메뉴 건너뛰기




Volumn 8, Issue 1, 1998, Pages 49-62

Differential regulation of Bax, Bcl-2, and Bcl-X proteins in focal cortical ischemia in the rat

Author keywords

[No Author keywords available]

Indexed keywords

DNA FRAGMENT; PROTEIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL X; UNCLASSIFIED DRUG;

EID: 0031983648     PISSN: 10156305     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1750-3639.1998.tb00134.x     Document Type: Article
Times cited : (138)

References (63)
  • 1
    • 0027243086 scopus 로고
    • The proto-oncogene bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis
    • Allsopp TE, Wyatt S, Paterson HF, Davies AM (1993) The proto-oncogene bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis. Cell 73: 295-307
    • (1993) Cell , vol.73 , pp. 295-307
    • Allsopp, T.E.1    Wyatt, S.2    Paterson, H.F.3    Davies, A.M.4
  • 2
    • 0027523461 scopus 로고
    • Apoptosis induced by withdrawal of interleukin-3 (IL-3) from an IL-3-dependent hematopoietic cell line is associated with repartitioning of intracellular calcium and is blocked by enforced Bcl-2 oncoprotein production
    • Baffy G, Miyashita T, Williamson JR, Reed JC (1993) Apoptosis induced by withdrawal of interleukin-3 (IL-3) from an IL-3-dependent hematopoietic cell line is associated with repartitioning of intracellular calcium and is blocked by enforced Bcl-2 oncoprotein production. J Biol Chem 268: 6511-6519
    • (1993) J Biol Chem , vol.268 , pp. 6511-6519
    • Baffy, G.1    Miyashita, T.2    Williamson, J.R.3    Reed, J.C.4
  • 3
    • 0027787791 scopus 로고
    • BCL-2 prevents killing of neuronal cells by glutamate but not by amyloid beta protein
    • Behl C, Hovey L, Krajewski S, Schubert D, Reed JC (1993) BCL-2 prevents killing of neuronal cells by glutamate but not by amyloid beta protein. Biochem Biophys Res Com 197: 949-956
    • (1993) Biochem Biophys Res Com , vol.197 , pp. 949-956
    • Behl, C.1    Hovey, L.2    Krajewski, S.3    Schubert, D.4    Reed, J.C.5
  • 5
    • 0029736955 scopus 로고    scopus 로고
    • Spatiotemporal Relationship of Apoptotic Cell Death to Lymphomonocytic Infiltration in Photochemically Induced Focal Ischemia of the Rat Cerebral Cortex
    • Braun JS, Jander S, Schroeter M, Witte OW, Stoll G (1996) Spatiotemporal Relationship Of Apoptotic Cell Death to Lymphomonocytic Infiltration In Photochemically Induced Focal Ischemia Of the Rat Cerebral Cortex. Acta Neuropathol 92: 255-263
    • (1996) Acta Neuropathol , vol.92 , pp. 255-263
    • Braun, J.S.1    Jander, S.2    Schroeter, M.3    Witte, O.W.4    Stoll, G.5
  • 6
    • 0029614765 scopus 로고
    • Neural apopiosis
    • Bredesen DE (1995) Neural apopiosis. Ann Neurol 38: 839-851
    • (1995) Ann Neurol , vol.38 , pp. 839-851
    • Bredesen, D.E.1
  • 7
  • 8
    • 0030179929 scopus 로고    scopus 로고
    • Pitfalls in the evaluation of apoptosis using TUNEL
    • Cervos-Navarro J, Schubert TEO (1996) Pitfalls in the evaluation of apoptosis using TUNEL. Brain Pathol 6: 347
    • (1996) Brain Pathol , vol.6 , pp. 347
