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Volumn 9, Issue 10, 2013, Pages

The DAF-16/FOXO Transcription Factor Functions as a Regulator of Epidermal Innate Immunity

Author keywords

[No Author keywords available]

Indexed keywords

REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR DAF 16; TRANSCRIPTION FACTOR FOXO;

EID: 84887276664     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1003660     Document Type: Article
Times cited : (60)

References (64)
  • 1
    • 0036164933 scopus 로고    scopus 로고
    • Caenorhabditis elegans as a host for the study of host-pathogen interactions
    • Aballay A, Ausubel FM, (2002) Caenorhabditis elegans as a host for the study of host-pathogen interactions. Curr Opin Microbiol 5: 97-101.
    • (2002) Curr Opin Microbiol , vol.5 , pp. 97-101
    • Aballay, A.1    Ausubel, F.M.2
  • 2
    • 72949096858 scopus 로고    scopus 로고
    • Evolution of host innate defence: insights from Caenorhabditis elegans and primitive invertebrates
    • Irazoqui JE, Urbach JM, Ausubel FM, (2010) Evolution of host innate defence: insights from Caenorhabditis elegans and primitive invertebrates. Nat Rev Immunol 10: 47-58.
    • (2010) Nat Rev Immunol , vol.10 , pp. 47-58
    • Irazoqui, J.E.1    Urbach, J.M.2    Ausubel, F.M.3
  • 3
    • 0030813398 scopus 로고    scopus 로고
    • daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans
    • Kimura KD, Tissenbaum HA, Liu Y, Ruvkun G, (1997) daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science 277: 942-946.
    • (1997) Science , vol.277 , pp. 942-946
    • Kimura, K.D.1    Tissenbaum, H.A.2    Liu, Y.3    Ruvkun, G.4
  • 4
    • 0038047438 scopus 로고    scopus 로고
    • Long-lived C. elegans daf-2 mutants are resistant to bacterial pathogens
    • Garsin DA, Villanueva JM, Begun J, Kim DH, Sifri CD, et al. (2003) Long-lived C. elegans daf-2 mutants are resistant to bacterial pathogens. Science 300: 1921.
    • (2003) Science , vol.300 , pp. 1921
    • Garsin, D.A.1    Villanueva, J.M.2    Begun, J.3    Kim, D.H.4    Sifri, C.D.5
  • 5
    • 0034967720 scopus 로고    scopus 로고
    • Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling
    • Lin K, Hsin H, Libina N, Kenyon C, (2001) Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling. Nat Genet 28: 139-145.
    • (2001) Nat Genet , vol.28 , pp. 139-145
    • Lin, K.1    Hsin, H.2    Libina, N.3    Kenyon, C.4
  • 6
    • 0035846604 scopus 로고    scopus 로고
    • daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans
    • Henderson ST, Johnson TE, (2001) daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans. Curr Biol 11: 1975-1980.
    • (2001) Curr Biol , vol.11 , pp. 1975-1980
    • Henderson, S.T.1    Johnson, T.E.2
  • 7
    • 55449092047 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa suppresses host immunity by activating the DAF-2 insulin-like signaling pathway in Caenorhabditis elegans
    • Evans EA, Kawli T, Tan MW, (2008) Pseudomonas aeruginosa suppresses host immunity by activating the DAF-2 insulin-like signaling pathway in Caenorhabditis elegans. PLoS Pathog 4: e1000175.
    • (2008) PLoS Pathog , vol.4
    • Evans, E.A.1    Kawli, T.2    Tan, M.W.3
  • 8
    • 0042092531 scopus 로고    scopus 로고
    • Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
    • Murphy CT, McCarroll SA, Bargmann CI, Fraser A, Kamath RS, et al. (2003) Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature 424: 277-283.
    • (2003) Nature , vol.424 , pp. 277-283
    • Murphy, C.T.1    McCarroll, S.A.2    Bargmann, C.I.3    Fraser, A.4    Kamath, R.S.5
  • 9
    • 33748346435 scopus 로고    scopus 로고
    • Heat-shock transcription factor (HSF)-1 pathway required for Caenorhabditis elegans immunity
    • Singh V, Aballay A, (2006) Heat-shock transcription factor (HSF)-1 pathway required for Caenorhabditis elegans immunity. Proc Natl Acad Sci U S A 103: 13092-13097.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 13092-13097
    • Singh, V.1    Aballay, A.2
  • 10
    • 75149154705 scopus 로고    scopus 로고
    • FOXO-dependent regulation of innate immune homeostasis
    • Becker T, Loch G, Beyer M, Zinke I, Aschenbrenner AC, et al. (2010) FOXO-dependent regulation of innate immune homeostasis. Nature 463: 369-373.
