-
1
-
-
32944463899
-
Angiogenesis
-
Folkman J. Angiogenesis. Annu Rev Med. 2006;57:1-18.
-
(2006)
Annu Rev Med
, vol.57
, pp. 1-18
-
-
Folkman, J.1
-
2
-
-
0000348061
-
Characterization of kringle domains of angiostatin as antagonists of endothelial cell migration, an important process in angiogenesis
-
Ji WR, Castellino FJ, Chang Y, et al. Characterization of kringle domains of angiostatin as antagonists of endothelial cell migration, an important process in angiogenesis. FASEB J. 1998;12:1731-1738.
-
(1998)
FASEB J
, vol.12
, pp. 1731-1738
-
-
Ji, W.R.1
Castellino, F.J.2
Chang, Y.3
-
3
-
-
0031454617
-
Endostatin: An endogenous inhibitor of angiogenesis and tumor growth
-
O'Reilly MS, Boehm T, Shing Y, et al. Endostatin: an endogenous inhibitor of angiogenesis and tumor growth. Cell. 1997;88:277-285.
-
(1997)
Cell
, vol.88
, pp. 277-285
-
-
O'Reilly, M.S.1
Boehm, T.2
Shing, Y.3
-
4
-
-
0037805549
-
Basement membranes: Structure, assembly and role in tumour angiogenesis
-
Kalluri R. Basement membranes: structure, assembly and role in tumour angiogenesis. Nat Rev Cancer. 2003;3:422-433.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 422-433
-
-
Kalluri, R.1
-
5
-
-
10544245024
-
Kringle domains of human angiostatin: Characterization of the antiproliferative activity on endothelial cells
-
Cao Y, Ji RW, Davidson D, et al. Kringle domains of human angiostatin: characterization of the antiproliferative activity on endothelial cells. J Biol Chem. 1996;271:29461-29467.
-
(1996)
J Biol Chem
, vol.271
, pp. 29461-29467
-
-
Cao, Y.1
Ji, R.W.2
Davidson, D.3
-
6
-
-
0033545930
-
Suppression of angiogenesis and tumor growth by the inhibitor K1-5 generated by plasmin-mediated proteolysis
-
Cao R, Wu HL, Veitonmaki N, et al. Suppression of angiogenesis and tumor growth by the inhibitor K1-5 generated by plasmin-mediated proteolysis. Proc Natl Acad Sci U S A. 1999;96:5728-5733.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 5728-5733
-
-
Cao, R.1
Wu, H.L.2
Veitonmaki, N.3
-
7
-
-
2442691834
-
Endothelial cell surface ATP synthase-triggered caspase-apoptotic pathway is essential for k1-5-induced antiangiogenesis
-
Veitonmaki N, Cao R, Wu LH, et al. Endothelial cell surface ATP synthase-triggered caspase-apoptotic pathway is essential for k1-5-induced antiangiogenesis. Cancer Res. 2004;64:3679-3686.
-
(2004)
Cancer Res
, vol.64
, pp. 3679-3686
-
-
Veitonmaki, N.1
Cao, R.2
Wu, L.H.3
-
8
-
-
0030930671
-
Kringle 5 of plasminogen is a novel inhibitor of endothelial cell growth
-
Cao Y, Chen A, An SS, Ji RW, Davidson D, Llinas M. Kringle 5 of plasminogen is a novel inhibitor of endothelial cell growth. J Biol Chem. 1997;272:22924-22928.
-
(1997)
J Biol Chem
, vol.272
, pp. 22924-22928
-
-
Cao, Y.1
Chen, A.2
An, S.S.3
Ji, R.W.4
Davidson, D.5
Llinas, M.6
-
9
-
-
0033583830
-
Kringle 5 causes cell cycle arrest and apoptosis of endothelial cells
-
Lu H, Dhanabal M, Volk R, et al. Kringle 5 causes cell cycle arrest and apoptosis of endothelial cells. Biochem Biophys Res Commun. 1999;258:668-673.
-
(1999)
Biochem Biophys Res Commun
, vol.258
, pp. 668-673
-
-
Lu, H.1
Dhanabal, M.2
Volk, R.3
-
10
-
-
0035423875
-
The glucose-regulated proteins: Stress induction and clinical applications
-
Lee AS. The glucose-regulated proteins: stress induction and clinical applications. Trends Biochem Sci. 2001;26:504-510.
