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Volumn 21, Issue 1, 2006, Pages 52-62

Effects of ginsenosides and their metabolites on voltage-dependent Ca2+ channel subtypes

Author keywords

1C , 1B , 1A , 1E , and 1G type Ca2+ channels; Ginseng; Ginsenosides; Xenopus oocytes

Indexed keywords

BARIUM; CALCIUM CHANNEL; GINSENOSIDE; GINSENOSIDE M 4; GINSENOSIDE RB 1; GINSENOSIDE RC; GINSENOSIDE RE; GINSENOSIDE RG 1; GINSENOSIDE RG 3; GINSENOSIDE RH 2; PROTOPANAXADIOL; SAPONIN DERIVATIVE; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL;

EID: 33645747465     PISSN: 10168478     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (48)

References (42)
  • 1
    • 0032531818 scopus 로고    scopus 로고
    • Calcium - A life and death signal
    • Berridge, M. J., Bootman, M. D., and Lipp, P. (1998) Calcium - a life and death signal. Nature 395, 645-668.
    • (1998) Nature , vol.395 , pp. 645-668
    • Berridge, M.J.1    Bootman, M.D.2    Lipp, P.3
  • 2
    • 9044238837 scopus 로고    scopus 로고
    • Determinants of the G protein-dependent opioid modulation of neuronal calcium channels
    • Bourinet, E., Soong, T. W., Stea, A., and Snutch, T. P. (1996) Determinants of the G protein-dependent opioid modulation of neuronal calcium channels. Proc. Natl. Acad. Sci. USA 93, 1486-1491.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 1486-1491
    • Bourinet, E.1    Soong, T.W.2    Stea, A.3    Snutch, T.P.4
  • 3
    • 0024093449 scopus 로고
    • Glutamate neurotoxicity and diseases of the nervous system
    • Choi, D. W. (1988) Glutamate neurotoxicity and diseases of the nervous system. Neuron 1, 623-634.
    • (1988) Neuron , vol.1 , pp. 623-634
    • Choi, D.W.1
  • 5
    • 0037012734 scopus 로고    scopus 로고
    • Effects of ginsenosides, active components of ginseng, on nicotinic acetylcholine receptors expressed in Xenopus oocytes
    • Choi, S., Jung, S. Y., Lee, J. H., Sala, F., Criado, M., et al. (2002a) Effects of ginsenosides, active components of ginseng, on nicotinic acetylcholine receptors expressed in Xenopus oocytes. Eur. J. Pharmacol. 442, 34-45.
    • (2002) Eur. J. Pharmacol. , vol.442 , pp. 34-45
    • Choi, S.1    Jung, S.Y.2    Lee, J.H.3    Sala, F.4    Criado, M.5
  • 6
    • 0036208475 scopus 로고    scopus 로고
    • Functional expression of a novel ginsenoside Rf binding protein from rat brain mRNA in Xenopus oocytes
    • Choi, S., Jung, S. Y., Ko, Y. S., Koh, S. R., Rhim, H., et al. (2002b) Functional expression of a novel ginsenoside Rf binding protein from rat brain mRNA in Xenopus oocytes. Mol. Pharmacol. 61, 928-935.
    • (2002) Mol. Pharmacol. , vol.61 , pp. 928-935
    • Choi, S.1    Jung, S.Y.2    Ko, Y.S.3    Koh, S.R.4    Rhim, H.5
  • 8
    • 0023505641 scopus 로고
    • The use of Xenopus oocytes for the study of ion channels
    • Dascal, N. (1987) The use of Xenopus oocytes for the study of ion channels. CRC Crit. Rev. Biochem. 22, 317-387.
    • (1987) CRC Crit. Rev. Biochem. , vol.22 , pp. 317-387
    • Dascal, N.1
  • 9
    • 0030764219 scopus 로고    scopus 로고
    • Riluzole protects from motor deficits and striatal degeneration produced by systemic 3-nitropropionic acid intoxication in rats
