cancer survival data
    • Guastadisegni C, Colafranceschi M, Ottini L, Dogliotti E. Microsatellite instability as a marker of prognosis and response to therapy:Ameta-analysis of colorectal cancer survival data. Eur J Cancer 2010; 46: 2788-98.
    • (2010) Eur J Cancer , vol.46 , pp. 2788-2798
    • Guastadisegni, C.1    Colafranceschi, M.2    Ottini, L.3    Dogliotti, E.4
  • 20
    • 0037381250 scopus 로고    scopus 로고
    • The clinical importance and prognostic implications of microsatellite instability in sporadic cancer
    • Lawes DA, SenGupta S, Boulos PB. The clinical importance and prognostic implications of microsatellite instability in sporadic cancer. Eur J Surg Oncol 2003; 29: 201-12.
    • (2003) Eur J Surg Oncol , vol.29 , pp. 201-212
    • Lawes, D.A.1    Sengupta, S.2    Boulos, P.B.3
  • 21
    • 84866262267 scopus 로고    scopus 로고
    • Clinicopathological features and management of cancers in Lynch syndrome
    • Aarnio M. Clinicopathological features and management of cancers in Lynch syndrome. Pathol Res Int 2012; 2012: 350309.
    • (2012) Pathol Res Int , vol.2012 , pp. 350309
    • Aarnio, M.1
  • 22
    • 14644441621 scopus 로고    scopus 로고
    • Microsatellite instability and DNA mismatch repair deficiency testing in hereditary and sporadic gastrointestinal cancers
    • Gologan A, Sepulveda A. Microsatellite instability and DNA mismatch repair deficiency testing in hereditary and sporadic gastrointestinal cancers. Clin Lab Med 2005; 25: 179-96.
    • (2005) Clin Lab Med , vol.25 , pp. 179-196
    • Gologan, A.1    Sepulveda, A.2
  • 23
    • 47649123223 scopus 로고    scopus 로고
    • Immunohistochemistry versus microsatellite instability testing for screening colorectal cancer patients at risk for hereditary nonpolyposis colorectal cancer syndrome. Part I. The utility of immunohistochemistry
    • Shia J. Immunohistochemistry versus microsatellite instability testing for screening colorectal cancer patients at risk for hereditary nonpolyposis colorectal cancer syndrome. part I. The utility of immunohistochemistry. J Mol Diagn 2008; 10: 293-300.
    • (2008) J Mol Diagn , vol.10 , pp. 293-300
    • Shia, J.1
  • 24
    • 12244278227 scopus 로고    scopus 로고
    • Correlation of mismatch repair genes immunohistochemistry and microsatellite instability status in HNPCC-associated tumours
    • Ruszkiewicz A, Bennett G, Moore J, et al. Correlation of mismatch repair genes immunohistochemistry and microsatellite instability status in HNPCC-associated tumours. Pathology 2002; 34: 541-7.
    • (2002) Pathology , vol.34 , pp. 541-547
    • Ruszkiewicz, A.1    Bennett, G.2    Moore, J.3
  • 25
    • 84866500834 scopus 로고    scopus 로고
    • Unusual DNA mismatch repairdeficient tumors in Lynch syndrome: A report of new cases and review of the literature
    • Karamurzin Y, Zeng Z, Stadler Z, et al. Unusual DNA mismatch repairdeficient tumors in Lynch syndrome: A report of new cases and review of the literature. Hum Pathol 2012; 43: 1677-87.
    • (2012) Hum Pathol , vol.43 , pp. 1677-1687
    • Karamurzin, Y.1    Zeng, Z.2    Stadler, Z.3
  • 26
    • 10744220882 scopus 로고    scopus 로고
    • Prognostic value of hMLH1 methylation and microsatellite instability in pancreatic endocrine neoplasms
    • House M, Herman J, Guo M, et al. Prognostic value of hMLH1 methylation and microsatellite instability in pancreatic endocrine neoplasms. Surgery 2003; 134: 902-8.
    • (2003) Surgery , vol.134 , pp. 902-908
    • House, M.1    Herman, J.2    Guo, M.3
  • 27
    • 69949109032 scopus 로고    scopus 로고
    • Clinical implications of microsatellite instability and MLH1 gene inactivation in sporadic insulinomas
    • Mei M, Deng D, Liu T, et al. Clinical implications of microsatellite instability and MLH1 gene inactivation in sporadic insulinomas. J Clin Endocrinol Metab 2009; 94: 3448-57.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 3448-3457
    • Mei, M.1    Deng, D.2    Liu, T.3
  • 28
    • 20244387702 scopus 로고    scopus 로고
    • HNPCC-associated small bowel cancer: Clinical and molecular characteristics
    • Schulmann K, Brasch F, Kunstmann E, et al. HNPCC-associated small bowel cancer: Clinical and molecular characteristics. Gastroenterology 2005; 128: 590-9.
    • (2005) Gastroenterology , vol.128 , pp. 590-599
    • Schulmann, K.1    Brasch, F.2    Kunstmann, E.3
  • 29
    • 82655171642 scopus 로고    scopus 로고
    • Loss of expression of DNA mismatch repair proteins is rare in pancreatic and small intestinal neuroendocrine tumors
    • Arnason T, Sapp H, Rayson D, et al. Loss of expression of DNA mismatch repair proteins is rare in pancreatic and small intestinal neuroendocrine tumors. Arch Pathol Lab Med 2011; 135: 1539-44.
    • (2011) Arch Pathol Lab Med , vol.135 , pp. 1539-1544
    • Arnason, T.1    Sapp, H.2    Rayson, D.3
  • 30
    • 40049111329 scopus 로고    scopus 로고
    • Large proportion of low frequency microsatellite-instability and loss of heterozygosity in pheochromocytoma and endocrine tumors detected with an extended marker panel
    • Kupka S, Haack B, Zdichavsky M, et al. Large proportion of low frequency microsatellite-instability and loss of heterozygosity in pheochromocytoma and endocrine tumors detected with an extended marker panel. J Cancer Res Clin Oncol 2008; 134: 463-71.
    • (2008) J Cancer Res Clin Oncol , vol.134 , pp. 463-471
    • Kupka, S.1    Haack, B.2    Zdichavsky, M.3
  • 31
    • 12344321343 scopus 로고    scopus 로고
    • Microsatellite instability and gene mutations in transforming growth factor-beta type II receptor are absent in small bowel carcinoid tumors
    • Kidd M, Eick G, Shapiro M, Camp R, Mane S, Modlin I. Microsatellite instability and gene mutations in transforming growth factor-beta type II receptor are absent in small bowel carcinoid tumors. Cancer 2005; 103: 229-36.
    • (2005) Cancer , vol.103 , pp. 229-236
    • Kidd, M.1    Eick, G.2    Shapiro, M.3    Camp, R.4    Mane, S.5    Modlin, I.6
  • 32
    • 0032898651 scopus 로고    scopus 로고
    • Microsatellite instability and mismatch repair gene inactivation in sporadic pancreatic and colon tumours
    • Ghimenti C, Tannergard P,Wahlberg S, et al. Microsatellite instability and mismatch repair gene inactivation in sporadic pancreatic and colon tumours. Br J Cancer 1999; 80: 11-6.
    • (1999) Br J Cancer , vol.80 , pp. 11-16
    • Ghimenti, C.1    Tannergard, P.2    Wahlberg, S.3
  • 33
    • 79951593439 scopus 로고    scopus 로고
    • High microsatellite instability predicts good prognosis in intestinal-type gastric cancers
    • Kim H, An J, Noh S, Shin S, Lee Y. High microsatellite instability predicts good prognosis in intestinal-type gastric cancers. J Gastroenterol Hepatol 2011; 26: 585-92.
    • (2011) J Gastroenterol Hepatol , vol.26 , pp. 585-592
    • Kim, H.1    An, J.2    Noh, S.3    Shin, S.4    Lee, Y.5
  • 34
    • 68949161979 scopus 로고    scopus 로고
    • Correlation of microsatellite instability at multiple loci with long-term survival in advanced gastric carcinoma
    • Corso G, Pedrazzani C, Marrelli D, Pascale V, Pinto E, Roviello F. Correlation of microsatellite instability at multiple loci with long-term survival in advanced gastric carcinoma. Arch Surg 2009; 144: 722-7.
    • (2009) Arch Surg , vol.144 , pp. 722-727
    • Corso, G.1    Pedrazzani, C.2    Marrelli, D.3    Pascale, V.4    Pinto, E.5    Roviello, F.6
  • 35
    • 33644998539 scopus 로고    scopus 로고
    • Microsatellite instability in gastric cancer is associated with better prognosis in only stage II cancers
    • Beghelli S, de Manzoni G, Barbi S, et al. Microsatellite instability in gastric cancer is associated with better prognosis in only stage II cancers. Surgery 2006; 139: 347-56.