-
(2001)
Trends Biochem Sci
, vol.26
, pp. 504-510
-
-
Lee, A.S.1
-
11
-
-
21144441659
-
Kringle 5 of human plasminogen induces apoptosis of endothelial and tumor cells through surface-expressed glucose-regulated protein 78
-
Davidson DJ, Haskell C, Majest S, et al. Kringle 5 of human plasminogen induces apoptosis of endothelial and tumor cells through surface-expressed glucose-regulated protein 78. Cancer Res. 2005;65:4663-4672.
-
(2005)
Cancer Res
, vol.65
, pp. 4663-4672
-
-
Davidson, D.J.1
Haskell, C.2
Majest, S.3
-
12
-
-
12944303650
-
Growth factor regulation of autophagy and cell survival in the absence of apoptosis
-
Lum JJ, Bauer DE, Kong M, et al. Growth factor regulation of autophagy and cell survival in the absence of apoptosis. Cell. 2005;120:237-248.
-
(2005)
Cell
, vol.120
, pp. 237-248
-
-
Lum, J.J.1
Bauer, D.E.2
Kong, M.3
-
13
-
-
2442482810
-
Autophagy as a cell death and tumor suppressor mechanism
-
Gozuacik D, Kimchi A. Autophagy as a cell death and tumor suppressor mechanism. Oncogene. 2004;23:2891-2906.
-
(2004)
Oncogene
, vol.23
, pp. 2891-2906
-
-
Gozuacik, D.1
Kimchi, A.2
-
14
-
-
0035032723
-
Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network
-
2:330-335
-
Kihara A, Kabeya Y, Ohsumi Y, Yoshimori T. Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network. EMBO Rep. 2001;2:330-335.
-
EMBO Rep. 2001
-
-
Kihara, A.1
Kabeya, Y.2
Ohsumi, Y.3
Yoshimori, T.4
-
15
-
-
0031026639
-
Characterization of p150, an adaptor protein for the human phosphatidylinositol (PtdIns) 3-kinase: Substrate presentation by phosphatidylinositol transfer protein to the p150.Ptdins 3-kinase complex
-
Panaretou C, Domin J, Cockcroft S, Waterfield MD. Characterization of p150, an adaptor protein for the human phosphatidylinositol (PtdIns) 3-kinase: substrate presentation by phosphatidylinositol transfer protein to the p150.Ptdins 3-kinase complex. J Biol Chem. 1997;272:2477-2485.
-
(1997)
J Biol Chem
, vol.272
, pp. 2477-2485
-
-
Panaretou, C.1
Domin, J.2
Cockcroft, S.3
Waterfield, M.D.4
-
16
-
-
0000906170
-
Induction of autophagy and inhibition of tumorigenesis by beclin 1
-
Liang XH, Jackson S, Seaman M, et al. Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature. 1999;402:672-676.
-
(1999)
Nature
, vol.402
, pp. 672-676
-
-
Liang, X.H.1
Jackson, S.2
Seaman, M.3
-
17
-
-
25144457455
-
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
-
Pattingre S, Tassa A, Qu X, et al. Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell. 2005;122:927-939.
-
(2005)
Cell
, vol.122
, pp. 927-939
-
-
Pattingre, S.1
Tassa, A.2
Qu, X.3
-
18
-
-
11844275275
-
Adeno-associated virus-mediated delivery of a mutant endostatin suppresses ovarian carcinoma growth in mice
-
Subramanian IV, Ghebre R, Ramakrishnan S. Adeno-associated virus-mediated delivery of a mutant endostatin suppresses ovarian carcinoma growth in mice. Gene Ther. 2005;12:30-38.
-
(2005)
Gene Ther
, vol.12
, pp. 30-38
-
-
Subramanian, I.V.1
Ghebre, R.2
Ramakrishnan, S.3
-
19
-
-
27944504351
-
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
-
Bjorkoy G, Lamark T, Brech A, et al. p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. J Cell Biol. 2005;171:603-614.
-
(2005)
J Cell Biol
, vol.171
, pp. 603-614
-
-
Bjorkoy, G.1
Lamark, T.2
Brech, A.3
-
20
-
-
33847026354
-
Autophagy delays apoptotic death in breast cancer cells following DNA damage
-
Abedin MJ, Wang D, McDonnell MA, Lehmann U, Kelekar A. Autophagy delays apoptotic death in breast cancer cells following DNA damage. Cell Death Differ. 2007;14:500-510.