    • (2010) Nature , vol.463 , pp. 369-373
    • Becker, T.1    Loch, G.2    Beyer, M.3    Zinke, I.4    Aschenbrenner, A.C.5
  • 11
    • 33751382748 scopus 로고    scopus 로고
    • p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans
    • Troemel ER, Chu SW, Reinke V, Lee SS, Ausubel FM, et al. (2006) p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans. PLoS Genet 2: e183.
    • (2006) PLoS Genet , vol.2
    • Troemel, E.R.1    Chu, S.W.2    Reinke, V.3    Lee, S.S.4    Ausubel, F.M.5
  • 12
    • 65549102852 scopus 로고    scopus 로고
    • Conditioning protects C. elegans from lethal effects of enteropathogenic E. coli by activating genes that regulate lifespan and innate immunity
    • Anyanful A, Easley KA, Benian GM, Kalman D, (2009) Conditioning protects C. elegans from lethal effects of enteropathogenic E. coli by activating genes that regulate lifespan and innate immunity. Cell Host Microbe 5: 450-462.
    • (2009) Cell Host Microbe , vol.5 , pp. 450-462
    • Anyanful, A.1    Easley, K.A.2    Benian, G.M.3    Kalman, D.4
  • 13
    • 84862806982 scopus 로고    scopus 로고
    • Activation of the Caenorhabditis elegans FOXO family transcription factor DAF-16 by pathogenic Bacillus thuringiensis
    • Wang J, Nakad R, Schulenburg H, (2012) Activation of the Caenorhabditis elegans FOXO family transcription factor DAF-16 by pathogenic Bacillus thuringiensis. Dev Comp Immunol 37: 193-201.
    • (2012) Dev Comp Immunol , vol.37 , pp. 193-201
    • Wang, J.1    Nakad, R.2    Schulenburg, H.3
  • 14
    • 33749014641 scopus 로고    scopus 로고
    • A conserved role for a GATA transcription factor in regulating epithelial innate immune responses
    • Shapira M, Hamlin BJ, Rong J, Chen K, Ronen M, et al. (2006) A conserved role for a GATA transcription factor in regulating epithelial innate immune responses. Proc Natl Acad Sci U S A 103: 14086-14091.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 14086-14091
    • Shapira, M.1    Hamlin, B.J.2    Rong, J.3    Chen, K.4    Ronen, M.5
  • 15
    • 23744469419 scopus 로고    scopus 로고
    • Paralysis and killing of Caenorhabditis elegans by enteropathogenic Escherichia coli requires the bacterial tryptophanase gene
    • Anyanful A, Dolan-Livengood JM, Lewis T, Sheth S, Dezalia MN, et al. (2005) Paralysis and killing of Caenorhabditis elegans by enteropathogenic Escherichia coli requires the bacterial tryptophanase gene. Mol Microbiol 57: 988-1007.
    • (2005) Mol Microbiol , vol.57 , pp. 988-1007
    • Anyanful, A.1    Dolan-Livengood, J.M.2    Lewis, T.3    Sheth, S.4    Dezalia, M.N.5
  • 16
    • 34249809714 scopus 로고    scopus 로고
    • The role of Caenorhabditis elegans insulin-like signaling in the behavioral avoidance of pathogenic Bacillus thuringiensis
    • Hasshoff M, Bohnisch C, Tonn D, Hasert B, Schulenburg H, (2007) The role of Caenorhabditis elegans insulin-like signaling in the behavioral avoidance of pathogenic Bacillus thuringiensis. FASEB J 21: 1801-1812.
    • (2007) FASEB J , vol.21 , pp. 1801-1812
    • Hasshoff, M.1    Bohnisch, C.2    Tonn, D.3    Hasert, B.4    Schulenburg, H.5
  • 17
    • 79959814514 scopus 로고    scopus 로고
    • Candida albicans infection of Caenorhabditis elegans induces antifungal immune defenses
    • Pukkila-Worley R, Ausubel FM, Mylonakis E, (2011) Candida albicans infection of Caenorhabditis elegans induces antifungal immune defenses. PLoS Pathog 7: e1002074.
