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Volumn , Issue , 2013, Pages 67-101

Drug Solubilization and Stabilization by Cyclodextrin Drug Carriers

Author keywords

Complexation; Complexation efficiency; Cyclodextrin; Cyclodextrin drug stabilization; Cyclodextrin monograph; Permeation; Pharmacokinetics; Phase solubility diagram; Stability constant; Toxicity

Indexed keywords


EID: 84887223190     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9781118444726.ch3     Document Type: Chapter
Times cited : (10)

References (178)
  • 1
    • 0001627521 scopus 로고
    • Sur la fermentation de la fécule par l'action du ferment butyrique
    • A. Villiers, Sur la fermentation de la fécule par l'action du ferment butyrique. Compt Rend Acad Sci, 112, 536-538 (1891).
    • (1891) Compt Rend Acad Sci , vol.112 , pp. 536-538
    • Villiers, A.1
  • 2
    • 33845573098 scopus 로고    scopus 로고
    • Cyclodextrins and their pharmaceutical applications
    • T. Loftsson, D. Ducĥene, Cyclodextrins and their pharmaceutical applications. Int J Pharm, 329, 1-11 (2007).
    • (2007) Int J Pharm , vol.329 , pp. 1-11
    • Loftsson, T.1    Ducĥene, D.2
  • 3
    • 34347119026 scopus 로고
    • Über Thermophile Bakterien aus verschiedenen Speisen und Milch, sowie über einige Umsetzungsprodukte derselben in kohlenhydrathältigen Nährlösungen, darunter krystallisierte Polysaccharide (Dextrine) aus Stärke
    • F. Schardinger, Über Thermophile Bakterien aus verschiedenen Speisen und Milch, sowie über einige Umsetzungsprodukte derselben in kohlenhydrathältigen Nährlösungen, darunter krystallisierte Polysaccharide (Dextrine) aus Stärke. Z Untersuch Nahr u Genussm, 6, 865-880 (1903).
    • (1903) Z Untersuch Nahr u Genussm , vol.6 , pp. 865-880
    • Schardinger, F.1
  • 4
    • 77749311064 scopus 로고
    • Über Schardinger Dextrine aus Star̈ke
    • K. Freudenberg, R. Jacobi, Über Schardinger Dextrine aus Star̈ke. Liebigs Ann Chem, 518, 102-108 (1935).
    • (1935) Liebigs Ann Chem , vol.518 , pp. 102-108
    • Freudenberg, K.1    Jacobi, R.2
  • 5
    • 17644398052 scopus 로고
    • Die Konstitution der Schardinger-Dextrine a, b und g
    • K. Freudenberg, F. Cramer, Die Konstitution der Schardinger-Dextrine a, b und g. Z Naturforsch, 3b, 464 (1948).
    • (1948) Z Naturforsch , vol.3 b , pp. 464
    • Freudenberg, K.1    Cramer, F.2
  • 6
    • 0013789908 scopus 로고
    • Studies on the Schardinger dextrins. XII. The molecular size and structure of the d-, e-, z-, and h-dextrins
    • D. French, A.O. Pulley, J.A. Effenberger, M.A. Rougvie, M. Abdullah, Studies on the Schardinger dextrins. XII. The molecular size and structure of the d-, e-, z-, and h-dextrins. Arch Biochem Biophys, 111, 153-160 (1965).
    • (1965) Arch Biochem Biophys , vol.111 , pp. 153-160
    • French, D.1    Pulley, A.O.2    Effenberger, J.A.3    Rougvie, M.A.4    Abdullah, M.5
  • 8
    • 0002647077 scopus 로고    scopus 로고
    • Isolation, purification, and characterization of cyclomaltodecaose
    • in Proceedings of the Eighth International Symposium on Cyclodextrins, Szejtli, J., Szente, L. (eds). Dordrecht: Kluwer Academic Publishers
    • H. Ueda, T. Endo, H. Nagase, S. Kobayashi, T. Nagai, Isolation, purification, and characterization of cyclomaltodecaose. in Proceedings of the Eighth International Symposium on Cyclodextrins, Szejtli, J., Szente, L. (eds). Dordrecht: Kluwer Academic Publishers, pp. 17-20 (1996).
    • (1996) , pp. 17-20
    • Ueda, H.1    Endo, T.2    Nagase, H.3    Kobayashi, S.4    Nagai, T.5
  • 9
    • 84890985120 scopus 로고    scopus 로고
    • Large-ring cyclodextrins
    • in Cyclodextrins and their Complexes: Chemistry, Analytical Methods, Applications, Dodziuk, H. (ed.), Weinheim: Wiley-VCH Verlag
    • H. Ueda, T. Endo, Large-ring cyclodextrins, in Cyclodextrins and their Complexes: Chemistry, Analytical Methods, Applications, Dodziuk, H. (ed.), Weinheim: Wiley-VCH Verlag, pp. 370-380 (2006).
    • (2006) , pp. 370-380
    • Ueda, H.1    Endo, T.2
  • 10
    • 77649134097 scopus 로고
    • Verfahren zur Herstellung von Einschlußverbindungen physiologisch wirksamer organischer Verbindungen
    • Knoll A.-G. Chemische Fabriken
    • K. Freudenberg, F. Cramer, H. Plieninger, Verfahren zur Herstellung von Einschlußverbindungen physiologisch wirksamer organischer Verbindungen. Knoll A.-G. Chemische Fabriken (1953).
    • (1953)
    • Freudenberg, K.1    Cramer, F.2    Plieninger, H.3
  • 11
    • 0004085301 scopus 로고
    • Einschlussverbindungen
    • Berlin: Springer-Verlag
    • F. Cramer, Einschlussverbindungen. Berlin: Springer-Verlag (1954).
    • (1954)
    • Cramer, F.1
  • 12
    • 78649654159 scopus 로고    scopus 로고
    • Pharmaceutical applications of cyclodextrins: Basic science and product development
    • T. Loftsson, M.E. Brewster, Pharmaceutical applications of cyclodextrins: Basic science and product development. J Pharm Pharmacol, 62, 1607-1621 (2010).
    • (2010) J Pharm Pharmacol , vol.62 , pp. 1607-1621
    • Loftsson, T.1    Brewster, M.E.2
  • 13
    • 0033403988 scopus 로고    scopus 로고
    • Some important considerations in the use of cyclodextrins
    • J. Blanchard, S. Proniuk, Some important considerations in the use of cyclodextrins. Pharm Res, 16, 1796-1798 (1999).
    • (1999) Pharm Res , vol.16 , pp. 1796-1798
    • Blanchard, J.1    Proniuk, S.2
  • 14
    • 0004292227 scopus 로고
    • Cyclodextrins in Pharmacy
    • Dordrecht: Kluwer Academic Publishers
    • K.H. Frömming, J. Szejtli, Cyclodextrins in Pharmacy. Dordrecht: Kluwer Academic Publishers (1994).
    • (1994)
    • Frömming, K.H.1    Szejtli, J.2
  • 15
    • 0004063197 scopus 로고
    • Cyclodextrin Technology
    • Dordrecht: Kluwer Academic Publishers
    • J. Szejtli, Cyclodextrin Technology. Dordrecht: Kluwer Academic Publishers (1988).
    • (1988)
    • Szejtli, J.1
  • 16
    • 0027085845 scopus 로고
    • Acid-catalyzed hydrolysis of maltosyl-β-cyclodextrin
    • F. Hirayama, M. Yamamoto, K. Uekama, Acid-catalyzed hydrolysis of maltosyl-β-cyclodextrin. J Pharm Sci, 81, 913-916 (1992).
    • (1992) J Pharm Sci , vol.81 , pp. 913-916
    • Hirayama, F.1    Yamamoto, M.2    Uekama, K.3
  • 17
    • 58149083826 scopus 로고    scopus 로고
    • Structural base for enzymatic cyclodextrin hydrolysis
    • S. Buedenbender, G.E. Schulz, Structural base for enzymatic cyclodextrin hydrolysis. J Mol Biol, 385, 606-617 (2009).
    • (2009) J Mol Biol , vol.385 , pp. 606-617
    • Buedenbender, S.1    Schulz, G.E.2
  • 18
    • 0013614631 scopus 로고
    • The metabolism, toxicity and biological effects of cyclodextrins
    • in Ducĥene, D. (ed.), Cyclodextrins and Their Uses. Paris: Editions de Santé
    • J. Szejtli, The metabolism, toxicity and biological effects of cyclodextrins, in Ducĥene, D. (ed.), Cyclodextrins and Their Uses. Paris: Editions de Santé, pp. 173-212 (1987).
    • (1987) , pp. 173-212
    • Szejtli, J.1
  • 20
    • 0031054513 scopus 로고    scopus 로고
    • Pharmaceutical applications of cyclodextrins. III. Toxicological issues and safety evaluation
    • T. Irie, K. Uekama, Pharmaceutical applications of cyclodextrins. III. Toxicological issues and safety evaluation. J Pharm Sci, 86(2), 147-162 (1997).
    • (1997) J Pharm Sci , vol.86 , Issue.2 , pp. 147-162
    • Irie, T.1    Uekama, K.2
  • 21
    • 41949086127 scopus 로고    scopus 로고
    • Cyclodextrins
    • V.J. Stella, Q. He, Cyclodextrins. Tox Pathol, 36, 30-42 (2008).
    • (2008) Tox Pathol , vol.36 , pp. 30-42
    • Stella, V.J.1    He, Q.2
  • 22
    • 0344537893 scopus 로고    scopus 로고
    • Toxicological comparison of cyclodextrins
    • In Szejtli, J., Szente, L., editors. Proceedings of the Eighth International Symposium on Cyclodextrins. Budapest, Hungary, March 30-April 2, 1996, ed., Dordrecht: Kluwer Academic Publishers
    • G. Antlsperger, G. Schmid, Toxicological comparison of cyclodextrins. In Szejtli, J., Szente, L., editors. Proceedings of the Eighth International Symposium on Cyclodextrins. Budapest, Hungary, March 30-April 2, 1996, ed., Dordrecht: Kluwer Academic Publishers, pp. 149-155 (1996).