-
(2007)
Cell Death Differ
, vol.14
, pp. 500-510
-
-
Abedin, M.J.1
Wang, D.2
McDonnell, M.A.3
Lehmann, U.4
Kelekar, A.5
-
21
-
-
0030844133
-
Tranilast inhibits the proliferation, chemotaxis and tube formation of human microvascular endothelial cells in vitro and angiogenesis in vivo
-
Isaji M, Miyata H, Ajisawa Y, Takehana Y, Yoshimura N. Tranilast inhibits the proliferation, chemotaxis and tube formation of human microvascular endothelial cells in vitro and angiogenesis in vivo. Br J Pharmacol. 1997;122:1061-1066.
-
(1997)
Br J Pharmacol
, vol.122
, pp. 1061-1066
-
-
Isaji, M.1
Miyata, H.2
Ajisawa, Y.3
Takehana, Y.4
Yoshimura, N.5
-
22
-
-
33646396500
-
Kringle 5 of human plasminogen suppresses hepatocellular carcinoma growth both in grafted and xenografted mice by anti-angiogenic activity
-
Yang X, Cheng R, Li C, et al. Kringle 5 of human plasminogen suppresses hepatocellular carcinoma growth both in grafted and xenografted mice by anti-angiogenic activity. Cancer Biol Ther. 2006;5:399-405.
-
(2006)
Cancer Biol Ther
, vol.5
, pp. 399-405
-
-
Yang, X.1
Cheng, R.2
Li, C.3
-
23
-
-
0141757272
-
Angiostatin antagonizes the action of VEGF-A in human endothelial cells via two distinct pathways
-
Chen YH, Wu HL, Chen CK, Huang YH, Yang BC, Wu LW. Angiostatin antagonizes the action of VEGF-A in human endothelial cells via two distinct pathways. Biochem Biophys Res Commun. 2003;310:804-810.
-
(2003)
Biochem Biophys Res Commun
, vol.310
, pp. 804-810
-
-
Chen, Y.H.1
Wu, H.L.2
Chen, C.K.3
Huang, Y.H.4
Yang, B.C.5
Wu, L.W.6
-
25
-
-
0030613796
-
Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria
-
Vander Heiden MG, Chandel NS, Williamson EK, Schumacker PT, Thompson CB. Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria. Cell. 1997;91:627-637.
-
(1997)
Cell
, vol.91
, pp. 627-637
-
-
Vander Heiden, M.G.1
Chandel, N.S.2
Williamson, E.K.3
Schumacker, P.T.4
Thompson, C.B.5
-
26
-
-
25144489068
-
Overview of cell death signaling pathways
-
Jin Z, El-Deiry WS. Overview of cell death signaling pathways. Cancer Biol Ther. 2005;4:139-163.
-
(2005)
Cancer Biol Ther
, vol.4
, pp. 139-163
-
-
Jin, Z.1
El-Deiry, W.S.2
-
27
-
-
33746166864
-
Disruption of autophagy at the maturation step by the carcinogen lindane is associated with the sustained mitogen-activated protein kinase/extracellular signalregulated kinase activity
-
Corcelle E, Nebout M, Bekri S, et al. Disruption of autophagy at the maturation step by the carcinogen lindane is associated with the sustained mitogen-activated protein kinase/extracellular signalregulated kinase activity. Cancer Res. 2006;66:6861-6870.
-
(2006)
Cancer Res
, vol.66
, pp. 6861-6870
-
-
Corcelle, E.1
Nebout, M.2
Bekri, S.3
-
28
-
-
0028836002
-
Monodansylcadaverine (MDC) is a specific in vivo marker for autophagic vacuoles
-
Biederbick A, Kern HF, Elsasser HP. Monodansylcadaverine (MDC) is a specific in vivo marker for autophagic vacuoles. Eur J Cell Biol. 1995;66:3-14.
-
(1995)
Eur J Cell Biol
, vol.66
, pp. 3-14
-
-
Biederbick, A.1
Kern, H.F.2
Elsasser, H.P.3
-
29
-
-
0034757896
-
A novel assay to study autophagy: Regulation of autophagosome vacuole size by amino acid deprivation
-
Munafo DB, Colombo MI. A novel assay to study autophagy: regulation of autophagosome vacuole size by amino acid deprivation. J Cell Sci. 2001;114:3619-3629.