    • Guyot, M. C., Palfi, S., Stutzmann, J. M., Maziere, M., Hantraye, P., et al. (1997) Riluzole protects from motor deficits and striatal degeneration produced by systemic 3-nitropropionic acid intoxication in rats. Neuroscience 81, 141-149.
    • (1997) Neuroscience , vol.81 , pp. 141-149
    • Guyot, M.C.1    Palfi, S.2    Stutzmann, J.M.3    Maziere, M.4    Hantraye, P.5
  • 10
    • 0036633130 scopus 로고    scopus 로고
    • Prevention of growth and metastasis of murine malenoma through enhanced natural-killer cytotoxicity by fatty acid-conjugate of protopanaxatriol
    • Hasegawa, H., Suzuki, R., Nagaoka, T., Tezuka, Y., Kadota, S., et al. (2002) Prevention of growth and metastasis of murine malenoma through enhanced natural-killer cytotoxicity by fatty acid-conjugate of protopanaxatriol. Biol. Pharm. Bull. 25, 861-866.
    • (2002) Biol. Pharm. Bull. , vol.25 , pp. 861-866
    • Hasegawa, H.1    Suzuki, R.2    Nagaoka, T.3    Tezuka, Y.4    Kadota, S.5
  • 11
    • 33646057761 scopus 로고    scopus 로고
    • Ginseng and ion channels: Are ginsenosides, active components ot Panax ginseng, differential modulator of ion channels
    • Jeong, S. M. and Nah, S. Y. (2005) Ginseng and ion channels: are ginsenosides, active components ot Panax ginseng, differential modulator of ion channels. J. Ginseng Res. 29, 19-26.
    • (2005) J. Ginseng Res. , vol.29 , pp. 19-26
    • Jeong, S.M.1    Nah, S.Y.2
  • 13
    • 0031597590 scopus 로고    scopus 로고
    • 2+ channels and membrane capacitance in rat adrenal chromaffin cells
    • 2+ channels and membrane capacitance in rat adrenal chromaffin cells. Brain Res. Bull. 46, 245-251.
    • (1998) Brain Res. Bull. , vol.46 , pp. 245-251
    • Kim, H.S.1    Lee, J.H.2    Koo, Y.S.3    Nah, S.Y.4
  • 17
    • 20144389219 scopus 로고    scopus 로고
    • Protective effects of ginseng saponins on 3-nitropropionic acid-induced striatal degeneration in rats
    • Kim, J. H., Kim, S., Yoon, I. S., Lee, J. H., Jang, B. J., et al. (2005b) Protective effects of ginseng saponins on 3-nitropropionic acid-induced striatal degeneration in rats. Neuropharmacology 48, 743-756.
    • (2005) Neuropharmacology , vol.48 , pp. 743-756
    • Kim, J.H.1    Kim, S.2    Yoon, I.S.3    Lee, J.H.4    Jang, B.J.5
  • 18
    • 0036386954 scopus 로고    scopus 로고
    • Inhibitory effect of ginsenosides on NMDA receptor-mediated signals in rat hippocampal neurons
    • Kim, S., Ahn, K., Oh, T. H., Nah, S. Y., and Rhim, H. (2002) Inhibitory effect of ginsenosides on NMDA receptor-mediated signals in rat hippocampal neurons. Biochem. Biophys. Res. Commun. 296, 247-254.
    • (2002) Biochem. Biophys. Res. Commun. , vol.296 , pp. 247-254
    • Kim, S.1    Ahn, K.2    Oh, T.H.3    Nah, S.Y.4    Rhim, H.5
  • 19
    • 0032509752 scopus 로고    scopus 로고
    • Properties of ginseng saponin inhibition of catecholamine secretion in bovine adrenal chromaffin cells
    • Kudo, K., Tachikawa, E., Kashimoto, T., and Takahashi, E. (1998) Properties of ginseng saponin inhibition of catecholamine secretion in bovine adrenal chromaffin cells. Eur. J. Pharmacol. 341, 139-144.
