A Gαq-Ca2+ signaling pathway promotes actin-mediated epidermal wound closure in C. elegans

Current Biology

Volumn 21, Issue 23, 2011, Pages 1960-1967

  Xu, Suhong ^a   Chisholm, Andrew D ^a  

^a SECTION OF CELL AND DEVELOPMENTAL BIOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS REGULATORY PROTEIN; CAENORHABDITIS ELEGANS PROTEIN; CALCIUM; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; DEATH ASSOCIATED PROTEIN KINASE; DEATH-ASSOCIATED PROTEIN KINASE; EGL 30 PROTEIN, C ELEGANS; EGL 8 PROTEIN, C ELEGANS; EGL-30 PROTEIN, C ELEGANS; EGL-8 PROTEIN, C ELEGANS; GTL 2 PROTEIN, C ELEGANS; GTL-2 PROTEIN, C ELEGANS; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; PHOSPHOLIPASE C BETA; TRANSIENT RECEPTOR POTENTIAL CHANNEL M;

ANIMAL; ARTICLE; CAENORHABDITIS ELEGANS; EPIDERMIS; IMMUNOLOGY; INJURY; METABOLISM; NONPARAMETRIC TEST; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SURVIVAL; WOUND HEALING;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CALCIUM; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASES; EPIDERMIS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; PHOSPHOLIPASE C BETA; RNA INTERFERENCE; SIGNAL TRANSDUCTION; STATISTICS, NONPARAMETRIC; SURVIVAL ANALYSIS; TRPM CATION CHANNELS; WOUND HEALING;

ANIMALIA; CAENORHABDITIS ELEGANS;

EID: 82955237578     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2011.10.050     Document Type: Article

References (45)