-
(2001)
J Cell Sci
, vol.114
, pp. 3619-3629
-
-
Munafo, D.B.1
Colombo, M.I.2
-
30
-
-
0036778552
-
NCX-4016, a nitric oxide-releasing aspirin, protects endothelial cells against apoptosis by modulating mitochondrial function
-
Fiorucci S, Mencarelli A, Mannucci R, et al. NCX-4016, a nitric oxide-releasing aspirin, protects endothelial cells against apoptosis by modulating mitochondrial function. FASEB J. 2002;16:1645-1647.
-
(2002)
FASEB J
, vol.16
, pp. 1645-1647
-
-
Fiorucci, S.1
Mencarelli, A.2
Mannucci, R.3
-
31
-
-
33744988159
-
Autophagy: Is it cancer's friend or foe?
-
Marx J. Autophagy: is it cancer's friend or foe? Science. 2006;312:1160-1161.
-
(2006)
Science
, vol.312
, pp. 1160-1161
-
-
Marx, J.1
-
32
-
-
33749061748
-
Autophagy
-
Kelekar A. Autophagy. Ann N Y Acad Sci. 2006;1066:259-271.
-
(2006)
Ann N Y Acad Sci
, vol.1066
, pp. 259-271
-
-
Kelekar, A.1
-
33
-
-
0025694803
-
Both endocytic and endogenous protein degradation in fibroblasts is stimulated by serum/amino acid deprivation and inhibited by 3-methyladenine
-
Hendil KB, Lauridsen AM, Seglen PO. Both endocytic and endogenous protein degradation in fibroblasts is stimulated by serum/amino acid deprivation and inhibited by 3-methyladenine. Biochem J. 1990;272:577-581.
-
(1990)
Biochem J
, vol.272
, pp. 577-581
-
-
Hendil, K.B.1
Lauridsen, A.M.2
Seglen, P.O.3
-
34
-
-
0442323561
-
Autophagy: In sickness and in health
-
Cuervo AM. Autophagy: in sickness and in health. Trends Cell Biol. 2004;14:70-77.
-
(2004)
Trends Cell Biol
, vol.14
, pp. 70-77
-
-
Cuervo, A.M.1
-
35
-
-
0033578910
-
Antiangiogenic activity of the cleaved conformation of the serpin antithrombin
-
O'Reilly MS, Pirie-Shepherd S, Lane WS, Folkman J. Antiangiogenic activity of the cleaved conformation of the serpin antithrombin. Science. 1999;285:1926-1928.
-
(1999)
Science
, vol.285
, pp. 1926-1928
-
-
O'Reilly, M.S.1
Pirie-Shepherd, S.2
Lane, W.S.3
Folkman, J.4
-
36
-
-
0347626252
-
Autophagy: A regulated bulk degradation process inside cells
-
Yoshimori T. Autophagy: a regulated bulk degradation process inside cells. Biochem Biophys Res Commun. 2004;313:453-458.
-
(2004)
Biochem Biophys Res Commun
, vol.313
, pp. 453-458
-
-
Yoshimori, T.1
-
37
-
-
33745303045
-
Hypoxia signalling in cancer and approaches to enforce tumour regression
-
Pouyssegur J, Dayan F, Mazure NM. Hypoxia signalling in cancer and approaches to enforce tumour regression. Nature. 2006;441:437-443.
-
(2006)
Nature
, vol.441
, pp. 437-443
-
-
Pouyssegur, J.1
Dayan, F.2
Mazure, N.M.3
-
38
-
-
14044277429
-
The molecular machinery of autophagy: Unanswered questions
-
Klionsky DJ. The molecular machinery of autophagy: unanswered questions. J Cell Sci. 2005;118:7-18.
-
(2005)
J Cell Sci
, vol.118
, pp. 7-18
-
-
Klionsky, D.J.1
-
39
-
-
33645512801
-
Bcl-2 inhibition of autophagy: A new route to cancer?
-
Pattingre S, Levine B. Bcl-2 inhibition of autophagy: a new route to cancer? Cancer Res. 2006;66:2885-2888.
-
(2006)
Cancer Res
, vol.66
, pp. 2885-2888
-
-
Pattingre, S.1
Levine, B.2
-
40
-
-
0032932912
-
MAP kinases, phosphatidylinositol 3-kinase, and p70 S6 kinase mediate the mitogenic response of human endothelial cells to vascular endothelial growth factor
-
Yu Y, Sato JD. MAP kinases, phosphatidylinositol 3-kinase, and p70 S6 kinase mediate the mitogenic response of human endothelial cells to vascular endothelial growth factor. J Cell Physiol. 1999;178:235-246.