    • (1996) , pp. 149-155
    • Antlsperger, G.1    Schmid, G.2
  • 23
    • 4243919329 scopus 로고
    • New aspects in cyclodextrin toxicology
    • In Hedges, A.R. (ed.), Minutes of the Sixth International Symposium on Cyclodextrins, Paris: Editions de Santé
    • G. Antlsperger, New aspects in cyclodextrin toxicology. In Hedges, A.R. (ed.), Minutes of the Sixth International Symposium on Cyclodextrins, Paris: Editions de Santé. pp. 277-283 (1992).
    • (1992) , pp. 277-283
    • Antlsperger, G.1
  • 24
    • 0031594950 scopus 로고    scopus 로고
    • Disposition of 14C-γ-cyclodextrin in germfree and conventional rats
    • A.T.H.J. De Bie, B. van Ommen, A. Bär, Disposition of 14C-γ-cyclodextrin in germfree and conventional rats. Regul Toxicol Pharmacol, 27, 150-158 (1998).
    • (1998) Regul Toxicol Pharmacol , vol.27 , pp. 150-158
    • De Bie, A.T.H.J.1    Van Ommen, B.2    Bär, A.3
  • 25
    • 3242685928 scopus 로고    scopus 로고
    • Disposition of 14C-α-cyclodextrin in germ-free and conventional rats
    • B. Van Ommen, A.T.H.J. De Bie, A. Bär, Disposition of 14C-α-cyclodextrin in germ-free and conventional rats. Regul Toxicol Pharmacol, 39, S57-S66 (2004).
    • (2004) Regul Toxicol Pharmacol , vol.39
    • Van Ommen, B.1    De Bie, A.T.H.J.2    Bär, A.3
  • 26
    • 0031927438 scopus 로고    scopus 로고
    • A pharmacokinetic study of intravenous intraconazole followed by oral administration of intraconazole capsules in patients with advanced human immunodeficiency virus infection
    • H. Zhou, M. Goldman, J. Wu, R. Woestenborghs, A.E. Hassell, P. Lee, A. Baruch, L. Pesco-Koplowitz, J. Borum, L.J. Wheat, A pharmacokinetic study of intravenous intraconazole followed by oral administration of intraconazole capsules in patients with advanced human immunodeficiency virus infection. J Clin Pharmacol, 38, 593-602 (1998).
    • (1998) J Clin Pharmacol , vol.38 , pp. 593-602
    • Zhou, H.1    Goldman, M.2    Wu, J.3    Woestenborghs, R.4    Hassell, A.E.5    Lee, P.6    Baruch, A.7    Pesco-Koplowitz, L.8    Borum, J.9    Wheat, L.J.10
  • 28
    • 0005043708 scopus 로고
    • Alteration of apparent solubility through complexation
    • InYalkowski, S.H. (ed.) Techniques of Solubilization of Drugs. New York: Marcel Dekker
    • A.J. Repta, Alteration of apparent solubility through complexation. InYalkowski, S.H. (ed.) Techniques of Solubilization of Drugs. New York: Marcel Dekker, pp. 135-157 (1985).
    • (1985) , pp. 135-157
    • Repta, A.J.1
  • 29
    • 34548134519 scopus 로고    scopus 로고
    • Cyclodextrins as pharmaceutical solubilizers
    • M.E. Brewster, T. Loftsson, Cyclodextrins as pharmaceutical solubilizers. Adv Drug Deliv Rev, 59, 645-666 (2007).
    • (2007) Adv Drug Deliv Rev , vol.59 , pp. 645-666
    • Brewster, M.E.1    Loftsson, T.2
  • 30
    • 0006385989 scopus 로고    scopus 로고
    • Complexation: Use of cyclodextrins to improve pharmaceutical properties of intramuscular formulations
    • In Gupta, P.K., Brazeau, G.A. (eds), injectable Drug Development Techniques to Reduce Pain and Irritation. Denver: Interpharm Press
    • M.E. Brewster, T. Loftsson, Complexation: Use of cyclodextrins to improve pharmaceutical properties of intramuscular formulations. In Gupta, P.K., Brazeau, G.A. (eds), injectable Drug Development Techniques to Reduce Pain and Irritation. Denver: Interpharm Press, pp. 307-336 (1999).
    • (1999) , pp. 307-336
    • Brewster, M.E.1    Loftsson, T.2
  • 31
    • 33646036370 scopus 로고    scopus 로고
    • Investigation of γ-cyclodextrin nanotube induced by N,N-diphenylbenzidine molecule
    • A. Wu, X. Shen, Y. He, Investigation of γ-cyclodextrin nanotube induced by N,N-diphenylbenzidine molecule. J Coll Interf Sci, 297, 525-533 (2006).
    • (2006) J Coll Interf Sci , vol.297 , pp. 525-533
    • Wu, A.1    Shen, X.2    He, Y.3
  • 32
    • 33747351023 scopus 로고    scopus 로고
    • Micrometer-sized rodlike structure formed by the secondary assembly of cyclodextrin nanotube
    • A. Wu, X. Shen, Y. He, Micrometer-sized rodlike structure formed by the secondary assembly of cyclodextrin nanotube. J Coll Interf Sci, 302, 87-89 (2006).
    • (2006) J Coll Interf Sci , vol.302 , pp. 87-89
    • Wu, A.1    Shen, X.2    He, Y.3
  • 33
    • 33644507141 scopus 로고    scopus 로고
    • Selfassembly of β-cyclodextrin in water. Part 1: Cryo-TEM and dynamic and static light scattering
    • M. Bonini, S. Rossi, G. Karlsson, M. Almgren, P. Lo Nostro, P. Baglioni, Selfassembly of β-cyclodextrin in water. Part 1: Cryo-TEM and dynamic and static light scattering. Langmuir, 22, 1478-1484 (2006).
    • (2006) Langmuir , vol.22 , pp. 1478-1484
    • Bonini, M.1    Rossi, S.2    Karlsson, G.3    Almgren, M.4    Lo Nostro, P.5    Baglioni, P.6
  • 34
    • 74049133227 scopus 로고    scopus 로고
    • Cyclodextrins as solubilizers: formation of complex aggregates
    • P. Jansook, S.V. Kurkov, T. Loftsson, Cyclodextrins as solubilizers: formation of complex aggregates. J Pharm Sci, 99, 719-729 (2010).
    • (2010) J Pharm Sci , vol.99 , pp. 719-729
    • Jansook, P.1    Kurkov, S.V.2    Loftsson, T.3
  • 35
    • 78049300670 scopus 로고    scopus 로고
    • Effect of self-aggregation of γ-cyclodextrin on drug solubilization
    • P. Jansook, M.D. Moya-Ortega, T. Loftsson, Effect of self-aggregation of γ-cyclodextrin on drug solubilization. J Incl Phenom Macroc Chem, 68, 229-236 (2010).
    • (2010) J Incl Phenom Macroc Chem , vol.68 , pp. 229-236
    • Jansook, P.1    Moya-Ortega, M.D.2    Loftsson, T.3
  • 36
    • 77649189513 scopus 로고    scopus 로고
    • Self-assembled cyclodextrin aggregates and nanoparticles
    • M. Messner, S.V.Kurkov, P. Jansook, T. Loftsson, Self-assembled cyclodextrin aggregates and nanoparticles. Int J Pharm, 387, 199-208 (2010).
    • (2010) Int J Pharm , vol.387 , pp. 199-208
    • Messner, M.1    Kurkov, S.V.2    Jansook, P.3    Loftsson, T.4
  • 37
    • 0024413624 scopus 로고
    • Aggregation of amphotericin B in the presence of g-cyclodextrin
    • M. Kajtár, M. Vikmon, E. Morlin, J. Szejtli, Aggregation of amphotericin B in the presence of g-cyclodextrin. Biopolymers, 28, 1585-1596 (1989).
    • (1989) Biopolymers , vol.28 , pp. 1585-1596
    • Kajtár, M.1    Vikmon, M.2    Morlin, E.3    Szejtli, J.4
  • 38
    • 33745048423 scopus 로고
    • Aggregation of cyclodextrins: an explanation of the abnormal solubility of β-cyclodextrin
    • A.W. Coleman, I. Nicolis, N. Keller, J.P. Dalbiez, Aggregation of cyclodextrins: an explanation of the abnormal solubility of β-cyclodextrin. J Incl Phenom Macroc Chem, 13, 139-143 (1992).
    • (1992) J Incl Phenom Macroc Chem , vol.13 , pp. 139-143
    • Coleman, A.W.1    Nicolis, I.2    Keller, N.3    Dalbiez, J.P.4
  • 40
    • 0036674809 scopus 로고    scopus 로고
    • On the specificity of cyclodextrin complexes detected by electrospray mass spectrometry
    • V. Gabelica, N. Galic, E. De Pauw, On the specificity of cyclodextrin complexes detected by electrospray mass spectrometry. J Am Soc Mass Spectrom, 13, 946-953 (2002).
    • (2002) J Am Soc Mass Spectrom , vol.13 , pp. 946-953
    • Gabelica, V.1    Galic, N.2    De Pauw, E.3
  • 41
    • 0036716366 scopus 로고    scopus 로고
    • Study of inclusion complexes of acridine with b-and (2,6-di-O-methyl)-b-cyclodextrin by use of solubility diagrams and NMR spectroscopy
    • I. Correia, N. Bezzenine, N. Ronzani, N. Platzer, J.-C. Beloeil, B.-T. Doan, Study of inclusion complexes of acridine with b-and (2,6-di-O-methyl)-b-cyclodextrin by use of solubility diagrams and NMR spectroscopy. J Phys Org Chem, 15, 647-659 (2002).
    • (2002) J Phys Org Chem , vol.15 , pp. 647-659
    • Correia, I.1    Bezzenine, N.2    Ronzani, N.3    Platzer, N.4    Beloeil, J.-C.5    Doan, B.-T.6
  • 42
    • 1942434694 scopus 로고    scopus 로고
    • Self-association of cyclodextrins and cyclodextrin complexes
    • T. Loftsson, M. Másson, M.E. Brewster, Self-association of cyclodextrins and cyclodextrin complexes. J Pharm Sci, 93, 1091-1099 (2004).
