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Volumn 36, Issue 1, 1999, Pages 17-28

Highly soluble cyclodextrin derivatives: Chemistry, properties, and trends in development

Author keywords

Analytical methods; Captisol(TM); Commercial aspects; Manufacturing; Molecusol(TM); Quality control; Solubilization; Synthesis; Toxicity; Water soluble CD derivatives

Indexed keywords

CONTROLLED DRUG DELIVERY; DERIVATIVES; DRUG PRODUCTS; SOLUBILITY; SYNTHESIS (CHEMICAL); WATER;

EID: 0033106020     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-409X(98)00092-1     Document Type: Article
Times cited : (497)

References (63)
  • 1
    • 0344537924 scopus 로고    scopus 로고
    • CYCLOLAB Ltd., Budapest
    • CD News database, CYCLOLAB Ltd., Budapest, 1998.
    • (1998) CD News Database
  • 2
    • 0346461917 scopus 로고    scopus 로고
    • Introduction and general overview of cyclodextrin chemistry
    • J. Szejtli, Introduction and general overview of cyclodextrin chemistry, Chem. Rew. 98 (1998) 1743-1753.
    • (1998) Chem. Rew. , vol.98 , pp. 1743-1753
    • Szejtli, J.1
  • 3
    • 0345400290 scopus 로고    scopus 로고
    • Synthesis of β-CD dimers as carrier systems for photodynamic therapy of cancer
    • J. Szejtli, L. Szente (Eds.), Budapest, 1996. March 31-April 2. Kluwer Academic
    • A. Ruebner, Synthesis of β-CD dimers as carrier systems for photodynamic therapy of cancer, in: J. Szejtli, L. Szente (Eds.), Proc. of 8th Int. Symposium on Cyclodextrins, Budapest, 1996. March 31-April 2. Kluwer Academic, 1996, pp. 77-80.
    • (1996) Proc. of 8th Int. Symposium on Cyclodextrins , pp. 77-80
    • Ruebner, A.1
  • 4
    • 0002641462 scopus 로고    scopus 로고
    • Cyclodextrin dimers used to prevent side effects of photochemotherapy
    • J. Szejtli, L. Szente (Eds.), Budapest, March 31-April 2, 1996, Kluwer Academic
    • J.G. Moser, Cyclodextrin dimers used to prevent side effects of photochemotherapy, in: J. Szejtli, L. Szente (Eds.), Proc. of 8th Int. Symposium on Cyclodextrins, Budapest, March 31-April 2, 1996, Kluwer Academic, 1996, pp. 71-76.
    • (1996) Proc. of 8th Int. Symposium on Cyclodextrins , pp. 71-76
    • Moser, J.G.1
  • 5
    • 8244248457 scopus 로고    scopus 로고
    • Cyclodextrins: Their future in drug formations
    • V.J. Stella, R.A. Rajewski, Cyclodextrins: Their future in drug formations, Pharm. Res. 14 (1997) 556-567.
    • (1997) Pharm. Res. , vol.14 , pp. 556-567
    • Stella, V.J.1    Rajewski, R.A.2
  • 6
    • 0031054513 scopus 로고    scopus 로고
    • Pharmaceutical application of cyclodextrins, III. Toxicological issues and safety evaluation
    • T. Irie, K. Uekama, Pharmaceutical application of cyclodextrins, III. Toxicological issues and safety evaluation, J. Pharm. Sci. 86 (1997) 147-162.
    • (1997) J. Pharm. Sci. , vol.86 , pp. 147-162
    • Irie, T.1    Uekama, K.2
  • 7
    • 0004063197 scopus 로고
    • Kluwer Academic, Dordrecht Netherlands
    • J. Szejtli, Cyclodextrin Technology, Kluwer Academic, Dordrecht Netherlands, 1988, p. 450.
    • (1988) Cyclodextrin Technology , pp. 450
    • Szejtli, J.1
  • 8
    • 0029819323 scopus 로고    scopus 로고
    • Pharmaceutical application of cyclodextrins, I. Drug solubilization and stabilization
    • T. Loftsson, M. Brewster, Pharmaceutical application of cyclodextrins, I. Drug solubilization and stabilization, J. Pharm. Sci. 85 (1996) 1017-1025.