    • Cervos-Navarro, J.1    Schubert, T.E.O.2
  • 9
    • 0026497926 scopus 로고
    • Excitotoxic cell death
    • Choi DW (1992) Excitotoxic cell death. J Neurobiol 23: 1261-1276
    • (1992) J Neurobiol , vol.23 , pp. 1261-1276
    • Choi, D.W.1
  • 10
    • 0029245289 scopus 로고
    • A potential role for apoptosis in neurodegeneration and Alzheimer's disease
    • Cotman CW, Anderson AJ (1995) A potential role for apoptosis in neurodegeneration and Alzheimer's disease. Mol Neurobiol 10: 19-45
    • (1995) Mol Neurobiol , vol.10 , pp. 19-45
    • Cotman, C.W.1    Anderson, A.J.2
  • 11
    • 0029912056 scopus 로고    scopus 로고
    • Mechanisms of Neuronal Death in Alzheimers Disease
    • Cotman CW, Su JH (1996) Mechanisms Of Neuronal Death In Alzheimers Disease. Brain Pathol 6: 493-506
    • (1996) Brain Pathol , vol.6 , pp. 493-506
    • Cotman, C.W.1    Su, J.H.2
  • 13
    • 0028343507 scopus 로고
    • Neonatal motoneurons overexpressing the bcl-2 protooncogene in transgenic mice are protected from axotomy-induced cell death
    • Dubois-Dauphin M, Frankowski H, Tsujimoto Y, Huarte J, Martinou JC (1994) Neonatal motoneurons overexpressing the bcl-2 protooncogene in transgenic mice are protected from axotomy-induced cell death. Proc Natl Acad Sci USA 91: 3309-3313
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3309-3313
    • Dubois-Dauphin, M.1    Frankowski, H.2    Tsujimoto, Y.3    Huarte, J.4    Martinou, J.C.5
  • 14
    • 0026648674 scopus 로고
    • Identification of Programmed Cell Death in Situ via Specific Labeling of Nuclear DnA Fragmentation
    • Gavrieli Y, Sherman Y, Ben-Sasson SA (1992) Identification of Programmed Cell Death In Situ via Specific Labeling of Nuclear DnA Fragmentation. J Cell Biol 119: 493-501
    • (1992) J Cell Biol , vol.119 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben-Sasson, S.A.3
  • 15
    • 0000064578 scopus 로고    scopus 로고
    • Altered expression of Bcl-2, Bcl-X, Bax, and c-Fos colocalizes with DNA fragmentation and ischemic cell damage following middle cerebral artery occlusion in rats
    • Gillardon F, Lenz C, Waschke KF, Krajewski S, Reed JC, Zimmermann M, Kuschinsky W (1996) Altered expression of Bcl-2, Bcl-X, Bax, and c-Fos colocalizes with DNA fragmentation and ischemic cell damage following middle cerebral artery occlusion in rats. Mol Brain Res 40: 254-260
    • (1996) Mol Brain Res , vol.40 , pp. 254-260
    • Gillardon, F.1    Lenz, C.2    Waschke, K.F.3    Krajewski, S.4    Reed, J.C.5    Zimmermann, M.6    Kuschinsky, W.7
  • 18
    • 0029879631 scopus 로고    scopus 로고
    • Immunohistochemical Detection of Bax and Bcl-2 Proteins in Gerbil Hippocampus Following Transient Forebrain Ischemia
    • Hara A, Iwai T, Niwa M, Uematsu T, Yoshimi N, Tanaka T, Mori H (1996) Immunohistochemical Detection Of Bax and Bcl-2 Proteins In Gerbil Hippocampus Following Transient Forebrain Ischemia. Brain Res 711: 249-253
    • (1996) Brain Res , vol.711 , pp. 249-253
    • Hara, A.1    Iwai, T.2    Niwa, M.3    Uematsu, T.4    Yoshimi, N.5    Tanaka, T.6    Mori, H.7
