-
1
-
-
36849043044
-
Ginsenosides: Are any of them candidates for drugs acting on the central nervous system?
-
DOI 10.1111/j.1527-3458.2007.00023.x
-
Nah SY, Kim DH, Rhim H. Ginsenosides: are any of them candidates for drugs acting on the central nervous system? CNS Drug Rev 2007; 13: 381-404. (Pubitemid 350233470)
-
(2007)
CNS Drug Reviews
, vol.13
, Issue.4
, pp. 381-404
-
-
Nah, S.-Y.1
Kim, D.-H.2
Rhim, H.3
-
2
-
-
41149123051
-
+ channel current inhibitions
-
DOI 10.1248/bpb.31.480
-
+ channel current inhibitions. Biol Pharm Bull 2008; 31: 480-6. (Pubitemid 351442150)
-
(2008)
Biological and Pharmaceutical Bulletin
, vol.31
, Issue.3
, pp. 480-486
-
-
Lee, J.-H.1
Choi, S.-H.2
Lee, B.-H.3
Yoon, I.-S.4
Shin, T.-J.5
Pyo, M.K.6
Lee, S.-M.7
Rhim, H.8
Park, M.H.9
Park, T.Y.10
Nah, S.-Y.11
-
4
-
-
33847359267
-
3A receptors
-
DOI 10.1016/j.neuropharm.2006.12.001, PII S0028390806004102
-
3A receptors. Neuropharmacology 2007; 52: 1139-50. (Pubitemid 46335709)
-
(2007)
Neuropharmacology
, vol.52
, Issue.4
, pp. 1139-1150
-
-
Lee, B.-H.1
Lee, J.-H.2
Lee, S.-M.3
Jeong, S.M.4
Yoon, I.-S.5
Lee, J.-H.6
Choi, S.-H.7
Pyo, M.K.8
Rhim, H.9
Kim, H.-C.10
Jang, C.-G.11
Lee, B.-C.12
Park, C.-S.13
Nah, S.-Y.14
-
5
-
-
11144285485
-
3H]flunitrazepam binding in rat brain by the prolonged ventricular infusion of transformed ginsenosides
-
DOI 10.1007/s11064-004-7034-2
-
3H]muscimol and [3H]flunitrazepam binding in rat brain by the prolonged ventricular infusion of transformed ginsenosides. Neurochem Res 2004; 29: 2257-66. (Pubitemid 40036898)
-
(2004)
Neurochemical Research
, vol.29
, Issue.12
, pp. 2257-2266
-
-
Jang, S.1
Ryu, J.H.2
Kim, D.-H.3
Oh, S.4
-
6
-
-
4544338752
-
3 antagonizes NMDA receptors through a glycine modulatory site in rat cultured hippocampal neurons
-
DOI 10.1016/j.bbrc.2004.08.106, PII S0006291X04018777
-
3 antagonizes NMDA receptors through a glycine modulatory site in rat cultured hippocampal neurons. Biochem Biophys Res Commun 2004; 323: 416-24. (Pubitemid 39221114)
-
(2004)
Biochemical and Biophysical Research Communications
, vol.323
, Issue.2
, pp. 416-424
-
-
Kim, S.1
Kim, T.2
Ahn, K.3
Park, W.-K.4
Nah, S.-Y.5
Rhim, H.6
-
8
-
-
84863461647
-
Gintonin, newly identified compounds from ginseng, is novel lysophosphatidic acids-protein complexes and activates G protein-coupled lysophosphatidic acid receptors with high affinity
-
Hwang SH, Shin TJ, Choi SH, Cho HJ, Lee BH, Pyo MK, et al. Gintonin, newly identified compounds from ginseng, is novel lysophosphatidic acids-protein complexes and activates G protein-coupled lysophosphatidic acid receptors with high affinity. Mol Cells 2012; 33: 151-62.
-
(2012)
Mol Cells
, vol.33
, pp. 151-162
-
-
Hwang, S.H.1
Shin, T.J.2
Choi, S.H.3
Cho, H.J.4
Lee, B.H.5
Pyo, M.K.6
-
9
-
-
84868576848
-
Lysophospholipids and their receptors in the central nervous system
-
Choi JW, Chun J. Lysophospholipids and their receptors in the central nervous system. Biochim Biophys Acta 2013; 1831: 20-32.