    • (1996) J. Pharm. Sci. , vol.85 , pp. 1017-1025
    • Loftsson, T.1    Brewster, M.2
  • 9
    • 0344106429 scopus 로고    scopus 로고
    • Wacker Werk + Wirken, 1998 1, 21-25
    • Wacker Werk + Wirken, 1998 1, 21-25.
  • 12
    • 0000046235 scopus 로고
    • Cyclodextrin polymers in the pharmaceutical industry
    • E. Fenyvesi, Cyclodextrin polymers in the pharmaceutical industry, J. Incl. Phenom. 6 (1988) 537-545.
    • (1988) J. Incl. Phenom. , vol.6 , pp. 537-545
    • Fenyvesi, E.1
  • 13
    • 0344537923 scopus 로고    scopus 로고
    • Cyclodextrin derivatives with enhanced solubility power and lower toxicity
    • Santiago de Compostela
    • J. Pitha, Cyclodextrin derivatives with enhanced solubility power and lower toxicity, Proc. of 9th Int. Symposium on Cyclodextrins, Santiago de Compostela, 1998.
    • (1998) Proc. of 9th Int. Symposium on Cyclodextrins
    • Pitha, J.1
  • 14
    • 0025714175 scopus 로고
    • Distribution of substituents in 2-hydroxypropyl ethers of cyclomaltoheptaose
    • J. Pitha, T.C. Rao, Distribution of substituents in 2-hydroxypropyl ethers of cyclomaltoheptaose, Carbohydr. Res. 200 (1990) 429-435.
    • (1990) Carbohydr. Res. , vol.200 , pp. 429-435
    • Pitha, J.1    Rao, T.C.2
  • 15
    • 0026343205 scopus 로고
    • Crystal structure of 2-O[(s)-2-hydroxypropyl]-cyclomaltoheptaose
    • K. Harata, J. Pitha, T. Rao, K. Fukunaga, K. Uekama, Crystal structure of 2-O[(s)-2-hydroxypropyl]-cyclomaltoheptaose, Carbohydr. Res. 22 (1991) 37-45.
    • (1991) Carbohydr. Res. , vol.22 , pp. 37-45
    • Harata, K.1    Pitha, J.2    Rao, T.3    Fukunaga, K.4    Uekama, K.5
  • 16
    • 49949124433 scopus 로고
    • Conformation of O-methylated amylose and cyclodextrins
    • B. Casu, M. Reggiani, G. Vigevani, Conformation of O-methylated amylose and cyclodextrins, Tetrahedron 242 (1967) 803-821.
    • (1967) Tetrahedron , vol.242 , pp. 803-821
    • Casu, B.1    Reggiani, M.2    Vigevani, G.3
  • 17
    • 84987209784 scopus 로고
    • Synthesis of heptakis-(2-O-methyl)-β-cyclodextrin
    • K. Takeo, T. Kuge, Synthesis of heptakis-(2-O-methyl)-β-cyclodextrin, Starch/Starke 287 (1976) 226-227.
    • (1976) Starch/Starke , vol.287 , pp. 226-227
    • Takeo, K.1    Kuge, T.2
  • 18
    • 0026261914 scopus 로고
    • Reactivities of O-2, O-3 and O-6 positions of cycloamyloses in Hakamori methylation
    • T. Rao, J. Pitha, Reactivities of O-2, O-3 and O-6 positions of cycloamyloses in Hakamori methylation, Carbohydr. Res. 200 (1991) 209-213.
    • (1991) Carbohydr. Res. , vol.200 , pp. 209-213
    • Rao, T.1    Pitha, J.2
  • 19
    • 0344968914 scopus 로고
    • Rational design of cyclodextrin derivatives benefits that pay off in applications
    • Anaheim CA
    • M. Aman, H. Reuscher, T. Wimmer, R. Hirsenkorn, Rational design of cyclodextrin derivatives benefits that pay off in applications, 209th ACS National Meeting, Anaheim CA, 1995.
    • (1995) 209th ACS National Meeting
    • Aman, M.1    Reuscher, H.2    Wimmer, T.3    Hirsenkorn, R.4
  • 20
    • 0023446436 scopus 로고
    • Reaction of cyclodextrins with propylene oxide or with glycidol: Analysis of Product Distribution
    • J. Pitha, L. Szabo, H. Fales, Reaction of cyclodextrins with propylene oxide or with glycidol: Analysis of Product Distribution, Carbohydr. Res. 168 (1987) 191-198.
