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Volumn 120, Issue 12, 2012, Pages 941-949

Viral infections and molecular mimicry in type 1 diabetes

Author keywords

Autoimmunity; Infection; Mimicry; T cells; Type 1 diabetes; Viruses

Indexed keywords

ALTERED PEPTIDE LIGAND; LIGAND; UNCLASSIFIED DRUG;

EID: 84869082042     PISSN: 09034641     EISSN: 16000463     Source Type: Journal    
DOI: 10.1111/apm.12011     Document Type: Article
Times cited : (71)

References (53)
  • 3
    • 0035076548 scopus 로고    scopus 로고
    • Heterogeneity of type I diabetes: analysis of monozygotic twins in Great Britain and the United States
    • Redondo MJ, Yu L, Hawa M, Mackenzie T, Pyke DA, Eisenbarth GS, et al. Heterogeneity of type I diabetes: analysis of monozygotic twins in Great Britain and the United States. Diabetologia 2001;44:354-62.
    • (2001) Diabetologia , vol.44 , pp. 354-362
    • Redondo, M.J.1    Yu, L.2    Hawa, M.3    Mackenzie, T.4    Pyke, D.A.5    Eisenbarth, G.S.6
  • 5
    • 67049159857 scopus 로고    scopus 로고
    • Incidence trends for childhood type 1 diabetes in Europe during 1989-2003 and predicted new cases 2005-20: a multicentre prospective registration study
    • Patterson CC, Dahlquist GG, Gyurus E, Green A, Soltesz G. Incidence trends for childhood type 1 diabetes in Europe during 1989-2003 and predicted new cases 2005-20: a multicentre prospective registration study. Lancet 2009;373:2027-33.
    • (2009) Lancet , vol.373 , pp. 2027-2033
    • Patterson, C.C.1    Dahlquist, G.G.2    Gyurus, E.3    Green, A.4    Soltesz, G.5
  • 6
    • 79951983776 scopus 로고    scopus 로고
    • Enterovirus infection and type 1 diabetes mellitus: systematic review and meta-analysis of observational molecular studies
    • Yeung WC, Rawlinson WD, Craig ME. Enterovirus infection and type 1 diabetes mellitus: systematic review and meta-analysis of observational molecular studies. BMJ 2011;342:d35.
    • (2011) BMJ , vol.342
    • Yeung, W.C.1    Rawlinson, W.D.2    Craig, M.E.3
  • 8
    • 15244341417 scopus 로고    scopus 로고
    • A viral epitope that mimics a self antigen can accelerate but not initiate autoimmune diabetes
    • Christen U, Edelmann KH, McGavern DB, Wolfe T, Coon B, Teague MK, et al. A viral epitope that mimics a self antigen can accelerate but not initiate autoimmune diabetes. J Clin Investig 2004;114:1290-8.
    • (2004) J Clin Investig , vol.114 , pp. 1290-1298
    • Christen, U.1    Edelmann, K.H.2    McGavern, D.B.3    Wolfe, T.4    Coon, B.5    Teague, M.K.6
  • 9
    • 67650999438 scopus 로고    scopus 로고
    • Immunoregulatory mechanisms triggered by viral infections protect from type 1 diabetes in mice
    • Filippi CM, Estes EA, Oldham JE, von Herrath MG. Immunoregulatory mechanisms triggered by viral infections protect from type 1 diabetes in mice. J Clin Investig 2009;119:1515-23.
    • (2009) J Clin Investig , vol.119 , pp. 1515-1523
    • Filippi, C.M.1    Estes, E.A.2    Oldham, J.E.3    von Herrath, M.G.4
  • 10
    • 0036889147 scopus 로고    scopus 로고
    • Toward testing the hypothesis that group B coxsackieviruses (CVB) trigger insulin-dependent diabetes: inoculating nonobese diabetic mice with CVB markedly lowers diabetes incidence
    • Tracy S, Drescher KM, Chapman NM, Kim KS, Carson SD, Pirruccello S, et al. Toward testing the hypothesis that group B coxsackieviruses (CVB) trigger insulin-dependent diabetes: inoculating nonobese diabetic mice with CVB markedly lowers diabetes incidence. J Virol 2002;76:12097-111.
