The role of histological investigation in prognostic evaluation of advanced gastric cancer: Analysis of histological structure and molecular changes compared with invasive pattern and stage

Virchows Archiv

Volumn 439, Issue 2, 2001, Pages 158-169

  Chiaravalli, Anna ^b   Cornaggia, Matteo ^b   Furlan, Daniela ^b   Capella, Carlo ^a,b   Fiocca, Roberto ^c   Tagliabue, Giovanna ^d   Klersy, Catherine ^e   Solcia, Enrico ^f  

^a OSPEDALE DI CIRCOLO   (Italy)

^b UNIVERSITY OF INSUBRIA   (Italy)

^c UNIVERSITY OF GENOA   (Italy)

^d NATIONAL CANCER INSTITUTE   (Italy)

^e FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

^f UNIVERSITY OF PAVIA   (Italy)

Author keywords

Advanced gastric cancer; DUPAN 2; Epstein Barr virus; Histological classification; Microsatellite instability; Stage

Indexed keywords

DUPAN 2;

ADVANCED CANCER; ARTICLE; CANCER CLASSIFICATION; CANCER INVASION; CANCER STAGING; CANCER SURVIVAL; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MICROSATELLITE INSTABILITY; PRIORITY JOURNAL; PROGNOSIS; STATISTICAL ANALYSIS; STOMACH CANCER;

ADENOCARCINOMA; ANTIGENS, NEOPLASM; HERPESVIRUS 4, HUMAN; HUMANS; IMMUNOENZYME TECHNIQUES; IN SITU HYBRIDIZATION; MICROSATELLITE REPEATS; NEOPLASM INVASIVENESS; NEOPLASM STAGING; OLIGOSACCHARIDES; PROGNOSIS; REGRESSION ANALYSIS; RNA, VIRAL; STOMACH NEOPLASMS; SURVIVAL RATE; TUMOR MARKERS, BIOLOGICAL;

EID: 0034879583     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004280100441     Document Type: Article

References (64)

