A two-hour window for hypothermic modulation of early events that impact delayed opening of the rat blood-brain barrier after ischemia

Acta Neuropathologica

Volumn 108, Issue 5, 2004, Pages 406-412

  Preston, Edward ^a   Webster, Jacqueline ^a  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

Blood brain barrier; Hypothermia; Ischemia; Stroke; Vasogenic edema

Indexed keywords

CYCLOSPORIN A; MINOCYCLINE; MITOCHONDRIAL ENZYME; SUCCINATE DEHYDROGENASE; SUCROSE;

ANESTHESIA INDUCTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD BRAIN BARRIER; BODY TEMPERATURE; BRAIN EDEMA; BRAIN INJURY; BRAIN ISCHEMIA; CAROTID ARTERY OBSTRUCTION; CELL ASSAY; CONTROLLED STUDY; ENZYME ACTIVITY; HYPOTENSION; INDUCED HYPOTHERMIA; MALE; NEUROPROTECTION; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; REPERFUSION; TISSUE INJURY;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BLOOD-BRAIN BARRIER; BRAIN EDEMA; BRAIN ISCHEMIA; DISEASE MODELS, ANIMAL; HYPOTHERMIA, INDUCED; MALE; MITOCHONDRIA; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; TIME FACTORS;

EID: 7744223842     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00401-004-0905-4     Document Type: Article

References (23)