1. G.C. Gurtner, S. Werner, Y. Barrandon, and M.T. Longaker Wound repair and regeneration Nature 453 2008 314 321 (Pubitemid 351693137)
2. C.K. Sen, G.M. Gordillo, S. Roy, R. Kirsner, L. Lambert, T.K. Hunt, F. Gottrup, G.C. Gurtner, and M.T. Longaker Human skin wounds: a major and snowballing threat to public health and the economy Wound Repair Regen. 17 2009 763 771
3. P. Martin Wound healing - aiming for perfect skin regeneration Science 276 1997 75 81 (Pubitemid 27161246)
4. M. Schäfer, and S. Werner Transcriptional control of wound repair Annu. Rev. Cell Dev. Biol. 23 2007 69 92
5. M.J. Galko, and M.A. Krasnow Cellular and genetic analysis of wound healing in Drosophila larvae PLoS Biol. 2 2004 E239
6. K.A. Mace, J.C. Pearson, and W. McGinnis An epidermal barrier wound repair pathway in Drosophila is mediated by grainy head Science 308 2005 381 385 (Pubitemid 40530069)
7. S.B. Ting, J. Caddy, N. Hislop, T. Wilanowski, A. Auden, L.L. Zhao, S. Ellis, P. Kaur, Y. Uchida, and W.M. Holleran A homolog of Drosophila grainy head is essential for epidermal integrity in mice Science 308 2005 411 413 (Pubitemid 40530078)
8. S. Wang, V. Tsarouhas, N. Xylourgidis, N. Sabri, K. Tiklová, N. Nautiyal, M. Gallio, and C. Samakovlis The tyrosine kinase Stitcher activates Grainy head and epidermal wound healing in Drosophila Nat. Cell Biol. 11 2009 890 895
9. Y. Wu, A.R. Brock, Y. Wang, K. Fujitani, R. Ueda, and M.J. Galko A blood-borne PDGF/VEGF-like ligand initiates wound-induced epidermal cell migration in Drosophila larvae Curr. Biol. 19 2009 1473 1477
10. S. Werner, and R. Grose Regulation of wound healing by growth factors and cytokines Physiol. Rev. 83 2003 835 870 (Pubitemid 36828927)
11. H. Luo, Y. Liu, L. Fang, X. Li, N. Tang, and K. Zhang Coprinus comatus damages nematode cuticles mechanically with spiny balls and produces potent toxins to immobilize nematodes Appl. Environ. Microbiol. 73 2007 3916 3923 (Pubitemid 46983238)
12. S.L. Glockling, and G.W. Beakes An ultrastructural study of sporidium formation during infection of a rhabditid nematode by large gun cells of Haptoglossa heteromorpha J. Invertebr. Pathol. 76 2000 208 215
13. N. Pujol, S. Cypowyj, K. Ziegler, A. Millet, A. Astrain, A. Goncharov, Y. Jin, A.D. Chisholm, and J.J. Ewbank Distinct innate immune responses to infection and wounding in the C. elegans epidermis Curr. Biol. 18 2008 481 489
14. A. Tong, G. Lynn, V. Ngo, D. Wong, S.L. Moseley, J.J. Ewbank, A. Goncharov, Y.C. Wu, N. Pujol, and A.D. Chisholm Negative regulation of Caenorhabditis elegans epidermal damage responses by death-associated protein kinase Proc. Natl. Acad. Sci. USA 106 2009 1457 1461
15. M. Stanisstreet Calcium and wound healing in Xenopus early embryos J. Embryol. Exp. Morphol. 67 1982 195 205 (Pubitemid 12177050)
16. P.L. McNeil, and R.A. Steinhardt Plasma membrane disruption: repair, prevention, adaptation Annu. Rev. Cell Dev. Biol. 19 2003 697 731 (Pubitemid 37487366)
17. S. Nodder, and P. Martin Wound healing in embryos: a review Anat. Embryol. (Berl.) 195 1997 215 228 (Pubitemid 27116444)
18. L. Tian, S.A. Hires, T. Mao, D. Huber, M.E. Chiappe, S.H. Chalasani, L. Petreanu, J. Akerboom, S.A. McKinney, and E.R. Schreiter Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators Nat. Methods 6 2009 875 881
19. D.S. Walker, N.J. Gower, S. Ly, G.L. Bradley, and H.A. Baylis Regulated disruption of inositol 1,4,5-trisphosphate signaling in Caenorhabditis elegans reveals new functions in feeding and embryogenesis Mol. Biol. Cell 13 2002 1329 1337 (Pubitemid 34309626)
20. A.H. Kahn-Kirby, and C.I. Bargmann TRP channels in C. elegans Annu. Rev. Physiol. 68 2006 719 736
21. T.M. Stawicki, K. Zhou, J. Yochem, L. Chen, and Y. Jin TRPM channels modulate epileptic-like convulsions via systemic ion homeostasis Curr. Biol. 21 2011 883 888
22. T. Teramoto, L.A. Sternick, E. Kage-Nakadai, S. Sajjadi, J. Siembida, S. Mitani, K. Iwasaki, and E.J. Lambie Magnesium excretion in C. elegans requires the activity of the GTL-2 TRPM channel PLoS ONE 5 2010 e9589
23. C. Couillault, N. Pujol, J. Reboul, L. Sabatier, J.F. Guichou, Y. Kohara, and J.J. Ewbank TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM Nat. Immunol. 5 2004 488 494 (Pubitemid 38660460)