    • (2002) J Virol , vol.76 , pp. 12097-12111
    • Tracy, S.1    Drescher, K.M.2    Chapman, N.M.3    Kim, K.S.4    Carson, S.D.5    Pirruccello, S.6
  • 12
    • 79551469699 scopus 로고    scopus 로고
    • Genetics of type 1 diabetes
    • Steck AK, Rewers MJ. Genetics of type 1 diabetes. Clin Chem 2011;57:176-85.
    • (2011) Clin Chem , vol.57 , pp. 176-185
    • Steck, A.K.1    Rewers, M.J.2
  • 13
    • 33745240931 scopus 로고    scopus 로고
    • A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region
    • Smyth DJ, Cooper JD, Bailey R, Field S, Burren O, Smink LJ, et al. A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region. Nat Genet 2006;38:617-9.
    • (2006) Nat Genet , vol.38 , pp. 617-619
    • Smyth, D.J.1    Cooper, J.D.2    Bailey, R.3    Field, S.4    Burren, O.5    Smink, L.J.6
  • 14
    • 65249131713 scopus 로고    scopus 로고
    • Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes
    • Nejentsev S, Walker N, Riches D, Egholm M, Todd JA. Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes. Science 2009;324:387-9.
    • (2009) Science , vol.324 , pp. 387-389
    • Nejentsev, S.1    Walker, N.2    Riches, D.3    Egholm, M.4    Todd, J.A.5
  • 15
    • 0026761212 scopus 로고
    • Coxsackievirus B4 infection alters thymic, splenic, and peripheral lymphocyte repertoire preceding onset of hyperglycemia in mice
    • Chatterjee NK, Hou J, Dockstader P, Charbonneau T. Coxsackievirus B4 infection alters thymic, splenic, and peripheral lymphocyte repertoire preceding onset of hyperglycemia in mice. J Med Virol 1992;38:124-31.
    • (1992) J Med Virol , vol.38 , pp. 124-131
    • Chatterjee, N.K.1    Hou, J.2    Dockstader, P.3    Charbonneau, T.4
  • 16
    • 4444348507 scopus 로고    scopus 로고
    • Coxsackievirus B4 infection of human fetal thymus cells
    • Brilot F, Geenen V, Hober D, Stoddart CA. Coxsackievirus B4 infection of human fetal thymus cells. J Virol 2004;78:9854-61.
    • (2004) J Virol , vol.78 , pp. 9854-9861
    • Brilot, F.1    Geenen, V.2    Hober, D.3    Stoddart, C.A.4
  • 17
    • 33847373481 scopus 로고    scopus 로고
    • No alterations in the frequency of FOXP3+ regulatory T-cells in type 1 diabetes
    • Brusko T, Wasserfall C, McGrail K, Schatz R, Viener HL, Schatz D, et al. No alterations in the frequency of FOXP3+ regulatory T-cells in type 1 diabetes. Diabetes 2007;56:604-12.
    • (2007) Diabetes , vol.56 , pp. 604-612
    • Brusko, T.1    Wasserfall, C.2    McGrail, K.3    Schatz, R.4    Viener, H.L.5    Schatz, D.6
  • 18
    • 34247627376 scopus 로고    scopus 로고
    • Coxsackie B4 virus infection of beta cells and natural killer cell insulitis in recent-onset type 1 diabetic patients
    • Dotta F, Censini S, van Halteren AG, Marselli L, Masini M, Dionisi S, et al. Coxsackie B4 virus infection of beta cells and natural killer cell insulitis in recent-onset type 1 diabetic patients. Proc Natl Acad Sci USA 2007;104:5115-20.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 5115-5120
    • Dotta, F.1    Censini, S.2    van Halteren, A.G.3    Marselli, L.4    Masini, M.5    Dionisi, S.6
  • 19
    • 33846785541 scopus 로고    scopus 로고
    • Effects on isolated human pancreatic islet cells after infection with strains of enterovirus isolated at clinical presentation of type 1 diabetes
    • Elshebani A, Olsson A, Westman J, Tuvemo T, Korsgren O, Frisk G. Effects on isolated human pancreatic islet cells after infection with strains of enterovirus isolated at clinical presentation of type 1 diabetes. Virus Res 2007;124:193-203.
