The insulin-like growth factor II receptor gene is mutated in genetically unstable cancers of the endometrium, stomach, and colorectum

Cancer Research

Volumn 57, Issue 10, 1997, Pages 1851-1854

  Ouyang, Hong ^a   Shiwaku, Hiromi O ^a   Hagiwara, Hisashi ^b   Miura, Ko ^a   Abe, Tadayoshi ^a   Kato, Yo ^c   Ohtani, Haruo ^a   Shiiba, Kenichi ^a   Souza, Rhonda F ^d   Meltzer, Stephen J ^d   Horii, Akira ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b HITACHI LTD   (Japan)

^c CANCER INSTITUTE   (Japan)

^d UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SOMATOMEDIN C RECEPTOR;

ARTICLE; COLON CARCINOGENESIS; COLORECTAL CANCER; DIGESTIVE SYSTEM CANCER; ENDOMETRIUM CANCER; FRAMESHIFT MUTATION; GENE MUTATION; GYNECOLOGIC CANCER; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; STOMACH CANCER;

BREAST NEOPLASMS; COLORECTAL NEOPLASMS; DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; ENDOMETRIAL NEOPLASMS; FEMALE; HISTONES; HUMANS; MUTATION; NEOPLASMS; OVARIAN NEOPLASMS; PANCREATIC NEOPLASMS; POLYMERASE CHAIN REACTION; RECEPTOR, IGF TYPE 2; REPETITIVE SEQUENCES, NUCLEIC ACID; STOMACH NEOPLASMS;