    • (2004) J Pharm Sci , vol.93 , pp. 1091-1099
    • Loftsson, T.1    Másson, M.2    Brewster, M.E.3
  • 43
    • 33845867423 scopus 로고    scopus 로고
    • Aggregation of cyclodextrins as an important factor to determine their complexation behavior
    • Z. Bikádi, R. Kurdi, S. Balogh, J. Szemán, E. Hazai, Aggregation of cyclodextrins as an important factor to determine their complexation behavior. Chem Biodiv, 3, 1266-1276 (2006).
    • (2006) Chem Biodiv , vol.3 , pp. 1266-1276
    • Bikádi, Z.1    Kurdi, R.2    Balogh, S.3    Szemán, J.4    Hazai, E.5
  • 44
    • 34248590946 scopus 로고    scopus 로고
    • Interaction between β-cyclodextrin and mixed cationicanionic surfactants (2): aggregation behavior
    • P.Yan, J.-N. Tang, J.-X. Xiao, Interaction between β-cyclodextrin and mixed cationicanionic surfactants (2): aggregation behavior. J Dispers Sci Technol, 28, 623-626 (2007).
    • (2007) J Dispers Sci Technol , vol.28 , pp. 623-626
    • Yan, P.1    Tang, J.-N.2    Xiao, J.-X.3
  • 45
    • 79952314729 scopus 로고    scopus 로고
    • Self-assembly of cyclodextrin complexes: Aggregation of hydrocortisone/cyclodextrin complexes
    • M. Messner, S.V. Kurkov, M.E. Brewster, P. Jansook, T. Loftsson, Self-assembly of cyclodextrin complexes: Aggregation of hydrocortisone/cyclodextrin complexes. Int. J. Pharm, 407, 174-183 (2011).
    • (2011) Int. J. Pharm , vol.407 , pp. 174-183
    • Messner, M.1    Kurkov, S.V.2    Brewster, M.E.3    Jansook, P.4    Loftsson, T.5
  • 46
    • 84887245639 scopus 로고    scopus 로고
    • Self-assembly of cyclodextrin complexes: The effect of the guest molecule
    • manuscript
    • M. Messner, S.V. Kurkov, R. Flavià-Piera, M.E. Brewster, T. Loftsson, Self-assembly of cyclodextrin complexes: The effect of the guest molecule (manuscript) (2011).
    • (2011)
    • Messner, M.1    Kurkov, S.V.2    Flavià-Piera, R.3    Brewster, M.E.4    Loftsson, T.5
  • 47
    • 24344508654 scopus 로고    scopus 로고
    • Evaluation of cyclodextrin solubilization of drugs
    • T. Loftsson, D. Hreinsdóttir, M. Másson, Evaluation of cyclodextrin solubilization of drugs. Int J Pharm, 302, 18-28 (2005).
    • (2005) Int J Pharm , vol.302 , pp. 18-28
    • Loftsson, T.1    Hreinsdóttir, D.2    Másson, M.3
  • 50
    • 0031808232 scopus 로고    scopus 로고
    • Spontaneous opalescence of aqueous γ-cyclodextrin solutions: complex formation or self-aggregation
    • L. Szente, J. Szejtli, G.L. Kis, Spontaneous opalescence of aqueous γ-cyclodextrin solutions: complex formation or self-aggregation. J Pharm Sci, 87, 778-781 (1998).
    • (1998) J Pharm Sci , vol.87 , pp. 778-781
    • Szente, L.1    Szejtli, J.2    Kis, G.L.3
  • 51
    • 0033106020 scopus 로고    scopus 로고
    • Highly soluble cyclodextrin derivatives: chemistry, properties, and trends in development
    • L. Szente, J. Szejtli, Highly soluble cyclodextrin derivatives: chemistry, properties, and trends in development. Adv Drug Deliv Rev, 36, 17-28 (1999).
    • (1999) Adv Drug Deliv Rev , vol.36 , pp. 17-28
    • Szente, L.1    Szejtli, J.2
  • 53
    • 44849090011 scopus 로고    scopus 로고
    • Cyclodextrin-based aggregates and characterization by microscopy
    • W. He, P. Fu, X.H. Shen, H.C. Gao, Cyclodextrin-based aggregates and characterization by microscopy. Micron, 39, 495-516 (2008).
    • (2008) Micron , vol.39 , pp. 495-516
    • He, W.1    Fu, P.2    Shen, X.H.3    Gao, H.C.4
  • 56
    • 0345765003 scopus 로고    scopus 로고
    • The effects of cyclodextrins on hydrocortisone permeability through semi-permeable membranes
    • H.H. Sigurdsson, A. Magnusdottir, M. Masson, T. Loftsson. The effects of cyclodextrins on hydrocortisone permeability through semi-permeable membranes. J Incl Phenom Macrocycl Chem, 44, 163-167 (2002).
    • (2002) J Incl Phenom Macrocycl Chem , vol.44 , pp. 163-167
    • Sigurdsson, H.H.1    Magnusdottir, A.2    Masson, M.3    Loftsson, T.4
  • 57
    • 0029820373 scopus 로고    scopus 로고
    • Thermodynamics of hydrogen bond and hydrophobic interactions in cyclodextrin complexes
    • P.D. Ross, M.V. Rekharsky, Thermodynamics of hydrogen bond and hydrophobic interactions in cyclodextrin complexes. Biophys J, 71, 2144-2154 (1996).
    • (1996) Biophys J , vol.71 , pp. 2144-2154
    • Ross, P.D.1    Rekharsky, M.V.2
  • 60
    • 0029093982 scopus 로고
    • Thermodynamic and nuclear magnetic resonance study of the interactions of α-and β-cyclodextrin with model substances: phenethylamine, ephedrines, and related substances
    • M.V. Rekharsky, R.N. Goldberg, F.P. Schwarz, Y.B. Tewari, P.D. Ross, Y. Yamashoji, Y. Inoue, Thermodynamic and nuclear magnetic resonance study of the interactions of α-and β-cyclodextrin with model substances: phenethylamine, ephedrines, and related substances. J Am Chem Soc, 145, 8830-8840 (1995).
    • (1995) J Am Chem Soc , vol.145 , pp. 8830-8840
    • Rekharsky, M.V.1    Goldberg, R.N.2    Schwarz, F.P.3    Tewari, Y.B.4    Ross, P.D.5    Yamashoji, Y.6    Inoue, Y.7
  • 62
    • 84985609923 scopus 로고
    • Cyclodextrin inclusion compounds in research and industry
    • W. Saenger, Cyclodextrin inclusion compounds in research and industry. AngewChem Int Ed Engl, 19, 344-362 (1980).
    • (1980) AngewChem Int Ed Engl , vol.19 , pp. 344-362
    • Saenger, W.1
  • 63
    • 0038185084 scopus 로고    scopus 로고
    • The driving forces in the inclusion complexation of cyclodextrins
    • L. Liu, Q.-X. Guo, The driving forces in the inclusion complexation of cyclodextrins. J Incl Phenom Macroc Chem, 42, 1-14 (2002).
    • (2002) J Incl Phenom Macroc Chem , vol.42 , pp. 1-14
    • Liu, L.1    Guo, Q.-X.2
  • 64
    • 0002262216 scopus 로고
    • Effects of cyclodextrins on chemical stability of drugs in aqueous solutions
    • T. Loftsson, Effects of cyclodextrins on chemical stability of drugs in aqueous solutions. Drug Stability, 1, 22-33 (1995).
    • (1995) Drug Stability , vol.1 , pp. 22-33
    • Loftsson, T.1
  • 65
    • 22544450777 scopus 로고    scopus 로고
    • Stratum corneum lipids and water
    • P.W. Wertz, Stratum corneum lipids and water. Exog Dermatol, 3, 53-56 (2004).
    • (2004) Exog Dermatol , vol.3 , pp. 53-56
    • Wertz, P.W.1
  • 66
    • 33745001604 scopus 로고    scopus 로고
    • Mucin structure, aggregation, physiological functions and biomedical applications
    • R. Bansil, B.S. Turner, Mucin structure, aggregation, physiological functions and biomedical applications. Curr Opin Colloid Interface Sci, 11, 164-170 (2006).
    • (2006) Curr Opin Colloid Interface Sci , vol.11 , pp. 164-170
    • Bansil, R.1    Turner, B.S.2
  • 67
    • 0031925268 scopus 로고    scopus 로고
    • Human intestinal permeability
    • H. Lennernäs, Human intestinal permeability. J Pharm Sci, 87, 403-410 (1998).
    • (1998) J Pharm Sci , vol.87 , pp. 403-410
    • Lennernäs, H.1
  • 68
    • 0025803782 scopus 로고
    • A method for the determination of cellular permeability coefficients and aqueous boundary layer thickness in monolayers of intestinal epithelia (Caco-2) cells grown in permeable filter chambers
    • J.P. Karlsson, P. Artursson, A method for the determination of cellular permeability coefficients and aqueous boundary layer thickness in monolayers of intestinal epithelia (Caco-2) cells grown in permeable filter chambers. Int J Pharm, 71, 55-64 (1991).
    • (1991) Int J Pharm , vol.71 , pp. 55-64
    • Karlsson, J.P.1    Artursson, P.2
  • 69
    • 0344983259 scopus 로고    scopus 로고
    • Drug Discov Today
    • In vitro trans-monolayer permeability calculations: often forgotten assumptions
    • K.A. Youdim, A. Avdeef, N.J. Abbott, In vitro trans-monolayer permeability calculations: often forgotten assumptions. Drug Discov Today 8, 997-1003 (2003).
    • (2003) , vol.8 , pp. 997-1003
    • Youdim, K.A.1    Avdeef, A.2    Abbott, N.J.3
  • 70
    • 3242739976 scopus 로고    scopus 로고
    • PAMPA: A drug absorption in vitro model 11. Matching the in vivo unstirred water layer thickness by individual-well stirring in microtitre plates
    • A. Avdeef, P.E. Nielsen, O. Tsinman, PAMPA: A drug absorption in vitro model 11. Matching the in vivo unstirred water layer thickness by individual-well stirring in microtitre plates. Eur J Pharm Sci, 22, 365-374 (2004).