-
(2013)
Biochim Biophys Acta
, vol.1831
, pp. 20-32
-
-
Choi, J.W.1
Chun, J.2
-
10
-
-
33846882015
-
3 against homocysteine-induced excitotoxicity in rat hippocampus
-
DOI 10.1016/j.brainres.2006.12.047, PII S0006899306035591
-
Kim JH, Cho SY, Lee JH, Jeong SM, Yoon IS, Lee BH, et al. Neuropro-tective effects of ginsenoside Rg3 against homocysteine-induced excitotoxicity in rat hippocampus. Brain Res 2007; 1136: 190-9. (Pubitemid 46217786)
-
(2007)
Brain Research
, vol.1136
, Issue.1
, pp. 190-199
-
-
Kim, J.-H.1
Cho, S.Y.2
Lee, J.-H.3
Jeong, S.M.4
Yoon, I.-S.5
Lee, B.-H.6
Lee, J.-H.7
Pyo, M.K.8
Lee, S.-M.9
Chung, J.-M.10
Kim, S.11
Rhim, H.12
Oh, J.-W.13
Nah, S.-Y.14
-
11
-
-
85027953473
-
Gintonin, a ginseng-derived novel ingredient, evokes long-term potentiation through N-methyl-D-aspartic acid receptor activation: Involvement of LPA receptors
-
Shin TJ, Kim HJ, Kwon BJ, Choi SH, Kim HB, Hwang SH, et al. Gintonin, a ginseng-derived novel ingredient, evokes long-term potentiation through N-methyl-D-aspartic acid receptor activation: Involvement of LPA receptors. Mol Cells 2012; 34: 563-72.
-
(2012)
Mol Cells
, vol.34
, pp. 563-572
-
-
Shin, T.J.1
Kim, H.J.2
Kwon, B.J.3
Choi, S.H.4
Kim, H.B.5
Hwang, S.H.6
-
12
-
-
51349106992
-
Botanical characteristics, pharmacological effects and medicinal components of Korean Panax ginseng C A Meyer
-
Choi KT. Botanical characteristics, pharmacological effects and medicinal components of Korean Panax ginseng C A Meyer. Acta Pharmacol Sin 2008; 29: 1109-18.
-
(2008)
Acta Pharmacol Sin
, vol.29
, pp. 1109-1118
-
-
Choi, K.T.1
-
13
-
-
84865039191
-
Ginsenosides as anticancer agents: In vitro and in vivo activities, structure-activity relationships, and molecular mechanisms of action
-
Nag SA, Qin JJ, Wang W, Wang MH, Wang H, Zhang R. Ginsenosides as anticancer agents: in vitro and in vivo activities, structure-activity relationships, and molecular mechanisms of action. Front Pharmacol 2012; 3: 25.
-
(2012)
Front Pharmacol
, vol.3
, pp. 25
-
-
Nag, S.A.1
Qin, J.J.2
Wang, W.3
Wang, M.H.4
Wang, H.5
Zhang, R.6
-
19
-
-
21344437013
-
Evidence that the tertiary structure of 20(S)-ginsenoside Rg(3) with tight hydrophobic packing near the chiral center is important for Na+ channel regulation
-
Kang DI, Lee JY, Yang JY, Jeong SM, Lee JH, Nah SY, et al. Evidence that the tertiary structure of 20(S)-ginsenoside Rg(3) with tight hydrophobic packing near the chiral center is important for Na+ channel regulation. Biochem Biophys Res Commun 2005; 333: 1194-201.
-
(2005)
Biochem Biophys Res Commun
, vol.333
, pp. 1194-1201
-
-
Kang, D.I.1
Lee, J.Y.2
Yang, J.Y.3
Jeong, S.M.4
Lee, J.H.5
Nah, S.Y.6
-
20
-
-
66649093210
-
A role for Leu247 residue within transmembrane domain 2 in ginsenoside-mediated alpha7 nicotinic acetylcholine receptor regulation
-
Lee BH, Choi SH, Pyo MK, Shin TJ, Hwang SH, Kim BR, et al. A role for Leu247 residue within transmembrane domain 2 in ginsenoside-mediated alpha7 nicotinic acetylcholine receptor regulation. Mol Cells 2009; 27: 591-9.
-
(2009)
Mol Cells
, vol.27
, pp. 591-599
-
-
Lee, B.H.1
Choi, S.H.2
Pyo, M.K.3
Shin, T.J.4
Hwang, S.H.5
Kim, B.R.6
-
21
-
-
18744412989
-
Modulating effect of ginseng saponins on heterologously expressed HERG currents in Xenopus oocytes
-
Kim CS, Son SJ, Kim HS, Kim YD, Lee KS, Jeon BH, et al. Modulating effect of ginseng saponins on heterologously expressed HERG currents in Xenopus oocytes. Acta Pharmacol Sin 2005; 26: 551-8.
