Evaluation of BAT-26 as an Indicator of Microsatellite Instability in Gallbladder Carcinomas

Hepato-Gastroenterology

Volumn 50, Issue 54, 2003, Pages 1799-1802

  Saetta, Angelica ^a,b   Koilakou, Stavroula V ^a   Michalopoulos, Nikolaos V ^a   Davaris, Panayiotis S ^a  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^b NONE   (Greece)

Author keywords

BAT 26; bax; Gallbladder cancer; k ras; MSI; p53; PCR; TGF RII gene

Indexed keywords

BAT 26 NUCLEOTIDE; BIOLOGICAL MARKER; NUCLEOTIDE DERIVATIVE; POLYACRYLAMIDE GEL; PROTEIN BAX; PROTEIN P53; RAS PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CARCINOGENESIS; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; CORRELATION ANALYSIS; ELECTROPHORESIS; FEMALE; GALLBLADDER CARCINOMA; GREECE; HUMAN; MALE; MICROSATELLITE INSTABILITY; PATHOLOGY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

ADENOCARCINOMA; ADENOCARCINOMA, PAPILLARY; AGED; AGED, 80 AND OVER; BASE PAIR MISMATCH; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; CHROMOSOMAL INSTABILITY; CHROMOSOME DELETION; COLONIC NEOPLASMS; DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; DNA-BINDING PROTEINS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; GALLBLADDER; GALLBLADDER NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, RAS; HUMANS; INTRONS; MALE; MICROSATELLITE REPEATS; MIDDLE AGED; MUTS HOMOLOG 2 PROTEIN; POLYMERASE CHAIN REACTION; PROGNOSIS; PROTO-ONCOGENE PROTEINS; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0344530608     PISSN: 01726390     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Pitt HA, Dooley WC, Yeo CJ, Cameron JL: Malignancies of the biliary tree. Curr Prob Surg 1995; 32:1-90.
2. Silverberg E, Lubera JA: Cancer Statistics 1989. CA-Cancer J Clin 1989; 39:3-20.
3. Chianale J, del Pino G, Nervi F: Increasing gall-bladder cancer mortality rate during the last decade in Chile, a high-risk area. Int J Cancer 1990; 46:1131-1133.
4. Dowling PG, Kelly KJ: The histogenesis of adenocarcinoma of the gallbladder. Cancer 1986; 58:1702-1708.
5. Itoi T, Watanabe H, Ajioka Y, Oohashi Y, Takel K, Nishikura K, Nakamura Y, Horil A, Saito T: APC, K-ras codon 12 mutations and p53 gene expression in carcinoma and adenoma of the gall-bladder suggest two genetic pathways in gall-bladder carcinogenesis. Pathol Int 1996; 46:333-340.
6. Kimura K, Ohto M, Saisho H, Unozawa T, Tsuchiya Y, Morita M, Ebara M, Matsutani S, Okuda K: Association of gallbladder carcinoma and anomalous pancreaticobiliary ductal union. Gastroenterology 1985; 89:1258-1265.
7. Mori K, Akimoto R, Kanno M, Kamata T, Hirono Y, Matsumura A: Anomalous union of the pancreaticobiliary ductal system without dilation of the common bile duct or tumor: case reports and literature review. Hepatogastroenterology 1999; 46:142-147.
8. Hanada K, Itoh M, Fujii K, Tsuchida M, Hirata T, Iwao N, Eguchi T, Sasaki K, Matsubara K, Kajiyama G: K-ras and p53 mutations in stage I gallbladder carcinoma with an anomalous junction of the pancreaticobiliary duct. Cancer 1996; 77:452-480.
9. Masuhara S, Kasuya K, Aoki T, Yoshimatsu A, Tsuchida A, Koyanagi Y: Relation between K-ras codon 12 mutation and p53 protein overexpression in gallbladder cancer and biliary ductal epithelia in patients with pancreaticobiliary maljunction. J Hepatobiliary Pancreat Surg 2000; 7:198-205.