    • (2004) Eur J Pharm Sci , vol.22 , pp. 365-374
    • Avdeef, A.1    Nielsen, P.E.2    Tsinman, O.3
  • 71
    • 34547952465 scopus 로고    scopus 로고
    • Effect of the unstirredwater layer on permeability enhancement by hydrophilic cyclodextrins
    • M.E. Brewster, M. Noppe, J. Peeters, T. Loftsson, Effect of the unstirredwater layer on permeability enhancement by hydrophilic cyclodextrins. Int J Pharm, 342, 250-253 (2007).
    • (2007) Int J Pharm , vol.342 , pp. 250-253
    • Brewster, M.E.1    Noppe, M.2    Peeters, J.3    Loftsson, T.4
  • 72
    • 0002086622 scopus 로고
    • Physical chemical analysis of percutaneous absorption process from creams and ointments
    • T. Higuchi, Physical chemical analysis of percutaneous absorption process from creams and ointments. J Soc Cosmet Chem, 11(2), 85-97 (1960).
    • (1960) J Soc Cosmet Chem , vol.11 , Issue.2 , pp. 85-97
    • Higuchi, T.1
  • 73
    • 0015295910 scopus 로고
    • Total mathematical resolution of diffusion layer control of barrier flux
    • G.L. Flynn, O.S. Carpender, S.H. Yalkowsky, Total mathematical resolution of diffusion layer control of barrier flux. J Pharm Sci, 61, 312-314 (1972).
    • (1972) J Pharm Sci , vol.61 , pp. 312-314
    • Flynn, G.L.1    Carpender, O.S.2    Yalkowsky, S.H.3
  • 74
    • 0015358676 scopus 로고
    • Correlation and prediction of mass transport across membranes I: influence of alkyl chain length on flux-determining properties of barrier and diffusant
    • G.L. Flynn, S.H. Yalkowsky, Correlation and prediction of mass transport across membranes I: influence of alkyl chain length on flux-determining properties of barrier and diffusant. J Pharm Sci, 61, 838-852 (1972).
    • (1972) J Pharm Sci , vol.61 , pp. 838-852
    • Flynn, G.L.1    Yalkowsky, S.H.2
  • 75
    • 80051674971 scopus 로고    scopus 로고
    • Pharmaceutical applications of cyclodextrins: effects on drug permeation through biological membranes
    • T. Loftsson, M.E. Brewster, Pharmaceutical applications of cyclodextrins: effects on drug permeation through biological membranes. J Pharm Pharmacol, 63, 1119-1135 (2011).
    • (2011) J Pharm Pharmacol , vol.63 , pp. 1119-1135
    • Loftsson, T.1    Brewster, M.E.2
  • 76
    • 35349000733 scopus 로고    scopus 로고
    • Effects of cyclodextrins on drug delivery through biological membranes
    • T. Loftsson, S.B. Vogensen, M.E. Brewster, F. Konrásdóttir, Effects of cyclodextrins on drug delivery through biological membranes. J Pharm Sci, 96, 2532-2546 (2007).
    • (2007) J Pharm Sci , vol.96 , pp. 2532-2546
    • Loftsson, T.1    Vogensen, S.B.2    Brewster, M.E.3    Konrásdóttir, F.4
  • 79
    • 0027994727 scopus 로고
    • In-vitro hydrocortisone release from ointments in presence of cyclodextrins
    • A. Preiss, W. Mehnert, K.H. Frömming, In-vitro hydrocortisone release from ointments in presence of cyclodextrins. Pharmazie, 49, 902-906 (1994).
    • (1994) Pharmazie , vol.49 , pp. 902-906
    • Preiss, A.1    Mehnert, W.2    Frömming, K.H.3
  • 80
    • 0028830921 scopus 로고
    • Penetration of hydrocortisone into excised human skin under the influence of cyclodextrins
    • A. Preiss, W. Mehnert, K.-H. Frömming, Penetration of hydrocortisone into excised human skin under the influence of cyclodextrins. Pharmazie, 50, 121-126 (1995).
    • (1995) Pharmazie , vol.50 , pp. 121-126
    • Preiss, A.1    Mehnert, W.2    Frömming, K.-H.3
  • 81
    • 0026535548 scopus 로고
    • Preparation of drug: hydroxypropylcyclodextrin complexes by method using ethanol or aqueous ammonium hydroxide as co-solubilizers
    • J. Pitha, T. Hoshino, J. Torres-Labandeira, T. Irie, Preparation of drug: hydroxypropylcyclodextrin complexes by method using ethanol or aqueous ammonium hydroxide as co-solubilizers. Int J Pharm, 80, 253-258 (1992).
    • (1992) Int J Pharm , vol.80 , pp. 253-258
    • Pitha, J.1    Hoshino, T.2    Torres-Labandeira, J.3    Irie, T.4
  • 82
    • 0026510749 scopus 로고
    • Effects of ethanol on formation of inclusion complexes of hydroxypropylcyclodextrins with testosterone or with methyl organe
    • J. Pitha, T. Hoshino, Effects of ethanol on formation of inclusion complexes of hydroxypropylcyclodextrins with testosterone or with methyl organe. Int J Pharm, 80, 243-251 (1992).
    • (1992) Int J Pharm , vol.80 , pp. 243-251
    • Pitha, J.1    Hoshino, T.2
  • 83
    • 0344673395 scopus 로고    scopus 로고
    • Methods to enhance the complexation efficiency of cyclodextrins
    • T. Loftsson, M. Másson, J.F. Sigurjónsdóttir, Methods to enhance the complexation efficiency of cyclodextrins. STP Pharma Sci, 9, 237-242 (1999).
    • (1999) STP Pharma Sci , vol.9 , pp. 237-242
    • Loftsson, T.1    Másson, M.2    Sigurjónsdóttir, J.F.3
  • 84
    • 8244248457 scopus 로고    scopus 로고
    • Cyclodextrins: their future in drug formulation and delivery
    • V.J. Stella, R.A. Rajewski, Cyclodextrins: their future in drug formulation and delivery. Pharm Res, 14(5), 556-567 (1997).
    • (1997) Pharm Res , vol.14 , Issue.5 , pp. 556-567
    • Stella, V.J.1    Rajewski, R.A.2
  • 85
    • 33644555897 scopus 로고    scopus 로고
    • Influence of aqueous diffusion layer on passive drug diffusion from aqueous cyclodextrin solutions through biological membranes
    • T. Loftsson, F. Konrásdóttir, M. Másson, Influence of aqueous diffusion layer on passive drug diffusion from aqueous cyclodextrin solutions through biological membranes. Pharmazie, 61, 83-89 (2006).
    • (2006) Pharmazie , vol.61 , pp. 83-89
    • Loftsson, T.1    Konrásdóttir, F.2    Másson, M.3
  • 86
    • 30744469117 scopus 로고    scopus 로고
    • The effects of a new soluble dietary fiber on weight gain and selected blood parameters in rats
    • J.D. Artiss, K. Brogan, M. Brucal, M. Moghaddam, K.-L.C. Jen, The effects of a new soluble dietary fiber on weight gain and selected blood parameters in rats. Metab Clin Exp, 55, 195-202 (2006).
    • (2006) Metab Clin Exp , vol.55 , pp. 195-202
    • Artiss, J.D.1    Brogan, K.2    Brucal, M.3    Moghaddam, M.4    Jen, K.-L.C.5
  • 87
    • 0026041229 scopus 로고
    • Studies of cyclodextrin inclusion complexes. III. The pulmonary absorption of β-, DM-β-and HP-β-cyclodextrins in rabbits
    • H.M. Cabral Marques, J. Hadgraft, I.W. Kellaway, G. Taylor, Studies of cyclodextrin inclusion complexes. III. The pulmonary absorption of β-, DM-β-and HP-β-cyclodextrins in rabbits. Int J Pharm, 77, 297-302 (1991).
    • (1991) Int J Pharm , vol.77 , pp. 297-302
    • Cabral Marques, H.M.1    Hadgraft, J.2    Kellaway, I.W.3    Taylor, G.4
  • 88
    • 0346104870 scopus 로고    scopus 로고
    • Absorption enhancers in pulmonary protein delivery
    • A. Hussain, J.J. Arnold, M.A. Khan, F. Ahsan, Absorption enhancers in pulmonary protein delivery. J Control Rel, 94, 15-24 (2004).
    • (2004) J Control Rel , vol.94 , pp. 15-24
    • Hussain, A.1    Arnold, J.J.2    Khan, M.A.3    Ahsan, F.4
  • 90
    • 75149119371 scopus 로고    scopus 로고
    • A novel administration route of edaravone-II: mucosal absorption of edaravone from edaravone/hydroxypropyl-β-cyclodextrin complex solution including L-cysteine and sodium hydrogen sulfite
    • T. Sato, K. Mizuno, F. Ishii, A novel administration route of edaravone-II: mucosal absorption of edaravone from edaravone/hydroxypropyl-β-cyclodextrin complex solution including L-cysteine and sodium hydrogen sulfite. Pharmacology, 85, 88-94 (2010).
    • (2010) Pharmacology , vol.85 , pp. 88-94
    • Sato, T.1    Mizuno, K.2    Ishii, F.3
  • 91
    • 70349680609 scopus 로고    scopus 로고
    • Thermo-reversible flurbiprofen liquid suppository with HP-β-CD as a solubility enhancer: improvement of rectal bioavailability
    • J.K. Kim, M.S. Kim, J.S. Park, C.K. Kim, Thermo-reversible flurbiprofen liquid suppository with HP-β-CD as a solubility enhancer: improvement of rectal bioavailability. J Incl Phenom Macroc Chem, 64, 265-272 (2009).