    • (2007) Virus Res , vol.124 , pp. 193-203
    • Elshebani, A.1    Olsson, A.2    Westman, J.3    Tuvemo, T.4    Korsgren, O.5    Frisk, G.6
  • 20
    • 66449116276 scopus 로고    scopus 로고
    • The prevalence of enteroviral capsid protein vp1 immunostaining in pancreatic islets in human type 1 diabetes
    • Richardson SJ, Willcox A, Bone AJ, Foulis AK, Morgan NG. The prevalence of enteroviral capsid protein vp1 immunostaining in pancreatic islets in human type 1 diabetes. Diabetologia 2009;52:1143-51.
    • (2009) Diabetologia , vol.52 , pp. 1143-1151
    • Richardson, S.J.1    Willcox, A.2    Bone, A.J.3    Foulis, A.K.4    Morgan, N.G.5
  • 21
    • 34848851427 scopus 로고    scopus 로고
    • Modestly increased beta cell apoptosis but no increased beta cell replication in recent-onset type 1 diabetic patients who died of diabetic ketoacidosis
    • Butler AE, Galasso R, Meier JJ, Basu R, Rizza RA, Butler PC. Modestly increased beta cell apoptosis but no increased beta cell replication in recent-onset type 1 diabetic patients who died of diabetic ketoacidosis. Diabetologia 2007;50:2323-31.
    • (2007) Diabetologia , vol.50 , pp. 2323-2331
    • Butler, A.E.1    Galasso, R.2    Meier, J.J.3    Basu, R.4    Rizza, R.A.5    Butler, P.C.6
  • 22
    • 0034598761 scopus 로고    scopus 로고
    • A novel subtype of type 1 diabetes mellitus characterized by a rapid onset and an absence of diabetes-related antibodies. Osaka IDDM Study Group
    • Imagawa A, Hanafusa T, Miyagawa J, Matsuzawa Y. A novel subtype of type 1 diabetes mellitus characterized by a rapid onset and an absence of diabetes-related antibodies. Osaka IDDM Study Group. N Engl J Med 2000;342:301-7.
    • (2000) N Engl J Med , vol.342 , pp. 301-307
    • Imagawa, A.1    Hanafusa, T.2    Miyagawa, J.3    Matsuzawa, Y.4
  • 23
    • 70349651422 scopus 로고    scopus 로고
    • Enterovirus infection, CXC chemokine ligand 10 (CXCL10), and CXCR3 circuit: a mechanism of accelerated beta-cell failure in fulminant type 1 diabetes
    • Tanaka S, Nishida Y, Aida K, Maruyama T, Shimada A, Suzuki M, et al. Enterovirus infection, CXC chemokine ligand 10 (CXCL10), and CXCR3 circuit: a mechanism of accelerated beta-cell failure in fulminant type 1 diabetes. Diabetes 2009;58:2285-91.
    • (2009) Diabetes , vol.58 , pp. 2285-2291
    • Tanaka, S.1    Nishida, Y.2    Aida, K.3    Maruyama, T.4    Shimada, A.5    Suzuki, M.6
  • 24
    • 43349095303 scopus 로고    scopus 로고
    • Persistent coxsackievirus infection: enterovirus persistence in chronic myocarditis and dilated cardiomyopathy
    • Chapman NM, Kim KS. Persistent coxsackievirus infection: enterovirus persistence in chronic myocarditis and dilated cardiomyopathy. Curr Top Microbiol Immunol 2008;323:275-92.