    • (2011) PLoS Pathog , vol.7
    • Pukkila-Worley, R.1    Ausubel, F.M.2    Mylonakis, E.3
  • 18
    • 2442664007 scopus 로고    scopus 로고
    • TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM
    • Couillault C, Pujol N, Reboul J, Sabatier L, Guichou JF, et al. (2004) TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM. Nat Immunol 5: 488-494.
    • (2004) Nat Immunol , vol.5 , pp. 488-494
    • Couillault, C.1    Pujol, N.2    Reboul, J.3    Sabatier, L.4    Guichou, J.F.5
  • 19
    • 41549104500 scopus 로고    scopus 로고
    • Distinct innate immune responses to infection and wounding in the C. elegans epidermis
    • Pujol N, Cypowyj S, Ziegler K, Millet A, Astrain A, et al. (2008) Distinct innate immune responses to infection and wounding in the C. elegans epidermis. Curr Biol 18: 481-489.
    • (2008) Curr Biol , vol.18 , pp. 481-489
    • Pujol, N.1    Cypowyj, S.2    Ziegler, K.3    Millet, A.4    Astrain, A.5
  • 20
    • 60849119836 scopus 로고    scopus 로고
    • Negative regulation of Caenorhabditis elegans epidermal damage responses by death-associated protein kinase
    • Tong A, Lynn G, Ngo V, Wong D, Moseley SL, et al. (2009) Negative regulation of Caenorhabditis elegans epidermal damage responses by death-associated protein kinase. Proc Natl Acad Sci U S A 106: 1457-1461.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 1457-1461
    • Tong, A.1    Lynn, G.2    Ngo, V.3    Wong, D.4    Moseley, S.L.5
  • 21
    • 80053445520 scopus 로고    scopus 로고
    • Genomic and proteomic analyses of the fungus Arthrobotrys oligospora provide insights into nematode-trap formation
    • Yang J, Wang L, Ji X, Feng Y, Li X, et al. (2011) Genomic and proteomic analyses of the fungus Arthrobotrys oligospora provide insights into nematode-trap formation. PLoS Pathog 7: e1002179.
    • (2011) PLoS Pathog , vol.7
    • Yang, J.1    Wang, L.2    Ji, X.3    Feng, Y.4    Li, X.5
  • 22
    • 78149463763 scopus 로고    scopus 로고
    • Regulation of subtilisin-like protease prC expression by nematode cuticle in the nematophagous fungus Clonostachys rosea
    • Zou CG, Tao N, Liu WJ, Yang JK, Huang XW, et al. (2010) Regulation of subtilisin-like protease prC expression by nematode cuticle in the nematophagous fungus Clonostachys rosea. Environ Microbiol 12: 3243-3252.
    • (2010) Environ Microbiol , vol.12 , pp. 3243-3252
    • Zou, C.G.1    Tao, N.2    Liu, W.J.3    Yang, J.K.4    Huang, X.W.5
  • 23
    • 79955934878 scopus 로고    scopus 로고
    • A comprehensive analysis of gene expression changes provoked by bacterial and fungal infection in C. elegans
    • Engelmann I, Griffon A, Tichit L, Montanana-Sanchis F, Wang G, et al. (2011) A comprehensive analysis of gene expression changes provoked by bacterial and fungal infection in C. elegans. PLoS One 6: e19055.
    • (2011) PLoS One , vol.6
    • Engelmann, I.1    Griffon, A.2    Tichit, L.3    Montanana-Sanchis, F.4    Wang, G.5
  • 24
    • 64649085452 scopus 로고    scopus 로고
    • Antifungal innate immunity in C. elegans: PKCdelta links G protein signaling and a conserved p38 MAPK cascade
    • Ziegler K, Kurz CL, Cypowyj S, Couillault C, Pophillat M, et al. (2009) Antifungal innate immunity in C. elegans: PKCdelta links G protein signaling and a conserved p38 MAPK cascade. Cell Host Microbe 5: 341-352.