    • (2009) J Incl Phenom Macroc Chem , vol.64 , pp. 265-272
    • Kim, J.K.1    Kim, M.S.2    Park, J.S.3    Kim, C.K.4
  • 93
    • 55749092785 scopus 로고    scopus 로고
    • Preparation and characterisation of natamycin: γ-cyclodextrin inclusion complex and its evaluation in vaginal mucoadhesive formulations
    • E. Cevher, D. Sȩnsoy, M. Zloh, L. Mülazimoǧlu, Preparation and characterisation of natamycin: γ-cyclodextrin inclusion complex and its evaluation in vaginal mucoadhesive formulations. J Pharm Sci, 97, 4319-4335 (2008).
    • (2008) J Pharm Sci , vol.97 , pp. 4319-4335
    • Cevher, E.1    Sȩnsoy, D.2    Zloh, M.3    Mülazimoǧlu, L.4
  • 94
    • 0024390449 scopus 로고
    • The pharmacology of antiglaucoma drugs
    • M.F. Sugrue, The pharmacology of antiglaucoma drugs. Pharm Ther, 43, 91-138 (1989).
    • (1989) Pharm Ther , vol.43 , pp. 91-138
    • Sugrue, M.F.1
  • 96
    • 0029060183 scopus 로고
    • Sulfobutyl ether β-cyclodextrin (SBE-β-CyD) in eye drops improves the tolerability of a topically applied pilocarpine prodrug in rabbits
    • T. Järvinen, K. Järvinen, A. Urtti, D. Thompson, V.J. Stella, Sulfobutyl ether β-cyclodextrin (SBE-β-CyD) in eye drops improves the tolerability of a topically applied pilocarpine prodrug in rabbits. J Ocul Pharmacol Ther, 11, 95-106 (1995).
    • (1995) J Ocul Pharmacol Ther , vol.11 , pp. 95-106
    • Järvinen, T.1    Järvinen, K.2    Urtti, A.3    Thompson, D.4    Stella, V.J.5
  • 97
    • 0030001340 scopus 로고    scopus 로고
    • Modified β-cyclodextrin (SBE7-β-CyD) with viscous vehicle improves the ocular delivery and tolerability of pilocarpine prodrug in rabbits
    • P. Jarho, K. Järvinen, A. Urtti, V.J. Stella, T. Järvinen, Modified β-cyclodextrin (SBE7-β-CyD) with viscous vehicle improves the ocular delivery and tolerability of pilocarpine prodrug in rabbits. J Pharm Pharmacol, 48, 264-270 (1996).
    • (1996) J Pharm Pharmacol , vol.48 , pp. 264-270
    • Jarho, P.1    Järvinen, K.2    Urtti, A.3    Stella, V.J.4    Järvinen, T.5
  • 98
    • 0028930838 scopus 로고
    • Ocular absorption and irritation of pilocarpine prodrug is modified with buffer, polymer, and cyclodextrin in the eyedrop
    • P. Suhonen, T. Jarvinen, K. Lehmussaari, T. Reunamaki, A. Urtti, Ocular absorption and irritation of pilocarpine prodrug is modified with buffer, polymer, and cyclodextrin in the eyedrop. Pharmaceutical Research, 12, 529-533 (1995).
    • (1995) Pharmaceutical Research , vol.12 , pp. 529-533
    • Suhonen, P.1    Jarvinen, T.2    Lehmussaari, K.3    Reunamaki, T.4    Urtti, A.5
  • 101
    • 0036408814 scopus 로고    scopus 로고
    • Influence of hydroxypropyl-β-cyclodextrin on transdermal permeation and skin accumulation of oxybenzone
    • L.A. Felton, C.J. Wiley, D.A. Godwin, Influence of hydroxypropyl-β-cyclodextrin on transdermal permeation and skin accumulation of oxybenzone. Drug Devel Ind Pharm, 28, 1117-1124 (2002).
    • (2002) Drug Devel Ind Pharm , vol.28 , pp. 1117-1124
    • Felton, L.A.1    Wiley, C.J.2    Godwin, D.A.3
  • 102
    • 43249093112 scopus 로고    scopus 로고
    • Influence of hydroxypropyl-β-cyclodextrin on transdermal penetration and photostability of avobenzone
    • J. Yang, C.J. Wiley, D.A. Godwin, L.A. Felton, Influence of hydroxypropyl-β-cyclodextrin on transdermal penetration and photostability of avobenzone. Eur J Pharm Biopharm, 69, 605-612 (2008).
    • (2008) Eur J Pharm Biopharm , vol.69 , pp. 605-612
    • Yang, J.1    Wiley, C.J.2    Godwin, D.A.3    Felton, L.A.4
  • 103
    • 1242343605 scopus 로고    scopus 로고
    • Influence of cyclodextrin complexation on the in vivo photoprotective effects of oxybenzone
    • L.A. Felton, C.J.Wiley, D.A. Godwin, Influence of cyclodextrin complexation on the in vivo photoprotective effects of oxybenzone. Drug Devel Ind Pharm, 30, 95-102 (2004).
    • (2004) Drug Devel Ind Pharm , vol.30 , pp. 95-102
    • Felton, L.A.1    Wiley, C.J.2    Godwin, D.A.3
  • 104
    • 18844392003 scopus 로고    scopus 로고
    • Inclusion complexation of the sunscreen 2-hydroxy-4-methoxy benzophenone (oxybenzone) with hydroxypropyl-β-cyclodextrin: effect on membrane diffusion
    • V. Sarveiya, J.F. Templeton, H.A.E. Benson, Inclusion complexation of the sunscreen 2-hydroxy-4-methoxy benzophenone (oxybenzone) with hydroxypropyl-β-cyclodextrin: effect on membrane diffusion. J Incl Phenom Macroc Chem, 49, 275-281 (2004).
    • (2004) J Incl Phenom Macroc Chem , vol.49 , pp. 275-281
    • Sarveiya, V.1    Templeton, J.F.2    Benson, H.A.E.3
  • 105
    • 1242337285 scopus 로고    scopus 로고
    • Solubilizing excipients in oral and injectable formulations
    • R.G. Strickley, Solubilizing excipients in oral and injectable formulations. Pharm Res, 21, 201-230 (2004).
    • (2004) Pharm Res , vol.21 , pp. 201-230
    • Strickley, R.G.1
  • 106
    • 84866094840 scopus 로고    scopus 로고
    • Handbook on Injectable Drugs
    • 12th edn. Bethesda, MD: American Society of Health-System Pharmacists
    • L.A. Trissel (ed.), Handbook on Injectable Drugs. 12th edn. Bethesda, MD: American Society of Health-System Pharmacists (2003).
    • (2003)
    • Trissel, L.A.1
  • 108
    • 78649906619 scopus 로고    scopus 로고
    • Parenteral delivery of HPβCD: effects on drug-HSA binding
    • S.V. Kurkov, T. Loftsson, M. Messner, D. Madden, Parenteral delivery of HPβCD: effects on drug-HSA binding. AAPS PharmSciTech, 11, 1152-1158 (2010).
    • (2010) AAPS PharmSciTech , vol.11 , pp. 1152-1158
    • Kurkov, S.V.1    Loftsson, T.2    Messner, M.3    Madden, D.4
  • 109
    • 0032994776 scopus 로고    scopus 로고
    • Comparison of the IV pharmacokinetics in sheep of miconazole-cyclodextrin solutions and a micellar solution
    • G. Piel, B. Evrard, T. Van Hees, L. Delattre, Comparison of the IV pharmacokinetics in sheep of miconazole-cyclodextrin solutions and a micellar solution. Int J Pharm, 180, 41-45 (1999).
    • (1999) Int J Pharm , vol.180 , pp. 41-45
    • Piel, G.1    Evrard, B.2    Van Hees, T.3    Delattre, L.4
  • 110
    • 33645022281 scopus 로고    scopus 로고
    • Preparation, characterization and in vivo evaluation of formulation of baicalein with hydroxypropyl-β-cyclodextrin
    • J. Liu, L. Qiu, J. Gao, Y. Jin, Preparation, characterization and in vivo evaluation of formulation of baicalein with hydroxypropyl-β-cyclodextrin. Int J Pharm, 312, 137-143 (2006).
    • (2006) Int J Pharm , vol.312 , pp. 137-143
    • Liu, J.1    Qiu, L.2    Gao, J.3    Jin, Y.4
  • 111
    • 0025845183 scopus 로고
    • Effect of hydrotropic substances on the complexation of sprangly soluble drugs with cyclodextrin derivatives and the influence of cyclodextrin complexation on the pharmacokinetics of the drugs
    • B.W. Muller, E. Alberts, Effect of hydrotropic substances on the complexation of sprangly soluble drugs with cyclodextrin derivatives and the influence of cyclodextrin complexation on the pharmacokinetics of the drugs. J Pharm Sci, 80, 599-604 (1991).
    • (1991) J Pharm Sci , vol.80 , pp. 599-604
    • Muller, B.W.1    Alberts, E.2
  • 112
    • 0037974454 scopus 로고    scopus 로고
    • The pahrmacokinetics and pharmacodynamics of propofol in modified cyclodextrin formulation (Captisol®) versus propofol in a lipid formulation (Diprivan®): an electroencephalographic and hemodynamic study in a porcine model
    • T.D. Egan, S.E. Kern, K.B. Johnson, N.L. Pace, The pahrmacokinetics and pharmacodynamics of propofol in modified cyclodextrin formulation (Captisol®) versus propofol in a lipid formulation (Diprivan®): an electroencephalographic and hemodynamic study in a porcine model. Anesth Analg, 97, 72-79 (2003).
    • (2003) Anesth Analg , vol.97 , pp. 72-79
    • Egan, T.D.1    Kern, S.E.2    Johnson, K.B.3    Pace, N.L.4
  • 113
    • 36248980358 scopus 로고    scopus 로고
    • The effects of pharmaceutical excipients on drug disposition
    • T.R. Buggins, P.A. Dickinson, G. Taylor, The effects of pharmaceutical excipients on drug disposition. Adv Drug Deliv Rev, 59, 1482-1503 (2007).
