Gintonin, newly identified compounds from ginseng, is novel lysophosphatidic acids-protein complexes and activates G protein-coupled lysophosphatidic acid receptors with high affinity

Molecules and Cells

Volumn 33, Issue 2, 2012, Pages 151-162

  Hwang, Sung Hee ^a   Shin, Tae Joon ^a   Choi, Sun Hye ^a   Cho, Hee Jung ^a   Lee, Byung Hwan ^a   Pyo, Mi Kyung ^b   Lee, Jun Ho ^a   Kang, Jiyeon ^a   Kim, Hyeon Joong ^a   Park, Chan Woo ^a   Shin, Ho Chul ^a   Nah, Seung Yeol ^a  

^a Konkuk University   (South Korea)

^b International Ginseng Herb Research Institute   (South Korea)

Author keywords

Ginseng; Gintonin; LPA receptors; LPA protein complexes

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; GINSENG EXTRACT; GINTONIN; LYSOPHOSPHATIDIC ACID RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PERTUSSIS TOXIN; PHOSPHOLIPASE C; RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL MIGRATION; CELL PROLIFERATION; CELL STRAIN; CELL STRUCTURE; CONTROLLED STUDY; GENE EXPRESSION; GENETIC TRANSCRIPTION; GINSENG; LIQUID CHROMATOGRAPHY; NEUROBLASTOMA CELL; NONHUMAN; OOCYTE; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEOMICS; RAT; RECEPTOR AFFINITY; RECEPTOR BINDING; SIGNAL TRANSDUCTION; TANDEM MASS SPECTROMETRY; UMBILICAL VEIN ENDOTHELIAL CELL; XENOPUS LAEVIS;

ANIMALS; CALCIUM SIGNALING; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; ENDOTHELIUM, VASCULAR; GENE EXPRESSION PROFILING; GLYCOPROTEINS; GTP-BINDING PROTEINS; HUMANS; ISOXAZOLES; LYSOPHOSPHOLIPIDS; MOLECULAR TARGETED THERAPY; MUTAGENESIS, SITE-DIRECTED; MUTATION; PANAX; PC12 CELLS; PERTUSSIS TOXIN; PLANT PROTEINS; PROPIONIC ACIDS; PROTEIN BINDING; RATS; RECEPTORS, LYSOPHOSPHATIDIC ACID; TRANSGENES;

PANAX GINSENG; RATTUS;

EID: 84863461647     PISSN: 10168478     EISSN: 02191032     Source Type: Journal    
DOI: 10.1007/s10059-012-2216-z     Document Type: Article

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