    • (2008) Curr Top Microbiol Immunol , vol.323 , pp. 275-292
    • Chapman, N.M.1    Kim, K.S.2
  • 25
    • 0023520177 scopus 로고
    • Immunoreactive alpha-interferon in insulin-secreting beta cells in type 1 diabetes mellitus
    • Foulis AK, Farquharson MA, Meager A. Immunoreactive alpha-interferon in insulin-secreting beta cells in type 1 diabetes mellitus. Lancet 1987;2:1423-7.
    • (1987) Lancet , vol.2 , pp. 1423-1427
    • Foulis, A.K.1    Farquharson, M.A.2    Meager, A.3
  • 27
    • 0036141519 scopus 로고    scopus 로고
    • Presented antigen from damaged pancreatic beta cells activates autoreactive T cells in virus-mediated autoimmune diabetes
    • Horwitz MS, Ilic A, Fine C, Rodriguez E, Sarvetnick N. Presented antigen from damaged pancreatic beta cells activates autoreactive T cells in virus-mediated autoimmune diabetes. J Clin Investig 2002;109:79-87.
    • (2002) J Clin Investig , vol.109 , pp. 79-87
    • Horwitz, M.S.1    Ilic, A.2    Fine, C.3    Rodriguez, E.4    Sarvetnick, N.5
  • 28
    • 70349745490 scopus 로고    scopus 로고
    • T cell islet accumulation in type 1 diabetes is a tightly regulated, cell-autonomous event
    • Lennon GP, Bettini M, Burton AR, Vincent E, Arnold PY, Santamaria P, et al. T cell islet accumulation in type 1 diabetes is a tightly regulated, cell-autonomous event. Immunity 2009;31:643-53.
    • (2009) Immunity , vol.31 , pp. 643-653
    • Lennon, G.P.1    Bettini, M.2    Burton, A.R.3    Vincent, E.4    Arnold, P.Y.5    Santamaria, P.6
  • 29
    • 0024533021 scopus 로고
    • Molecular mimicry as a mechanism for virus-induced autoimmunity
    • Fujinami RS, Oldstone MB. Molecular mimicry as a mechanism for virus-induced autoimmunity. Immunol Res 1989;8:3-15.
    • (1989) Immunol Res , vol.8 , pp. 3-15
    • Fujinami, R.S.1    Oldstone, M.B.2
  • 30
    • 0032171644 scopus 로고    scopus 로고
    • A very high level of crossreactivity is an essential feature of the T-cell receptor
    • Mason D. A very high level of crossreactivity is an essential feature of the T-cell receptor. Immunol Today 1998;19:395-404.
    • (1998) Immunol Today , vol.19 , pp. 395-404
    • Mason, D.1
  • 31
    • 0035554950 scopus 로고    scopus 로고
    • Autoimmunity provoked by infection: how good is the case for T cell epitope mimicry?
    • Benoist C., Mathis D. Autoimmunity provoked by infection: how good is the case for T cell epitope mimicry? Nat Immunol 2001;2:797-801.
    • (2001) Nat Immunol , vol.2 , pp. 797-801
    • Benoist, C.1    Mathis, D.2
  • 32
    • 77249113181 scopus 로고    scopus 로고
    • Rheumatic fever and rheumatic heart disease: cellular mechanisms leading autoimmune reactivity and disease
    • Guilherme L, Kalil J. Rheumatic fever and rheumatic heart disease: cellular mechanisms leading autoimmune reactivity and disease. J Clin Immunol 2010;30:17-23.
    • (2010) J Clin Immunol , vol.30 , pp. 17-23
    • Guilherme, L.1    Kalil, J.2
  • 33
    • 0842324619 scopus 로고    scopus 로고
    • The Guillain-Barre syndrome: a true case of molecular mimicry
    • Ang CW, Jacobs BC, Laman JD. The Guillain-Barre syndrome: a true case of molecular mimicry. Trends Immunol 2004;25:61-6.