    • (2006) Surgery , vol.139 , pp. 347-356
    • Beghelli, S.1    De Manzoni, G.2    Barbi, S.3
  • 36
    • 61449224723 scopus 로고    scopus 로고
    • Clinicopathologic characteristics and outcomes of gastric cancers with the MSI-H phenotype
    • Seo H, Chang Y, Joo S, et al. Clinicopathologic characteristics and outcomes of gastric cancers with the MSI-H phenotype. J Surg Oncol 2009; 99: 143-7.
    • (2009) J Surg Oncol , vol.99 , pp. 143-147
    • Seo, H.1    Chang, Y.2    Joo, S.3
  • 37
    • 79551478326 scopus 로고    scopus 로고
    • MSI phenotype and MMR alterations in familial and sporadic gastric cancer
    • Leite M, Corso G, Sousa S, et al. MSI phenotype and MMR alterations in familial and sporadic gastric cancer. Int J Cancer 2011; 128: 1606-13.
    • (2011) Int J Cancer , vol.128 , pp. 1606-1613
    • Leite, M.1    Corso, G.2    Sousa, S.3
  • 38
    • 67651219459 scopus 로고    scopus 로고
    • Analysis of microsatellite instability, protein expression and methylation status ofhMLH1andhMSH2 genes in gastric carcinomas
    • Gu M, Kim D, Bae Y, Choi J, Kim S, Song S. Analysis of microsatellite instability, protein expression and methylation status ofhMLH1andhMSH2 genes in gastric carcinomas. Hepatogastroenterology 2009; 56: 899-904.
    • (2009) Hepatogastroenterology , vol.56 , pp. 899-904
    • Gu, M.1    Kim, D.2    Bae, Y.3    Choi, J.4    Kim, S.5    Song, S.6
  • 39
    • 84861613037 scopus 로고    scopus 로고
    • Microsatellite instability in sporadic gastric cancer: Its prognostic role and guidance for 5-FU based chemotherapy after R0 resection
    • An J, Kim H, Cheong J, Hyung W, Noh S. Microsatellite instability in sporadic gastric cancer: Its prognostic role and guidance for 5-FU based chemotherapy after R0 resection. Int J Cancer 2012; 131: 505-11.
    • (2012) Int J Cancer , vol.131 , pp. 505-511
    • An, J.1    Kim, H.2    Cheong, J.3    Hyung, W.4    Noh, S.5
  • 40
    • 0036089129 scopus 로고    scopus 로고
    • Distinct clinical features and outcomes of gastric cancers with microsatellite instability
    • Lee HS, Choi S, Lee HK, et al. Distinct clinical features and outcomes of gastric cancers with microsatellite instability. Mod Pathol 2002; 15: 632- 40.
    • (2002) Mod Pathol , vol.15 , pp. 632-640
    • Lee, H.S.1    Choi, S.2    Lee, H.K.3
  • 41
    • 0034691567 scopus 로고    scopus 로고
    • Prognostic implications of microsatellite genotypes in gastric carcinoma
    • Choi SW, Choi JR, Chung YJ, Kim KM, Rhyu MG. Prognostic implications of microsatellite genotypes in gastric carcinoma. Int J Cancer 2000; 89: 378-83.
    • (2000) Int J Cancer , vol.89 , pp. 378-383
    • Choi, S.W.1    Choi, J.R.2    Chung, Y.J.3    Kim, K.M.4    Rhyu, M.G.5
  • 42
    • 84874987280 scopus 로고    scopus 로고
    • Microsatellite instability status in gastric cancer: A reappraisal of its clinical significance and relationship with mucin phenotypes
    • Kim J, Shin N, Kim A, et al. Microsatellite instability status in gastric cancer: A reappraisal of its clinical significance and relationship with mucin phenotypes. Korean J Pathol 2013; 47: 28-35.
    • (2013) Korean J Pathol , vol.47 , pp. 28-35
    • Kim, J.1    Shin, N.2    Kim, A.3
  • 43
    • 44649157590 scopus 로고    scopus 로고
    • Gastric cancer with high-level microsatellite instability: Target gene mutations, clinicopathologic features, and long-term survival
    • Falchetti M, Saieva C, Lupi R, et al. Gastric cancer with high-level microsatellite instability: Target gene mutations, clinicopathologic features, and long-term survival. Hum Pathol 2008; 39: 925-32.
    • (2008) Hum Pathol , vol.39 , pp. 925-932
    • Falchetti, M.1    Saieva, C.2    Lupi, R.3
  • 44
    • 0031710793 scopus 로고    scopus 로고
    • The clinicopathological features of gastric carcinomas with microsatellite instability may be mediated by mutations of different 'target genes': A study of the TGFbeta RII, IGFII R, and BAX genes
    • Oliveira C, Seruca R, Seixas M, Sobrinho Simoes M. The clinicopathological features of gastric carcinomas with microsatellite instability may be mediated by mutations of different 'target genes': A study of the TGFbeta RII, IGFII R, and BAX genes. Am J Pathol 1998; 153: 1211-9.
    • (1998) Am J Pathol , vol.153 , pp. 1211-1219
    • Oliveira, C.1    Seruca, R.2    Seixas, M.3    Sobrinho Simoes, M.4
  • 45
    • 0033802550 scopus 로고    scopus 로고
    • Microsatellite instability, prognosis and metastasis in gastric cancers from a low-risk population
    • Schneider BG, Bravo JC, Roa JC, et al. Microsatellite instability, prognosis and metastasis in gastric cancers from a low-risk population. Int J Cancer 2000; 89: 444-52.
    • (2000) Int J Cancer , vol.89 , pp. 444-452
    • Schneider, B.G.1    Bravo, J.C.2    Roa, J.C.3
  • 46
    • 0033038815 scopus 로고    scopus 로고
    • Gastric cancers of the microsatellite mutator phenotype display characteristic genetic and clinical features
    • Yamamoto H, Perez Piteira J, Yoshida T, et al. Gastric cancers of the microsatellite mutator phenotype display characteristic genetic and clinical features. Gastroenterology 1999; 116: 1348-57.
    • (1999) Gastroenterology , vol.116 , pp. 1348-1357
    • Yamamoto, H.1    Perez Piteira, J.2    Yoshida, T.3
  • 47
    • 68949205565 scopus 로고    scopus 로고
    • Chemosensitivity and survival in gastric cancer patients with microsatellite instability
    • Oki E, Kakeji Y, Zhao Y, et al. Chemosensitivity and survival in gastric cancer patients with microsatellite instability. Ann Surg Oncol 2009; 16: 2510-5.
    • (2009) Ann Surg Oncol , vol.16 , pp. 2510-2515
    • Oki, E.1    Kakeji, Y.2    Zhao, Y.3
  • 48
    • 26944470803 scopus 로고    scopus 로고
    • Tumor microsatellite instability in early onset gastric cancer
    • Bacani J, Zwingerman R, Di Nicola N, et al. Tumor microsatellite instability in early onset gastric cancer. J Mol Diagn 2005; 7: 465-77.
    • (2005) J Mol Diagn , vol.7 , pp. 465-477
    • Bacani, J.1    Zwingerman, R.2    Di Nicola, N.3
  • 49
    • 84878111820 scopus 로고    scopus 로고
    • Differential clinicopathologic features in microsatellite-unstable gastric cancers with and without MLH1 methylation
    • Kim K, Lee T, Cho N, Yang H, Kim W, Kang G. Differential clinicopathologic features in microsatellite-unstable gastric cancers with and without MLH1 methylation. Hum Pathol 2013; 44: 1055-64.
    • (2013) Hum Pathol , vol.44 , pp. 1055-1064
    • Kim, K.1    Lee, T.2    Cho, N.3    Yang, H.4    Kim, W.5    Kang, G.6
  • 50
    • 84885960850 scopus 로고    scopus 로고
    • Frequent microsatellite instability in papillary and solid-type poorly differentiated adenocarcinomas of the stomach
    • Dec 29: (Epub ahead of print)
    • Arai T, Sakurai U, Sawabe M, et al. Frequent microsatellite instability in papillary and solid-type, poorly differentiated adenocarcinomas of the stomach. Gastric Cancer 2012; Dec 29: (Epub ahead of print).
    • (2012) Gastric Cancer
    • Arai, T.1    Sakurai, U.2    Sawabe, M.3
  • 51
    • 0032848687 scopus 로고    scopus 로고
    • Distinct methylation pattern and microsatellite instability in sporadic gastric cancer
    • Suzuki H, Itoh F, Toyota M, et al. Distinct methylation pattern and microsatellite instability in sporadic gastric cancer. Int J Cancer 1999; 83: 309-13.