    • (1987) Carbohydr. Res. , vol.168 , pp. 191-198
    • Pitha, J.1    Szabo, L.2    Fales, H.3
  • 21
    • 0344537921 scopus 로고    scopus 로고
    • Cyclolab, Budapest
    • J. Szejtli (Ed.), Cyclodextrin News, Vol. 11. No. 2. Cyclolab, Budapest, 1997.
    • (1997) Cyclodextrin News , vol.11 , Issue.2
    • Szejtli, J.1
  • 23
    • 0344106427 scopus 로고
    • Univ. Kansas assignee derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use of there of WO. 9111172. A1, 8. Aug
    • V.J. Stella, R.A. Rajewski, Univ. Kansas assignee derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use of there of WO. 9111172. A1, 8. Aug, 1991.
    • (1991)
    • Stella, V.J.1    Rajewski, R.A.2
  • 24
    • 0344106423 scopus 로고    scopus 로고
    • Published by CyDex
    • J. Kiesle (Ed.), Cyclopedia, 1 (2) (1998) 2-4. Published by CyDex.
    • (1998) Cyclopedia , vol.1 , Issue.2 , pp. 2-4
    • Kiesle, J.1
  • 25
    • 0024593040 scopus 로고
    • Control of angiogenesis with synthetic heparin substitutes
    • J. Folkman, P. Weisz, M. Joullie, Control of angiogenesis with synthetic heparin substitutes, Science 243 (1989) 1490-1493.
    • (1989) Science , vol.243 , pp. 1490-1493
    • Folkman, J.1    Weisz, P.2    Joullie, M.3
  • 26
    • 0345400285 scopus 로고
    • Cycloamylose sulfates and derivatives thereof US Patent, 2 923 704
    • L. Berger, J. Lee, Cycloamylose sulfates and derivatives thereof US Patent, 2 923 704, 1960.
    • (1960)
    • Berger, L.1    Lee, J.2
  • 27
    • 0343949656 scopus 로고
    • Sulfated sugar α-CD-sulfate an uniquely potent anti HIV agent
    • R. Anand, S. Nyyan, J. Pitha, Sulfated sugar α-CD-sulfate an uniquely potent anti HIV agent, Antiviral Chem. 1 (1990) 41-46.
    • (1990) Antiviral Chem. , vol.1 , pp. 41-46
    • Anand, R.1    Nyyan, S.2    Pitha, J.3
  • 28
    • 0025822934 scopus 로고
    • Cyclodextrin sulfates: Characterization as polydisperse and amorphous mixtures
    • J. Pitha, L. Mallis, D. Lamb, T. Irie, K. Uekama, Cyclodextrin sulfates: Characterization as polydisperse and amorphous mixtures, Pharm. Res. 8 (1991) 1151-1154.
    • (1991) Pharm. Res. , vol.8 , pp. 1151-1154
    • Pitha, J.1    Mallis, L.2    Lamb, D.3    Irie, T.4    Uekama, K.5
  • 29
    • 0029028396 scopus 로고
    • Cyclodextrin sulfates in parenteral use: Protection against gentamicin nephrotoxicity in the rat
    • K. Shiotani, T. Irie, K. Uekama, Y. Ishimaru, Cyclodextrin sulfates in parenteral use: Protection against gentamicin nephrotoxicity in the rat, Eur. J. Pharm. Sci. 3 (1995) 139-151.
    • (1995) Eur. J. Pharm. Sci. , vol.3 , pp. 139-151
    • Shiotani, K.1    Irie, T.2    Uekama, K.3    Ishimaru, Y.4
  • 31
    • 0021955115 scopus 로고
    • Pharmaceutical application of methylated cyclodextrins
    • K. Uekama, Pharmaceutical application of methylated cyclodextrins, Pharm. Int. 6 (1985) 61-65.
    • (1985) Pharm. Int. , vol.6 , pp. 61-65
    • Uekama, K.1
  • 32
    • 33745048423 scopus 로고
    • Aggregation of cyclodextrins: An explanation of the abnormal solubility of β-cyclodextrin
    • A.W. Coleman, I. Nicholis, N. Keller, J. Dalbiez, Aggregation of cyclodextrins: An explanation of the abnormal solubility of β-cyclodextrin, J. Incl. Phen. Mol. Recogn. 13 (1992) 139-143.
