Delayed administration of zingerone mitigates the behavioral and histological alteration via repression of oxidative stress and intrinsic programmed cell death in focal transient ischemic rats

Pharmacology Biochemistry and Behavior

Volumn 113, Issue , 2013, Pages 53-62

  Vaibhav, Kumar ^a,d   Shrivastava, Pallavi ^a,e   Tabassum, Rizwana ^a   Khan, Andleeb ^a,c   Javed, Hayate ^a,f   Ahmed, Md Ejaz ^a   Islam, Farah ^b,c   Safhi, Mohammed M ^c   Islam, Fakhrul ^a,c  

^a HAMDARD UNIVERSITY   (India)

^b HAMDARD UNIVERSITY   (India)

^c JAZAN UNIVERSITY   (Saudi Arabia)

^d UNIVERSITY OF DELHI   (India)

^e UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY   (United States)

^f UNIVERSITY OF IOWA HOSPITALS AND CLINICS   (United States)

Author keywords

Apaf 1; Bax; Bcl 2; Behavior; Caspase; Ischemia reperfusion

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CASPASE 3; CASPASE 9; GLUTATHIONE; PROTEIN BAX; PROTEIN BCL 2; SUPEROXIDE DISMUTASE; ZINGERONE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BRAIN INFARCTION SIZE; BRAIN NERVE CELL; COMPETITIVE INHIBITION; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXTERNAL CAROTID ARTERY; GINGER; GRIP STRENGTH; HISTOPATHOLOGY; INTERNAL CAROTID ARTERY; LIPID PEROXIDATION; MALE; MIDDLE CEREBRAL ARTERY; MIDDLE CEREBRAL ARTERY OCCLUSION; MOTOR COORDINATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; TRANSIENT ISCHEMIC ATTACK;

RATTUS; ZINGIBER OFFICINALE;

2,2-DIPHENYL-1-PICRYLHYDRAZYL; 2,3,5-TRIPHENYLTETRAZOLIUM CHLORIDE; 5,5′-DITHIOBIS-2-NITROBENZOIC ACID; 6-HYDROXYDOPAMINE; 6-OHDA; ADENOSINE TRIPHOSPHATE; ANALYSIS OF VARIANCE; ANOVA; APAF-1; APOPTOTIC PROTEASE ACTIVATING FACTOR-1; ATP; B-CELL LYMPHOMA-2; B.WT; BAX; BCL-2; BCL-2 ASSOCIATED X PROTEIN; BEHAVIOR; BODY WEIGHT; BOVINE SERUM ALBUMIN; BSA; CASPASE; CBF; CEREBRAL BLOOD FLOW; CRESYL VIOLET; CV; CYSTEINE-ASPARTIC PROTEASES; DPPH; DTNB; ECA; EDTA; ETHYLENE DIAMINE TETRA-ACETIC ACID; EXTERNAL CAROTID ARTERY; FLEXION TEST; FT; GSH; H & E; HEMATOXYLIN AND EOSIN; I/R; ICA; INORGANIC PHOSPHATE; INTERNAL CAROTID ARTERY; INTRINSIC PROGRAMMED CELL DEATH; IPCD; ISCHEMIA-REPERFUSION; LIPID PEROXIDATION; LPO; MCA; MCAO; MIDDLE CEREBRAL ARTERY; MIDDLE CEREBRAL ARTERY OCCLUSION; PBS; PHOSPHATE BUFFER SALINE; PI; PMS; POST MITOCHONDRIAL SUPERNATANT; REACTIVE OXYGEN SPECIES; REDUCED GLUTATHIONE; ROS; S-1; SMA; SOD; SPONTANEOUS MOTOR ACTIVITY; SUPERNATANT-1; SUPEROXIDE DISMUTASE; TBA; TBARS; TCA; THIOBARBITURIC ACID; THIOBARBITURIC REACTIVE SUBSTANCES; TRICHLOROACETIC ACID; TTC;

ANIMALS; APOPTOSIS; BEHAVIOR, ANIMAL; BRAIN ISCHEMIA; ENZYME-LINKED IMMUNOSORBENT ASSAY; GUAIACOL; MALE; OXIDATIVE STRESS; RATS; RATS, WISTAR;

EID: 84887111649     PISSN: 00913057     EISSN: 18735177     Source Type: Journal    
DOI: 10.1016/j.pbb.2013.10.008     Document Type: Article

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