    • (2007) Adv Drug Deliv Rev , vol.59 , pp. 1482-1503
    • Buggins, T.R.1    Dickinson, P.A.2    Taylor, G.3
  • 114
    • 0029048935 scopus 로고
    • The effect of SBE4-β-CD on i.m. prednisolone pharmacokinetics and tissue damage in rabbits: comparison to a co-solvent solution and a water-soluble prodrug
    • V.J. Stella, H.K. Lee, D.O. Thompson, The effect of SBE4-β-CD on i.m. prednisolone pharmacokinetics and tissue damage in rabbits: comparison to a co-solvent solution and a water-soluble prodrug. Int J Pharm, 120, 197-204 (1995).
    • (1995) Int J Pharm , vol.120 , pp. 197-204
    • Stella, V.J.1    Lee, H.K.2    Thompson, D.O.3
  • 115
    • 4844220197 scopus 로고    scopus 로고
    • In vitro and in vivo evaluation of a sulfobutyl ether β-cyclodextrin enabled etomidate formulation
    • M.P. McIntosh, N. Schwarting, R.A. Rajewski, In vitro and in vivo evaluation of a sulfobutyl ether β-cyclodextrin enabled etomidate formulation. J Pharm Sci, 93, 2585-2594 (2004).
    • (2004) J Pharm Sci , vol.93 , pp. 2585-2594
    • McIntosh, M.P.1    Schwarting, N.2    Rajewski, R.A.3
  • 116
    • 0036769470 scopus 로고    scopus 로고
    • Hydroxypropyl-b-cyclodextrin-flutamide inclusion complex. II. Oral and intravenous pharmacokinetics of flutamide in the rat
    • Z. Zuo, Y.K. Tam, J. Diakur, L.I. Wiebe, Hydroxypropyl-b-cyclodextrin-flutamide inclusion complex. II. Oral and intravenous pharmacokinetics of flutamide in the rat. J Pharm Pharmaceut Sci, 5, 292-298 (2002).
    • (2002) J Pharm Pharmaceut Sci , vol.5 , pp. 292-298
    • Zuo, Z.1    Tam, Y.K.2    Diakur, J.3    Wiebe, L.I.4
  • 117
    • 33749646868 scopus 로고    scopus 로고
    • New drug sugammadex: A selective relaxant binding agent
    • M. Welliver, New drug sugammadex: A selective relaxant binding agent. AANA Journal, 74, 357-363 (2006).
    • (2006) AANA Journal , vol.74 , pp. 357-363
    • Welliver, M.1
  • 118
    • 32644434566 scopus 로고    scopus 로고
    • Alteration of the intravenous pharmacokinetics of a synthetic ozonide antimalarial in the presence of a modified cyclodextrin
    • S.A. Charman, C.S. Perry, F.C.K. Chiu, K.A. McIntosh, R.J. Prankerd,W.N. Charman, Alteration of the intravenous pharmacokinetics of a synthetic ozonide antimalarial in the presence of a modified cyclodextrin. J Pharm Sci, 95, 256-267 (2006).
    • (2006) J Pharm Sci , vol.95 , pp. 256-267
    • Charman, S.A.1    Perry, C.S.2    Chiu, F.C.K.3    McIntosh, K.A.4    Prankerd, R.J.5    Charman, W.N.6
  • 119
    • 3242697762 scopus 로고    scopus 로고
    • Subchronic oral toxicity studies with a-cyclodextrin in rats
    • B.A.R. Lina, A. Bär, Subchronic oral toxicity studies with a-cyclodextrin in rats. Regul Toxicol Pharmacol, 39, S14-S26 (2004).
    • (2004) Regul Toxicol Pharmacol , vol.39
    • Lina, B.A.R.1    Bär, A.2
  • 120
    • 3242740924 scopus 로고    scopus 로고
    • Subchronic (13-week) oral toxicity study of a-cyclodextrin in dogs
    • B.A.R. Lina, A. Bär, Subchronic (13-week) oral toxicity study of a-cyclodextrin in dogs, Regul Toxicol Pharmacol, 39, S27-S33 (2004).
    • (2004) Regul Toxicol Pharmacol , vol.39
    • Lina, B.A.R.1    Bär, A.2
  • 122
    • 21844459973 scopus 로고    scopus 로고
    • 2-Hydroxypropyl-b-cyclodextrin (HP-b-CD): a toxicology review
    • S. Gould, R.C. Scott, 2-Hydroxypropyl-b-cyclodextrin (HP-b-CD): a toxicology review. Food Chem Toxicol, 43, 1451-1459 (2005).
    • (2005) Food Chem Toxicol , vol.43 , pp. 1451-1459
    • Gould, S.1    Scott, R.C.2
  • 123
    • 0031042310 scopus 로고    scopus 로고
    • Cyclodextrins-enabling excipients: their present and future use in pharmaceuticals
    • D.O. Thompson, Cyclodextrins-enabling excipients: their present and future use in pharmaceuticals. Crit Rev Ther Drug Carrier Syst, 14, 1-104 (1997).
    • (1997) Crit Rev Ther Drug Carrier Syst , vol.14 , pp. 1-104
    • Thompson, D.O.1
  • 124
    • 16344364096 scopus 로고    scopus 로고
    • Design and evaluation of cyclodextrin-based drug formulation
    • K. Uekama, Design and evaluation of cyclodextrin-based drug formulation. Chem Pharm Bull, 52, 900-915 (2004).
    • (2004) Chem Pharm Bull , vol.52 , pp. 900-915
    • Uekama, K.1
  • 125
    • 79955152821 scopus 로고    scopus 로고
    • Cyclodextrins and their Complexes
    • Weinheim:Wiley-VCH Verlag
    • H. Dodziuk (ed.), Cyclodextrins and their Complexes. Weinheim:Wiley-VCH Verlag (2006).
    • (2006)
    • Dodziuk, H.1
  • 126
    • 29944438882 scopus 로고    scopus 로고
    • Solubility of cyclomaltooligosaccharides (cyclodextrins) in H2O and D2O: a comparative study
    • E. Sabadini, T. Cosgrove, F.C. Egídio, Solubility of cyclomaltooligosaccharides (cyclodextrins) in H2O and D2O: a comparative study. Carbohydr Res, 341, 270-274 (2006).
    • (2006) Carbohydr Res , vol.341 , pp. 270-274
    • Sabadini, E.1    Cosgrove, T.2    Egídio, F.C.3
  • 127
    • 0029018771 scopus 로고
    • Population characteristics of cyclodextrin complex stabilities in aqueous solution
    • K.A. Connors, Population characteristics of cyclodextrin complex stabilities in aqueous solution. J Pharm Sci, 84, 843-848 (1995).
    • (1995) J Pharm Sci , vol.84 , pp. 843-848
    • Connors, K.A.1
  • 128
    • 0345179962 scopus 로고    scopus 로고
    • The stability of cyclodextrin complexes in solution
    • K.A. Connors, The stability of cyclodextrin complexes in solution. Chem Rev, 97, 1325-1357 (1997).
    • (1997) Chem Rev , vol.97 , pp. 1325-1357
    • Connors, K.A.1
  • 129
    • 0028111609 scopus 로고
    • The effect of watersoluble polymers on drug-cyclodextrin complexation
    • T. Loftsson, H. Fridriksdottir, A.M. Sigurdardottir, H. Ueda, The effect of watersoluble polymers on drug-cyclodextrin complexation. Int J Pharm, 110, 169-177 (1994).
    • (1994) Int J Pharm , vol.110 , pp. 169-177
    • Loftsson, T.1    Fridriksdottir, H.2    Sigurdardottir, A.M.3    Ueda, H.4
  • 130
    • 0024244571 scopus 로고
    • Studies of the effect of pH, temperature and ring size on the complexation of phenytoin with cyclodextrins
    • F.A. Menard, M.G. Dedhiya, C.T. Rhodes, Studies of the effect of pH, temperature and ring size on the complexation of phenytoin with cyclodextrins. Pharm Acta Helv, 63, 303-308 (1988).
    • (1988) Pharm Acta Helv , vol.63 , pp. 303-308
    • Menard, F.A.1    Dedhiya, M.G.2    Rhodes, C.T.3
  • 131
    • 0024563503 scopus 로고
    • Solubilization and interaction of naproxen with cyclodextrinsin aqueous solution and in the solid state
    • G.P. Bettinetti, P. Mura, A. Liguori, G. Bramanti, F. Giordano, Solubilization and interaction of naproxen with cyclodextrinsin aqueous solution and in the solid state. Farmaco, 44, 195-213 (1989).
    • (1989) Farmaco , vol.44 , pp. 195-213
    • Bettinetti, G.P.1    Mura, P.2    Liguori, A.3    Bramanti, G.4    Giordano, F.5
  • 132
    • 0025337885 scopus 로고
    • Inclusion complexes of purine nucleosides with cyclodextrins. 2. Investigation of inclusion complex-geometry and cavity microenvironment
    • T.-X. Xiang, B.D. Anderson, Inclusion complexes of purine nucleosides with cyclodextrins. 2. Investigation of inclusion complex-geometry and cavity microenvironment. Int J Pharm, 59, 45-55 (1990).
    • (1990) Int J Pharm , vol.59 , pp. 45-55
    • Xiang, T.-X.1    Anderson, B.D.2
  • 133
    • 0025165028 scopus 로고
    • Physicochemical aspects of the complexation of some drugs with cyclodextrins
    • F.A. Menard, M.G. Dedhiya, C.T. Rhodes, Physicochemical aspects of the complexation of some drugs with cyclodextrins. Drug Devel Ind Pharm, 16, 91-113 (1990).
    • (1990) Drug Devel Ind Pharm , vol.16 , pp. 91-113
    • Menard, F.A.1    Dedhiya, M.G.2    Rhodes, C.T.3
  • 134
    • 0036173525 scopus 로고    scopus 로고
    • Interaction of naproxen with noncrystalline acetyl β-and acetyl γ-cyclodextrins in the solid and liquid state
    • G. Bettinetti, P. Mura, M.T. Faucci, M. Sorrent, M. Setti, Interaction of naproxen with noncrystalline acetyl β-and acetyl γ-cyclodextrins in the solid and liquid state. Eur J Pharm Sci, 15, 21-29 (2002).