1. Long-term results of operation for carcinoma of the stomach in T1/T2 stages: Critical evaluation of the concept of early carcinoma of the stomach
2. Prognostic significance of the number of positive lymph nodes in gastric carcinoma
3. x expression in gastric carcinoma correlates with venous invasion and poor outcome
4. Prognostic factors in gastric cancer with serosal invasion - Univariate and multivariate analyses
5. E-cadherin gene mutations provide clues to diffuse type gastric carcinomas
6. Antigen processing for presentation by class 11 major histocompatibility complex requires cleavage by cathepsin E
7. Monoclonal antibodies against human pancreatic adenocarcinoma: Distribution of DU-PAN-2 antigen on glandular epithelia and adenocarcinomas
8. A multifactorial approach for the prognosis of patients with carcinoma of the stomach after curative resection
9. Indolent mucoid carcinoma of stomach
10. Microsatellite instability in intestinal- and diffuse-type gastric carcinoma
11. Lymphoepithelial carcinoma of the stomach with Epstein-Barr virus demonstrated by polymerase chain reaction
12. New elements for an updated classification of the carcinomas of the stomach
13. Immunohistochemical pattern of MSH2/MLH1 in familial and sporadic colorectal, gastric, endometrial and ovarian carcinomas with instability in microsatellite sequences
14. Microsatellite instability in the progression of gastric carcinoma
15. High prevalence of activated intraepithelial cytotoxic T lymphocytes and increased neoplastic cell apoptosis in colorectal carcinomas with microsatellite instability
16. Microsatellite instability at multiple loci in gastric carcinoma: Clinicopathologic implications and prognosis
17. A comparison of patterns of metastasis in gastric cancer by histologic type and age
18. Cathepsin E in follicle associated epithelium of intestine and tonsils: Localization to M cells and possible role in antigen processing
19. The foveolar cell component of gastric cancer
20. Incidence and prognostic significance of vascular invasion in 529 gastric-cancer patients
21. Tumor-cell dissociation at the invasion front: A new prognostic parameter in gastric cancer patients
22. Prognostic value of E-cadherin expression in 413 gastric carcinomas
23. Adenocarcinoma of the stomach with invasion limited to the muscolaris propria
24. x with MUC-1 apomucin in a pancreatic cancer cell line
25. Comparison of the prognostic significance between the number of metastatic lymph nodes and nodal stage based on their location with gastric cancer
26. Immunohistochemical expression of carbohydrate antigen 19-9 in gastric carcinoma
27. Epitope analysis of Span-1 and DUPAN-2 using synthetized glycoconjugates sialyllact-N-fucopentaose II and sialyllact-N-tetraose
28. Choriocarcinoma of the stomach: Pathogenesis and clinical characteristics
29. Histologic appearance of gastric carcinoma in high and low mortality countries: Comparison between Kyushu, Japan and Minnesota, USA
30. Molecular characterization of mucin-type antigen associated with human pancreatic cancer the DUPAN-2 antigen
31. The two histological main types of gastric carcinoma: Diffuse and so-called intestinal-type carcinoma. An attempt at a histoclinical classification
32. Genetic pattern, histological structure, and cellular phenotype in early and advanced gastric cancers: Evidence for structure-related genetic subsets and for loss of glandular structure during progression of some tumors
33. E-cadherin gene mutations provide a genetic basis for phenotypic divergence of mixed gastric carcinomas
34. The prognosis of gastric carcinoma as related to its morphologic characteristics
35. Goseki histological grading of gastric cancer is an important predictor of outcome
36. Small cell carcinoma of the stomach: A clinicopathological study of 17 cases
37. Poorly differentiated adenocarcinorna with lymphoid stroma (lymphoepithelioma-like carcinomas) of the stomach
38. Gastric carcinoma a pathological classification
39. Adenosquamous carcinoma of the stomach - A clinicopathologic analysis of 28 cases
40. Hepatoid adenocarcinoma of the stomach
41. a: A new functional prognostic factor in gastric cancer
42. Pathology and prognosis of gastric carcinoma. Findings in 10,000 patients who underwent primary gastrectomy
43. x can inhibit angiogenesis in vitro and in vivo
44. The clinicopathological features of gastric carcinomas with microsatellite instability may be mediated by mutations of different "Target Genes" - A study of the TGFβ RII, IGFII R, and BAX genes
45. Alpha-fetoprotein (AFP)-producing gastric carcinoma. Is it hepatoid differentiation?
46. Epstein-Barr virus detection by in situ hybridization in fine-needle aspiration biopsies
47. p53 gene mutations and protein nuclear accumulation are early events in intestinal type gastric cancer but late events in diffuse type
48. Prognostic significance of Lauren and Ming classifications and other pathologic parameters in gastric carcinoma
49. Prognosis in gastric carcinoma. The preeminence of staging and futility of histological classification
50. ECL cell tumor and poorly differentiated endocrine carcinoma of the stomach: Prognostic evaluation by pathological analysis
51. Ductal cancers of the pancreas frequently express markers of gastrointestinal epithelial cells
52. Intestinal and diffuse gastric cancers arise in a different background of Helicobacter pylori gastritis through different gene involvement
53. Gastric cancer - Morphological factors in five-year survival after gastrectomy
54. A survival study of intestinal and diffuse types of gastric carcinoma
55. Immunohistochemical studies on the main entrance-route of CA 19-9 into peripheral venous blood of gastric cancer patients
56. Extent of tumor vascularization correlates with prognosis and hematogenous metastasis in gastric carcinoma
57. p53 mutation in gastric cancer: A genetic model for carcinogenesis is common to gastric and colorectal cancer
58. Selectin ligands
59. Gastric carcinoma with lymphoid stroma. Its morphologic characteristics and prognostic correlations
60. Relation of number of positive lymph nodes to the prognosis of patients with primary gastric adenocarcinoma
61. Gastric cancers of the microsatellite mutator phenotype display characteristic genetic and clinical features
62. Determination of the replication error phenotype in human tumors without the requirement for matching normal DNA by analysis of mononucleotide repeat microsatellites