    • (1999) Int J Cancer , vol.83 , pp. 309-313
    • Suzuki, H.1    Itoh, F.2    Toyota, M.3
  • 52
    • 33750968819 scopus 로고    scopus 로고
    • Frequency of immunohistochemical loss of mismatch repair protein in double primary cancers of the colorectum and stomach in Japan
    • Hayashi T, Arai M, Ueno M, et al. Frequency of immunohistochemical loss of mismatch repair protein in double primary cancers of the colorectum and stomach in Japan. Dis Colon Rectum 2006; 49 (Suppl): S23-9.
    • (2006) Dis Colon Rectum , vol.49 , Issue.SUPPL.
    • Hayashi, T.1    Arai, M.2    Ueno, M.3
  • 53
    • 84867843715 scopus 로고    scopus 로고
    • Microsatellite instability is associated with a better prognosis for gastric cancer patients after curative surgery
    • FangW, Chang S, Lan Y, et al. Microsatellite instability is associated with a better prognosis for gastric cancer patients after curative surgery.World J Surg 2012; 36: 2131-8.
    • (2012) World J Surg , vol.36 , pp. 2131-2138
    • Fang, W.1    Chang, S.2    Lan, Y.3
  • 54
    • 77957993657 scopus 로고    scopus 로고
    • Comparative features of colorectal and gastric cancers with microsatellite instability in Chinese patients
    • Huang Y, Yuan Y, GeW, Hu H, Zhang S, Zheng S. Comparative features of colorectal and gastric cancers with microsatellite instability in Chinese patients. J Zhejiang Univ (Sci) B 2010; 11: 647-53.
    • (2010) J Zhejiang Univ (Sci) B , vol.11 , pp. 647-653
    • Huang, Y.1    Yuan, Y.2    Ge, W.3    Hu, H.4    Zhang, S.5    Zheng, S.6
  • 55
    • 0034006762 scopus 로고    scopus 로고
    • Distinct clinicopathologic and genetic profiles in sporadic gastric cancer with different mutator phenotypes
    • Wu MS, Lee CW, Shun CT, et al. Distinct clinicopathologic and genetic profiles in sporadic gastric cancer with different mutator phenotypes. Genes Chromosomes Cancer 2000; 27: 403-11.
    • (2000) Genes Chromosomes Cancer , vol.27 , pp. 403-411
    • Wu, M.S.1    Lee, C.W.2    Shun, C.T.3
  • 56
    • 0034661742 scopus 로고    scopus 로고
    • Methylation of the hMLH1 promoter but no hMLH1 mutations in sporadic gastric carcinomas with high-level microsatellite instability
    • Bevilacqua RA, Simpson AJ. Methylation of the hMLH1 promoter but no hMLH1 mutations in sporadic gastric carcinomas with high-level microsatellite instability. Int J Cancer 2000; 87: 200-3.
    • (2000) Int J Cancer , vol.87 , pp. 200-203
    • Bevilacqua, R.A.1    Simpson, A.J.2
  • 57
    • 84876499666 scopus 로고    scopus 로고
    • KRAS and BRAF mutations are rare and related to DNA mismatch repair deficiency in gastric cancer from the east and the west: Results from a large international multicentre study
    • van Grieken NCT, Aoyma T, Chambers PA, et al. KRAS and BRAF mutations are rare and related to DNA mismatch repair deficiency in gastric cancer from the east and the west: Results from a large international multicentre study. Br J Cancer 2013; 108: 1495-501.
    • (2013) Br J Cancer , vol.108 , pp. 1495-1501
    • Van Grieken, N.C.T.1    Aoyma, T.2    Chambers, P.A.3
  • 58
    • 34347209468 scopus 로고    scopus 로고
    • Is gastric cancer part of the tumour spectrum of hereditary non-polyposis colorectal cancer? A molecular genetic study
    • Gylling A, Abdel Rahman WM, Juhola M, et al. Is gastric cancer part of the tumour spectrum of hereditary non-polyposis colorectal cancer? A molecular genetic study. Gut 2007; 56: 926-33.
    • (2007) Gut , vol.56 , pp. 926-933
    • Gylling, A.1    Abdel Rahman, W.M.2    Juhola, M.3
  • 59
    • 0036329324 scopus 로고    scopus 로고
    • Microsatellite instability in Japanese vs European American patients with gastric cancer
    • Theuer C, Campbell B, Peel D, et al. Microsatellite instability in Japanese vs European American patients with gastric cancer. Arch Surg 2002; 137: 960-5.
    • (2002) Arch Surg , vol.137 , pp. 960-965
    • Theuer, C.1    Campbell, B.2    Peel, D.3
  • 60
    • 0032870152 scopus 로고    scopus 로고
    • Marked differences in the frequency of microsatellite instability in gastric cancer from different countries
    • Sepulveda AR, Santos AC, Yamaoka Y, et al. Marked differences in the frequency of microsatellite instability in gastric cancer from different countries. Am J Gastroenterol 1999; 94: 3034-8.
    • (1999) Am J Gastroenterol , vol.94 , pp. 3034-3038
    • Sepulveda, A.R.1    Santos, A.C.2    Yamaoka, Y.3
  • 61
    • 78651289140 scopus 로고    scopus 로고
    • Gastric cancers of western European and African patients show different patterns of genomic instability
    • Buffart T, Louw M, van Grieken NCT, et al. Gastric cancers of western European and African patients show different patterns of genomic instability. BMC Med Genom 2011; 4: 7-17.
    • (2011) BMC Med Genom , vol.4 , pp. 7-17
    • Buffart, T.1    Louw, M.2    Van Grieken, N.C.T.3
  • 62
    • 44949202465 scopus 로고    scopus 로고
    • The risk of extra-colonic, extra-endometrial cancer in the Lynch syndrome
    • Watson P, Vasen HFA, Mecklin J, et al. The risk of extra-colonic, extra-endometrial cancer in the Lynch syndrome. Int J Cancer 2008; 123: 444-9.
    • (2008) Int J Cancer , vol.123 , pp. 444-449
    • Watson, P.1    Vasen, H.F.A.2    Mecklin, J.3
  • 63
    • 0029585997 scopus 로고
    • Lifetime risk of different cancers in hereditary non-polyposis colorectal cancer (HNPCC) syndrome
    • Aarnio M, Mecklin JP, Aaltonen LA, Nystrom-Lahti M, Jarvinen HJ. Lifetime risk of different cancers in hereditary non-polyposis colorectal cancer (HNPCC) syndrome. Int J Cancer 1995; 64: 430-3.
    • (1995) Int J Cancer , vol.64 , pp. 430-433
    • Aarnio, M.1    Mecklin, J.P.2    Aaltonen, L.A.3    Nystrom-Lahti, M.4    Jarvinen, H.J.5
  • 64
    • 0035886698 scopus 로고    scopus 로고
    • MSH2 mutation carriers are at higher risk of cancer than MLH1 mutation carriers: A study of hereditary nonpolyposis colorectal cancer families
    • Vasen HF, Stormorken A, Menko FH, et al. MSH2 mutation carriers are at higher risk of cancer than MLH1 mutation carriers: A study of hereditary nonpolyposis colorectal cancer families. J Clin Oncol 2001; 19: 4074-80.
    • (2001) J Clin Oncol , vol.19 , pp. 4074-4080
    • Vasen, H.F.1    Stormorken, A.2    Menko, F.H.3
  • 65
    • 0033897383 scopus 로고    scopus 로고
    • Risk of gastric cancer in hereditary nonpolyposis colorectal cancer in Korea
    • Park YJ, Shin KH, Park JG. Risk of gastric cancer in hereditary nonpolyposis colorectal cancer in Korea. Clin Cancer Res 2000; 6: 2994-8.
    • (2000) Clin Cancer Res , vol.6 , pp. 2994-2998
    • Park, Y.J.1    Shin, K.H.2    Park, J.G.3
  • 67
    • 12644292106 scopus 로고
    • The two histological main types of gastric carcinoma: Diffuse and so-called intestinal-type carcinoma. An attempt at a histo-clinical classification
    • Lauren P. The two histological main types of gastric carcinoma: Diffuse and so-called intestinal-type carcinoma. An attempt at a histo-clinical classification. Acta Pathol Microbiol Scand 1965; 64: 31-49.
    • (1965) Acta Pathol Microbiol Scand , vol.64 , pp. 31-49
    • Lauren, P.1
  • 68
    • 0017385753 scopus 로고
    • Gastric carcinoma. A pathobiological classification
    • Ming SC. Gastric carcinoma. A pathobiological classification. Cancer 1977; 39: 2475-85.