10. Matsubara T, Funabiki T, Jinno O, Sakurai Y, Hasegawa S, Imazu H, Ochiai M: p53 Gene mutations and overexpression of p53 product in cancerous and non-cancerous biliary epithelium in patients with pancreaticobiliary maljunction. J Hepatobiliary Pancreat Surg 1999; 6:286-293.
11. Samowitz WS, Slattery ML, Potter JD, Leppert MF: BAT-26 and BAT-40 instability in colorectal adenomas and carcinomas and germline polymorphisms. Am J Pathol 1999; 154:1637-1641.
12. Zhou XP, Hoang JM, Li YJ, Seruca R, Carneiro F, Sobrinho-Simoes M, Lothe RA, Gleeson CM, Russel SE, Muzeau F, Flejou JF, Hoang-Xuan K, Lidereau R, Thomas G, Hamelin R: Determination of the replication error phenotype in human tumors without the requirement for matching normal DNA by analysis of mononucleotide repeat microsatellites. Gene Chromosome Canc 1998; 21:101-107.
13. Hoang JM, Cottu PH, Thuille B, Salmon RJ, Thomas G, Hamelin R: BAT-26, an indicator of the replication error phenotype in colorectal cancers and cell lines. Cancer Res 1997; 57:300-303.
14. Togo G, Toda N, Kanai F, Kato N, Shiratori Y, Kishi K, Imazeki F, Makuuchi M, Omata M: A transforming growth factor β type II receptor gene mutation common in sporadic cecum cancer with microsatellite instability. Cancer Res 1996; 56:5620-5623.
15. Abdel-Rahman WM, Georgiades IB, Curtis LJ, Arends MJ, Wyllie AH: Role of BAX mutations in mismatch repair-deficient colorectal carcinogenesis. Oncogene 1999; 18:2139-2142.
16. Iacopetta BJ, Welch J, Soong R, House AK, Zhou X, Hamelin R: Mutation of the transforming growth factor-β type II receptor gene in right-sided colorectal cancer: relationship to clinicopothological features and genetic alterations. J Pathol 1998; 184:390-395.
17. Rampino N, Yamamoto H, Ionov Y, Li Y, Sawai H, Reed JC, Perucho M: Somatic frameshift mutations in the bax gene in colon cancers of the microsatellite mutator phenotype. Science 1997; 275:967-969.
18. Chang HJ, Kim SW, Kim YT, Kim WH: Loss of heterozygosity in dysplasia and carcinoma of the gallbladder. Modern Pathol 1999; 12:763-769.
19. Yoshida T, Sugai T, Habano W, Nakamura S, Uesugi N, Funato O, Saito K: Microsatellite instability in gallbladder carcinoma: two independent genetic pathways of gallbladder carcinogenesis. J Gastroenterol 2000; 35:768-774.
20. Saito K, Yeaton P, Sato J, Macdonald GA, Cherian SP, Boland CR: Genetic mechanisms of tumorigenesis in cholangiocarcinoma and gall bladder carcinoma. Hepatology 1995; 22:110. (Abstract)
21. Kim Yong-Tae, Kim J, Jang YH, Lee WJ, Ryu JK, Kim SW, Yoon YB, Kim CY: Genetic alterations in gallbladder adenoma, dysplasia and carcinoma. Cancer Lett 2001; 169:59-68.
22. Arzimanoglou II, Gilbert F, Barber HRK: Microsatellite instability in human solid tumors. Cancer 1998; 82:1808-1820.
23. Halling KC, Harper J, Moskaluk CA, Thibodeau SN, Petroni GR, Yustein AS, Tosi P, Minacci C, Roviello F, Piva P, Hamilton SR, Jackson CE, Powell SM: Origin of microsatellite instability in gastric cancer. Am J Pathol 1999; 155:205-211.
24. Dietmaier W, Wallinger S, Bocker T, Kullmann F, Fishel R, Ruschoff J: Diagnostic microsatellite instability: definition and correlation with mismatch repair protein expression. Cancer Res 1997; 57:4749-4756.
25. Thibodeau SN, French AJ, Cunningham JM, Tester D, Burgart LJ, Roche PC, McDonnell SK, Schaid DJ, Vockley CW, Michels VV, Farr GH Jr, O'Connell MJ: Microsatellite instability in colorectal cancer: different mutator phenotypes and the principle involvement of hMLH1. Cancer Res 1998; 58:1713-1718.