    • (1992) J. Incl. Phen. Mol. Recogn. , vol.13 , pp. 139-143
    • Coleman, A.W.1    Nicholis, I.2    Keller, N.3    Dalbiez, J.4
  • 33
    • 0031808232 scopus 로고    scopus 로고
    • Spontaneous opalescence of aqueous γ-CD solutions: Complex formation or self-aggregation?
    • L. Szente, J. Szejtli, G. Kis, Spontaneous opalescence of aqueous γ-CD solutions: Complex formation or self-aggregation?, J. Pharm. Sci. 87 (1998) 778-781.
    • (1998) J. Pharm. Sci. , vol.87 , pp. 778-781
    • Szente, L.1    Szejtli, J.2    Kis, G.3
  • 34
    • 0344537917 scopus 로고    scopus 로고
    • Highly soluble multicomponent complexes containing base type drug an acid and cyclodextrin PCT Patent Appl. WO 94116733
    • P. Chiesi, P. Ventura, M. Pasini, E. Redenti, J. Szejtli M. Vikmon, Highly soluble multicomponent complexes containing base type drug an acid and cyclodextrin PCT Patent Appl. WO 94116733.
    • Chiesi, P.1    Ventura, P.2    Pasini, M.3    Redenti, E.4    Szejtli, J.5    Vikmon, M.6
  • 35
    • 0011962656 scopus 로고    scopus 로고
    • Pharmacokinetic study of orally administered ketoconazole and its multicomponent complex in rabbits with normal and low gastric acidity
    • J. Szejtli, L. Szente (Eds.), Kluwer Academic
    • A. Gerlóczy, Pharmacokinetic study of orally administered ketoconazole and its multicomponent complex in rabbits with normal and low gastric acidity, in: J. Szejtli, L. Szente (Eds.), Proc. 3rd Int. Sump, on Cyclodextrins, 1996, Kluwer Academic, pp. 515-518.
    • (1996) Proc. 3rd Int. Sump, on Cyclodextrins , pp. 515-518
    • Gerlóczy, A.1
  • 36
    • 0011947276 scopus 로고
    • Solution for insolubility problems of base type drugs: Multicomponent cyclodextrin complexation
    • Budapest, 9-11 May
    • L. Szente, J. Szejtli, M. Vikmon, et al., Solution for insolubility problems of base type drugs: Multicomponent cyclodextrin complexation, Proc. 1st World Meeting APGI/ APV, Budapest, 9-11 May, 1995, pp. 579-580.
    • (1995) Proc. 1st World Meeting APGI/ APV , pp. 579-580
    • Szente, L.1    Szejtli, J.2    Vikmon, M.3
  • 37
    • 0021810514 scopus 로고
    • Amorphous water-soluble derivatives of cyclodextrins. Non-toxic dissolution enhancing excipients
    • J. Pitha, J. Pitha, Amorphous water-soluble derivatives of cyclodextrins. Non-toxic dissolution enhancing excipients, J. Pharm. Sci. 94 (1985) 987-990.
    • (1985) J. Pharm. Sci. , vol.94 , pp. 987-990
    • Pitha, J.1    Pitha, J.2
  • 39
    • 0023600048 scopus 로고
    • Amorphous water-soluble derivatives of cyclodextrins: From test tube to patient
    • J. Pitha, Amorphous water-soluble derivatives of cyclodextrins: from test tube to patient, J. Contr. Release 6 (1987) 309-313.
    • (1987) J. Contr. Release , vol.6 , pp. 309-313
    • Pitha, J.1
  • 40
    • 0022965044 scopus 로고
    • Cyclodextrin ethers as solubilizers; Enzymatic degradation
    • B.W. Muller, U. Brauns, Cyclodextrin ethers as solubilizers; Enzymatic degradation, Pharm. Ind. 48 (1986) 1427-1429.
    • (1986) Pharm. Ind. , vol.48 , pp. 1427-1429
    • Muller, B.W.1    Brauns, U.2
  • 41
    • 0031588728 scopus 로고    scopus 로고
    • Ruggedness of enantiomeric separation by capillary electrophoresis and HPLC with methylated cyclodextrins as chiral selectors
    • J. Szemán, N. Roos, K. Csabai, Ruggedness of enantiomeric separation by capillary electrophoresis and HPLC with methylated cyclodextrins as chiral selectors, J. Chromatogr. 763 (1997) 139-147.