-
(2005)
Acta Pharmacol Sin
, vol.26
, pp. 551-558
-
-
Kim, C.S.1
Son, S.J.2
Kim, H.S.3
Kim, Y.D.4
Lee, K.S.5
Jeon, B.H.6
-
22
-
-
0041308173
-
A receptor channels expressed in Xenopus oocytes
-
Choi SE, Choi S, Lee JH, Whiting PJ, Lee SM, Nah SY. Effects of ginsenosides on GABAA receptor channels expressed in Xenopus oocytes. Arch Pharm Res 2003; 26: 28-33. (Pubitemid 44698783)
-
(2003)
Archives of Pharmacal Research
, vol.26
, Issue.1
, pp. 28-33
-
-
Choi, S.-E.1
Choi, S.2
Lee, J.-H.3
Whiting, P.J.4
Lee, S.-M.5
Nah, S.-Y.6
-
23
-
-
0037840607
-
Effects of ginsenosides on glycine receptor α1 channels expressed in Xenopus oocytes
-
Noh JH, Choi S, Lee JH, Betz H, Kim JI, Park CS, et al. Effects of ginsenosides on glycine receptor alpha1 channels expressed in Xenopus oocytes. Mol Cells 2003; 15: 34-9. (Pubitemid 41582939)
-
(2003)
Molecules and Cells
, vol.15
, Issue.1
, pp. 34-39
-
-
Noh, J.-H.1
Choi, S.2
Lee, J.-H.3
Betz, H.4
Kim, J.-I.5
Park, C.-S.6
Lee, S.-M.7
Nah, S.-Y.8
-
25
-
-
0034531895
-
Effects of Panax notoginseng saponins on vascular endothelial cells in vitro
-
Kwan CY, Kwan TK. Effects of Panax notoginseng saponins on vascular endothelial cells in vitro. Acta Pharmacol Sin 2000; 21: 1101-5. (Pubitemid 32012717)
-
(2000)
Acta Pharmacologica Sinica
, vol.21
, Issue.12
, pp. 1101-1105
-
-
Kwan, C.-Y.1
Kwan, T.K.2
-
28
-
-
2042506662
-
+ currents of the rabbit coronary artery smooth muscle cells
-
+ currents of the rabbit coronary artery smooth muscle cells. J Ginseng Res 1999; 23: 230-4.
-
(1999)
J Ginseng Res
, vol.23
, pp. 230-234
-
-
Chung, I.1
Kim, N.D.2
-
29
-
-
36849059687
-
+ channel activity in the smooth muscle of the rabbit coronary artery
-
+ channel activity in the smooth muscle of the rabbit coronary artery. J Ginseng Res 1999; 23: 235-8.
-
(1999)
J Ginseng Res
, vol.23
, pp. 235-238
-
-
Chung, I.1
Lee, J.S.2
-
30
-
-
0034529038
-
Effect of Korean red ginseng on blood pressure and nitric oxide production
-
Jeon BH, Kim CS, Kim HS, Park JB, Nam KY, Chang SJ. Effect of Korean red ginseng on blood pressure and nitric oxide production. Acta Pharmacol Sin 2000; 21: 1095-100. (Pubitemid 32012716)
-
(2000)
Acta Pharmacologica Sinica
, vol.21
, Issue.12
, pp. 1095-1100
-
-
Jeon, B.H.1
Kim, C.S.2
Kim, H.-S.3
Park, J.-B.4
Nam, K.Y.5
Chang, S.-J.6
-
31
-
-
84862782050
-
Cardioprotective effects of saponins from Panax japonicus on acute myocardial ischemia against oxidative stress-triggered damage and cardiac cell death in rats
-
He H, Xu J, Xu Y, Zhang C, Wang H, He Y, et al. Cardioprotective effects of saponins from Panax japonicus on acute myocardial ischemia against oxidative stress-triggered damage and cardiac cell death in rats. J Ethnopharmacol 2012; 140: 73-82.