    • (2004) Trends Immunol , vol.25 , pp. 61-66
    • Ang, C.W.1    Jacobs, B.C.2    Laman, J.D.3
  • 34
    • 0023182772 scopus 로고
    • Autoantibodies to HLA B27 in the sera of HLA B27 patients with ankylosing spondylitis and Reiter's syndrome. Molecular mimicry with Klebsiella pneumoniae as potential mechanism of autoimmune disease
    • Schwimmbeck PL, Yu DT, Oldstone MB. Autoantibodies to HLA B27 in the sera of HLA B27 patients with ankylosing spondylitis and Reiter's syndrome. Molecular mimicry with Klebsiella pneumoniae as potential mechanism of autoimmune disease. J Exp Med 1987;166:173-81.
    • (1987) J Exp Med , vol.166 , pp. 173-181
    • Schwimmbeck, P.L.1    Yu, D.T.2    Oldstone, M.B.3
  • 35
    • 0027934724 scopus 로고
    • Identification of the dihydrolipoamide acetyltransferase subunit of the human pyruvate dehydrogenase complex as an autoantigen in halothane hepatitis. Molecular mimicry of trifluoroacetyl-lysine by lipoic acid
    • Christen U, Quinn J, Yeaman SJ, Kenna JG, Clarke JB, Gandolfi AJ, et al. Identification of the dihydrolipoamide acetyltransferase subunit of the human pyruvate dehydrogenase complex as an autoantigen in halothane hepatitis. Molecular mimicry of trifluoroacetyl-lysine by lipoic acid. Eur J Biochem 1994;223:1035-47.
    • (1994) Eur J Biochem , vol.223 , pp. 1035-1047
    • Christen, U.1    Quinn, J.2    Yeaman, S.J.3    Kenna, J.G.4    Clarke, J.B.5    Gandolfi, A.J.6
  • 36
    • 0028007192 scopus 로고
    • Cellular immunity to a determinant common to glutamate decarboxylase and coxsackie virus in insulin-dependent diabetes
    • Atkinson MA, Bowman MA, Campbell L, Darrow BL, Kaufman DL, Maclaren NK. Cellular immunity to a determinant common to glutamate decarboxylase and coxsackie virus in insulin-dependent diabetes. J Clin Investig 1994;94:2125-9.
    • (1994) J Clin Investig , vol.94 , pp. 2125-2129
    • Atkinson, M.A.1    Bowman, M.A.2    Campbell, L.3    Darrow, B.L.4    Kaufman, D.L.5    Maclaren, N.K.6
  • 37
    • 0035044922 scopus 로고    scopus 로고
    • Molecular mimicry in type 1 diabetes mellitus revisited: T-cell clones to GAD65 peptides with sequence homology to Coxsackie or proinsulin peptides do not crossreact with homologous counterpart
    • Schloot NC, Willemen SJ, Duinkerken G, Drijfhout JW, de Vries RR, Roep BO. Molecular mimicry in type 1 diabetes mellitus revisited: T-cell clones to GAD65 peptides with sequence homology to Coxsackie or proinsulin peptides do not crossreact with homologous counterpart. Hum Immunol 2001;62:299-309.
    • (2001) Hum Immunol , vol.62 , pp. 299-309
    • Schloot, N.C.1    Willemen, S.J.2    Duinkerken, G.3    Drijfhout, J.W.4    de Vries, R.R.5    Roep, B.O.6
  • 39
    • 0036158287 scopus 로고    scopus 로고
    • Enterovirus infection can induce immune responses that cross-react with beta-cell autoantigen tyrosine phosphatase IA-2/IAR
    • Harkonen T, Lankinen H, Davydova B, Hovi T, Roivainen M. Enterovirus infection can induce immune responses that cross-react with beta-cell autoantigen tyrosine phosphatase IA-2/IAR. J Med Virol 2002;66:340-50.