    • (2009) Cell Host Microbe , vol.5 , pp. 341-352
    • Ziegler, K.1    Kurz, C.L.2    Cypowyj, S.3    Couillault, C.4    Pophillat, M.5
  • 25
    • 34250878419 scopus 로고    scopus 로고
    • Coprinus comatus damages nematode cuticles mechanically with spiny balls and produces potent toxins to immobilize nematodes
    • Luo H, Liu Y, Fang L, Li X, Tang N, et al. (2007) Coprinus comatus damages nematode cuticles mechanically with spiny balls and produces potent toxins to immobilize nematodes. Appl Environ Microbiol 73: 3916-3923.
    • (2007) Appl Environ Microbiol , vol.73 , pp. 3916-3923
    • Luo, H.1    Liu, Y.2    Fang, L.3    Li, X.4    Tang, N.5
  • 26
    • 77956384716 scopus 로고    scopus 로고
    • Systemic and cell intrinsic roles of Gqalpha signaling in the regulation of innate immunity, oxidative stress, and longevity in Caenorhabditis elegans
    • Kawli T, Wu C, Tan MW, (2010) Systemic and cell intrinsic roles of Gqalpha signaling in the regulation of innate immunity, oxidative stress, and longevity in Caenorhabditis elegans. Proc Natl Acad Sci U S A 107: 13788-13793.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 13788-13793
    • Kawli, T.1    Wu, C.2    Tan, M.W.3
  • 27
    • 33751116842 scopus 로고    scopus 로고
    • Insulin-like signaling and the neural circuit for integrative behavior in C. elegans
    • Kodama E, Kuhara A, Mohri-Shiomi A, Kimura KD, Okumura M, et al. (2006) Insulin-like signaling and the neural circuit for integrative behavior in C. elegans. Genes Dev 20: 2955-2960.
    • (2006) Genes Dev , vol.20 , pp. 2955-2960
    • Kodama, E.1    Kuhara, A.2    Mohri-Shiomi, A.3    Kimura, K.D.4    Okumura, M.5
  • 28
    • 0035868890 scopus 로고    scopus 로고
    • Regulation of DAF-2 receptor signaling by human insulin and ins-1, a member of the unusually large and diverse C. elegans insulin gene family
    • Pierce SB, Costa M, Wisotzkey R, Devadhar S, Homburger SA, et al. (2001) Regulation of DAF-2 receptor signaling by human insulin and ins-1, a member of the unusually large and diverse C. elegans insulin gene family. Genes Dev 15: 672-686.
    • (2001) Genes Dev , vol.15 , pp. 672-686
    • Pierce, S.B.1    Costa, M.2    Wisotzkey, R.3    Devadhar, S.4    Homburger, S.A.5
  • 29
    • 82955237578 scopus 로고    scopus 로고
    • A Galphaq-Ca(2) signaling pathway promotes actin-mediated epidermal wound closure in C. elegans
    • Xu S, Chisholm AD, (2011) A Galphaq-Ca(2) signaling pathway promotes actin-mediated epidermal wound closure in C. elegans. Curr Biol 21: 1960-1967.
    • (2011) Curr Biol , vol.21 , pp. 1960-1967
    • Xu, S.1    Chisholm, A.D.2
  • 30
    • 58049214861 scopus 로고    scopus 로고
    • Mechanical induction of an epithelial cell chymase associated with wound edge migration
    • Firth JD, Uitto VJ, Putnins EE, (2008) Mechanical induction of an epithelial cell chymase associated with wound edge migration. J Biol Chem 283: 34983-34993.
    • (2008) J Biol Chem , vol.283 , pp. 34983-34993
    • Firth, J.D.1    Uitto, V.J.2    Putnins, E.E.3
  • 31
    • 67649255876 scopus 로고    scopus 로고
    • A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish
    • Niethammer P, Grabher C, Look AT, Mitchison TJ, (2009) A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish. Nature 459: 996-999.
    • (2009) Nature , vol.459 , pp. 996-999
    • Niethammer, P.1    Grabher, C.2    Look, A.T.3    Mitchison, T.J.4
  • 32
    • 84875229002 scopus 로고    scopus 로고
    • Calcium flashes orchestrate the wound inflammatory response through DUOX activation and hydrogen peroxide release
    • Razzell W, Evans IR, Martin P, Wood W, (2013) Calcium flashes orchestrate the wound inflammatory response through DUOX activation and hydrogen peroxide release. Curr Biol 23: 424-429.