  • 21
    • 0027298139 scopus 로고
    • Disturbances of cerebral protein synthesis and ischemic cell death
    • Hossmann KA (1993) Disturbances of cerebral protein synthesis and ischemic cell death. Prog Brain Res 96: 161-177
    • (1993) Prog Brain Res , vol.96 , pp. 161-177
    • Hossmann, K.A.1
  • 22
    • 0031239774 scopus 로고    scopus 로고
    • C-Jun protein is expressed in degenerating retinal ganglion cells after optic nerve lesion in the rat
    • Isenmann S. Bähr M (1997b) c-Jun protein is expressed in degenerating retinal ganglion cells after optic nerve lesion in the rat. Exp Neurol 147: 28-36
    • (1997) Exp Neurol , vol.147 , pp. 28-36
    • Isenmann, S.1    Bähr, M.2
  • 23
    • 0029877026 scopus 로고    scopus 로고
    • Telencephalic Transplants in Mice - Characterization of Growth and Differentiation Patterns
    • Isenmann S, Brandner S, Sure U, Aguzzi A (1996) Telencephalic Transplants In Mice - Characterization Of Growth and Differentiation Patterns. Neuropathol Appl Neurobiol 22: 108-117
    • (1996) Neuropathol Appl Neurobiol , vol.22 , pp. 108-117
    • Isenmann, S.1    Brandner, S.2    Sure, U.3    Aguzzi, A.4
  • 24
    • 0030851891 scopus 로고    scopus 로고
    • Upregulation of Bax Protein in Degenerating Retinal Ganglion Cells precedes Apoptotic Cell Death after Optic Nerve Lesion in the Rat
    • Isenmann S, Wahl C, Krajewski S, Reed JC, Bähr M (1997a) Upregulation of Bax Protein in Degenerating Retinal Ganglion Cells precedes Apoptotic Cell Death after Optic Nerve Lesion in the Rat. Eur J Neurosci 9: 1763-1772
    • (1997) Eur J Neurosci , vol.9 , pp. 1763-1772
    • Isenmann, S.1    Wahl, C.2    Krajewski, S.3    Reed, J.C.4    Bähr, M.5
  • 25
    • 0028854369 scopus 로고
    • Lymphocytic infiltration and expression of intercellular adhesion molecule-1 in photochemically induced ischemia of the rat cortex
    • Jander S, Kraemer M, Schroeter M, Witte OW, Stoll G (1995) Lymphocytic infiltration and expression of intercellular adhesion molecule-1 in photochemically induced ischemia of the rat cortex. J Cereb Blood Flow Metab 15: 42-51
    • (1995) J Cereb Blood Flow Metab , vol.15 , pp. 42-51
    • Jander, S.1    Kraemer, M.2    Schroeter, M.3    Witte, O.W.4    Stoll, G.5
  • 28
    • 0030599159 scopus 로고    scopus 로고
    • Pharmacological Characterization of Apoptotic Cell Death in a Model of Photothrombotic Brain Injury in Rats
    • Kharlamov A, Uz T, Joo JY, Manev H (1996) Pharmacological Characterization Of Apoptotic Cell Death In a Model Of Photothrombotic Brain Injury In Rats. Brain Res 734: 1-9
    • (1996) Brain Res , vol.734 , pp. 1-9
    • Kharlamov, A.1    Uz, T.2    Joo, J.Y.3    Manev, H.4
  • 29
    • 0028060247 scopus 로고
    • Reversal of chemoresistance of lymphoma cells by antisense-mediated reduction of bcl-2 gene expression
    • Kitada S, Takayama S, De Riel K, Tanaka S, Reed JC (1994) Reversal of chemoresistance of lymphoma cells by antisense-mediated reduction of bcl-2 gene expression. Antisense Res Dev 4: 71-79
    • (1994) Antisense Res Dev , vol.4 , pp. 71-79