    • (1977) Cancer , vol.39 , pp. 2475-2485
    • Ming, S.C.1
  • 69
    • 0034879583 scopus 로고    scopus 로고
    • The role of histological investigation in prognostic evaluation of advanced gastric cancer. Analysis of histological structure and molecular changes compared with invasive pattern and stage
    • Chiaravalli AM, Cornaggia M, Furlan D, et al. The role of histological investigation in prognostic evaluation of advanced gastric cancer. Analysis of histological structure and molecular changes compared with invasive pattern and stage. Virchows Arch 2001; 439: 158-69.
    • (2001) Virchows Arch , vol.439 , pp. 158-169
    • Chiaravalli, A.M.1    Cornaggia, M.2    Furlan, D.3
  • 70
    • 0034535952 scopus 로고    scopus 로고
    • MSI-L gastric carcinomas share the hMLH1 methylation status of MSI-H carcinomas but not their clinicopathological profile
    • Pinto M, Oliveira C, Machado JC, et al. MSI-L gastric carcinomas share the hMLH1 methylation status of MSI-H carcinomas but not their clinicopathological profile. Lab Invest 2000; 80: 1915-23.
    • (2000) Lab Invest , vol.80 , pp. 1915-1923
    • Pinto, M.1    Oliveira, C.2    Machado, J.C.3
  • 71
    • 68449100164 scopus 로고    scopus 로고
    • Evidence of tumor microsatellite instability in gastric cancer with familial aggregation
    • Pedrazzani C, Corso G, Velho S, et al. Evidence of tumor microsatellite instability in gastric cancer with familial aggregation. Fam Cancer 2009; 8: 215-20.
    • (2009) Fam Cancer , vol.8 , pp. 215-220
    • Pedrazzani, C.1    Corso, G.2    Velho, S.3
  • 72
    • 33745815312 scopus 로고    scopus 로고
    • Tumor differentiation phenotype in gastric differentiated-type tumors and its relation to tumor invasion and genetic alterations
    • Yamazaki K, Tajima Y, Makino R, et al. Tumor differentiation phenotype in gastric differentiated-type tumors and its relation to tumor invasion and genetic alterations. World J Gastroenterol 2006; 12: 3803-9.
    • (2006) World J Gastroenterol , vol.12 , pp. 3803-3809
    • Yamazaki, K.1    Tajima, Y.2    Makino, R.3
  • 73
    • 33751292686 scopus 로고    scopus 로고
    • Gastric and intestinal phenotypic marker expression in early differentiated-type tumors of the stomach: Clinicopathologic significance and genetic background
    • Tajima Y, Yamazaki K, Makino R, et al. Gastric and intestinal phenotypic marker expression in early differentiated-type tumors of the stomach: Clinicopathologic significance and genetic background. Clin Cancer Res 2006; 12: 6469-79.
    • (2006) Clin Cancer Res , vol.12 , pp. 6469-6479
    • Tajima, Y.1    Yamazaki, K.2    Makino, R.3
  • 74
    • 0032984373 scopus 로고    scopus 로고
    • Origin of microsatellite instability in gastric cancer
    • Halling KC, Harper J, Moskaluk CA, et al. Origin of microsatellite instability in gastric cancer. Am J Pathol 1999; 155: 205-11.
    • (1999) Am J Pathol , vol.155 , pp. 205-211
    • Halling, K.C.1    Harper, J.2    Moskaluk, C.A.3
  • 75
    • 0035836077 scopus 로고    scopus 로고
    • Assessment of markers for the identification of microsatellite instability phenotype in gastric neoplasms
    • Kim HS, Lee BL, Woo DK, Bae SI, Kim WH. Assessment of markers for the identification of microsatellite instability phenotype in gastric neoplasms. Cancer Lett 2001; 164: 61-8.
    • (2001) Cancer Lett , vol.164 , pp. 61-68
    • Kim, H.S.1    Lee, B.L.2    Woo, D.K.3    Bae, S.I.4    Kim, W.H.5
  • 76
    • 0001119305 scopus 로고    scopus 로고
    • HMLH1 promoter methylation and lack of hMLH1 expression in sporadic gastric carcinomas with high-frequency microsatellite instability
    • Leung SY, Yuen ST, Chung LP, Chu KM, Chan AS, Ho JC. hMLH1 promoter methylation and lack of hMLH1 expression in sporadic gastric carcinomas with high-frequency microsatellite instability. Cancer Res 1999; 59: 159-64.
    • (1999) Cancer Res , vol.59 , pp. 159-164
    • Leung, S.Y.1    Yuen, S.T.2    Chung, L.P.3    Chu, K.M.4    Chan, A.S.5    Ho, J.C.6
  • 77
    • 0035012488 scopus 로고    scopus 로고
    • Microsatellite instability of papillary subtype of human gastric adenocarcinoma and hMLH1 promoter hypermethylation in the surrounding mucosa
    • Guo RJ, Arai H, Kitayama Y, et al. Microsatellite instability of papillary subtype of human gastric adenocarcinoma and hMLH1 promoter hypermethylation in the surrounding mucosa. Pathol Int 2001; 51: 240-7.
    • (2001) Pathol Int , vol.51 , pp. 240-247
    • Guo, R.J.1    Arai, H.2    Kitayama, Y.3
  • 78
    • 0343049070 scopus 로고    scopus 로고
    • Microsatellite instability in the adenoma-carcinoma sequence of the stomach
    • Kim HS,Woo DK, Bae SI, Kim YI, Kim WH. Microsatellite instability in the adenoma-carcinoma sequence of the stomach. Lab Invest 2000; 80: 57-64.
    • (2000) Lab Invest , vol.80 , pp. 57-64
    • Kim Hswoo, D.K.1    Bae, S.I.2    Kim, Y.I.3    Kim, W.H.4
  • 79
    • 0031015728 scopus 로고    scopus 로고
    • BAT-26, an indicator of the replication error phenotype in colorectal cancers and cell lines
    • Hoang JM, Cottu PH, Thuille B, Salmon RJ, Thomas G, Hamelin R. BAT-26, an indicator of the replication error phenotype in colorectal cancers and cell lines. Cancer Res 1997; 57: 300-3.
    • (1997) Cancer Res , vol.57 , pp. 300-303
    • Hoang, J.M.1    Cottu, P.H.2    Thuille, B.3    Salmon, R.J.4    Thomas, G.5    Hamelin, R.6
  • 80
    • 0031938045 scopus 로고    scopus 로고
    • Determination of the replication error phenotype in human tumors without the requirement for matching normal DNA by analysis of mononucleotide repeat microsatellites
    • Zhou XP, Hoang JM, Li YJ, et al. Determination of the replication error phenotype in human tumors without the requirement for matching normal DNA by analysis of mononucleotide repeat microsatellites. Genes Chromosomes Cancer 1998; 21: 101-7.
    • (1998) Genes Chromosomes Cancer , vol.21 , pp. 101-107
    • Zhou, X.P.1    Hoang, J.M.2    Li, Y.J.3
  • 81
    • 77956398232 scopus 로고    scopus 로고
    • Microsatellite instability with promoter methylation and silencing of hMLH1 can regionally occur during progression of gastric carcinoma
    • Ling Z, Tanaka A, Li P, et al. Microsatellite instability with promoter methylation and silencing of hMLH1 can regionally occur during progression of gastric carcinoma. Cancer Lett 2010; 297: 244-51.
    • (2010) Cancer Lett , vol.297 , pp. 244-251
    • Ling, Z.1    Tanaka, A.2    Li, P.3
  • 82
    • 84864607654 scopus 로고    scopus 로고
    • Genetic testing by cancer site: Stomach
    • Chun N, Ford J. Genetic testing by cancer site: Stomach. Cancer J 2012; 18: 355-63.
    • (2012) Cancer J , vol.18 , pp. 355-363
    • Chun, N.1    Ford, J.2
  • 83
    • 20444414549 scopus 로고    scopus 로고
    • Microsatellite instability in preneoplastic and neoplastic lesions of the gallbladder
    • Roa J, Roa I, Correa P, et al. Microsatellite instability in preneoplastic and neoplastic lesions of the gallbladder. J Gastroenterol 2005; 40: 79-86.
    • (2005) J Gastroenterol , vol.40 , pp. 79-86
    • Roa, J.1    Roa, I.2    Correa, P.3
  • 84
    • 0035109253 scopus 로고    scopus 로고
    • Infrequent microsatellite instability in biliary tract cancer
    • Suto T, Habano W, Sugai T, et al. Infrequent microsatellite instability in biliary tract cancer. J Surg Oncol 2001; 76: 121-6.
    • (2001) J Surg Oncol , vol.76 , pp. 121-126
    • Suto, T.1    Habano, W.2    Sugai, T.3
  • 85
    • 65449121439 scopus 로고    scopus 로고
    • Histopathologic features and microsatellite instability of cancers of the papilla of vater and their precursor lesions
    • Ruemmele P, Dietmaier W, Terracciano L, et al. Histopathologic features and microsatellite instability of cancers of the papilla of vater and their precursor lesions. Am J Surg Pathol 2009; 33: 691-704.