24. C.A. Bastiani, S. Gharib, M.I. Simon, and P.W. Sternberg Caenorhabditis elegans Galphaq regulates egg-laying behavior via a PLCβ-independent and serotonin-dependent signaling pathway and likely functions both in the nervous system and in muscle Genetics 165 2003 1805 1822 (Pubitemid 38040271)
25. O. Zugasti, and J.J. Ewbank Neuroimmune regulation of antimicrobial peptide expression by a noncanonical TGF-β signaling pathway in Caenorhabditis elegans epidermis Nat. Immunol. 10 2009 249 256
26. K. Ziegler, C.L. Kurz, S. Cypowyj, C. Couillault, M. Pophillat, N. Pujol, and J.J. Ewbank Antifungal innate immunity in C. elegans: PKCδ links G protein signaling and a conserved p38 MAPK cascade Cell Host Microbe 5 2009 341 352
27. P. Martin, and J. Lewis Actin cables and epidermal movement in embryonic wound healing Nature 360 1992 179 183
28. W. Wood, A. Jacinto, R. Grose, S. Woolner, J. Gale, C. Wilson, and P. Martin Wound healing recapitulates morphogenesis in Drosophila embryos Nat. Cell Biol. 4 2002 907 912 (Pubitemid 35331367)
29. C. Lesch, J. Jo, Y. Wu, G.S. Fish, and M.J. Galko A targeted UAS-RNAi screen in Drosophila larvae identifies wound closure genes regulating distinct cellular processes Genetics 186 2010 943 957
30. A.G. Clark, A.L. Miller, E. Vaughan, H.Y. Yu, R. Penkert, and W.M. Bement Integration of single and multicellular wound responses Curr. Biol. 19 2009 1389 1395
31. K.A. Edwards, M. Demsky, R.A. Montague, N. Weymouth, and D.P. Kiehart GFP-moesin illuminates actin cytoskeleton dynamics in living tissue and demonstrates cell shape changes during morphogenesis in Drosophila Dev. Biol. 191 1997 103 117 (Pubitemid 27519708)
32. J. Brock, K. Midwinter, J. Lewis, and P. Martin Healing of incisional wounds in the embryonic chick wing bud: characterization of the actin purse-string and demonstration of a requirement for Rho activation J. Cell Biol. 135 1996 1097 1107 (Pubitemid 26403781)
33. C.D. Nobes, and A. Hall Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia Cell 81 1995 53 62
34. A.J. Piekny, J.L. Johnson, G.D. Cham, and P.E. Mains The Caenorhabditis elegans nonmuscle myosin genes nmy-1 and nmy-2 function as redundant components of the let-502/Rho-binding kinase and mel-11/myosin phosphatase pathway during embryonic morphogenesis Development 130 2003 5695 5704 (Pubitemid 37540844)
35. S. Bialik, A.R. Bresnick, and A. Kimchi DAP-kinase-mediated morphological changes are localization dependent and involve myosin-II phosphorylation Cell Death Differ. 11 2004 631 644 (Pubitemid 38786711)
36. T. Kawli, C. Wu, and M.W. Tan Systemic and cell intrinsic roles of Gqα signaling in the regulation of innate immunity, oxidative stress, and longevity in Caenorhabditis elegans Proc. Natl. Acad. Sci. USA 107 2010 13788 13793
37. A.P. Christensen, and D.P. Corey TRP channels in mechanosensation: direct or indirect activation? Nat. Rev. Neurosci. 8 2007 510 521 (Pubitemid 46985360)
38. T. Yamada, T. Ueda, S. Ugawa, Y. Ishida, M. Imayasu, S. Koyama, and S. Shimada Functional expression of transient receptor potential vanilloid 3 (TRPV3) in corneal epithelial cells: involvement in thermosensation and wound healing Exp. Eye Res. 90 2010 121 129
39. M. Denda, M. Tsutsumi, and S. Denda Topical application of TRPM8 agonists accelerates skin permeability barrier recovery and reduces epidermal proliferation induced by barrier insult: role of cold-sensitive TRP receptors in epidermal permeability barrier homoeostasis Exp. Dermatol. 19 2010 791 795
40. H.A. Benink, and W.M. Bement Concentric zones of active RhoA and Cdc42 around single cell wounds J. Cell Biol. 168 2005 429 439 (Pubitemid 40205065)
41. W.M. Bement, H.Y. Yu, B.M. Burkel, E.M. Vaughan, and A.G. Clark Rehabilitation and the single cell Curr. Opin. Cell Biol. 19 2007 95 100 (Pubitemid 46123967)
42. E.M. Vaughan, A.L. Miller, H.Y. Yu, and W.M. Bement Control of local Rho GTPase crosstalk by Abr Curr. Biol. 21 2011 270 277
43. K.J. Sonnemann, and W.M. Bement Wound repair: toward understanding and integration of single-cell and multicellular wound responses Annu. Rev. Cell Dev. Biol. 27 2011 237 263
44. S. Bialik, and A. Kimchi The death-associated protein kinases: structure, function, and beyond Annu. Rev. Biochem. 75 2006 189 210 (Pubitemid 44118031)
45. A. Ghosh-Roy, Z. Wu, A. Goncharov, Y. Jin, and A.D. Chisholm Calcium and cyclic AMP promote axonal regeneration in Caenorhabditis elegans and require DLK-1 kinase J. Neurosci. 30 2010 3175 3183