Tanshinone IIA inhibits human prostate cancer cells growth by induction of endoplasmic reticulum stress in vitro and in vivo

Prostate Cancer and Prostatic Diseases

Volumn 16, Issue 4, 2013, Pages 315-322

  Chiu, S C ^a   Huang, S Y ^b,c   Chen, S P ^d   Su, C C ^e   Chiu, T L ^d   Pang, C Y ^d,f  

^a Buddhist Compassion Relief Tzu Chi Foundation   (Taiwan)

^b MACKAY MEMORIAL HOSPITAL   (Taiwan)

^c JEN TEH JUNIOR COLLEGE OF MEDICINE   (Taiwan)

^d BUDDHIST TZU CHI GENERAL HOSPITAL   (Taiwan)

^e CHANGHUA CHRISTIAN HOSPITAL   (Taiwan)

^f TZU CHI UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; ER stress; GADD153 CHOP; LNCaP cells; Tanshinone IIA

Indexed keywords

APOPTOSIS RELATED PROTEIN; CARRIER PROTEIN; CCAAT ENHANCER BINDING PROTEIN; CELL CYCLE REGULATORY PROTEIN; CELL PROTEIN; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INOSITOL REQUIRING PROTEIN 1ALPHA; REGULATOR PROTEIN; SMALL INTERFERING RNA; TANSHINONE IIA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; DRUG STRUCTURE; ENDOPLASMIC RETICULUM STRESS; FLOW CYTOMETRY; GENE IDENTIFICATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATOR GENE; STRESS REGULATED GENE; TUMOR VOLUME; TUMOR XENOGRAFT; UPREGULATION;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; DITERPENES, ABIETANE; DRUGS, CHINESE HERBAL; ENDOPLASMIC RETICULUM STRESS; G1 PHASE CELL CYCLE CHECKPOINTS; HUMANS; MALE; MITOCHONDRIA; PROSTATIC NEOPLASMS; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84887617944     PISSN: 13657852     EISSN: 14765608     Source Type: Journal    
DOI: 10.1038/pcan.2013.38     Document Type: Article

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