Contribution of oligomerization to the anti-HIV-1 properties of SAMHD1

Retrovirology

Volumn 10, Issue 1, 2013, Pages

  Brandariz Nuñez, Alberto ^a   Valle Casuso, Jose C ^a   White, Tommy E ^a   Nguyen, Laura ^b   Bhattacharya, Akash ^c   Wang, Zhonghua ^c   Demeler, Borries ^c   Amie, Sarah ^b   Knowlton, Caitlin ^b   Kim, Baek ^b   Ivanov, Dmitri N ^c   Diaz Griffero, Felipe ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

Deoxynucleotides; HIV 1; Nuclease activity; Oligomerization; Restriction; SAMHD1; Tetramer

Indexed keywords

CELL PROTEIN; DEOXYGUANOSINE TRIPHOSPHATE; DGTP REGULATED DEOXYNUCLEOTIDE TRIPHOSPHOHYDROLASE; HYDROLASE; LEUCINE; NUCLEASE; PROTEIN SAMHD1; PROTEIN VARIANT; SERINE; TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HYDROPHOBICITY; IMMUNOPRECIPITATION; IN VITRO STUDY; MAMMAL CELL; MUTATION; NONHUMAN; OLIGOMERIZATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STABILITY; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS; VIRUS CELL INTERACTION; VIRUS INHIBITION;

BACTERIA (MICROORGANISMS); HUMAN IMMUNODEFICIENCY VIRUS 1; MAMMALIA;

CELL LINE; CRYSTALLOGRAPHY, X-RAY; DNA MUTATIONAL ANALYSIS; HIV-1; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNOPRECIPITATION; MODELS, MOLECULAR; MONOMERIC GTP-BINDING PROTEINS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION;

EID: 84887284211     PISSN: None     EISSN: 17424690     Source Type: Journal    
DOI: 10.1186/1742-4690-10-131     Document Type: Article

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