    • Kitada, S.1    Takayama, S.2    De Riel, K.3    Tanaka, S.4    Reed, J.C.5
  • 30
    • 0030861571 scopus 로고    scopus 로고
    • Bcl-2 and Bax function independently to regulate cell death
    • Knudson CM, Korsmeyer SJ (1997) Bcl-2 and Bax function independently to regulate cell death. Nat Genet 16: 358-363
    • (1997) Nat Genet , vol.16 , pp. 358-363
    • Knudson, C.M.1    Korsmeyer, S.J.2
  • 31
    • 0031059570 scopus 로고    scopus 로고
    • Immunohistochemical analysis of Bcl-2, Bcl-X, Mcl-1, and Bax in tumors of central and peripheral nervous system
    • Krajewski S, Krajewska M, Ehrmann J, Sikorska M, Lach B, Chatten J, Reed JC (1997) Immunohistochemical analysis of Bcl-2, Bcl-X, Mcl-1, and Bax in tumors of central and peripheral nervous system. Am J Pathol 150: 805-814
    • (1997) Am J Pathol , vol.150 , pp. 805-814
    • Krajewski, S.1    Krajewska, M.2    Ehrmann, J.3    Sikorska, M.4    Lach, B.5    Chatten, J.6    Reed, J.C.7
  • 32
    • 0028036895 scopus 로고
    • Immunohistochemical determination of in vivo distribution of Bax, a dominant inhibitor of Bcl-2
    • Krajewski S, Krajewska M, Shabaik A, Miyashita T, Wang HG, Reed JC (1994) Immunohistochemical determination of in vivo distribution of Bax, a dominant inhibitor of Bcl-2. Am J Pathol 145: 1323-1336
    • (1994) Am J Pathol , vol.145 , pp. 1323-1336
    • Krajewski, S.1    Krajewska, M.2    Shabaik, A.3    Miyashita, T.4    Wang, H.G.5    Reed, J.C.6
  • 35
    • 0027362667 scopus 로고
    • Investigations of the subcellular distribution of the bcl-2 oncoprotein: Residence in the nuclear envelope, endoplasmatic reticulum, and outer mitochondrial membranes
    • Krajewski S, Tanaka S, Takayama S, Schibler MJ, Fenton W, Reed JC (1993) Investigations of the subcellular distribution of the bcl-2 oncoprotein: residence in the nuclear envelope, endoplasmatic reticulum, and outer mitochondrial membranes. Cancer Res 53: 4701-4714
    • (1993) Cancer Res , vol.53 , pp. 4701-4714
    • Krajewski, S.1    Tanaka, S.2    Takayama, S.3    Schibler, M.J.4    Fenton, W.5    Reed, J.C.6
  • 36
    • 0026928928 scopus 로고
    • Oskar and Cecile Vogt, Lenin's brain and the bumble-bees of the Black Forest
    • Kreutzberg GW, Klatzo I, Kleihues P (1992) Oskar and Cecile Vogt, Lenin's brain and the bumble-bees of the Black Forest. Brain Pathol 2: 363-371
    • (1992) Brain Pathol , vol.2 , pp. 363-371
    • Kreutzberg, G.W.1    Klatzo, I.2    Kleihues, P.3
  • 37
    • 0028216444 scopus 로고
    • Evidence that BCL-2 represses apoptosis by regulating endoplasmic reticulum-associated Ca2+ fluxes
    • Lam M, Dubyak G, Chen L, Nunez G, Miesfeld RL, Distelhorst CW (1994) Evidence that BCL-2 represses apoptosis by regulating endoplasmic reticulum-associated Ca2+ fluxes. Proc Natl Acad Sci USA 91: 6569-6573
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 6569-6573
    • Lam, M.1    Dubyak, G.2    Chen, L.3    Nunez, G.4    Miesfeld, R.L.5    Distelhorst, C.W.6
  • 38
    • 0025732732 scopus 로고