    • (2013) Curr Biol , vol.23 , pp. 424-429
    • Razzell, W.1    Evans, I.R.2    Martin, P.3    Wood, W.4
  • 33
    • 18844382368 scopus 로고    scopus 로고
    • Functional interaction between beta-catenin and FOXO in oxidative stress signaling
    • Essers MA, de Vries-Smits LM, Barker N, Polderman PE, Burgering BM, et al. (2005) Functional interaction between beta-catenin and FOXO in oxidative stress signaling. Science 308: 1181-1184.
    • (2005) Science , vol.308 , pp. 1181-1184
    • Essers, M.A.1    de Vries-Smits, L.M.2    Barker, N.3    Polderman, P.E.4    Burgering, B.M.5
  • 34
    • 0642303115 scopus 로고    scopus 로고
    • Expression of the small heat-shock protein Hsp16-2 in Caenorhabditis elegans is suppressed by Ginkgo biloba extract EGb 761
    • Strayer A, Wu Z, Christen Y, Link CD, Luo Y, (2003) Expression of the small heat-shock protein Hsp16-2 in Caenorhabditis elegans is suppressed by Ginkgo biloba extract EGb 761. FASEB J 17: 2305-2307.
    • (2003) FASEB J , vol.17 , pp. 2305-2307
    • Strayer, A.1    Wu, Z.2    Christen, Y.3    Link, C.D.4    Luo, Y.5
  • 35
    • 33845613251 scopus 로고    scopus 로고
    • Amyloid-beta-induced pathological behaviors are suppressed by Ginkgo biloba extract EGb 761 and ginkgolides in transgenic Caenorhabditis elegans
    • Wu Y, Wu Z, Butko P, Christen Y, Lambert MP, et al. (2006) Amyloid-beta-induced pathological behaviors are suppressed by Ginkgo biloba extract EGb 761 and ginkgolides in transgenic Caenorhabditis elegans. J Neurosci 26: 13102-13113.
    • (2006) J Neurosci , vol.26 , pp. 13102-13113
    • Wu, Y.1    Wu, Z.2    Butko, P.3    Christen, Y.4    Lambert, M.P.5
  • 36
    • 84860803581 scopus 로고    scopus 로고
    • Midlife gene expressions identify modulators of aging through dietary interventions
    • Zhou B, Yang L, Li S, Huang J, Chen H, et al. Midlife gene expressions identify modulators of aging through dietary interventions. Proc Natl Acad Sci U S A 109: E1201-1209.
    • Proc Natl Acad Sci U S A , vol.109
    • Zhou, B.1    Yang, L.2    Li, S.3    Huang, J.4    Chen, H.5
  • 37
    • 77957363643 scopus 로고    scopus 로고
    • Extracellular dopamine potentiates mn-induced oxidative stress, lifespan reduction, and dopaminergic neurodegeneration in a BLI-3-dependent manner in Caenorhabditis elegans
    • Benedetto A, Au C, Avila DS, Milatovic D, Aschner M, (2010) Extracellular dopamine potentiates mn-induced oxidative stress, lifespan reduction, and dopaminergic neurodegeneration in a BLI-3-dependent manner in Caenorhabditis elegans. PLoS Genet 6: e1001084.
    • (2010) PLoS Genet , vol.6
    • Benedetto, A.1    Au, C.2    Avila, D.S.3    Milatovic, D.4    Aschner, M.5
  • 38
    • 0035921417 scopus 로고    scopus 로고
    • Tyrosine cross-linking of extracellular matrix is catalyzed by Duox, a multidomain oxidase/peroxidase with homology to the phagocyte oxidase subunit gp91phox
    • Edens WA, Sharling L, Cheng G, Shapira R, Kinkade JM, et al. (2001) Tyrosine cross-linking of extracellular matrix is catalyzed by Duox, a multidomain oxidase/peroxidase with homology to the phagocyte oxidase subunit gp91phox. J Cell Biol 154: 879-891.
    • (2001) J Cell Biol , vol.154 , pp. 879-891
    • Edens, W.A.1    Sharling, L.2    Cheng, G.3    Shapira, R.4    Kinkade, J.M.5
  • 39
    • 70350439116 scopus 로고    scopus 로고
    • Ce-Duox1/BLI-3 generates reactive oxygen species as a protective innate immune mechanism in Caenorhabditis elegans
    • Chavez V, Mohri-Shiomi A, Garsin DA, (2009) Ce-Duox1/BLI-3 generates reactive oxygen species as a protective innate immune mechanism in Caenorhabditis elegans. Infect Immun 77: 4983-4989.
