메뉴 건너뛰기




Volumn 26, Issue 5, 2005, Pages 551-558

Modulating effect of ginseng saponins on heterologously expressed HERG currents in Xenopus oocytes

Author keywords

Action potentials; Ginseng saponins; Patch clamp techniques; Potassium channels; Xenopus laevis

Indexed keywords

GINSENG EXTRACT; GINSENG SAPONIN; GINSENOSIDE; INWARDLY RECTIFYING POTASSIUM CHANNEL; PANAXIDIOL; PANAXITRIOL; POTASSIUM CHANNEL HERG; SAPONIN; UNCLASSIFIED DRUG;

EID: 18744412989     PISSN: 16714083     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1745-7254.2005.00116.x     Document Type: Article
Times cited : (9)

References (32)
  • 1
    • 0029853361 scopus 로고    scopus 로고
    • Cardiovascular protection by ginsenosides and their nitric oxide releasing action
    • Chen X. Cardiovascular protection by ginsenosides and their nitric oxide releasing action. Clin Exp Pharmacol Physiol 1996; 23: 728-32.
    • (1996) Clin Exp Pharmacol Physiol , vol.23 , pp. 728-732
    • Chen, X.1
  • 2
    • 0032790389 scopus 로고    scopus 로고
    • Beneficial effects of ginsenosides of stems and leaves on cardiac and coronary vascular functions after 12-hour rat heart preservation
    • Zhang JM, Matsuura Y, Sueda T, Orihashi K. Beneficial effects of ginsenosides of stems and leaves on cardiac and coronary vascular functions after 12-hour rat heart preservation. Transplant Proc 1999; 31: 2175-8.
    • (1999) Transplant Proc , vol.31 , pp. 2175-2178
    • Zhang, J.M.1    Matsuura, Y.2    Sueda, T.3    Orihashi, K.4
  • 4
    • 0028528353 scopus 로고
    • Protective effects of ginsenoside on myocardiac ischemic and reperfusion injuries
    • Zhan Y, Xu XH, Jiang YP. Protective effects of ginsenoside on myocardiac ischemic and reperfusion injuries. J Natl Med J China 1994; 74: 626-8.
    • (1994) J Natl Med J China , vol.74 , pp. 626-628
    • Zhan, Y.1    Xu, X.H.2    Jiang, Y.P.3
  • 5
    • 0023751593 scopus 로고
    • Negative chronotropic and inotropic effects of Panax notoginseng saponins
    • Wu JX, Chen JX. Negative chronotropic and inotropic effects of Panax notoginseng saponins. Acta Pharmacol Sin 1988; 9: 409-12.
    • (1988) Acta Pharmacol Sin , vol.9 , pp. 409-412
    • Wu, J.X.1    Chen, J.X.2
  • 6
    • 0023972814 scopus 로고
    • Studies on anti-arrhythmia effects of panaxatriol saponins isolated from Panax notoginseng
    • Li XJ, Zhang BH. Studies on anti-arrhythmia effects of panaxatriol saponins isolated from Panax notoginseng. Acta Pharm Sin 1988; 23: 168-73.
    • (1988) Acta Pharm Sin , vol.23 , pp. 168-173
    • Li, X.J.1    Zhang, B.H.2
  • 7
    • 0020358031 scopus 로고
    • Cardiac arrhythmia induced by hypothalamic stimulation in cardiac ischemic rabbits and the antiarrhythmic action of Panax ginseng
    • Zhang RB, Li ZY, Shi HY. Cardiac arrhythmia induced by hypothalamic stimulation in cardiac ischemic rabbits and the antiarrhythmic action of Panax ginseng. Acta Pharmacol Sin 1982; 3: 226-30.
    • (1982) Acta Pharmacol Sin , vol.3 , pp. 226-230
    • Zhang, R.B.1    Li, Z.Y.2    Shi, H.Y.3
  • 8
    • 0027409152 scopus 로고
    • + channels and control of ventricular repolarization in the heart
    • + channels and control of ventricular repolarization in the heart. Fundam Clin Pharmacol 1993; 7: 19-28
    • (1993) Fundam Clin Pharmacol , vol.7 , pp. 19-28
    • Carmeliet, E.1
  • 9
    • 0025351245 scopus 로고
    • + current. Differential sensitivity to block by class III antiarrhythmic agents
    • + current. Differential sensitivity to block by class III antiarrhythmic agents. J Gen Physiol 1990; 96: 195-215.
    • (1990) J Gen Physiol , vol.96 , pp. 195-215
    • Sanguinetti, M.C.1    Jurkiewicz, N.K.2
  • 12
    • 0030819954 scopus 로고    scopus 로고
    • A quantitative analysis of the activation and inactivation kinetics of HERG ex pressed in Xenopus oocytes
    • Wang S, Liu S, Morales MJ, Strauss HC, Rasmusson RL. A quantitative analysis of the activation and inactivation kinetics of HERG ex pressed in Xenopus oocytes. J Physiol 1997; 502: 45-60.
    • (1997) J Physiol , vol.502 , pp. 45-60
    • Wang, S.1    Liu, S.2    Morales, M.J.3    Strauss, H.C.4    Rasmusson, R.L.5
  • 15
    • 0029994611 scopus 로고    scopus 로고
    • Blockade of HERG channels expressed in Xenopus oocytes by the histamine receptor antagonists terfenadine and astemizole
    • Suessbrich H, Waldegger S, Lang F, Busch AE. Blockade of HERG channels expressed in Xenopus oocytes by the histamine receptor antagonists terfenadine and astemizole. FEBS Lett 1996; 385: 77-80.