    • (2002) Eur J Pharm Sci , vol.15 , pp. 21-29
    • Bettinetti, G.1    Mura, P.2    Faucci, M.T.3    Sorrent, M.4    Setti, M.5
  • 136
    • 0035067785 scopus 로고    scopus 로고
    • The influence of polyvinylpyrrolidone on naproxen complexation with hydroxypropyl-β-cyclodextrin
    • P. Mura, M.T. Faucci, G.P. Bettinetti, The influence of polyvinylpyrrolidone on naproxen complexation with hydroxypropyl-β-cyclodextrin. Eur J Pharm Sci, 13, 187-194 (2001).
    • (2001) Eur J Pharm Sci , vol.13 , pp. 187-194
    • Mura, P.1    Faucci, M.T.2    Bettinetti, G.P.3
  • 137
    • 0033805216 scopus 로고    scopus 로고
    • Thermodynamics of binding of neutral molecules to sulfobutyl ether b-cyclodextrins (SBE-β-CDs): the effect of total degree of substitution
    • V. Zia, R.A. Rajewski, V.J. Stella, Thermodynamics of binding of neutral molecules to sulfobutyl ether b-cyclodextrins (SBE-β-CDs): the effect of total degree of substitution. Pharm Res, 17, 936-941 (2000).
    • (2000) Pharm Res , vol.17 , pp. 936-941
    • Zia, V.1    Rajewski, R.A.2    Stella, V.J.3
  • 138
    • 0024469572 scopus 로고
    • Effects of 2-hydroxypropyl-β-cyclodextrin on the aqueous solubility of drugs and transdermal delivery of 17β-estradiol
    • T. Loftsson, N. Bodor, Effects of 2-hydroxypropyl-β-cyclodextrin on the aqueous solubility of drugs and transdermal delivery of 17β-estradiol. Acta Pharm Nord, 1, 185-194 (1989).
    • (1989) Acta Pharm Nord , vol.1 , pp. 185-194
    • Loftsson, T.1    Bodor, N.2
  • 139
    • 0027245886 scopus 로고
    • Complexation of moricizine with nicotinamide and evaluation of the complexation constants by various methods
    • M.A. Hussain, R.C. Diluccio, M.B. Maurin, Complexation of moricizine with nicotinamide and evaluation of the complexation constants by various methods. J Pharm Sci, 82, 77-79 (1993).
    • (1993) J Pharm Sci , vol.82 , pp. 77-79
    • Hussain, M.A.1    Diluccio, R.C.2    Maurin, M.B.3
  • 141
    • 0031742889 scopus 로고    scopus 로고
    • Combined effect of complexation and pH on solubilization
    • P. Li, E. Tabibi, S.H. Yalkowsky, Combined effect of complexation and pH on solubilization. J Pharm Sci, 87, 1535-1537 (1998).
    • (1998) J Pharm Sci , vol.87 , pp. 1535-1537
    • Li, P.1    Tabibi, E.2    Yalkowsky, S.H.3
  • 142
    • 0032581196 scopus 로고    scopus 로고
    • Development of a non-surfactant parenteral formulation of miconazole by the use of cyclodextrins
    • G. Piel, B. Evrard, M. Fillet, G. Llabres, L. Delattre, Development of a non-surfactant parenteral formulation of miconazole by the use of cyclodextrins. Int J Pharm, 169, 15-22 (1998).
    • (1998) Int J Pharm , vol.169 , pp. 15-22
    • Piel, G.1    Evrard, B.2    Fillet, M.3    Llabres, G.4    Delattre, L.5
  • 143
    • 0034887576 scopus 로고    scopus 로고
    • Cyclodextrin complexes of salts of acidic drugs. Thermodynamic properties, structural features, and pharmaceutical applications
    • E. Redenti, L. Szente, J. Szejtli, Cyclodextrin complexes of salts of acidic drugs. Thermodynamic properties, structural features, and pharmaceutical applications. J Pharm Sci, 90, 979-986 (2001).
    • (2001) J Pharm Sci , vol.90 , pp. 979-986
    • Redenti, E.1    Szente, L.2    Szejtli, J.3
  • 144
    • 0242270818 scopus 로고    scopus 로고
    • The effect of pH and triethanolamine on sulfisoxazole complexation with hydroxypropyl-β-cyclodextrin
    • G. Granero, C. Granero, M. Longhi, The effect of pH and triethanolamine on sulfisoxazole complexation with hydroxypropyl-β-cyclodextrin. Eur J Pharm Sci, 20, 285-293 (2003).
    • (2003) Eur J Pharm Sci , vol.20 , pp. 285-293
    • Granero, G.1    Granero, C.2    Longhi, M.3
  • 145
    • 1642419522 scopus 로고    scopus 로고
    • Preparation of solid drug/cyclodextrin complexes of acidic and basic drugs
    • T. Loftsson, H.H. Sigursson, M. Másson, N. Schipper, Preparation of solid drug/cyclodextrin complexes of acidic and basic drugs. Pharmazie, 59, 25-29 (2004).
    • (2004) Pharmazie , vol.59 , pp. 25-29
    • Loftsson, T.1    Sigursson, H.H.2    Másson, M.3    Schipper, N.4
  • 146
    • 0027177561 scopus 로고
    • Solubilization of thiazolobenzimidazole using a combination of pH adjustment and complexation with 2-hydroxypropyl-β-cyclodextrin
    • A.Y. Tinwalla, B.L. Hoesterey, T.-X. Xiang, K. Lim, B.D. Anderson, Solubilization of thiazolobenzimidazole using a combination of pH adjustment and complexation with 2-hydroxypropyl-β-cyclodextrin. Pharm Res, 10, 1136-1143 (1993).
    • (1993) Pharm Res , vol.10 , pp. 1136-1143
    • Tinwalla, A.Y.1    Hoesterey, B.L.2    Xiang, T.-X.3    Lim, K.4    Anderson, B.D.5
  • 147
    • 7344243724 scopus 로고    scopus 로고
    • Study of β-cyclodextrinketakonazole-tartaric acid multicomponent non-covalent association by positive and netagive ionspray mass spectrometry
    • A. Selva, E. Redenti, P. Ventura, M. Zanol, B. Casetta, Study of β-cyclodextrinketakonazole-tartaric acid multicomponent non-covalent association by positive and netagive ionspray mass spectrometry. J Mass Sepectrom, 33, 729-734 (1998).
    • (1998) J Mass Sepectrom , vol.33 , pp. 729-734
    • Selva, A.1    Redenti, E.2    Ventura, P.3    Zanol, M.4    Casetta, B.5
  • 149
    • 0033951798 scopus 로고    scopus 로고
    • Drug/cyclodextrin/hydroxy acid multicomponent systems. Properties and pharmaceutical applications
    • E. Redenti, L. Szente, J. Szejtli, Drug/cyclodextrin/hydroxy acid multicomponent systems. Properties and pharmaceutical applications. J Pharm Sci, 89, 1-8 (2000).
    • (2000) J Pharm Sci , vol.89 , pp. 1-8
    • Redenti, E.1    Szente, L.2    Szejtli, J.3
  • 150
    • 0038121683 scopus 로고    scopus 로고
    • Ternary systems of naproxen with hydroxypropyl-β-cyclodextrin and aminoacids
    • P. Mura, F. Maestrelli, M. Cirri, Ternary systems of naproxen with hydroxypropyl-β-cyclodextrin and aminoacids. Int J Pharm, 260, 293-302 (2003).
    • (2003) Int J Pharm , vol.260 , pp. 293-302
    • Mura, P.1    Maestrelli, F.2    Cirri, M.3
  • 151
    • 0031728704 scopus 로고    scopus 로고
    • Increasing the cyclodextrin complexation of drugs and drug biovailability through addition of water-soluble polymers
    • T. Loftsson, Increasing the cyclodextrin complexation of drugs and drug biovailability through addition of water-soluble polymers. Pharmazie, 53, 733-740 (1998).
    • (1998) Pharmazie , vol.53 , pp. 733-740
    • Loftsson, T.1
  • 152
    • 1842451466 scopus 로고    scopus 로고
    • The effects of water-soluble polymers on cyclodextrins and cyclodextrin solubilization of drugs
    • T. Loftsson, M. Másson, The effects of water-soluble polymers on cyclodextrins and cyclodextrin solubilization of drugs. J Drug Del Sci Tech, 14, 35-43 (2004).
    • (2004) J Drug Del Sci Tech , vol.14 , pp. 35-43
    • Loftsson, T.1    Másson, M.2
  • 153
    • 0037426683 scopus 로고    scopus 로고
    • Liquid formulation of a novel non-fluorinated topical quinolone, T-3912, utilizing the synergic solubilizing effect of the combined use of magnesium ions and hydroxypropyl-β-cyclodextrin
    • T. Yamakawa, S. Nishimura, Liquid formulation of a novel non-fluorinated topical quinolone, T-3912, utilizing the synergic solubilizing effect of the combined use of magnesium ions and hydroxypropyl-β-cyclodextrin. J Control Rel, 86, 101-113 (2003).
    • (2003) J Control Rel , vol.86 , pp. 101-113
    • Yamakawa, T.1    Nishimura, S.2
  • 155
    • 0032742298 scopus 로고    scopus 로고
    • Combined effect of cosolvent and cyclodextrin on solubilization of nonpolar drugs
    • P. Li, L. Zhao, S.H. Yalkowsky, Combined effect of cosolvent and cyclodextrin on solubilization of nonpolar drugs. J Pharm Sci, 88, 1107-1111 (1999).
    • (1999) J Pharm Sci , vol.88 , pp. 1107-1111
    • Li, P.1    Zhao, L.2    Yalkowsky, S.H.3
  • 156
    • 0034949440 scopus 로고    scopus 로고
    • Effect of cyclodextrin charge on complexation of neutral and charged substrates: comparison of (SBE)7M-β-CD to HP-β-CD
    • V. Zia, R.A. Rajewski, V.J. Stella, Effect of cyclodextrin charge on complexation of neutral and charged substrates: comparison of (SBE)7M-β-CD to HP-β-CD. Pharm Res, 18, 667-673 (2001).