    • (1997) J. Chromatogr. , vol.763 , pp. 139-147
    • Szemán, J.1    Roos, N.2    Csabai, K.3
  • 42
    • 0025161725 scopus 로고
    • Pharmaceutical usefulness of HPBCD, "E Pluribus unum" Is an essential feature
    • T. Rao, H. Fales, J. Pitha, Pharmaceutical usefulness of HPBCD, "E Pluribus unum" Is an essential feature, Pharm. Res. 7 (1990) 612-615.
    • (1990) Pharm. Res. , vol.7 , pp. 612-615
    • Rao, T.1    Fales, H.2    Pitha, J.3
  • 44
    • 0018875104 scopus 로고
    • Application of californium 252 plasma-desorption mass spectroscopy in the analysis of cyclodextrins and their derivatives Proc
    • J.E. Hunt, D. Macfarlaine, I. Katz, R. Dougherty, Application of californium 252 plasma-desorption mass spectroscopy in the analysis of cyclodextrins and their derivatives Proc, Natl. Acad. Sci. USA. 77 (1980) 1745-1748.
    • (1980) Natl. Acad. Sci. USA. , vol.77 , pp. 1745-1748
    • Hunt, J.E.1    Macfarlaine, D.2    Katz, I.3    Dougherty, R.4
  • 45
    • 0011898657 scopus 로고
    • Laser-assisted field desorption maa spectrometry part. IV.: Laser assisted filed desorption MS of cyclomaltohexaose and heptaose
    • H.R. Schulten, T. Komori, K. Fujita, A. Shouda, Laser-assisted field desorption maa spectrometry part. IV.: laser assisted filed desorption MS of cyclomaltohexaose and heptaose, Carbohydr. Res. 107 (1982) 177-186.
    • (1982) Carbohydr. Res. , vol.107 , pp. 177-186
    • Schulten, H.R.1    Komori, T.2    Fujita, K.3    Shouda, A.4
  • 46
    • 0001002989 scopus 로고
    • Purification and analysis of cyclodextrin derivatives
    • A. Deege, H. Husman, K. Huebinger, Purification and analysis of cyclodextrin derivatives, J. High Resol. Chromat. 16 (1993) 587-589.
    • (1993) J. High Resol. Chromat. , vol.16 , pp. 587-589
    • Deege, A.1    Husman, H.2    Huebinger, K.3
  • 47
    • 0022592084 scopus 로고
    • Hydroxypropyl-β-cyclodextrin: Preparation and characterization, Effects on solubility of drugs
    • J. Pitha, J. Milecki, H. Fales, K. Uekama, Hydroxypropyl-β-cyclodextrin: preparation and characterization, Effects on solubility of drugs, Int. J. Pharm. 29 (1986) 73-82.
    • (1986) Int. J. Pharm. , vol.29 , pp. 73-82
    • Pitha, J.1    Milecki, J.2    Fales, H.3    Uekama, K.4
  • 48
    • 0025714175 scopus 로고
    • Distribution of substituents in 2-hydroxypropyl-ethers of cyclomaltoheptaose
    • J. Pitha, T. Rao, Distribution of substituents in 2-hydroxypropyl-ethers of cyclomaltoheptaose, Carbohydr. Res. 200 (1990) 429-435.
    • (1990) Carbohydr. Res. , vol.200 , pp. 429-435
    • Pitha, J.1    Rao, T.2
  • 49
    • 0029157211 scopus 로고
    • Separation of cyclodextrins and derivatives by TLC and preparative column chromatography
    • J. Jindrich, J. Pitha, B. Lindberg, Separation of cyclodextrins and derivatives by TLC and preparative column chromatography, Carbohydr. Res. 275 (1995) 1-7.
    • (1995) Carbohydr. Res. , vol.275 , pp. 1-7
    • Jindrich, J.1    Pitha, J.2    Lindberg, B.3
  • 50
    • 0029633812 scopus 로고
    • Regioselectivity of alkylation of cyclomaltoheptaose and synthesis of its mono-2-O-methyl, -ethyl, -allyl, and propyl-derivatives
    • J. Jindrich, J. Pitha, B. Lindberg, P. Seffers, K. Harata, Regioselectivity of alkylation of cyclomaltoheptaose and synthesis of its mono-2-O-methyl, -ethyl, -allyl, and propyl-derivatives, Carbohydr. Res. 266 (1995) 75-80.
