Cardioprotective effects of saponins from Panax japonicus on acute myocardial ischemia against oxidative stress-triggered damage and cardiac cell death in rats

Journal of Ethnopharmacology

Volumn 140, Issue 1, 2012, Pages 73-82

  He, Haibo ^a   Xu, Jia ^a   Xu, Yuanqing ^a   Zhang, Changcheng ^a   Wang, Hongwu ^a   He, Yumin ^a   Wang, Ting ^a   Yuan, Ding ^a  

^a CHINA THREE GORGES UNIVERSITY   (China)

Author keywords

Cardiac cell death; Myocardial ischemia; Oxidative stress; Reactive oxygen species; Saponins from Panax japonicus

Indexed keywords

CASPASE 3; CATALASE; CHIKUSETSUSAPONIN 4; CHIKUSETSUSAPONIN 4A; CHIKUSETSUSAPONIN 5; COPPER ZINC SUPEROXIDE DISMUTASE; CREATINE KINASE; EXTRACELLULAR SUPEROXIDE DISMUTASE; GLUTATHIONE PEROXIDASE; LACTATE DEHYDROGENASE; MALONALDEHYDE; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; PANAX JAPONICUS SAPONIN; PANAX JAPONICUS SAPONIN 2; PANAXSAPONIN RE; PROTEIN BAX; PROTEIN BCL 2; SAPONIN; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; XANTHINE OXIDASE;

ACUTE HEART INFARCTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL STRUCTURE; CONTROLLED STUDY; DOWN REGULATION; DRUG STRUCTURE; GENE EXPRESSION; GENE SEQUENCE; HEART FUNCTION; HEART HEMODYNAMICS; HEART INFARCTION SIZE; HEART MUSCLE CELL; HEART PROTECTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOPATHOLOGY; LEFT ANTERIOR DESCENDING CORONARY ARTERY; LIGHT SCATTERING; MALE; NONHUMAN; OXIDATIVE STRESS; PANAX; PANAX JAPONICUS; RAT; REAL TIME POLYMERASE CHAIN REACTION;

ANIMALS; ANTIOXIDANTS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CELL DEATH; CREATINE KINASE; HEART; L-LACTATE DEHYDROGENASE; MALE; MALONDIALDEHYDE; MYOCARDIAL INFARCTION; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; OXIDATIVE STRESS; PANAX; PHYTOTHERAPY; PLANT EXTRACTS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; SAPONINS; SUPEROXIDE DISMUTASE; XANTHINES;

PANAX JAPONICUS; RATTUS;

EID: 84862782050     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2011.12.024     Document Type: Article

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