    • (2009) Infect Immun , vol.77 , pp. 4983-4989
    • Chavez, V.1    Mohri-Shiomi, A.2    Garsin, D.A.3
  • 40
    • 0034927336 scopus 로고    scopus 로고
    • Regulation of phosphoinositide-specific phospholipase C
    • Rhee SG, (2001) Regulation of phosphoinositide-specific phospholipase C. Annu Rev Biochem 70: 281-312.
    • (2001) Annu Rev Biochem , vol.70 , pp. 281-312
    • Rhee, S.G.1
  • 41
    • 3042845373 scopus 로고    scopus 로고
    • IRI-1, a LIN-15B homologue, interacts with inositol-1,4,5-triphosphate receptors and regulates gonadogenesis, defecation, and pharyngeal pumping in Caenorhabditis elegans
    • Walker DS, Ly S, Gower NJ, Baylis HA, (2004) IRI-1, a LIN-15B homologue, interacts with inositol-1,4,5-triphosphate receptors and regulates gonadogenesis, defecation, and pharyngeal pumping in Caenorhabditis elegans. Mol Biol Cell 15: 3073-3082.
    • (2004) Mol Biol Cell , vol.15 , pp. 3073-3082
    • Walker, D.S.1    Ly, S.2    Gower, N.J.3    Baylis, H.A.4
  • 42
    • 0346731274 scopus 로고    scopus 로고
    • Caenorhabditis elegans Galphaq regulates egg-laying behavior via a PLCbeta-independent and serotonin-dependent signaling pathway and likely functions both in the nervous system and in muscle
    • Bastiani CA, Gharib S, Simon MI, Sternberg PW, (2003) Caenorhabditis elegans Galphaq regulates egg-laying behavior via a PLCbeta-independent and serotonin-dependent signaling pathway and likely functions both in the nervous system and in muscle. Genetics 165: 1805-1822.
    • (2003) Genetics , vol.165 , pp. 1805-1822
    • Bastiani, C.A.1    Gharib, S.2    Simon, M.I.3    Sternberg, P.W.4
  • 43
    • 33749510881 scopus 로고    scopus 로고
    • Starvation induces cAMP response element-binding protein-dependent gene expression through octopamine-Gq signaling in Caenorhabditis elegans
    • Suo S, Kimura Y, Van Tol HH, (2006) Starvation induces cAMP response element-binding protein-dependent gene expression through octopamine-Gq signaling in Caenorhabditis elegans. J Neurosci 26: 10082-10090.
    • (2006) J Neurosci , vol.26 , pp. 10082-10090
    • Suo, S.1    Kimura, Y.2    Van Tol, H.H.3
  • 44
    • 33646934067 scopus 로고    scopus 로고
    • A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span
    • Lehtinen MK, Yuan Z, Boag PR, Yang Y, Villen J, et al. (2006) A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span. Cell 125: 987-1001.
    • (2006) Cell , vol.125 , pp. 987-1001
    • Lehtinen, M.K.1    Yuan, Z.2    Boag, P.R.3    Yang, Y.4    Villen, J.5
  • 45
    • 56249116997 scopus 로고    scopus 로고
    • Role for beta-catenin and HOX transcription factors in Caenorhabditis elegans and mammalian host epithelial-pathogen interactions
    • Irazoqui JE, Ng A, Xavier RJ, Ausubel FM, (2008) Role for beta-catenin and HOX transcription factors in Caenorhabditis elegans and mammalian host epithelial-pathogen interactions. Proc Natl Acad Sci U S A 105: 17469-17474.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 17469-17474
    • Irazoqui, J.E.1    Ng, A.2    Xavier, R.J.3    Ausubel, F.M.4
  • 46
    • 84873410016 scopus 로고    scopus 로고
    • Amputation-induced reactive oxygen species are required for successful Xenopus tadpole tail regeneration
    • Love NR, Chen Y, Ishibashi S, Kritsiligkou P, Lea R, et al. (2013) Amputation-induced reactive oxygen species are required for successful Xenopus tadpole tail regeneration. Nat Cell Biol 15: 222-228.