    • (2009) Am J Surg Pathol , vol.33 , pp. 691-704
    • Ruemmele, P.1    Dietmaier, W.2    Terracciano, L.3
  • 86
    • 34247551329 scopus 로고    scopus 로고
    • Adenocarcinoma of the ampulla of vater: T-stage, chromosome 17p allelic loss, and extended pancreaticoduodenectomy are relevant prognostic factors
    • Iacono C, Verlato G, Zamboni G, et al. Adenocarcinoma of the ampulla of vater: T-stage, chromosome 17p allelic loss, and extended pancreaticoduodenectomy are relevant prognostic factors. J Gastrointest Surg 2007; 11: 578-88.
    • (2007) J Gastrointest Surg , vol.11 , pp. 578-588
    • Iacono, C.1    Verlato, G.2    Zamboni, G.3
  • 87
    • 34548357125 scopus 로고    scopus 로고
    • Prognostic factors for ampullary adenocarcinomas: Tumor stage, tumor histology, tumor location, immunohistochemistry and microsatellite instability
    • Sessa F, Furlan D, Zampatti C, Carnevali I, Franzi F, Capella C. Prognostic factors for ampullary adenocarcinomas: Tumor stage, tumor histology, tumor location, immunohistochemistry and microsatellite instability. Virchows Arch 2007; 451: 649-57.
    • (2007) Virchows Arch , vol.451 , pp. 649-657
    • Sessa, F.1    Furlan, D.2    Zampatti, C.3    Carnevali, I.4    Franzi, F.5    Capella, C.6
  • 88
    • 0034029111 scopus 로고    scopus 로고
    • Cancer of the ampulla of vater: Chromosome 17p allelic loss is associated with poor prognosis
    • Scarpa A, Di Pace C, Talamini G, et al. Cancer of the ampulla of vater: Chromosome 17p allelic loss is associated with poor prognosis. Gut 2000; 46: 842-8.
    • (2000) Gut , vol.46 , pp. 842-848
    • Scarpa, A.1    Di Pace, C.2    Talamini, G.3
  • 89
    • 0030843014 scopus 로고    scopus 로고
    • Cancers of the papilla of vater: Mutator phenotype is associated with good prognosis
    • Achille A, Biasi MO, Zamboni G, et al. Cancers of the papilla of vater: Mutator phenotype is associated with good prognosis. Clin Cancer Res 1997; 3: 1841-7.
    • (1997) Clin Cancer Res , vol.3 , pp. 1841-1847
    • Achille, A.1    Biasi, M.O.2    Zamboni, G.3
  • 90
    • 77951917844 scopus 로고    scopus 로고
    • DNA mismatch repair deficiency in ampullary carcinoma: A morphologic and immunohistochemical study of 54 cases
    • Agaram N, Shia J, Tang L, Klimstra D. DNA mismatch repair deficiency in ampullary carcinoma: A morphologic and immunohistochemical study of 54 cases. Am J Clin Pathol 2010; 133: 772-80.
    • (2010) Am J Clin Pathol , vol.133 , pp. 772-780
    • Agaram, N.1    Shia, J.2    Tang, L.3    Klimstra, D.4
  • 91
    • 85047687343 scopus 로고    scopus 로고
    • Microsatellite instability in chronic cholecystitis is indicative of an early stage in gallbladder carcinogenesis
    • Yanagisawa N, Mikami T, Yamashita K, Okayasu I. Microsatellite instability in chronic cholecystitis is indicative of an early stage in gallbladder carcinogenesis. Am J Clin Pathol 2003; 120: 413-7.
    • (2003) Am J Clin Pathol , vol.120 , pp. 413-417
    • Yanagisawa, N.1    Mikami, T.2    Yamashita, K.3    Okayasu, I.4
  • 92
    • 0032813097 scopus 로고    scopus 로고
    • Analysis of microsatellite instability, TGF-beta type II receptor gene mutations and hMSH2 and hMLH1 allele losses in pancreaticobiliary maljunction-associated biliary tract tumors
    • Nagai M, Kawarada Y, Watanabe M, et al. Analysis of microsatellite instability, TGF-beta type II receptor gene mutations and hMSH2 and hMLH1 allele losses in pancreaticobiliary maljunction-associated biliary tract tumors. Anticancer Res 1999; 19: 1765-8.
    • (1999) Anticancer Res , vol.19 , pp. 1765-1768
    • Nagai, M.1    Kawarada, Y.2    Watanabe, M.3
  • 93
    • 0036369204 scopus 로고    scopus 로고
    • Clinical and genetic analysis of noncancerous and cancerous biliary epithelium in patients with pancreaticobiliary maljunction
    • Nagai M, Watanabe M, Iwase T, Yamao K, Isaji S. Clinical and genetic analysis of noncancerous and cancerous biliary epithelium in patients with pancreaticobiliary maljunction. World J Surg 2002; 26: 91-8.
    • (2002) World J Surg , vol.26 , pp. 91-98
    • Nagai, M.1    Watanabe, M.2    Iwase, T.3    Yamao, K.4    Isaji, S.5
  • 95
    • 79958798502 scopus 로고    scopus 로고
    • Frequency of genetic alterations observed in cell cycle regulatory proteins and microsatellite instability in gallbladder adenocarcinoma: A translational perspective
    • Mishra P, Raghuram G, Jatawa S, Bhargava A, Varshney S. Frequency of genetic alterations observed in cell cycle regulatory proteins and microsatellite instability in gallbladder adenocarcinoma: A translational perspective. Asian Pac J Cancer Prev 2011; 12: 573-4.
    • (2011) Asian Pac J Cancer Prev , vol.12 , pp. 573-574
    • Mishra, P.1    Raghuram, G.2    Jatawa, S.3    Bhargava, A.4    Varshney, S.5
  • 96
    • 0035839308 scopus 로고    scopus 로고
    • Genetic alterations in gallbladder adenoma, dysplasia and carcinoma
    • Kim YT, Kim J, Jang YH, et al. Genetic alterations in gallbladder adenoma, dysplasia and carcinoma. Cancer Lett 2001; 169: 59-68.
    • (2001) Cancer Lett , vol.169 , pp. 59-68
    • Kim, Y.T.1    Kim, J.2    Jang, Y.H.3
  • 97
    • 0344132588 scopus 로고    scopus 로고
    • Loss of heterozygosity in dysplasia and carcinoma of the gallbladder
    • Chang HJ, KimSW, KimYT, KimWH. Loss of heterozygosity in dysplasia and carcinoma of the gallbladder. Mod Pathol 1999; 12: 763-9.
    • (1999) Mod Pathol , vol.12 , pp. 763-769
    • Chang, H.J.1    Kim Kim, S.W.Y.T.2    Kim, W.H.3
  • 98
    • 0033760762 scopus 로고    scopus 로고
    • Microsatellite instability in gallbladder carcinoma: Two independent genetic pathways of gallbladder carcinogenesis
    • Yoshida T, Sugai T, Habano W, et al. Microsatellite instability in gallbladder carcinoma: Two independent genetic pathways of gallbladder carcinogenesis. J Gastroenterol 2000; 35: 768-74.
    • (2000) J Gastroenterol , vol.35 , pp. 768-774
    • Yoshida, T.1    Sugai, T.2    Habano, W.3
  • 99
    • 0036793788 scopus 로고    scopus 로고
    • K-ras mutation, p53 overexpression, and microsatellite instability in biliary tract cancers: A population-based study in China
    • Rashid A, Ueki T, Gao Y, et al. K-ras mutation, p53 overexpression, and microsatellite instability in biliary tract cancers: A population-based study in China. Clin Cancer Res 2002; 8: 3156-63.
    • (2002) Clin Cancer Res , vol.8 , pp. 3156-3163
    • Rashid, A.1    Ueki, T.2    Gao, Y.3
  • 100
    • 39849090322 scopus 로고    scopus 로고
    • Genetic changes of p53, K-ras, and microsatellite instability in gallbladder carcinoma in high-incidence areas of Japan and Hungary
    • Nagahashi M, Ajioka Y, Lang I, et al. Genetic changes of p53, K-ras, and microsatellite instability in gallbladder carcinoma in high-incidence areas of Japan and Hungary. World J Gastroenterol 2008; 14: 70-5.
    • (2008) World J Gastroenterol , vol.14 , pp. 70-75
    • Nagahashi, M.1    Ajioka, Y.2    Lang, I.3
  • 101
    • 0034775234 scopus 로고    scopus 로고
    • Genetic alterations involved in the development of gallbladder carcinomas from Greek patients
    • Saetta A, Lazaris AC, Michalopoulos NV, Davaris PS. Genetic alterations involved in the development of gallbladder carcinomas from Greek patients. Hepatogastroenterology 2001; 48: 1284-8.