    • (1996) FEBS Lett , vol.385 , pp. 77-80
    • Suessbrich, H.1    Waldegger, S.2    Lang, F.3    Busch, A.E.4
  • 16
    • 0030704669 scopus 로고    scopus 로고
    • A mechanism for the proarrhythmic effects of cisapride (Propulsid): High affinity blockade of the human cardiac potassium channel HERG
    • Rampe D, Roy ML, Dennis A, Brown AM. A mechanism for the proarrhythmic effects of cisapride (Propulsid): high affinity blockade of the human cardiac potassium channel HERG. FEBS Lett 1997; 417: 28-32.
    • (1997) FEBS Lett , vol.417 , pp. 28-32
    • Rampe, D.1    Roy, M.L.2    Dennis, A.3    Brown, A.M.4
  • 17
    • 0033052403 scopus 로고    scopus 로고
    • Thioridazine lengthens repolarization of cardiac ventricular myocytes by blocking the delayed rectifier potassium current
    • Drolet B, Vincent F, Rail J, Chahine M, Deschenes D, Nadeau S, et al. Thioridazine lengthens repolarization of cardiac ventricular myocytes by blocking the delayed rectifier potassium current. J Pharmacol Exp Ther 1999; 288: 1261-8.
    • (1999) J Pharmacol Exp Ther , vol.288 , pp. 1261-1268
    • Drolet, B.1    Vincent, F.2    Rail, J.3    Chahine, M.4    Deschenes, D.5    Nadeau, S.6
  • 18
    • 0036089685 scopus 로고    scopus 로고
    • Blockade of human cardiac potassium channel human ether-a-go-go-related gene (HERG) by macrolide antibiotics
    • Volberg WA, Koci BJ, Su W, Lin J, Zhou J. Blockade of human cardiac potassium channel human ether-a-go-go-related gene (HERG) by macrolide antibiotics. J Pharmacol Exp Ther 2002; 302: 320-7.
    • (2002) J Pharmacol Exp Ther , vol.302 , pp. 320-327
    • Volberg, W.A.1    Koci, B.J.2    Su, W.3    Lin, J.4    Zhou, J.5
  • 20
    • 0034975654 scopus 로고    scopus 로고
    • Kr: The hERG channel
    • Kr: the hERG channel. J Mol Cell Cardiol 2001; 33: 835-49.
    • (2001) J Mol Cell Cardiol , vol.33 , pp. 835-849
    • Tseng, G.N.1
  • 21
    • 0142169482 scopus 로고    scopus 로고
    • Electrophysiological effects of ginseng and ginsenoside Re in guinea pig ventricular myocytes
    • Bai CX, Sunami A, Namiki T, Sawanobori T, Furukawa T. Electrophysiological effects of ginseng and ginsenoside Re in guinea pig ventricular myocytes. Eur J Pharmacol 2003; 476: 35-44.
    • (2003) Eur J Pharmacol , vol.476 , pp. 35-44
    • Bai, C.X.1    Sunami, A.2    Namiki, T.3    Sawanobori, T.4    Furukawa, T.5
  • 26
    • 0032970148 scopus 로고    scopus 로고
    • Dysfunction of delayed rectifier potassium channels in an inherited cardiac arrhythmia
    • Sanguinetti MC. Dysfunction of delayed rectifier potassium channels in an inherited cardiac arrhythmia. Ann N Y Acad Sci 1999; 868: 406-13.
    • (1999) Ann N Y Acad Sci , vol.868 , pp. 406-413
    • Sanguinetti, M.C.1
  • 27
    • 0032516934 scopus 로고    scopus 로고
    • HERG channel dysfunction in human long QT syndrome. Intracellular transport and functional defects
    • Zhou Z, Gong Q, Epstein ML, January CT. HERG channel dysfunction in human long QT syndrome. Intracellular transport and functional defects. J Biol Chem 1998; 273: 21061-6.
    • (1998) J Biol Chem , vol.273 , pp. 21061-21066
    • Zhou, Z.1    Gong, Q.2    Epstein, M.L.3    January, C.T.4
  • 28
    • 0035824896 scopus 로고    scopus 로고
    • + channel activity is regulated by changes in phosphatidyl inositol 4,5-bisphosphate
    • + channel activity is regulated by changes in phosphatidyl inositol 4,5-bisphosphate. Circ Res 2001; 89: 1168-76.
    • (2001) Circ Res , vol.89 , pp. 1168-1176
    • Bian, J.1    Cui, J.2    McDonald, T.V.3
  • 30
    • 0036208475 scopus 로고    scopus 로고
    • Functional expression of a novel ginsenoside Rf binding protein from rat brain mRNA in Xenopus laevis oocytes
    • Choi S, Jung SY, Ko YS, Koh SR, Rhim H, Nah SY. Functional expression of a novel ginsenoside Rf binding protein from rat brain mRNA in Xenopus laevis oocytes. Mol Pharmacol 2002; 61: 928-35.
    • (2002) Mol Pharmacol , vol.61 , pp. 928-935
    • Choi, S.1    Jung, S.Y.2    Ko, Y.S.3    Koh, S.R.4    Rhim, H.5    Nah, S.Y.6
  • 32
    • 0033945753 scopus 로고    scopus 로고
    • Potassium channel openers as potential therapeutic weapons in ion channel disease
    • Lawson, K. Potassium channel openers as potential therapeutic weapons in ion channel disease. Kidney Int 2000; 57: 838-45.
    • (2000) Kidney Int , vol.57 , pp. 838-845
    • Lawson, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.