    • (2013) Nat Cell Biol , vol.15 , pp. 222-228
    • Love, N.R.1    Chen, Y.2    Ishibashi, S.3    Kritsiligkou, P.4    Lea, R.5
  • 47
    • 84855263820 scopus 로고    scopus 로고
    • Ce-Duox1/BLI-3 generated reactive oxygen species trigger protective SKN-1 activity via p38 MAPK signaling during infection in C. elegans
    • Hoeven R, McCallum KC, Cruz MR, Garsin DA, (2011) Ce-Duox1/BLI-3 generated reactive oxygen species trigger protective SKN-1 activity via p38 MAPK signaling during infection in C. elegans. PLoS Pathog 7: e1002453.
    • (2011) PLoS Pathog , vol.7
    • Hoeven, R.1    McCallum, K.C.2    Cruz, M.R.3    Garsin, D.A.4
  • 48
    • 34547124879 scopus 로고    scopus 로고
    • Oxidative stress enzymes are required for DAF-16-mediated immunity due to generation of reactive oxygen species by Caenorhabditis elegans
    • Chavez V, Mohri-Shiomi A, Maadani A, Vega LA, Garsin DA, (2007) Oxidative stress enzymes are required for DAF-16-mediated immunity due to generation of reactive oxygen species by Caenorhabditis elegans. Genetics 176: 1567-1577.
    • (2007) Genetics , vol.176 , pp. 1567-1577
    • Chavez, V.1    Mohri-Shiomi, A.2    Maadani, A.3    Vega, L.A.4    Garsin, D.A.5
  • 49
    • 27644498442 scopus 로고    scopus 로고
    • A direct role for dual oxidase in Drosophila gut immunity
    • Ha EM, Oh CT, Bae YS, Lee WJ, (2005) A direct role for dual oxidase in Drosophila gut immunity. Science 310: 847-850.
    • (2005) Science , vol.310 , pp. 847-850
    • Ha, E.M.1    Oh, C.T.2    Bae, Y.S.3    Lee, W.J.4
  • 50
    • 61749104447 scopus 로고    scopus 로고
    • Regulation of DUOX by the Galphaq-phospholipase Cbeta-Ca2+ pathway in Drosophila gut immunity
    • Ha EM, Lee KA, Park SH, Kim SH, Nam HJ, et al. (2009) Regulation of DUOX by the Galphaq-phospholipase Cbeta-Ca2+ pathway in Drosophila gut immunity. Dev Cell 16: 386-397.
    • (2009) Dev Cell , vol.16 , pp. 386-397
    • Ha, E.M.1    Lee, K.A.2    Park, S.H.3    Kim, S.H.4    Nam, H.J.5
  • 51
    • 13944269223 scopus 로고    scopus 로고
    • The plasticity of aging: insights from long-lived mutants
    • Kenyon C, (2005) The plasticity of aging: insights from long-lived mutants. Cell 120: 449-460.
    • (2005) Cell , vol.120 , pp. 449-460
    • Kenyon, C.1
  • 52
    • 2942726155 scopus 로고    scopus 로고
    • The ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation
    • Van Der Heide LP, Hoekman MF, Smidt MP, (2004) The ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation. Biochem J 380: 297-309.
    • (2004) Biochem J , vol.380 , pp. 297-309
    • Van Der Heide, L.P.1    Hoekman, M.F.2    Smidt, M.P.3
  • 53
    • 0030934532 scopus 로고    scopus 로고
    • Wound healing-aiming for perfect skin regeneration
    • Martin P, (1997) Wound healing-aiming for perfect skin regeneration. Science 276: 75-81.
    • (1997) Science , vol.276 , pp. 75-81
    • Martin, P.1
  • 54
    • 19344365657 scopus 로고    scopus 로고
    • Cellular and genetic analysis of wound healing in Drosophila larvae
    • Galko MJ, Krasnow MA, (2004) Cellular and genetic analysis of wound healing in Drosophila larvae. PLoS Biol 2: E239.
    • (2004) PLoS Biol , vol.2
    • Galko, M.J.1    Krasnow, M.A.2
  • 55
    • 17244367891 scopus 로고    scopus 로고
    • An epidermal barrier wound repair pathway in Drosophila is mediated by grainy head
    • Mace KA, Pearson JC, McGinnis W, (2005) An epidermal barrier wound repair pathway in Drosophila is mediated by grainy head. Science 308: 381-385.