    • (1998) Eur. J. Pharmacol. , vol.341 , pp. 139-144
    • Kudo, K.1    Tachikawa, E.2    Kashimoto, T.3    Takahashi, E.4
  • 20
    • 0033560010 scopus 로고    scopus 로고
    • Cloning and expression of a novel member of the low voltage-activated T-type calcium channel family
    • Lee, J. H., Daud, A. N., Cribbs, L. L., Lacerda, A. E., Perevrzev, A., et al. (1999) Cloning and expression of a novel member of the low voltage-activated T-type calcium channel family. J. Neurosci. 19, 1912-1921.
    • (1999) J. Neurosci. , vol.19 , pp. 1912-1921
    • Lee, J.H.1    Daud, A.N.2    Cribbs, L.L.3    Lacerda, A.E.4    Perevrzev, A.5
  • 21
    • 0037036187 scopus 로고    scopus 로고
    • Protective effect of ginsenosides, active ingredients of Panax ginseng, on kainate-induced neurotoxicity in rat hippocampus
    • Lee, J. H., Kim, S. H., Kim D, Hong, H. N., and Nah, S. Y. (2001) Protective effect of ginsenosides, active ingredients of Panax ginseng, on kainate-induced neurotoxicity in rat hippocampus. Neurosci. Lett. 325, 129-133.
    • (2001) Neurosci. Lett. , vol.325 , pp. 129-133
    • Lee, J.H.1    Kim, S.H.2    Kim, D.3    Hong, H.N.4    Nah, S.Y.5
  • 26
    • 0025775195 scopus 로고
    • Primary structure and functional expression from complementary DNA of a brain calcium channel
    • Mori, Y., Friedrich, T., Kim, M. S., Mikami, A., Nakai, J., et al. (1991) Primary structure and functional expression from complementary DNA of a brain calcium channel. Nature 350, 398-402.
    • (1991) Nature , vol.350 , pp. 398-402
    • Mori, Y.1    Friedrich, T.2    Kim, M.S.3    Mikami, A.4    Nakai, J.5
  • 27
    • 4644350854 scopus 로고    scopus 로고
    • Antinociceptive effect of different types of calcium channel inhibitors and the distribution of various calcium channel alpha 1 subunits in the dorsal horn of spinal cord in mice
    • Murakami, M., Nakagawasai, O., Suzuki, T., Mobarakeh, I., Sakurada, Y., et al. (2004) Antinociceptive effect of different types of calcium channel inhibitors and the distribution of various calcium channel alpha 1 subunits in the dorsal horn of spinal cord in mice. Brain Res. 1024, 122-129.
    • (2004) Brain Res. , vol.1024 , pp. 122-129
    • Murakami, M.1    Nakagawasai, O.2    Suzuki, T.3    Mobarakeh, I.4    Sakurada, Y.5
  • 28
    • 0002721949 scopus 로고    scopus 로고
    • Ginseng, recent advances and trend
    • Nah, S. Y. (1997) Ginseng, recent advances and trend. Korea J. Ginseng Sci. 21, 1-12.
    • (1997) Korea J. Ginseng Sci. , vol.21 , pp. 1-12
    • Nah, S.Y.1
  • 29
    • 0028343966 scopus 로고
    • Ginseng root extract inhibits calcium channels in rat sensory neurons through a similar path, but different receptor, as μ-type opioids
    • Nah, S. Y. and McCleskey, E. W. (1994) Ginseng root extract inhibits calcium channels in rat sensory neurons through a similar path, but different receptor, as μ-type opioids. J. Ethnopharmacol. 42, 45-51.
    • (1994) J. Ethnopharmacol. , vol.42 , pp. 45-51
    • Nah, S.Y.1    McCleskey, E.W.2
  • 31
    • 0030582095 scopus 로고    scopus 로고
    • 2+ channel identity of CA3-CA1 neurotransmission in rat hippocampal slices