1. Busto R, Dietrich WD, Globus MY, Ginsberg MD (1989) Postischemic hypothermia inhibits CA1 hippocampal ischemic neuronal injury. Neurosci Lett 101:299-304. 10.1016/0304-3940(89)90549-1, 1:STN:280:BiaA28rotFA%3D, 2771174
2. Coimbra C, Wieloch T (1994) Moderate hypothermia mitigates neuronal damage in the rat brain when initiated several hours following transient cerebral ischemia. Acta Neuropathol 87:325-331. 10.1007/s004010050093, 1:STN:280:ByuB1cjnslI%3D, 8017166
3. Corbett D, Hamilton M, Colbourne F (2000) Persistent neuroprotection with prolonged postischemic hypothermia in adult rats subjected to transient middle cerebral artery occlusion. Exp Neurol 163:200-206. 10.1006/exnr.2000.7369, 1:STN:280:DC%2BD3c3kvFSqsg%3D%3D, 10785459
4. Hsu CY, Lui TH, Xu J, Hogan EL, Chao J (1990) Lipid inflammatory mediators in ischemic brain edema and injury. In: Bazan NG (ed) Lipid mediators in ischemic brain damage and experimental epilepsy, new trends in lipid mediators research, vol 4. Karger, Basel, pp 85-112
5. Huang ZG, Xue D, Preston E, Karbalai H, Buchan AM (1999) Biphasic opening of the blood-brain barrier following transient focal ischemia: effects of hypothermia. Can J Neurol Sci 16:298-304
6. Huh PW, Belayev L, Zhao W, Koch S, Busto R, Ginsberg MD (2000) Comparative neuroprotective efficacy of prolonged moderate intraischemic and postischemic hypothermia in focal cerebral ischemia. J Neurosurg 92:91-99. 1:STN:280:DC%2BD3c%2FotFygsQ%3D%3D, 10616087
7. Kuroda S, Janelidze S, Siesjo BK (1999) The immunosuppressants cyclosporin A and FK506 equally ameliorate brain damage due to 30-min middle cerebral artery occlusion in hyperglycemic rats. Brain Res 835:148-153. 10.1016/S0006-8993(99)01535-8, 1:CAS:528:DyaK1MXktlyitb0%3D, 1041536
8. Mizuta K, Ohmori M, Miyashita F, Kitoh Y, Fujimura A, Mori M, Kanno T, Hashizume K, Kobayashi E (1999) Effect of pretreatment with FTY720 and cyclosporin on ischaemia-reperfusion injury of the liver in rats. J Pharm Pharmacol 51:1423-1428. 10.1211/0022357991777065, 1:CAS:528:DC%2BD3cXhtFCjs70%3D, 10678498
9. Ohno K, Pettigrew KD, Rapoport SI (1978) Lower limits of cerebrovascular permeability to nonelectrolytes in the conscious rat. Am J Physiol 235:H299-H307. 1:CAS:528:DyaE1cXmtFals7s%3D, 696840
10. Preston E, Webster J (2000) Spectrophotometric measurement of experimental brain injury. J Neurosci Methods 94:187-192. 10.1016/S0165-0270(99)00146-6, 1:CAS:528:DyaK1MXnvFentLs%3D, 10661838
11. 3 H]inulin across rat blood-brain barrier after cerebral ischemia. Acta Neuropathol 103:237-242. 10.1007/s004010100458, 1:CAS:528:DC%2BD38XhtF2itb0%3D, 11907803
12. Preston E, Allen M, Haas N (1983). A modified method for measurement of radiotracer permeation across the rat blood brain barrier: The problem of correcting brain uptake for intravascular tracer. J Neurosci Methods 9:45-55. 10.1016/0165-0270(83)90108-5, 1:STN:280:BiuD3sfhtFE%3D, 6415348
13. 3 H]sucrose following forebrain ischemia in the rat. Acta Neurochir (Wien) S51:174-176
14. Preston E, Sutherland G, Finsten A (1993) Three openings of the blood-brain barrier produced by forebrain ischemia in the rat. Neurosci Lett 149:75-78. 10.1016/0304-3940(93)90351-K, 1:STN:280:ByyB38nhs10%3D, 8469386
15. Siesjo BK, Siesjo P (1996) Mechanisms of secondary brain injury. Eur J Anaesthesiol 13:247-268. 10.1046/j.1365-2346.1996.00976.x, 1:STN:280:BymA2cnnvFw%3D, 8737117
16. Smith ML, Auer RN, Siesjo BK (1984) The density and distribution of ischemic brain injury in the rat following 2-10 min forebrain ischemia. Acta Neuropathol (Berl) 64:319-332
17. Sullivan PG, Thompson M, Scheff SW (2000) Continuous infusion of cyclosporin A postinjury significantly ameliorates cortical damage following traumatic brain injury. Exp Neurol 161:631-637. 10.1006/exnr.1999.7282, 1:CAS:528:DC%2BD3cXht1OntLs%3D, 10686082
18. Sutcliffe IT, Smith HA, Stanimirovic D, Hutchison JS (2001) Effects of moderate hypothermia on IL-1 beta-induced leukocyte rolling and adhesion in pial microcirculation of mice and on proinflammatory gene expression in human cerebral endothelial cells. J Cereb Blood Flow Metab 21:1310-1319. 10.1097/00004647-200111000-00007, 1:CAS:528:DC%2BD3MXpt1Wkur0%3D, 11702046
19. Thornhill J, Corbett D (2001) Therapeutic implications of hypothermic and hyperthermic temperature conditions in stroke patients. Can J Physiol Pharmacol 79:254-261. 10.1139/cjpp-79-3-254, 1:CAS:528:DC%2BD3MXitlWjsLY%3D, 11294602
20. Uchino H, Elmer E, Uchino K, Lindvall O, Siesjo BK (1995) Cyclosporin A dramatically ameliorates CA1 hippocampal damage following transient forebrain ischaemia in the rat. Acta Physiol Scand 155:469-471. 1:CAS:528:DyaK28XitFCgtw%3D%3D, 8719269
21. Wang CX, Yang T, Shuaib A (2003) Effects of minocycline alone and in combination with mild hypothermia in embolic stroke. Brain Res 963:327-329. 10.1016/S0006-8993(02)04045-3, 1:CAS:528:DC%2BD3sXmsV2nsw%3D%3D, 12560140
22. Xue D, Huang ZG, Smith KE, Buchan AM (1992) Immediate or delayed mild hypothermia prevent focal cerebral infarction. Brain Res 587:66-72. 10.1016/0006-8993(92)91428-H, 1:STN:280:By2H3cvovF0%3D, 1525650
23. Yrjänheikki J, Tikka T, Keinänen R, Goldsteins G, Chan PH, Koistinaho J (1999) A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window. Proc Natl Acad Sci USA 96:13496-13500. 10.1073/pnas.96.23.13496, 10557349