    • (2002) J Med Virol , vol.66 , pp. 340-350
    • Harkonen, T.1    Lankinen, H.2    Davydova, B.3    Hovi, T.4    Roivainen, M.5
  • 40
    • 77949889458 scopus 로고    scopus 로고
    • Evidence for molecular mimicry between human T cell epitopes in rotavirus and pancreatic islet autoantigens
    • Honeyman MC, Stone NL, Falk BA, Nepom G, Harrison LC. Evidence for molecular mimicry between human T cell epitopes in rotavirus and pancreatic islet autoantigens. J Immunol 2010;184:2204-10.
    • (2010) J Immunol , vol.184 , pp. 2204-2210
    • Honeyman, M.C.1    Stone, N.L.2    Falk, B.A.3    Nepom, G.4    Harrison, L.C.5
  • 41
    • 0025755292 scopus 로고
    • Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice
    • Ohashi PS, Oehen S, Buerki K, Pircher H, Ohashi CT, Odermatt B, et al. Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice. Cell 1991;65:305-17.
    • (1991) Cell , vol.65 , pp. 305-317
    • Ohashi, P.S.1    Oehen, S.2    Buerki, K.3    Pircher, H.4    Ohashi, C.T.5    Odermatt, B.6
  • 42
    • 0025754853 scopus 로고
    • Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model: role of anti-self (virus) immune response
    • Oldstone MB, Nerenberg M, Southern P, Price J, Lewicki H. Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model: role of anti-self (virus) immune response. Cell 1991;65:319-31.
    • (1991) Cell , vol.65 , pp. 319-331
    • Oldstone, M.B.1    Nerenberg, M.2    Southern, P.3    Price, J.4    Lewicki, H.5
  • 43
    • 0034669927 scopus 로고    scopus 로고
    • Neither B lymphocytes nor antibodies directed against self antigens of the islets of Langerhans are required for development of virus-induced autoimmune diabetes
    • Holz A, Dyrberg T, Hagopian W, Homann D, von Herrath M, Oldstone MB. Neither B lymphocytes nor antibodies directed against self antigens of the islets of Langerhans are required for development of virus-induced autoimmune diabetes. J Immunol 2000;165:5945-53.
    • (2000) J Immunol , vol.165 , pp. 5945-5953
    • Holz, A.1    Dyrberg, T.2    Hagopian, W.3    Homann, D.4    von Herrath, M.5    Oldstone, M.B.6
  • 44
    • 0034011436 scopus 로고    scopus 로고
    • Virus-induced diabetes in a transgenic model: role of cross-reacting viruses and quantitation of effector T cells needed to cause disease
    • Sevilla N, Homann D, von Herrath M, Rodriguez F, Harkins S, Whitton JL, et al. Virus-induced diabetes in a transgenic model: role of cross-reacting viruses and quantitation of effector T cells needed to cause disease. J Virol 2000;74:3284-92.
    • (2000) J Virol , vol.74 , pp. 3284-3292
    • Sevilla, N.1    Homann, D.2    von Herrath, M.3    Rodriguez, F.4    Harkins, S.5    Whitton, J.L.6
  • 45
    • 1242270574 scopus 로고    scopus 로고
    • Induction, acceleration or prevention of autoimmunity by molecular mimicry
    • Christen U, von Herrath MG. Induction, acceleration or prevention of autoimmunity by molecular mimicry. Mol Immunol 2004;40:1113-20.
    • (2004) Mol Immunol , vol.40 , pp. 1113-1120
    • Christen, U.1    von Herrath, M.G.2
  • 46
    • 0029933309 scopus 로고    scopus 로고
    • Altered peptide ligand-induced partial T cell activation: molecular mechanisms and role in T cell biology
    • Sloan-Lancaster J, Allen PM. Altered peptide ligand-induced partial T cell activation: molecular mechanisms and role in T cell biology. Annu Rev Immunol 1996;14:1-27.