    • (1995) Carbohydr. Res. , vol.266 , pp. 75-80
    • Jindrich, J.1    Pitha, J.2    Lindberg, B.3    Seffers, P.4    Harata, K.5
  • 51
    • 0027413851 scopus 로고
    • Liquid chromatographic determination of β-cyclodextrin derivatives based on fluorescence enhancement after inclusion complex formation
    • H.J.E.M. Reeuwijk, H. Irth, U.R. Tjaden, F.W.H.M. Merkus, J. van der Greef, Liquid chromatographic determination of β-cyclodextrin derivatives based on fluorescence enhancement after inclusion complex formation, J. Chromatogr. Biomed. Appl. 614 (1993) 95-101.
    • (1993) J. Chromatogr. Biomed. Appl. , vol.614 , pp. 95-101
    • Reeuwijk, H.J.E.M.1    Irth, H.2    Tjaden, U.R.3    Merkus, F.W.H.M.4    Van Der Greef, J.5
  • 52
    • 0027337758 scopus 로고
    • Microanalyses of β-cyclodextrin and glucosyl-β-cyclodextrin in biological matrices by HPLC with pulsed amperometric detection
    • M. Fukuda, Y. Kubota, A. Ikuta, K. Hasegawa, K. Koizumi, Microanalyses of β-cyclodextrin and glucosyl-β-cyclodextrin in biological matrices by HPLC with pulsed amperometric detection, Anal. Biochem. 212 (1993) 289-291.
    • (1993) Anal. Biochem. , vol.212 , pp. 289-291
    • Fukuda, M.1    Kubota, Y.2    Ikuta, A.3    Hasegawa, K.4    Koizumi, K.5
  • 53
    • 0027201533 scopus 로고
    • Quantification of trace levels of β-cyclodextrin and substitution pattern in hydroxypropyl-β-cyclodextrin using HPLC with polarimetric detection
    • L.G. Goodall, D.M. Loran, S. John, Quantification of trace levels of β-cyclodextrin and substitution pattern in hydroxypropyl-β-cyclodextrin using HPLC with polarimetric detection, Chirality 5 (1993) 220-223.
    • (1993) Chirality , vol.5 , pp. 220-223
    • Goodall, L.G.1    Loran, D.M.2    John, S.3
  • 54
    • 0013505446 scopus 로고
    • Determination of hydroxypropyl-β-cyclodextrin in plasma and urine by size exclusion chromatography with post column detection
    • O. Huber, J. Szejtli (Eds.), Kluwer, Dordrecht, Netherlands
    • S.C. Szathmary, Determination of hydroxypropyl-β-cyclodextrin in plasma and urine by size exclusion chromatography with post column detection, in: O. Huber, J. Szejtli (Eds.), Proc. Int. Symp. Cyclodextrins, 4th ed., Kluwer, Dordrecht, Netherlands, 1988, pp. 427-433.
    • (1988) Proc. Int. Symp. Cyclodextrins, 4th Ed. , pp. 427-433
    • Szathmary, S.C.1
  • 55
    • 0344537914 scopus 로고
    • Characterization of cyclodextrin derivatives by chemical degradation
    • Detmold, Germany, April 25-27
    • P. Mischnick, Characterization of cyclodextrin derivatives by chemical degradation, The 41st Starch Convention, Detmold, Germany, April 25-27, 1990.
    • (1990) The 41st Starch Convention
    • Mischnick, P.1
  • 56
    • 0344537913 scopus 로고
    • Determination of the pattern of substitution of hydroxyethyl- And hydroxypropyl-cyclomaltoheptaoses
    • P. Mischnick-Luebecke, Determination of the pattern of substitution of hydroxyethyl- and hydroxypropyl-cyclomaltoheptaoses Carbohydr. Res., (1989) 187-197.