-
(2012)
J Ethnopharmacol
, vol.140
, pp. 73-82
-
-
He, H.1
Xu, J.2
Xu, Y.3
Zhang, C.4
Wang, H.5
He, Y.6
-
32
-
-
84862797972
-
The saponin of red ginseng protects the cardiac myocytes against ischemic injury in vitro and in vivo
-
Li HX, Han SY, Ma X, Zhang K, Wang L, Ma ZZ, et al. The saponin of red ginseng protects the cardiac myocytes against ischemic injury in vitro and in vivo. Phytomedicine 2012; 19: 477-83.
-
(2012)
Phytomedicine
, vol.19
, pp. 477-483
-
-
Li, H.X.1
Han, S.Y.2
Ma, X.3
Zhang, K.4
Wang, L.5
Ma, Z.Z.6
-
33
-
-
3042820953
-
2+ current by ginsenoside Re, an ingredient of Panax ginseng, in guinea-pig cardiomyocytes
-
DOI 10.1038/sj.bjp.0705814
-
2+ current by ginsenoside Re, an ingredient of Panax ginseng, in guinea-pig cardiomyocytes. Br J Pharmacol 2004; 142: 567-75. (Pubitemid 38869871)
-
(2004)
British Journal of Pharmacology
, vol.142
, Issue.3
, pp. 567-575
-
-
Bai, C.-X.1
Takahashi, C.2
Masumiya, H.3
Sawanobori, T.4
Furukawa, T.5
-
34
-
-
33751119582
-
Ginsenoside Re, a main phytosterol of Panax ginseng, activates cardiac potassium channels via a nongenomic pathway of sex hormones
-
DOI 10.1124/mol.106.028134
-
Furukawa T, Bai CX, Kaihara A, Ozaki E, Kawano T, Nakaya Y, et al. Ginsenoside Re, a main phytosterol of Panax ginseng, activates cardiac potassium channels via a nongenomic pathway of sex hormones. Mol Pharmacol 2006; 70: 1916-24. (Pubitemid 44771907)
-
(2006)
Molecular Pharmacology
, vol.70
, Issue.6
, pp. 1916-1924
-
-
Furukawa, T.1
Bai, C.-X.2
Kaihara, A.3
Ozaki, E.4
Kawano, T.5
Nakaya, Y.6
Awais, M.7
Sato, M.8
Umezawa, Y.9
Kurokawa, J.10
-
35
-
-
0344549853
-
Ginseng pharmacology: Multiple constituents and multiple actions
-
DOI 10.1016/S0006-2952(99)00212-9, PII S0006295299002129
-
Attele AS, Wu JA, Yuan CS. Ginseng pharmacology: multiple constituents and multiple actions. Biochem Pharmacol 1999; 58: 1685-93. (Pubitemid 29505408)
-
(1999)
Biochemical Pharmacology
, vol.58
, Issue.11
, pp. 1685-1693
-
-
Attele, A.S.1
Wu, J.A.2
Yuan, C.-S.3
-
36
-
-
69049099988
-
Anxiolytic-like effects of ginsenosides Rg3 and Rh2 from red ginseng in the elevated plus-maze model
-
Kim TW, Choi HJ, Kim NJ, Kim DH. Anxiolytic-like effects of ginsenosides Rg3 and Rh2 from red ginseng in the elevated plus-maze model. Planta Med 2009; 75: 836-9.
-
(2009)
Planta Med
, vol.75
, pp. 836-839
-
-
Kim, T.W.1
Choi, H.J.2
Kim, N.J.3
Kim, D.H.4
-
37
-
-
24944562026
-
Effects of Korean red ginseng extract on cisplatin-induced nausea and vomiting
-
Kim JH, Yoon IS, Lee BH, Choi SH, Lee JH, Jeong SM, et al. Effects of Korean red ginseng extract on cisplatin-induced nausea and vomiting. Arch Pharm Res 2005; 28: 680-4.
-
(2005)
Arch Pharm Res
, vol.28
, pp. 680-684
-
-
Kim, J.H.1
Yoon, I.S.2
Lee, B.H.3
Choi, S.H.4
Lee, J.H.5
Jeong, S.M.6
-
39
-
-
12144290636
-
- current by microinjection of inositol hexakisphosphate in Xenopus laevis oocytes: Involvement of GRK2 and β-arrestin I
-
DOI 10.1074/jbc.M310824200
-
2+-activated Cl-current by microinjection of inositol hexakisphosphate in Xenopus laevis oocytes: involvement of GRK2 and beta-arrestin I. J Biol Chem 2004; 279: 9912-21. (Pubitemid 38372591)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.11
, pp. 9912-9921
-
-
Lee, J.-H.1
Jeong, S.M.2
Lee, B.-H.3
Noh, H.-S.4
Kim, B.-K.5
Kim, J.-I.6
Rhim, H.7
Kim, H.-C.8
Kim, K.-M.9
Nah, S.-Y.10
-
40
-
-
79959905574
-
Novel glycoproteins from ginseng
-
Pyo MK, Shin TJ, Choi SH, Lee BH, Pyo MK, Lee JH, et al. Novel glycoproteins from ginseng. J Ginseng Res 2011; 35: 92-103.