    • (1996) Annu Rev Immunol , vol.14 , pp. 1-27
    • Sloan-Lancaster, J.1    Allen, P.M.2
  • 47
    • 70449412682 scopus 로고    scopus 로고
    • No effect of the altered peptide ligand NBI-6024 on beta-cell residual function and insulin needs in new-onset type 1 diabetes
    • Walter M, Philotheou A, Bonnici F, Ziegler AG, Jimenez R. No effect of the altered peptide ligand NBI-6024 on beta-cell residual function and insulin needs in new-onset type 1 diabetes. Diabetes Care 2009;32:2036-40.
    • (2009) Diabetes Care , vol.32 , pp. 2036-2040
    • Walter, M.1    Philotheou, A.2    Bonnici, F.3    Ziegler, A.G.4    Jimenez, R.5
  • 48
    • 0022617990 scopus 로고
    • Type I diabetes mellitus. A chronic autoimmune disease
    • Eisenbarth GS. Type I diabetes mellitus. A chronic autoimmune disease. N Engl J Med 1986;314:1360-8.
    • (1986) N Engl J Med , vol.314 , pp. 1360-1368
    • Eisenbarth, G.S.1
  • 49
    • 1842613450 scopus 로고    scopus 로고
    • Microorganisms and autoimmunity: making the barren field fertile?
    • von Herrath MG, Fujinami RS, Whitton JL. Microorganisms and autoimmunity: making the barren field fertile? Nat Rev Microbiol 2003;1:151-7.
    • (2003) Nat Rev Microbiol , vol.1 , pp. 151-157
    • von Herrath, M.G.1    Fujinami, R.S.2    Whitton, J.L.3
  • 50
    • 7044254968 scopus 로고    scopus 로고
    • Coxsackievirus B3 infection and type 1 diabetes development in NOD mice: insulitis determines susceptibility of pancreatic islets to virus infection
    • Drescher KM, Kono K, Bopegamage S, Carson SD, Tracy S. Coxsackievirus B3 infection and type 1 diabetes development in NOD mice: insulitis determines susceptibility of pancreatic islets to virus infection. Virology 2004;329:381-94.
    • (2004) Virology , vol.329 , pp. 381-394
    • Drescher, K.M.1    Kono, K.2    Bopegamage, S.3    Carson, S.D.4    Tracy, S.5
  • 51
    • 0034083713 scopus 로고    scopus 로고
    • Acceleration of type 1 diabetes by a coxsackievirus infection requires a preexisting critical mass of autoreactive T-cells in pancreatic islets
    • Serreze DV, Ottendorfer EW, Ellis TM, Gauntt CJ, Atkinson MA. Acceleration of type 1 diabetes by a coxsackievirus infection requires a preexisting critical mass of autoreactive T-cells in pancreatic islets. Diabetes 2000;49:708-11.
    • (2000) Diabetes , vol.49 , pp. 708-711
    • Serreze, D.V.1    Ottendorfer, E.W.2    Ellis, T.M.3    Gauntt, C.J.4    Atkinson, M.A.5
  • 53
    • 78650070483 scopus 로고    scopus 로고
    • Enterovirus infection and progression from islet autoimmunity to type 1 diabetes: the Diabetes and Autoimmunity Study in the Young (DAISY)
    • Stene LC, Oikarinen S, Hyoty H, Barriga KJ, Norris JM, Klingensmith G, et al. Enterovirus infection and progression from islet autoimmunity to type 1 diabetes: the Diabetes and Autoimmunity Study in the Young (DAISY). Diabetes 2010;59:3174-80.
    • (2010) Diabetes , vol.59 , pp. 3174-3180
    • Stene, L.C.1    Oikarinen, S.2    Hyoty, H.3    Barriga, K.J.4    Norris, J.M.5    Klingensmith, G.6


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