    • (1989) Carbohydr. Res. , pp. 187-197
    • Mischnick-Luebecke, P.1
  • 57
    • 0022998896 scopus 로고
    • Analysis of heptakis 2,6,-di-O-methyl-β-cyclodextrin by thin-layer chromatography, HPLC and gas chromatography/mass spectrometry
    • K. Koizumi, Y. Kubota, T. Utamura, S. Horiyama, Analysis of heptakis 2,6,-di-O-methyl-β-cyclodextrin by thin-layer chromatography, HPLC and gas chromatography/mass spectrometry, J. Chromatogr. 368 (1986) 329-337.
    • (1986) J. Chromatogr. , vol.368 , pp. 329-337
    • Koizumi, K.1    Kubota, Y.2    Utamura, T.3    Horiyama, S.4
  • 58
    • 0027222036 scopus 로고
    • Electrospray mass spectroscopy of neutral and acidic oligosaccharides, methylated cyclodextrins and unknown derivatives from fruit material
    • A.P. Tinke, R.A.M. van der Hoeven, W.M.A. Niessen, J. van der Greef, J.-P. Vincken, H.A. Schols, Electrospray mass spectroscopy of neutral and acidic oligosaccharides, methylated cyclodextrins and unknown derivatives from fruit material, J. Chromatogr. 647 (1993) 279-287.
    • (1993) J. Chromatogr. , vol.647 , pp. 279-287
    • Tinke, A.P.1    Van Der Hoeven, R.A.M.2    Niessen, W.M.A.3    Van Der Greef, J.4    Vincken, J.-P.5    Schols, H.A.6
  • 59
    • 0024805188 scopus 로고
    • Analysis of cyclodextrins using FAB/MS and tandem mass spectrometry
    • R.D. Voyksner, Analysis of cyclodextrins using FAB/MS and tandem mass spectrometry, Biomed. Environ. Mass Spectrom. 18 (1989) 1071-1078.
    • (1989) Biomed. Environ. Mass Spectrom. , vol.18 , pp. 1071-1078
    • Voyksner, R.D.1
  • 60
    • 0344968910 scopus 로고    scopus 로고
    • Characterization of sulfobutylether β-cyclodextrin mixtures
    • J. Szejtli, L. Szente (Eds.), Budapest, Kluwer Academic, Dordrecht, Holland
    • E.A. Luna, E.R. Bronancini, D.O. Thompson, R.A. Rajewski, V.J. Stella, Characterization of sulfobutylether β-cyclodextrin mixtures, in: J. Szejtli, L. Szente (Eds.), Proc. Intl. Symp. on Cyclodextrins, Budapest, Kluwer Academic, Dordrecht, Holland, 1996, pp. 133-136.
    • (1996) Proc. Intl. Symp. on Cyclodextrins , pp. 133-136
    • Luna, E.A.1    Bronancini, E.R.2    Thompson, D.O.3    Rajewski, R.A.4    Stella, V.J.5
  • 61
    • 0030596480 scopus 로고    scopus 로고
    • Analysis of charged cyclodextrin derivatives by ion-spray, matrix-assisted-laser-desorption, fast-atom-bombardment mass-spectroscopy and capillary electrophoresis
    • B. Chankvetadze, G. Endresz, Analysis of charged cyclodextrin derivatives by ion-spray, matrix-assisted-laser-desorption, fast-atom-bombardment mass-spectroscopy and capillary electrophoresis, Carohydr. Res. 287 (1996) 139-155.
    • (1996) Carohydr. Res. , vol.287 , pp. 139-155
    • Chankvetadze, B.1    Endresz, G.2
  • 62
    • 0031042310 scopus 로고    scopus 로고
    • Cyclodextrins-enabling excipients: Their present and future use in pharmaceuticals
    • D.O. Thompson, Cyclodextrins-enabling excipients: Their present and future use in pharmaceuticals, Crit. Rev. in Ther. Drug Carrier Systems. 14 (1997) 1-104.
    • (1997) Crit. Rev. in Ther. Drug Carrier Systems. , vol.14 , pp. 1-104
    • Thompson, D.O.1
  • 63
    • 0004039575 scopus 로고
    • American Pharmaceutical Association, Washington, ISBN in the USA 091730668
    • A. Wade, P.J. Weller (Eds.), Handbook of Pharmaceutical Excipients, 2nd ed., American Pharmaceutical Association, Washington, ISBN in the USA 091730668, 1994, pp. 145-148.
    • (1994) Handbook of Pharmaceutical Excipients, 2nd Ed. , pp. 145-148
    • Wade, A.1    Weller, P.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.