Ginsenoside Rg 3 antagonizes NMDA receptors through a glycine modulatory site in rat cultured hippocampal neurons

Biochemical and Biophysical Research Communications

Volumn 323, Issue 2, 2004, Pages 416-424

  Kim, Sunoh ^a,b   Kim, Taehyun ^a   Ahn, Kwangseog ^b   Park, Woo Kyu ^c   Nah, Seung Yeol ^d   Rhim, Hyewhon ^a  

^a Korea Institute of Science and Technology   (South Korea)

^b Korea University   (South Korea)

^c Korea Research Institute of Chemical Technology   (South Korea)

^d University of Seoul   (South Korea)

Author keywords

Fura 2 AM; Ginseng; Ginsenoside Rg 3; Glycine; Hippocampal neurons; Intracellular Ca 2+; MTT assay; Neurotoxicity; NMDA

Indexed keywords

DIZOCILPINE; GINSENOSIDE RG 3; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; SAPONIN; UNCLASSIFIED DRUG; GINSENOSIDE; N METHYLASPARTIC ACID; NEUROPROTECTIVE AGENT;

ANIMAL CELL; ARTICLE; CELL CULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; HIPPOCAMPUS; INHIBITION KINETICS; NONHUMAN; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; STATISTICAL SIGNIFICANCE; ANIMAL; APOPTOSIS; CALCIUM SIGNALING; CELL MEMBRANE POTENTIAL; CYTOLOGY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; NERVE CELL; PHYSIOLOGY; PRENATAL DEVELOPMENT; SPRAGUE DAWLEY RAT;

PANAX GINSENG;

ANIMALS; APOPTOSIS; CALCIUM SIGNALING; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; GINSENOSIDES; HIPPOCAMPUS; MEMBRANE POTENTIALS; N-METHYLASPARTATE; NEURONS; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 4544338752     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.08.106     Document Type: Article

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