    • (2001) Hepatogastroenterology , vol.48 , pp. 1284-1288
    • Saetta, A.1    Lazaris, A.C.2    Michalopoulos, N.V.3    Davaris, P.S.4
  • 102
    • 0344530608 scopus 로고    scopus 로고
    • Evaluation of BAT-26 as an indicator of microsatellite instability in gallbladder carcinomas
    • Saetta A, Koilakou S, Michalopoulos N, Davaris P. Evaluation of BAT-26 as an indicator of microsatellite instability in gallbladder carcinomas. Hepatogastroenterology 2003; 50: 1799-802.
    • (2003) Hepatogastroenterology , vol.50 , pp. 1799-1802
    • Saetta, A.1    Koilakou, S.2    Michalopoulos, N.3    Davaris, P.4
  • 103
    • 4544385478 scopus 로고    scopus 로고
    • Mutational analysis of BRAF in gallbladder carcinomas in association with K-ras and p53 mutations and microsatellite instability
    • Saetta A, Papanastasiou P, Michalopoulos N, et al. Mutational analysis of BRAF in gallbladder carcinomas in association with K-ras and p53 mutations and microsatellite instability. Virchows Arch 2004; 445: 179- 82.
    • (2004) Virchows Arch , vol.445 , pp. 179-182
    • Saetta, A.1    Papanastasiou, P.2    Michalopoulos, N.3
  • 104
    • 29244451068 scopus 로고    scopus 로고
    • High-level microsatellite instability is not involved in gallbladder carcinogenesis
    • Saetta A, Gigelou F, Papanastasiou P, et al. High-level microsatellite instability is not involved in gallbladder carcinogenesis. Exp Mol Pathol 2006; 80: 67-71.
    • (2006) Exp Mol Pathol , vol.80 , pp. 67-71
    • Saetta, A.1    Gigelou, F.2    Papanastasiou, P.3
  • 105
    • 0038638906 scopus 로고    scopus 로고
    • Epigenetic and genetic alterations in duodenal carcinomas are distinct from biliary and ampullary carcinomas
    • Kim S, Chan A, Wu T, Issa J, Hamilton S, Rashid A. Epigenetic and genetic alterations in duodenal carcinomas are distinct from biliary and ampullary carcinomas. Gastroenterology 2003; 124: 1300-10.
    • (2003) Gastroenterology , vol.124 , pp. 1300-1310
    • Kim, S.1    Chan, A.2    Wu, T.3    Issa, J.4    Hamilton, S.5    Rashid, A.6
  • 106
    • 18744414743 scopus 로고    scopus 로고
    • Microsatellite instability in intraductal papillary neoplasms of the biliary tract
    • Abraham S, Lee J, Boitnott J, Argani P, Furth E, Wu T. Microsatellite instability in intraductal papillary neoplasms of the biliary tract. Mod Pathol 2002; 15: 1309-17.
    • (2002) Mod Pathol , vol.15 , pp. 1309-1317
    • Abraham, S.1    Lee, J.2    Boitnott, J.3    Argani, P.4    Furth, E.5    Wu, T.6
  • 107
    • 0242406852 scopus 로고    scopus 로고
    • Lack of microsatellite instability in neoplasms of ampulla of vater
    • Park S, Kim S, Darwish N, Kim W. Lack of microsatellite instability in neoplasms of ampulla of vater. Pathol Int 2003; 53: 667-70.
    • (2003) Pathol Int , vol.53 , pp. 667-670
    • Park, S.1    Kim, S.2    Darwish, N.3    Kim, W.4
  • 108
    • 0031746171 scopus 로고    scopus 로고
    • Genetic instability and mutation of the TGF-beta-receptor-II gene in ampullary carcinomas
    • Imai Y, Tsurutani N, Oda H, Inoue T, Ishikawa T. Genetic instability and mutation of the TGF-beta-receptor-II gene in ampullary carcinomas. Int J Cancer 1998; 76: 407-11.
    • (1998) Int J Cancer , vol.76 , pp. 407-411
    • Imai, Y.1    Tsurutani, N.2    Oda, H.3    Inoue, T.4    Ishikawa, T.5
  • 109
    • 17644430199 scopus 로고    scopus 로고
    • Pancreatic adenocarcinomas with DNA replication errors (RER) are associated with wild-type K-ras and characteristic histopathology. Poor differentiation, a syncytial growth pattern, and pushing borders suggest RER
    • Goggins M, Offerhaus GJ, Hilgers W, et al. Pancreatic adenocarcinomas with DNA replication errors (RER) are associated with wild-type K-ras and characteristic histopathology. poor differentiation, a syncytial growth pattern, and pushing borders suggest RER. Am J Pathol 1998; 152: 1501-7.
    • (1998) Am J Pathol , vol.152 , pp. 1501-1507
    • Goggins, M.1    Offerhaus, G.J.2    Hilgers, W.3
  • 110
    • 1542787474 scopus 로고    scopus 로고
    • Negative hMSH2 protein expression in pancreatic carcinoma may predict a better prognosis of patients
    • Nakata B, Wang Y, Yashiro M, et al. Negative hMSH2 protein expression in pancreatic carcinoma may predict a better prognosis of patients. Oncol Rep 2003; 10: 997-1000.
    • (2003) Oncol Rep , vol.10 , pp. 997-1000
    • Nakata, B.1    Wang, Y.2    Yashiro, M.3
  • 111
    • 0035300547 scopus 로고    scopus 로고
    • Genetic and clinical features of human pancreatic ductal adenocarcinomas with widespread microsatellite instability
    • Yamamoto H, Itoh F, Nakamura H, et al. Genetic and clinical features of human pancreatic ductal adenocarcinomas with widespread microsatellite instability. Cancer Res 2001; 61: 3139-44.
    • (2001) Cancer Res , vol.61 , pp. 3139-3144
    • Yamamoto, H.1    Itoh, F.2    Nakamura, H.3
  • 113
    • 70350733425 scopus 로고    scopus 로고
    • Risk of pancreatic cancer in families with Lynch syndrome
    • Kastrinos F, Mukherjee B, Tayob N, et al. Risk of pancreatic cancer in families with Lynch syndrome. JAMA 2009; 302: 1790-5.
    • (2009) JAMA , vol.302 , pp. 1790-1795
    • Kastrinos, F.1    Mukherjee, B.2    Tayob, N.3
  • 114
    • 45749151120 scopus 로고    scopus 로고
    • Gene-related cancer spectrum in families with hereditary non-polyposis colorectal cancer (HNPCC)
    • Geary J, Sasieni P, Houlston R, et al. Gene-related cancer spectrum in families with hereditary non-polyposis colorectal cancer (HNPCC). Fam Cancer 2008; 7: 163-72.
    • (2008) Fam Cancer , vol.7 , pp. 163-172
    • Geary, J.1    Sasieni, P.2    Houlston, R.3
  • 115
    • 33750083369 scopus 로고    scopus 로고
    • Medullary carcinoma of the pancreas in a man with hereditary nonpolyposis colorectal cancer due to a mutation of the MSH2 mismatch repair gene
    • Banville N, Geraghty R, Fox E, et al. Medullary carcinoma of the pancreas in a man with hereditary nonpolyposis colorectal cancer due to a mutation of the MSH2 mismatch repair gene. Hum Pathol 2006; 37: 1498-502.
    • (2006) Hum Pathol , vol.37 , pp. 1498-1502
    • Banville, N.1    Geraghty, R.2    Fox, E.3
  • 116
    • 0033847858 scopus 로고    scopus 로고
    • Genetic, immunohistochemical, and clinical features of medullary carcinoma of the pancreas: A newly described and characterized entity
    • Wilentz RE, Goggins M, Redston M, et al. Genetic, immunohistochemical, and clinical features of medullary carcinoma of the pancreas: A newly described and characterized entity. Am J Pathol 2000; 156: 1641-51.
    • (2000) Am J Pathol , vol.156 , pp. 1641-1651
    • Wilentz, R.E.1    Goggins, M.2    Redston, M.3
  • 117
    • 84866662081 scopus 로고    scopus 로고
    • Irrelevance of microsatellite instability in the epidemiology of sporadic pancreatic ductal adenocarcinoma
    • Laghi L, Beghelli S, Spinelli A, et al. Irrelevance of microsatellite instability in the epidemiology of sporadic pancreatic ductal adenocarcinoma. PLoS One 2012; 7: e46002-146002.
    • (2012) PLoS One , vol.7
    • Laghi, L.1    Beghelli, S.2    Spinelli, A.3
  • 118
    • 0031981181 scopus 로고    scopus 로고
    • Novel mutations in the polyadenine tract of the transforming growth factor beta type II receptor gene are found in a subpopulation of human pancreatic adenocarcinomas
    • Venkatasubbarao K, Ahmed MM, Swiderski C, et al. Novel mutations in the polyadenine tract of the transforming growth factor beta type II receptor gene are found in a subpopulation of human pancreatic adenocarcinomas. Genes Chromosomes Cancer 1998; 22: 138-44.