EID: 14444287748     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Dahms, N. M., Lobel, P., and Kornfeld, S. Mannose 6-phosphate receptors and lysosomal enzyme targeting. J. Biol. Chem., 264: 12115-12118, 1989.
2. Dennis, P. A., and Rifkin, D. B. Cellular activation of latent transforming growth factor β requires binding to the cation-independent mannose 6-phosphate/insulin-like growth factor type II receptor. Proc. Natl. Acad. Sci. USA, 88: 580-584, 1991.
3. Kornfeld, S. Structure and function of the mannose 6-phosphate/insulin-like growth factor II receptors. Annu. Rev. Biochem., 61: 307-330, 1992.
4. Laureys, G., Barton, D. E., Ullrich, A., and Francke, U. Chromosomal mapping of the gene for the type II insulin-like growth factor receptor/cation-independent mannose 6-phosphate receptor in man and mouse. Genomics, 3: 224-229, 1988.
5. Dutrillaux, B., Gerbault-Seureau, M., Zafrani, B. Characterization of chromosomal anomalies in human breast cancer. Cancer Genet. Cytogenet., 49: 203-217, 1990.
6. Lee, J. H., Kavanagh, J. J., Wildrick, D. M., Wharton, J. T., Blick, M. Frequent loss of heterozygosity on chromosomes 6q, 11, and 17 in human ovarian carcinomas. Cancer Res., 50: 2724-2728, 1990.
7. Devilee, P., van Vliet, M., van Sloun, P., Dijkshoorn, N. K., Hermans, J., Pearson, P. L., Cornelisse, C. J. Allelotype of human breast carcinoma: a second major site for loss of heterozygosity is on chromosome 6q. Oncogene, 6: 1705-1711, 1991.
8. Saito, S., Saito, H., Koi, S., Sagae, S., Kudo, R., Saito, J., Noda, K., Nakamura, Y. Fine-scale deletion mapping of the distal long arm of chromosome 6 in 70 human ovarian cancers. Cancer Res., 52: 5815-5817, 1992.
9. De Souza, A. T., Hankins, G. R., Washington, M. K., Fine, R. L., Orton, T. C., and Jirtle, R. L. Frequent loss of heterozygosity on 6q at the mannose 6-phosphate/insulin-like growth factor II receptor locus in human hepatocellular tumors. Oncogene, 10: 1725-1729, 1995.
10. Hahn, S. A., Seymour, A. B., Hoque, A. T., Schutte, M., da Costa, L. T., Redston, M. S., Caldas, C., Weinstein, C. L., Fischer, A., Yeo, C. J., Hruban, R. H., Kern, S. E. Allelotype of pancreatic adenocarcinoma using xenograft enrichment. Cancer Res., 55: 4670-4675, 1995.
11. Queimado, L., Seruca, R., Costa, P. A., and Castedo, S. Identification of two distinct regions of deletion at 6q in gastric carcinoma. Genes Chromosomes Cancer, 14: 28-34, 1995.
12. Honchel, R., McDonnell, S., Schaid, D. J., and Thibodeau, S. N. Tumor necrosis factor-α allelic frequency and chromosome 6 allelic imbalance in patients with colorectal cancer. Cancer Res., 56: 145-149, 1996.
13. Hankins, G. R., De Souza, A. T., Bentley, R. C., Patel, M. R., Marks, J. R., Iglehart, J. D., and Jirtle, R. L. M6P/IGF2 receptor: a candidate breast tumor suppressor gene. Oncogene, 12: 2003-2009, 1996.
14. Kimura, M., Abe, T., Sunamura, M., Matsuno, S., and Horii, A. Detailed deletion mapping on chromosome arm 12q in human pancreatic adenocarcinoma: identification of a 1-cM region of common allelic loss. Genes Chromosomes Cancer, 17: 88-93, 1996.
15. De Souza, A. T., Hankins, G. R., Washington, M. K., Orton, T. C., Jirtle, R. L. M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity. Nat. Genet., 11: 447-449, 1995.
16. Aaltonen, L. A., Peltomäki, P., Leach, F. S., Sistonen, P., Rylkkanen, L., Mecklin, J. P., Järvinen, H., Powell, S. M., Jen, J., Hamilton, S. R., Petersen, G. M., Kinzler, K. W., Vogelstein, B., and de la Chapelle, A. Clues to the pathogenesis of familial colorectal cancer. Science (Washington DC), 260: 812-816, 1993.
17. Thibodeau, S. N., Bren, G., Schaid, D. Microsatellite instability in cancer of the proximal colon. Science (Washington DC), 260: 816-819, 1993.
18. Ionov, Y., Peinado, M. A., Malkhosyan, S., Shibata, D., Perucho, M. Ubiquitous somatic mutation in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature (Lond.), 363: 558-561, 1993.
19. Han, H-J., Yanagisawa, A., Kato, Y., Park, J-G., Nakamura, Y. Genetic instability in pancreatic cancer and poorly differentiated type of gastric cancer. Cancer Res., 53: 5087-5089, 1993.
20. Markowitz, S., Wang, J., Myeroff, L., Parsons, R., Sun, L., Lutterbaugh, J., Fan, R. S., Zborowska, E., Kinzler, K. W., Vogelstein, B., Brattain, M., Willson, J. K. V. Inactivation of the Type II TGF-β receptor in colon cancer cells with microsatellite instability. Science (Washington DC), 268: 1336-1338, 1995.
21. Parsons, R., Myeroff, L. L., Liu, B., Willson, J. K. V., Markowitz, S. D., Kinzler, K., W., and Vogelstein, B. Microsatellite instability and mutations of the transforming growth factor β type II receptor gene in colorectal cancer. Cancer Res., 55: 5548-5550, 1995.
22. Meyeroff, L. L., Parsons. R., Kim, S-L., Hedrick, L., Cho, K. R., Orth, K., Mathis, M., Kinzler, K. W., Lutterbaugh, J., Park, K., Bang, Y-J., Lee, H. Y., Park, J-G., Lynch, H. T., Roberts, A. B., Vogelstein, B., and Markowitz, S. D. A transforming growth factor β receptor type II gene mutation common in colon and gastric but rare in endometrial cancers with microsatellite instability. Cancer Res., 55: 5545-5547, 1995.
23. Abe, T., Ouyang, H., Migita, T., Kato, Y., Kimura, M., Shiiba, K., Sunamura, M., Matsuno, S., and Horii, A. The somatic mutation frequency of the transforming growth factor β receptor type II gene varies widely among different cancers with microsatellite instability. Eur. J. Surg. Oncol., 22: 474-477, 1996.
24. Souza, R. F., Appel, R., Yin, J., Wang, S., Smolinski, K. N., Abraham, J. M., Zou, T-T., Shi, Y-Q., Lei, J., Cottrel, J., Cymes, K., Biden, K., Simms, L., Leggett, B., Lynch, P. M., Frazier, M., Powell, S. M., Harpaz, N., Sugimura, H., Young, J., and Meltzer, S. J. Microsatellite instability in the insulin-like growth factor II receptor gene in gastrointestinal tumours. Nat. Genet., 14: 255-257, 1996.
25. WHO. Histological Typing of Female Genital Tract Tumors, Ed. 2, pp. 13-18. Springer-Verlag, Heidelberg, Germany, 1994.
26. WHO. Histological Typing of Intestinal Tumors, Ed. 2, pp. 29-33. Springer-Verlag, Heidelberg, Germany, 1989.
27. Lauren, P. The two histological main types of gastric carcinoma, diffuse and so called intestinal type carcinoma. An attempt at a histo-clinical classification. Acta Pathol. Microbiol. Scand., 64: 31-49, 1965.
28. WHO. Histological Typing of Oesophageal and Gastric Tumors, Ed. 2, pp. 20-26. Springer-Verlag, Heidelberg, Germany, 1990.
29. International Federation of Gynecology and Obstetrics. FIGO Stages: 1988 Revision. Gynecol. Oncol., 35: 125-127, 1989.
30. Japanese Research Society for Gastric Cancer. The general rules for the gastric cancer study in surgery and pathology. Jpn. J. Surg., 11: 127-139, 1981.
31. Schutte, B. C., Ranade, K., Pruessner, J., and Dracopoli, N. Optimized conditions for cloning PCR products into an XcmI T-vector. Biotechniques, 22: 40-44, 1997.
32. Aaltonen, L. A., Peltomäki, P., Mecklin, J-P., Järvinen, H., Jass, J. R., Green, J. S., Lynch, H. T., Watson, P., Tallqvist, G., Luhola, M., Sistonen, P., Hamilton, S. R., Kinzler, K. W., Vogelstein, B., and de la Chapelle, A. Replication errors in benign and malignant tumors from hereditary nonpolyposis colorectal cancer patients. Cancer Res., 54: 1645-1648, 1994.
33. Strand, M., Prolla, T. A., Liskay, R. M., and Petes, T. D. Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair. Nature (Lond.), 365: 274-276, 1993.