-
(2011)
J Ginseng Res
, vol.35
, pp. 92-103
-
-
Pyo, M.K.1
Shin, T.J.2
Choi, S.H.3
Lee, B.H.4
Pyo, M.K.5
Lee, J.H.6
-
41
-
-
84863942661
-
Gintonin, a ginseng-derived lysophosphatidic acid receptor ligand, attenuates Alzheimer's disease-related neuropathies: Involvement of non-amyloidogenic processing
-
Hwang SH, Shin EJ, Shin TJ, Lee BH, Choi SH, Kang J, et al. Gintonin, a ginseng-derived lysophosphatidic acid receptor ligand, attenuates Alzheimer's disease-related neuropathies: involvement of non-amyloidogenic processing. J Alzheimers Dis 2012; 31: 207-23.
-
(2012)
J Alzheimers Dis
, vol.31
, pp. 207-223
-
-
Hwang, S.H.1
Shin, E.J.2
Shin, T.J.3
Lee, B.H.4
Choi, S.H.5
Kang, J.6
-
42
-
-
0026795116
-
Lysophosphatidates bound to serum albumin activate membrane currents in Xenopus oocytes and neurite retraction in PC12 pheochromocytoma cells
-
Tigyi G, Miledi R. Lysophosphatidates bound to serum albumin activate membrane currents in Xenopus oocytes and neurite retraction in PC12 pheochromocytoma cells. J Biol Chem 1992; 267: 21360-7.
-
(1992)
J Biol Chem
, vol.267
, pp. 21360-21367
-
-
Tigyi, G.1
Miledi, R.2
-
44
-
-
83855160838
-
Autotaxin and LPA receptor signaling in cancer
-
Houben AJ, Moolenaar WH. Autotaxin and LPA receptor signaling in cancer. Cancer Metastasis Rev 2011; 30: 557-65.
-
(2011)
Cancer Metastasis Rev
, vol.30
, pp. 557-565
-
-
Houben, A.J.1
Moolenaar, W.H.2
-
45
-
-
84873673939
-
Suppression of metastasis of intravenously-inoculated B16/F10 melanoma cells by the novel ginseng-derived ingredient, gintonin: Involvement of autotaxin inhibition
-
Hwang SH, Lee BH, Kim HJ, Cho HJ, Shin HC, Im KS, et al. Suppression of metastasis of intravenously-inoculated B16/F10 melanoma cells by the novel ginseng-derived ingredient, gintonin: Involvement of autotaxin inhibition. Int J Oncol 2013; 42: 317-26.
-
(2013)
Int J Oncol
, vol.42
, pp. 317-326
-
-
Hwang, S.H.1
Lee, B.H.2
Kim, H.J.3
Cho, H.J.4
Shin, H.C.5
Im, K.S.6
-
46
-
-
0037131366
-
Identification of human plasma lysophospholipase D, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase
-
DOI 10.1074/jbc.M205623200
-
Tokumura A, Majima E, Kariya Y, Tominaga K, Kogure K, Yasuda K, et al. Identification of human plasma lysophospholipase D, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phos-phodiesterase. J Biol Chem 2002; 277: 39436-42. (Pubitemid 35190918)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.42
, pp. 39436-39442
-
-
Tokumura, A.1
Majima, E.2
Kariya, Y.3
Tominaga, K.4
Kogure, K.5
Yasuda, K.6
Fukuzawa, K.7
-
47
-
-
1542359873
-
Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production
-
Umezu-Goto M, Kishi Y, Taira A, Hama K, Dohmae N, Takio K, et al. Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production. J Cell Biol 2002; 158: 227-33.
-
(2002)
J Cell Biol
, vol.158
, pp. 227-233
-
-
Umezu-Goto, M.1
Kishi, Y.2
Taira, A.3
Hama, K.4
Dohmae, N.5
Takio, K.6
|