Identification of ginsenoside interaction sites in 5-HT3A receptors

Neuropharmacology

Volumn 52, Issue 4, 2007, Pages 1139-1150

  Lee, Byung Hwan ^a   Lee, Jun Ho ^a   Lee, Sang Mok ^a   Jeong, Sang Min ^a   Yoon, In Soo ^a   Lee, Joon Hee ^a   Choi, Sun Hye ^a   Pyo, Mi Kyung ^a   Rhim, Hyewhon ^b   Kim, Hyoung Chun ^c   Jang, Choon Gon ^d   Lee, Byoung Cheol ^e   Park, Chul Seung ^e   Nah, Seung Yeol ^a  

^a Konkuk University   (South Korea)

^b Korea Institute of Science and Technology   (South Korea)

^c Korea Institute of Drug Abuse   (South Korea)

^d Sungkyunkwan University   (South Korea)

^e Gwangju Institute of Science and Technology (GIST)   (South Korea)

Author keywords

5 HT3A receptor; Ginsenosides; Site directed mutagenesis; Xenopus oocytes

Indexed keywords

3,4,5 TRIMETHOXYBENZOIC ACID 8 (DIETHYLAMINO)OCTYL ESTER; DILTIAZEM; GINSENG EXTRACT; GINSENOSIDE RG 3; MUTANT PROTEIN; SEROTONIN 3 RECEPTOR; SEROTONIN 3A RECEPTOR; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; DOSE RESPONSE; DRUG BINDING SITE; DRUG PROTEIN BINDING; DRUG RECEPTOR BINDING; FEMALE; GINSENG; IC 50; ION CURRENT; MICROELECTRODE; NEUROPHARMACOLOGY; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN DOMAIN; SITE DIRECTED MUTAGENESIS; VOLTAGE CLAMP; WILD TYPE; XENOPUS LAEVIS;

ANIMALS; CALCIUM CHANNEL BLOCKERS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; GALLIC ACID; GINSENOSIDES; MEMBRANE POTENTIALS; MODELS, MOLECULAR; MUTATION; OOCYTES; PATCH-CLAMP TECHNIQUES; RECEPTORS, SEROTONIN, 5-HT3; SEROTONIN; XENOPUS LAEVIS;

EID: 33847359267     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2006.12.001     Document Type: Article

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