    • (2001) Pharm Res , vol.18 , pp. 667-673
    • Zia, V.1    Rajewski, R.A.2    Stella, V.J.3
  • 157
    • 21344433057 scopus 로고    scopus 로고
    • Cyclodextrin solubilization of the antibacterial agents triclosan and triclocarban: effect of ionization and polymers
    • T. Loftsson, Í.B. Össurardot́tir, M. Duan, N. Zhao, T. Thorsteinsson, M. Maśson, Cyclodextrin solubilization of the antibacterial agents triclosan and triclocarban: effect of ionization and polymers. J Incl Phenom Macroc Chem, 52, 109-117 (2005).
    • (2005) J Incl Phenom Macroc Chem , vol.52 , pp. 109-117
    • Loftsson, T.1    Össurardot́tir, B.2    Duan, M.3    Zhao, N.4    Thorsteinsson, T.5    Maśson, M.6
  • 159
    • 59649115338 scopus 로고    scopus 로고
    • In vitro evaluation of natural and methylated cyclodextrins as buccal permeation enhancing system for omeprazole delivery
    • A. Figueiras, J. Hombach, F. Veiga, A. Bernkop-Schnürch, In vitro evaluation of natural and methylated cyclodextrins as buccal permeation enhancing system for omeprazole delivery. Eur J Pharm Biopharm, 71, 339-345 (2009).
    • (2009) Eur J Pharm Biopharm , vol.71 , pp. 339-345
    • Figueiras, A.1    Hombach, J.2    Veiga, F.3    Bernkop-Schnürch, A.4
  • 160
    • 70350630424 scopus 로고    scopus 로고
    • Novel cyclodextrin-based film formulation intended for buccal delivery of atenolol
    • M. Jug, M. Bećirević-Laćan, S. Bengez, Novel cyclodextrin-based film formulation intended for buccal delivery of atenolol. Drug Devel Ind Pharm, 35, 796-807 (2009).
    • (2009) Drug Devel Ind Pharm , vol.35 , pp. 796-807
    • Jug, M.1    Bećirević-Laćan, M.2    Bengez, S.3
  • 161
    • 70349208449 scopus 로고    scopus 로고
    • Cyclodextrins and chitosan derivatives in sublingual delivery of low solubility peptides: A study using cyclosporin A, alpha-cyclodextrin and quaternary chitosan N-betainate
    • J. Mannila, K. Jarvinen, J. Holappa, L. Matilainen, S. Auriola, P. Jarho, Cyclodextrins and chitosan derivatives in sublingual delivery of low solubility peptides: A study using cyclosporin A, alpha-cyclodextrin and quaternary chitosan N-betainate. Int J Pharm, 381, 19-24 (2010).
    • (2010) Int J Pharm , vol.381 , pp. 19-24
    • Mannila, J.1    Jarvinen, K.2    Holappa, J.3    Matilainen, L.4    Auriola, S.5    Jarho, P.6
  • 162
    • 0345580769 scopus 로고    scopus 로고
    • Increased bioavailability of clomipramine after sublingual administration in rats
    • S.D. Yoo, B.M. Yoon, H.S. Lee, K.C. Lee, Increased bioavailability of clomipramine after sublingual administration in rats. J Pharm Sci, 88, 1119-1121 (1999).
    • (1999) J Pharm Sci , vol.88 , pp. 1119-1121
    • Yoo, S.D.1    Yoon, B.M.2    Lee, H.S.3    Lee, K.C.4
  • 163
    • 0030573061 scopus 로고    scopus 로고
    • Bioavailability of danazolhydroxypropyl-β-cyclodextrin complex by different routes of administration
    • S.I.F. Badawy, M.M. Ghorab, C.M. Adeyeye, Bioavailability of danazolhydroxypropyl-β-cyclodextrin complex by different routes of administration, Int J Pharm, 145, 137-143 (1996).
    • (1996) Int J Pharm , vol.145 , pp. 137-143
    • Badawy, S.I.F.1    Ghorab, M.M.2    Adeyeye, C.M.3
  • 164
    • 0035998952 scopus 로고    scopus 로고
    • Development and in vivo evaluation of buccal tablets prepared using danazol-sulfobutylether 7 β-cyclodextrin (SBE 7) complexes
    • A.C. Jain, B.J. Aungst, M.C. Adeyeye, Development and in vivo evaluation of buccal tablets prepared using danazol-sulfobutylether 7 β-cyclodextrin (SBE 7) complexes, J Pharm Sci, 91, 1659-1668 (2002).
    • (2002) J Pharm Sci , vol.91 , pp. 1659-1668
    • Jain, A.C.1    Aungst, B.J.2    Adeyeye, M.C.3
  • 165
    • 0027134855 scopus 로고
    • Bioequivalence of 17β-estradiol hydroxypropyl-β-cyclodextrin complex in postmenopausal women
    • T.J. Hoon, M.Y. Dawood, F.S. Khan-Dawood, J. Ramos, R.L. Batenhorst, Bioequivalence of 17β-estradiol hydroxypropyl-β-cyclodextrin complex in postmenopausal women. J Clin Pharmacology, 33, 1116-1121 (1993).
    • (1993) J Clin Pharmacology , vol.33 , pp. 1116-1121
    • Hoon, T.J.1    Dawood, M.Y.2    Khan-Dawood, F.S.3    Ramos, J.4    Batenhorst, R.L.5
  • 168
    • 0025171523 scopus 로고
    • Nasal absorption enhancement of 17β-estradiol by dimethyl-β-cyclodextrin in rabbits and rats
    • W.A.J.J. Hermens, M.J.M. Deurloo, S.G. Romeijn, J.C. Verhoef, F.W.H.M. Mercus, Nasal absorption enhancement of 17β-estradiol by dimethyl-β-cyclodextrin in rabbits and rats. Pharm Res, 7, 500-503 (1990).
    • (1990) Pharm Res , vol.7 , pp. 500-503
    • Hermens, W.A.J.J.1    Deurloo, M.J.M.2    Romeijn, S.G.3    Verhoef, J.C.4    Mercus, F.W.H.M.5
  • 171
    • 68349139720 scopus 로고    scopus 로고
    • Optimization of spray-drying process variables for dry powder inhalation (DPI) formulations of corticosteroid/cyclodextrin inclusion complexes
    • H. Cabral-Marques, R. Almeida, Optimization of spray-drying process variables for dry powder inhalation (DPI) formulations of corticosteroid/cyclodextrin inclusion complexes. Eur J Pharm Biopharm, 73, 121-129 (2009).
    • (2009) Eur J Pharm Biopharm , vol.73 , pp. 121-129
    • Cabral-Marques, H.1    Almeida, R.2
  • 172
    • 0037841661 scopus 로고    scopus 로고
    • Pulmonary deposition of a budesonide/γ-cyclodextrin complex in vitro
    • T. Kinnarinen, P. Jarho, K. Järvinen, T. Järvinen, Pulmonary deposition of a budesonide/γ-cyclodextrin complex in vitro, J Control Rel, 90, 197-205 (2003).
    • (2003) J Control Rel , vol.90 , pp. 197-205
    • Kinnarinen, T.1    Jarho, P.2    Järvinen, K.3    Järvinen, T.4
  • 173
    • 33745489026 scopus 로고    scopus 로고
    • In vitro evaluation of cyclodextrin complexation on pulmonary deposition of a peptide, cyclosporin, A
    • L. Matilainen, K. Jarvinen, T. Toropainen, E. Nasi, S. Auriola, T. Jarvinen, P. Jarho, In vitro evaluation of cyclodextrin complexation on pulmonary deposition of a peptide, cyclosporin, A. Int J Pharm, 318, 41-48 (2006).
    • (2006) Int J Pharm , vol.318 , pp. 41-48
    • Matilainen, L.1    Jarvinen, K.2    Toropainen, T.3    Nasi, E.4    Auriola, S.5    Jarvinen, T.6    Jarho, P.7
  • 174
    • 77549085772 scopus 로고    scopus 로고
    • Eur J Pharm Sci
    • In vitro characterization and pharmacokinetics in mice following pulmonary delivery of itraconazole as cyclodextrin solubilized solution
    • W. Yang, K.T. Chow, B. Lang, N.P. Wiederhold, K.P. Johnston, R.O. Williams, In vitro characterization and pharmacokinetics in mice following pulmonary delivery of itraconazole as cyclodextrin solubilized solution, Eur J Pharm Sci, 39, 336-347 (2010).
    • (2010) , vol.39 , pp. 336-347
    • Yang, W.1    Chow, K.T.2    Lang, B.3    Wiederhold, N.P.4    Johnston, K.P.5    Williams, R.O.6
  • 175
    • 84968847606 scopus 로고    scopus 로고
    • Formulations Containing propofol and a Sulfoalkyl Ether Cyclodextrin
    • ed., US: Cydex, InC
    • D.O. Thompson, G.L. Mosher, Formulations Containing propofol and a Sulfoalkyl Ether Cyclodextrin. ed., US: Cydex, InC. (2006).
    • (2006)
    • Thompson, D.O.1    Mosher, G.L.2
  • 176
    • 10444279209 scopus 로고    scopus 로고
    • Cyclodextrin-based pharmaceutics: Past, present and future
    • M.E. Davis, M.E. Brewster, Cyclodextrin-based pharmaceutics: Past, present and future. Nature Rev, 3, 1023-1035 (2004).
    • (2004) Nature Rev , vol.3 , pp. 1023-1035
    • Davis, M.E.1    Brewster, M.E.2
  • 177
    • 84887231192 scopus 로고    scopus 로고
    • Inactive Pharmaceutical Ingredients
    • FDA
    • FDA, Inactive Pharmaceutical Ingredients (2006).
    • (2006)
  • 178
    • 33750088248 scopus 로고    scopus 로고
    • Guidance for Industry: Nonclinical Studies for the Safety Evaluation of Pharmaceutical Excipients
    • FDA
    • FDA, Guidance for Industry: Nonclinical Studies for the Safety Evaluation of Pharmaceutical Excipients (2005).
    • (2005)


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