Accumulation of Werner protein at DNA double-strand breaks in human cells

Journal of Cell Science

Volumn 118, Issue 18, 2005, Pages 4153-4162

  Lan, Li ^a   Nakajima, Satoshi ^a   Komatsu, Kenshi ^b   Nussenzweig, Andre ^c   Shimamoto, Akira ^d   Oshima, Junko ^e   Yasui, Akira ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c NATIONAL CANCER INSTITUTE   (United States)

^d GeneCare Research Institute   (Japan)

^e UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Damage accumulation; Double strand breaks; HRDC domain; Laser irradiation; Werner protein

Indexed keywords

DNA DEPENDENT PROTEIN KINASE; DNA DIRECTED DNA POLYMERASE BETA; DOUBLE STRANDED DNA; EXONUCLEASE; HELICASE; HISTONE H2A; HISTONE H2AX; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; RECQ HELICASE; RIBONUCLEASE III; SINGLE STRANDED DNA; UNCLASSIFIED DRUG; WERNER SYNDROME PROTEIN;

ARTICLE; AUTOSOMAL RECESSIVE DISORDER; CARBOXY TERMINAL SEQUENCE; CELL NUCLEUS; CONTROLLED STUDY; DNA REPAIR; DNA STRAND BREAKAGE; ENZYME ACTIVITY; GENE DELETION; HUMAN; HUMAN CELL; IN VITRO STUDY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; WERNER SYNDROME;

ANIMALS; CELL LINE; DNA; DNA DAMAGE; DNA HELICASES; GREEN FLUORESCENT PROTEINS; HELA CELLS; HUMANS; KINETICS; MICE; MICROSCOPY, CONFOCAL; PHOTOSENSITIZING AGENTS; PYRROLIDINES; QUINOLIZINES; RECQ HELICASES;

EID: 27144551710     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.02544     Document Type: Article

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