-
(1999)
J Cell Physiol
, vol.178
, pp. 235-246
-
-
Yu, Y.1
Sato, J.D.2
-
41
-
-
25144511910
-
The vascular endothelial growth factor (VEGF)/VEGF receptor system and its role under physiological and pathological conditions
-
Takahashi H, Shibuya M. The vascular endothelial growth factor (VEGF)/VEGF receptor system and its role under physiological and pathological conditions. Clin Sci (Lond). 2005;109:227-241.
-
(2005)
Clin Sci (Lond)
, vol.109
, pp. 227-241
-
-
Takahashi, H.1
Shibuya, M.2
-
42
-
-
0038711442
-
The voltage-dependent anion channel is a receptor for plasminogen kringle 5 on human endothelial cells
-
Gonzalez-Gronow M, Kalfa T, Johnson CE, Gawdi G, Pizzo SV. The voltage-dependent anion channel is a receptor for plasminogen kringle 5 on human endothelial cells. J Biol Chem. 2003;278:27312-27318.
-
(2003)
J Biol Chem
, vol.278
, pp. 27312-27318
-
-
Gonzalez-Gronow, M.1
Kalfa, T.2
Johnson, C.E.3
Gawdi, G.4
Pizzo, S.V.5
-
43
-
-
33749460895
-
-
Ermakova SP, Kang BS, Choi BY, et al. (-)-epigallocatechin gallate overcomes resistance to Etoposide-induced cell death by targeting the molecular chaperone glucose-regulated protein 78. Cancer Res. 2006;66:9260-9269.
-
Ermakova SP, Kang BS, Choi BY, et al. (-)-epigallocatechin gallate overcomes resistance to Etoposide-induced cell death by targeting the molecular chaperone glucose-regulated protein 78. Cancer Res. 2006;66:9260-9269.
-
-
-
-
44
-
-
0031036872
-
Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
-
Yang J, Liu X, Bhalla K, et al. Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science. 1997;275:1129-1132.
-
(1997)
Science
, vol.275
, pp. 1129-1132
-
-
Yang, J.1
Liu, X.2
Bhalla, K.3
-
45
-
-
0031037897
-
The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
-
Kluck RM, Bossy-Wetzel E, Green DR, Newmeyer DD. The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science. 1997;275:1132-1136.
-
(1997)
Science
, vol.275
, pp. 1132-1136
-
-
Kluck, R.M.1
Bossy-Wetzel, E.2
Green, D.R.3
Newmeyer, D.D.4
-
46
-
-
0035266313
-
Up-Regulation of Bcl-2 in microvascular endothelial cells enhances intratumoral angiogenesis and accelerates tumor growth
-
Nor JE, Christensen J, Liu J, et al. Up-Regulation of Bcl-2 in microvascular endothelial cells enhances intratumoral angiogenesis and accelerates tumor growth. Cancer Res. 2001;61:2183-2188.
-
(2001)
Cancer Res
, vol.61
, pp. 2183-2188
-
-
Nor, J.E.1
Christensen, J.2
Liu, J.3
-
47
-
-
0033635733
-
BH3-Only proteins-essential initiators of apoptotic cell death
-
Huang DC, Strasser A. BH3-Only proteins-essential initiators of apoptotic cell death. Cell. 2000;103:839-842.
-
(2000)
Cell
, vol.103
, pp. 839-842
-
-
Huang, D.C.1
Strasser, A.2
-
48
-
-
0033179760
-
BCL-2 family members and the mitochondria in apoptosis
-
Gross A, McDonnell JM, Korsmeyer SJ. BCL-2 family members and the mitochondria in apoptosis. Genes Dev. 1999;13:1899-1911.
-
(1999)
Genes Dev
, vol.13
, pp. 1899-1911
-
-
Gross, A.1
McDonnell, J.M.2
Korsmeyer, S.J.3
-
49
-
-
0035870257
-
Beclin 1 contains a leucine-rich nuclear export signal that is required for its autophagy and tumor suppressor function
-
Liang XH, Yu J, Brown K, Levine B. Beclin 1 contains a leucine-rich nuclear export signal that is required for its autophagy and tumor suppressor function. Cancer Res. 2001;61:3443-3449.
-
(2001)
Cancer Res
, vol.61
, pp. 3443-3449
-
-
Liang, X.H.1
Yu, J.2
Brown, K.3
Levine, B.4
|