    • Dose-dependent induction of apoptosis in human tumour cell lines by widely diverging stimuli
    • Lennon SV, Martin SJ, Cotter TG (1991) Dose-dependent induction of apoptosis in human tumour cell lines by widely diverging stimuli. Cell Prolif 24: 203-214
    • (1991) Cell Prolif , vol.24 , pp. 203-214
    • Lennon, S.V.1    Martin, S.J.2    Cotter, T.G.3
  • 39
    • 0028905230 scopus 로고
    • Temporal profile of in situ DNA fragmentation after transient middle cerebral artery occlusion in the rat
    • Li Y, Chopp M, Jiang N, Yao F, Zaloga C (1995) Temporal profile of in situ DNA fragmentation after transient middle cerebral artery occlusion in the rat. J Cereb Blood Flow Metab 15: 389-397
    • (1995) J Cereb Blood Flow Metab , vol.15 , pp. 389-397
    • Li, Y.1    Chopp, M.2    Jiang, N.3    Yao, F.4    Zaloga, C.5
  • 40
    • 0028981908 scopus 로고
    • Expression of bct-2 from a defective herpes simplex virus-1 vector limits neuronal death in focal cerebral ischemia
    • Linnik MD, Zahos P, Geschwind MD, Federoff HJ (1995) Expression of bct-2 from a defective herpes simplex virus-1 vector limits neuronal death in focal cerebral ischemia. Stroke 26: 1670-1674
    • (1995) Stroke , vol.26 , pp. 1670-1674
    • Linnik, M.D.1    Zahos, P.2    Geschwind, M.D.3    Federoff, H.J.4
  • 41
    • 0027501851 scopus 로고
    • Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats
    • Linnik MD, Zobrist RH, Hatfield MD (1993) Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats. Stroke 24: 2002-2008
    • (1993) Stroke , vol.24 , pp. 2002-2008
    • Linnik, M.D.1    Zobrist, R.H.2    Hatfield, M.D.3
  • 42
    • 0028567078 scopus 로고
    • Photochemical brain injury in rats triggers DNA fragmentation, p53 and HSP72
    • Manev H, Kharlamov A, Armstrong DM (1994) Photochemical brain injury in rats triggers DNA fragmentation, p53 and HSP72. Neuroreport 5: 2661-2664
    • (1994) Neuroreport , vol.5 , pp. 2661-2664
    • Manev, H.1    Kharlamov, A.2    Armstrong, D.M.3
  • 45
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltvai ZN, Milliman CL, Korsmeyer SJ (1993) Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74: 609-619
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 47
    • 0028040019 scopus 로고
    • Bcl-2 and the regulation of programmed cell death
    • Reed JC (1994) Bcl-2 and the regulation of programmed cell death. J Cell Biol 124: 1-6
    • (1994) J Cell Biol , vol.124 , pp. 1-6
    • Reed, J.C.1
  • 48
    • 0028282502 scopus 로고
    • Immunolocalization of calpain I-mediated spectrin degradation to vulnerable neurons in the ischemic gerbil brain
    • Roberts-Lewis JM, Savage MJ, Marcy VR, Pinsker LR, Siman R (1994) Immunolocalization of calpain I-mediated spectrin degradation to vulnerable neurons in the ischemic gerbil brain. J Neurosci 14: 3934-3944
    • (1994) J Neurosci , vol.14 , pp. 3934-3944
    • Roberts-Lewis, J.M.1    Savage, M.J.2    Marcy, V.R.3    Pinsker, L.R.4    Siman, R.5
  • 51
    • 0029127992 scopus 로고
    • Selective neuronal vulnerability in the hippocampus - A role for gene expression?