    • (1998) Genes Chromosomes Cancer , vol.22 , pp. 138-144
    • Venkatasubbarao, K.1    Ahmed, M.M.2    Swiderski, C.3
  • 119
    • 19944390234 scopus 로고    scopus 로고
    • Defective DNA mismatch repair in long-term (> or = years) survivors with pancreatic cancer
    • Maple J, Smyrk T, Boardman L, Johnson R, Thibodeau S, Chari S. Defective DNA mismatch repair in long-term (> or = years) survivors with pancreatic cancer. Pancreatology 2005; 5: 220-7.
    • (2005) Pancreatology , vol.5 , pp. 220-227
    • Maple, J.1    Smyrk, T.2    Boardman, L.3    Johnson, R.4    Thibodeau, S.5    Chari, S.6
  • 120
    • 0038795408 scopus 로고    scopus 로고
    • Pancreatic mucinous noncystic (colloid) carcinomas and intraductal papillary mucinous carcinomas are usually microsatellite stable
    • Luttges J, Beyser K, Pust S, Paulus A, Ruschoff J, Kloppel G. Pancreatic mucinous noncystic (colloid) carcinomas and intraductal papillary mucinous carcinomas are usually microsatellite stable. Mod Pathol 2003; 16: 537-42.
    • (2003) Mod Pathol , vol.16 , pp. 537-542
    • Luttges, J.1    Beyser, K.2    Pust, S.3    Paulus, A.4    Ruschoff, J.5    Kloppel, G.6
  • 121
    • 0029853786 scopus 로고    scopus 로고
    • The somatic mutation frequency of the transforming growth factor beta receptor type II gene varies widely among different cancers with microsatellite instability
    • Abe T, Ouyang H, Migita T, et al. The somatic mutation frequency of the transforming growth factor beta receptor type II gene varies widely among different cancers with microsatellite instability. Eur J Surg Oncol 1996; 22: 474-7.
    • (1996) Eur J Surg Oncol , vol.22 , pp. 474-477
    • Abe, T.1    Ouyang, H.2    Migita, T.3
  • 122
    • 58249136623 scopus 로고    scopus 로고
    • Simulation-based analyses reveal stable microsatellite sequences in human pancreatic cancer
    • Fujii K, Miyashita K, Yamada Y, et al. Simulation-based analyses reveal stable microsatellite sequences in human pancreatic cancer. Cancer Genet Cytogenet 2009; 189: 5-14.
    • (2009) Cancer Genet Cytogenet , vol.189 , pp. 5-14
    • Fujii, K.1    Miyashita, K.2    Yamada, Y.3
  • 123
    • 0036023411 scopus 로고    scopus 로고
    • Prognostic value of microsatellite instability in resectable pancreatic cancer
    • Nakata B, Wang Y, Yashiro M, et al. Prognostic value of microsatellite instability in resectable pancreatic cancer. Clin Cancer Res 2002; 8: 2536-40.
    • (2002) Clin Cancer Res , vol.8 , pp. 2536-2540
    • Nakata, B.1    Wang, Y.2    Yashiro, M.3
  • 124
    • 14444287748 scopus 로고    scopus 로고
    • The insulin-like growth factor II receptor gene is mutated in genetically unstable cancers of the endometrium, stomach, and colorectum
    • Ouyang H, Shiwaku HO, Hagiwara H, et al. The insulin-like growth factor II receptor gene is mutated in genetically unstable cancers of the endometrium, stomach, and colorectum. Cancer Res 1997; 57: 1851-4.
    • (1997) Cancer Res , vol.57 , pp. 1851-1854
    • Ouyang, H.1    Shiwaku, H.O.2    Hagiwara, H.3
  • 125
    • 0029023147 scopus 로고
    • Microsatellite instability and K-ras mutations associated with pancreatic adenocarcinoma and pancreatitis
    • Brentnall TA, Chen R, Lee JG, et al. Microsatellite instability and K-ras mutations associated with pancreatic adenocarcinoma and pancreatitis. Cancer Res 1995; 55: 4264-7.
    • (1995) Cancer Res , vol.55 , pp. 4264-4267
    • Brentnall, T.A.1    Chen, R.2    Lee, J.G.3
  • 126
    • 80052400707 scopus 로고    scopus 로고
    • Analysis of LKB1 mutations and other molecular alterations in pancreatic acinar cell carcinoma
    • deWilde R, Ottenhof N, Jansen M, et al. Analysis of LKB1 mutations and other molecular alterations in pancreatic acinar cell carcinoma. Mod Pathol 2011; 24: 1229-36.
    • (2011) Mod Pathol , vol.24 , pp. 1229-1236
    • Dewilde, R.1    Ottenhof, N.2    Jansen, M.3
  • 127
    • 0036120621 scopus 로고    scopus 로고
    • Genetic and immunohistochemical analysis of pancreatic acinar cell carcinoma: Frequent allelic loss on chromosome 11p and alterations in the APC/beta-catenin pathway
    • Abraham S, Wu T, Hruban R, et al. Genetic and immunohistochemical analysis of pancreatic acinar cell carcinoma: Frequent allelic loss on chromosome 11p and alterations in the APC/beta-catenin pathway. Am J Pathol 2002; 160: 953-62.
    • (2002) Am J Pathol , vol.160 , pp. 953-962
    • Abraham, S.1    Wu, T.2    Hruban, R.3
  • 128
    • 74249088974 scopus 로고    scopus 로고
    • Immunophenotype and molecular characterisation of adenocarcinoma of the small intestine
    • Overman MJ, Pozadzides J, Kopetz S, et al. Immunophenotype and molecular characterisation of adenocarcinoma of the small intestine. Br J Cancer 2010; 102: 144-50.
    • (2010) Br J Cancer , vol.102 , pp. 144-150
    • Overman, M.J.1    Pozadzides, J.2    Kopetz, S.3
  • 129
    • 75849130566 scopus 로고    scopus 로고
    • Coding microsatellite instability analysis in microsatellite unstable small intestinal adenocarcinomas identifies MARCKS as a common target of inactivation
    • Michel S, Kloor M, Singh S, et al. Coding microsatellite instability analysis in microsatellite unstable small intestinal adenocarcinomas identifies MARCKS as a common target of inactivation. Mol Carcinog 2010; 49: 175-82.
    • (2010) Mol Carcinog , vol.49 , pp. 175-182
    • Michel, S.1    Kloor, M.2    Singh, S.3
  • 130
    • 9144252090 scopus 로고    scopus 로고
    • Prognostic significance of microsatellite instability in curatively resected adenocarcinoma of the small intestine
    • Brueckl W, Heinze E, Milsmann C, et al. Prognostic significance of microsatellite instability in curatively resected adenocarcinoma of the small intestine. Cancer Lett 2004; 203: 181-90.
    • (2004) Cancer Lett , vol.203 , pp. 181-190
    • Brueckl, W.1    Heinze, E.2    Milsmann, C.3
  • 131
    • 0031886529 scopus 로고    scopus 로고
    • Molecular pathogenesis of sporadic duodenal cancer
    • Achille A, Baron A, Zamboni G, et al. Molecular pathogenesis of sporadic duodenal cancer. Br J Cancer 1998; 77: 760-5.
    • (1998) Br J Cancer , vol.77 , pp. 760-765
    • Achille, A.1    Baron, A.2    Zamboni, G.3
  • 132
    • 4944262850 scopus 로고    scopus 로고
    • The role of defective mismatch repair in small bowel adenocarcinoma in celiac disease
    • Potter DD, Murray J, Donohue J, et al. The role of defective mismatch repair in small bowel adenocarcinoma in celiac disease. Cancer Res 2004; 64: 7073-7.
    • (2004) Cancer Res , vol.64 , pp. 7073-7077
    • Potter, D.D.1    Murray, J.2    Donohue, J.3
  • 134
    • 84870747205 scopus 로고    scopus 로고
    • Risks of less common cancers in proven mutation carriers with Lynch syndrome
    • Engel C, Loeffler M, Steinke V, et al. Risks of less common cancers in proven mutation carriers with Lynch syndrome. J Clin Oncol 2012; 30: 4409-15.
    • (2012) J Clin Oncol , vol.30 , pp. 4409-4415
    • Engel, C.1    Loeffler, M.2    Steinke, V.3
  • 135
    • 0029862873 scopus 로고    scopus 로고
    • Cancer risk in families with hereditary nonpolyposis colorectal cancer diagnosed by mutation analysis
    • Vasen HF, Wijnen JT, Menko FH, et al. Cancer risk in families with hereditary nonpolyposis colorectal cancer diagnosed by mutation analysis. Gastroenterology 1996; 110: 1020-7.