    • (2005) Science , vol.308 , pp. 381-385
    • Mace, K.A.1    Pearson, J.C.2    McGinnis, W.3
  • 56
    • 57449104896 scopus 로고    scopus 로고
    • Review series on helminths, immune modulation and the hygiene hypothesis: immunity against helminths and immunological phenomena in modern human populations: coevolutionary legacies?
    • Jackson JA, Friberg IM, Little S, Bradley JE, (2009) Review series on helminths, immune modulation and the hygiene hypothesis: immunity against helminths and immunological phenomena in modern human populations: coevolutionary legacies? Immunology 126: 18-27.
    • (2009) Immunology , vol.126 , pp. 18-27
    • Jackson, J.A.1    Friberg, I.M.2    Little, S.3    Bradley, J.E.4
  • 57
    • 33748094122 scopus 로고    scopus 로고
    • Antimicrobial peptides: an essential component of the skin defensive barrier
    • Braff MH, Gallo RL, (2006) Antimicrobial peptides: an essential component of the skin defensive barrier. Curr Top Microbiol Immunol 306: 91-110.
    • (2006) Curr Top Microbiol Immunol , vol.306 , pp. 91-110
    • Braff, M.H.1    Gallo, R.L.2
  • 58
    • 70350441472 scopus 로고    scopus 로고
    • Multifunctional host defense peptides: antimicrobial peptides, the small yet big players in innate and adaptive immunity
    • Auvynet C, Rosenstein Y, (2009) Multifunctional host defense peptides: antimicrobial peptides, the small yet big players in innate and adaptive immunity. FEBS J 276: 6497-6508.
    • (2009) FEBS J , vol.276 , pp. 6497-6508
    • Auvynet, C.1    Rosenstein, Y.2
  • 59
    • 34447531029 scopus 로고    scopus 로고
    • Transcriptional signature of epidermal keratinocytes subjected to in vitro scratch wounding reveals selective roles for ERK1/2, p38, and phosphatidylinositol 3-kinase signaling pathways
    • Fitsialos G, Chassot AA, Turchi L, Dayem MA, LeBrigand K, et al. (2007) Transcriptional signature of epidermal keratinocytes subjected to in vitro scratch wounding reveals selective roles for ERK1/2, p38, and phosphatidylinositol 3-kinase signaling pathways. J Biol Chem 282: 15090-15102.
    • (2007) J Biol Chem , vol.282 , pp. 15090-15102
    • Fitsialos, G.1    Chassot, A.A.2    Turchi, L.3    Dayem, M.A.4    LeBrigand, K.5
  • 60
    • 77954856727 scopus 로고    scopus 로고
    • Gene expression demonstrates increased resilience toward harmful inflammatory stimuli in the proliferating epidermis of human skin wounds
    • Roupe KM, Alberius P, Schmidtchen A, Sorensen OE, (2010) Gene expression demonstrates increased resilience toward harmful inflammatory stimuli in the proliferating epidermis of human skin wounds. Exp Dermatol 19: e329-332.
    • (2010) Exp Dermatol , vol.19
    • Roupe, K.M.1    Alberius, P.2    Schmidtchen, A.3    Sorensen, O.E.4
  • 61
    • 0016063911 scopus 로고
    • The genetics of Caenorhabditis elegans
    • Brenner S, (1974) The genetics of Caenorhabditis elegans. Genetics 77: 71-94.
    • (1974) Genetics , vol.77 , pp. 71-94
    • Brenner, S.1
  • 62
    • 0038725897 scopus 로고    scopus 로고
    • Genome-wide RNAi screening in Caenorhabditis elegans
    • Kamath RS, Ahringer J, (2003) Genome-wide RNAi screening in Caenorhabditis elegans. Methods 30: 313-321.
    • (2003) Methods , vol.30 , pp. 313-321
    • Kamath, R.S.1    Ahringer, J.2
  • 63
    • 15444371989 scopus 로고    scopus 로고
    • JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16
    • Oh SW, Mukhopadhyay A, Svrzikapa N, Jiang F, Davis RJ, et al. (2005) JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16. Proc Natl Acad Sci U S A 102: 4494-4499.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 4494-4499
    • Oh, S.W.1    Mukhopadhyay, A.2    Svrzikapa, N.3    Jiang, F.4    Davis, R.J.5


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