    • 2+ channel identity of CA3-CA1 neurotransmission in rat hippocampal slices. Eur. J. Pharmacol. 306, 41-50.
    • (1996) Eur. J. Pharmacol. , vol.306 , pp. 41-50
    • Nooney, J.1    Lodge, D.2
  • 32
    • 0028179146 scopus 로고
    • Calcium channel beta-subunit binds to a conserved motif in the I-II cytoplasmic linker of the alpha 1-subunit
    • Pragnell, M., De Waard, M., Mori, Y., Tanabe, T., Snutch, T. P., et al. (1994) Calcium channel beta-subunit binds to a conserved motif in the I-II cytoplasmic linker of the alpha 1-subunit. Nature 368, 67-70.
    • (1994) Nature , vol.368 , pp. 67-70
    • Pragnell, M.1    De Waard, M.2    Mori, Y.3    Tanabe, T.4    Snutch, T.P.5
  • 37
    • 0027454312 scopus 로고
    • Different types of calcium channels mediate central synaptic transmission
    • Takahashi, T. and Momiyama, A. (1993) Different types of calcium channels mediate central synaptic transmission. Nature 366, 156-158.
    • (1993) Nature , vol.366 , pp. 156-158
    • Takahashi, T.1    Momiyama, A.2
  • 38
    • 0031303557 scopus 로고    scopus 로고
    • In vivo antimetastatic action of ginseng protopanaxadiol saponins is based on their intestinal bacterial metabolites after oral administration
    • Wakabayashi, C., Hasegawa, H., Murata, J., and Saiki, I. (1997) In vivo antimetastatic action of ginseng protopanaxadiol saponins is based on their intestinal bacterial metabolites after oral administration. Oncol. Res. 9, 411-417.
    • (1997) Oncol. Res. , vol.9 , pp. 411-417
    • Wakabayashi, C.1    Hasegawa, H.2    Murata, J.3    Saiki, I.4
  • 39
    • 0032577217 scopus 로고    scopus 로고
    • An intestinal bacterial metabolite of ginseng protopanaxadiol saponins has the ability to induce apoptosis in tumor cells
    • Wakabayashi, C., Murakami, K., Hasegawa, H., Murata, J., and Saiki, I. (1998) An intestinal bacterial metabolite of ginseng protopanaxadiol saponins has the ability to induce apoptosis in tumor cells. Biochem. Biophys. Res. Commun. 249, 725-730.
    • (1998) Biochem. Biophys. Res. Commun. , vol.249 , pp. 725-730
    • Wakabayashi, C.1    Murakami, K.2    Hasegawa, H.3    Murata, J.4    Saiki, I.5
  • 40
    • 0033232710 scopus 로고    scopus 로고
    • 2+ current in neurohypophysial terminals preferentially regulates oxytocin secretion
    • 2+ current in neurohypophysial terminals preferentially regulates oxytocin secretion. J. Neurosci. 19, 9235-9241.
    • (1999) J. Neurosci. , vol.19 , pp. 9235-9241
    • Wang, G.1    Dayanithi, G.2    Newcomb, R.3    Lemos, J.R.4
  • 41
    • 2042480027 scopus 로고    scopus 로고
    • 2+-dependent gonadotropin-releasing hormone release in GT1-7 cells
    • 2+-dependent gonadotropin-releasing hormone release in GT1-7 cells. Endocrinology 45, 2375-2383.
    • (2004) Endocrinology , vol.45 , pp. 2375-2383
    • Watanabe, M.1    Sakuma, Y.2    Kato, M.3
  • 42
    • 0028258190 scopus 로고
    • 2+ channels in supporting hippocampal synaptic transmission
    • 2+ channels in supporting hippocampal synaptic transmission. Science 264, 107-111.
    • (1994) Science , vol.264 , pp. 107-111
    • Wheeler, D.B.1    Randall, A.2    Tsien, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.