    • (1996) Gastroenterology , vol.110 , pp. 1020-1027
    • Vasen, H.F.1    Wijnen, J.T.2    Menko, F.H.3
  • 136
    • 0032527946 scopus 로고    scopus 로고
    • Characteristics of small bowel carcinoma in hereditary nonpolyposis colorectal carcinoma. International collaborative group on HNPCC
    • Rodriguez Bigas MA, Vasen HF, Lynch HT, et al. Characteristics of small bowel carcinoma in hereditary nonpolyposis colorectal carcinoma. International collaborative group on HNPCC. Cancer 1998; 83: 240-4.
    • (1998) Cancer , vol.83 , pp. 240-244
    • Rodriguez Bigas, M.A.1    Vasen, H.F.2    Lynch, H.T.3
  • 137
    • 2542476370 scopus 로고    scopus 로고
    • Reduced expression of cytokeratin 20 in colorectal carcinomas with high levels of microsatellite instability
    • McGregor D,Wu T, Rashid A, Luthra R, Hamilton S. Reduced expression of cytokeratin 20 in colorectal carcinomas with high levels of microsatellite instability. Am J Surg Pathol 2004; 28: 712-8.
    • (2004) Am J Surg Pathol , vol.28 , pp. 712-718
    • McGregor Dwu, T.1    Rashid, A.2    Luthra, R.3    Hamilton, S.4
  • 138
    • 0033732278 scopus 로고    scopus 로고
    • Combination analysis of genetic alterations and cell proliferation in small intestinal carcinomas
    • Muneyuki T, Watanabe M, Yamanaka M, Isaji S, Kawarada Y, Yatani R. Combination analysis of genetic alterations and cell proliferation in small intestinal carcinomas. Dig Dis Sci 2000; 45: 2022-8.
    • (2000) Dig Dis Sci , vol.45 , pp. 2022-2028
    • Muneyuki, T.1    Watanabe, M.2    Yamanaka, M.3    Isaji, S.4    Kawarada, Y.5    Yatani, R.6
  • 140
    • 84872057417 scopus 로고    scopus 로고
    • Expression of hMLH1, hMSH2 and hMSH6 in small intestinal carcinomas
    • Gu M, Bae Y, Kim A, et al. Expression of hMLH1, hMSH2 and hMSH6 in small intestinal carcinomas. Hepatogastroenterology 2012; 59: 2228-32.
    • (2012) Hepatogastroenterology , vol.59 , pp. 2228-2232
    • Gu, M.1    Bae, Y.2    Kim, A.3
  • 141
    • 0037443658 scopus 로고    scopus 로고
    • Microsatellite instability and expression of MLH1 and MSH2 in carcinomas of the small intestine
    • Planck M, Ericson K, Piotrowska Z, Halvarsson B, Rambech E, Nilbert M. Microsatellite instability and expression of MLH1 and MSH2 in carcinomas of the small intestine. Cancer 2003; 97: 1551-7.
    • (2003) Cancer , vol.97 , pp. 1551-1557
    • Planck, M.1    Ericson, K.2    Piotrowska, Z.3    Halvarsson, B.4    Rambech, E.5    Nilbert, M.6
  • 142
    • 0037012010 scopus 로고    scopus 로고
    • Genetics of adenocarcinomas of the small intestine: Frequent deletions at chromosome 18q and mutations of theSMAD4 gene
    • Blaker H, von Herbay A, Penzel R, Gross S, Otto H. Genetics of adenocarcinomas of the small intestine: Frequent deletions at chromosome 18q and mutations of theSMAD4 gene. Oncogene 2002; 21: 158-64.
    • (2002) Oncogene , vol.21 , pp. 158-164
    • Blaker, H.1    Von Herbay, A.2    Penzel, R.3    Gross, S.4    Otto, H.5
  • 143
    • 79953309255 scopus 로고    scopus 로고
    • Genetics and epigenetics of small bowel adenocarcinoma: The interactions of CIN, MSI, and CIMP
    • Warth A, Kloor M, Schirmacher P, Blaker H. Genetics and epigenetics of small bowel adenocarcinoma: The interactions of CIN, MSI, and CIMP. Mod Pathol 2011; 24: 564-70.
    • (2011) Mod Pathol , vol.24 , pp. 564-570
    • Warth, A.1    Kloor, M.2    Schirmacher, P.3    Blaker, H.4
  • 144
    • 0036155981 scopus 로고    scopus 로고
    • An insight into the genetic pathway of adenocarcinoma of the small intestine
    • Wheeler JMD, Warren BF, Mortensen NJM, et al. An insight into the genetic pathway of adenocarcinoma of the small intestine. Gut 2002; 50: 218-23.
    • (2002) Gut , vol.50 , pp. 218-223
    • Wheeler, J.M.D.1    Warren, B.F.2    Mortensen, N.J.M.3
  • 145
    • 77649124326 scopus 로고    scopus 로고
    • High-resolution array comparative genomic hybridization in sporadic and celiac disease-related small bowel adenocarcinomas
    • Diosdado B, Buffart T, Watkins R, et al. High-resolution array comparative genomic hybridization in sporadic and celiac disease-related small bowel adenocarcinomas. Clin Cancer Res 2010; 16: 1391-401.
    • (2010) Clin Cancer Res , vol.16 , pp. 1391-1401
    • Diosdado, B.1    Buffart, T.2    Watkins, R.3
  • 146
    • 78649410451 scopus 로고    scopus 로고
    • Small bowel adenocarcinomas in celiac disease follow the CIM-MSI pathway
    • Bergmann F, Singh S, Michel S, et al. Small bowel adenocarcinomas in celiac disease follow the CIM-MSI pathway. Oncol Rep 2010; 24: 1535-9.
    • (2010) Oncol Rep , vol.24 , pp. 1535-1539
    • Bergmann, F.1    Singh, S.2    Michel, S.3
  • 147
    • 0031001501 scopus 로고    scopus 로고
    • Genetic alterations in sporadic and Crohn'sassociated adenocarcinomas of the small intestine
    • Rashid A, Hamilton SR. Genetic alterations in sporadic and Crohn'sassociated adenocarcinomas of the small intestine. Gastroenterology 1997; 113: 127-35.
    • (1997) Gastroenterology , vol.113 , pp. 127-135
    • Rashid, A.1    Hamilton, S.R.2
  • 148
    • 24944490356 scopus 로고    scopus 로고
    • T25 repeat in the 3' untranslated region of the CASP2 gene: A sensitive and specific marker for microsatellite instability in colorectal cancer
    • Findeisen P, Kloor M, Merx S, et al. T25 repeat in the 3' untranslated region of the CASP2 gene: A sensitive and specific marker for microsatellite instability in colorectal cancer. Cancer Res 2005; 65: 8072-8.
    • (2005) Cancer Res , vol.65 , pp. 8072-8078
    • Findeisen, P.1    Kloor, M.2    Merx, S.3
  • 149
    • 33645305955 scopus 로고    scopus 로고
    • Immunohistochemical investigation of tumorigenic pathways in small intestinal adenocarcinoma: A comparison with colorectal adenocarcinoma
    • Zhang M, Chen Z, Wang H. Immunohistochemical investigation of tumorigenic pathways in small intestinal adenocarcinoma: A comparison with colorectal adenocarcinoma. Mod Pathol 2006; 19: 573-80.
    • (2006) Mod Pathol , vol.19 , pp. 573-580
    • Zhang, M.1    Chen, Z.2    Wang, H.3
  • 150
    • 33745693216 scopus 로고    scopus 로고
    • Hypermethylation of hMLH1, HPP1, p14(ARF), p16(INK4A) and APC in primary adenocarcinomas of the small bowel
    • Brucher BLDM, Geddert H, Langner C, et al. Hypermethylation of hMLH1, HPP1, p14(ARF), p16(INK4A) and APC in primary adenocarcinomas of the small bowel. Int J Cancer 2006; 119: 1298-302.
    • (2006) Int J Cancer , vol.119 , pp. 1298-1302
    • Bldm, B.1    Geddert, H.2    Langner, C.3
  • 151
    • 33646134367 scopus 로고    scopus 로고
    • Small bowel adenocarcinoma with high levels of microsatellite instability in Crohn's disease
    • Chan RCF, Katelaris P, Stewart P, Lin BPC. Small bowel adenocarcinoma with high levels of microsatellite instability in Crohn's disease. Hum Pathol 2006; 37: 631-4.
    • (2006) Hum Pathol , vol.37 , pp. 631-634
    • Chan, R.C.F.1    Katelaris, P.2    Stewart, P.3    Lin, B.P.C.4


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