    • Schreiber SS, Baudry M (1995) Selective neuronal vulnerability in the hippocampus - a role for gene expression? Trends Neurosci 18: 446-451
    • (1995) Trends Neurosci , vol.18 , pp. 446-451
    • Schreiber, S.S.1    Baudry, M.2
  • 54
    • 0027963452 scopus 로고
    • Increase in bcl-2 oncoprotein and the tolerance to ischemia-induced neuronal death in the gerbil hippocampus
    • Shimazaki K, Ishida A, Kawai N (1994) Increase in bcl-2 oncoprotein and the tolerance to ischemia-induced neuronal death in the gerbil hippocampus. Neurosci Res 20: 95-99
    • (1994) Neurosci Res , vol.20 , pp. 95-99
    • Shimazaki, K.1    Ishida, A.2    Kawai, N.3
  • 56
    • 0026782517 scopus 로고
    • Pathophysiology and treatment of focal cerebral ischemia. Part II: Mechanisms of damage and treatment
    • Siesjö BK (1992) Pathophysiology and treatment of focal cerebral ischemia. Part II: Mechanisms of damage and treatment. J Neurosurg 77: 337-354
    • (1992) J Neurosurg , vol.77 , pp. 337-354
    • Siesjö, B.K.1
  • 57
    • 0029952943 scopus 로고    scopus 로고
    • DNA fragmentation and HSP70 protein induction in hippocampus and cortex occurs in separate neurons following permanent middle cerebral artery occlusions
    • States BA, Honkaniemi J, Weinstein PR, Sharp FR (1996) DNA fragmentation and HSP70 protein induction in hippocampus and cortex occurs in separate neurons following permanent middle cerebral artery occlusions. J Cereb Blood Flow Metab 16: 1165-1175
    • (1996) J Cereb Blood Flow Metab , vol.16 , pp. 1165-1175
    • States, B.A.1    Honkaniemi, J.2    Weinstein, P.R.3    Sharp, F.R.4
  • 58
    • 0028873247 scopus 로고
    • P53-independent apoptotic and necrotic cell deaths induced by adenovirus infection: Suppression by E1B 19K and Bct-2 proteins
    • Subramanian T, Tarodi B, Chinnadurai G (1995) p53-independent apoptotic and necrotic cell deaths induced by adenovirus infection: suppression by E1B 19K and Bct-2 proteins. Cell Growth Diff 6: 131-137
    • (1995) Cell Growth Diff , vol.6 , pp. 131-137
    • Subramanian, T.1    Tarodi, B.2    Chinnadurai, G.3
  • 59
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • Thompson CB (1995) Apoptosis in the pathogenesis and treatment of disease. Science 257: 1456-1462
    • (1995) Science , vol.257 , pp. 1456-1462
    • Thompson, C.B.1
  • 60
    • 0021826450 scopus 로고
    • Induction of reproducible brain infarction by photochemically initiated thrombosis
    • Watson BD, Dietrich WD, Busto R, Wachtel MS, Ginsberg MD (1985) Induction of reproducible brain infarction by photochemically initiated thrombosis. Ann Neurol 17: 497-504
    • (1985) Ann Neurol , vol.17 , pp. 497-504
    • Watson, B.D.1    Dietrich, W.D.2    Busto, R.3    Wachtel, M.S.4    Ginsberg, M.D.5
  • 61
    • 0031561725 scopus 로고    scopus 로고
    • The temporal relationship between protein phosphatase, ICE/CED-3 proteases, intraceltular acidification, and DNA fragmentation in apoptosis
    • Wolf CM, Reynolds JE, Morana SJ, Eastman A (1997) The temporal relationship between protein phosphatase, ICE/CED-3 proteases, intraceltular acidification, and DNA fragmentation in apoptosis. Exp Cell Res 230: 22-27
    • (1997) Exp Cell Res , vol.230 , pp. 22-27
    • Wolf, C.M.1    Reynolds, J.E.2    Morana, S.J.3    Eastman, A.4
  • 62
    • 0028206341 scopus 로고
    • BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerizatton with Bax
    • Yin XM, Oltval ZN, Korsmeyer SJ (1994) BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerizatton with Bax. Nature 369: 321-323
    • (1994) Nature , vol.369 , pp. 321-323
    • Yin, X.M.1    Oltval, Z.N.2    Korsmeyer, S.J.3
  • 63
    • 0027304383 scopus 로고
    • BCL-2 blocks glutamate toxicity in neural cell lines
    • Zhong LT, Kane DJ, Bredesen DE (1993) BCL-2 blocks glutamate toxicity in neural cell lines. Mol Brain Res 19: 353-355
    • (1993) Mol Brain Res , vol.19 , pp. 353-355
    • Zhong, L.T.1    Kane, D.J.2    Bredesen, D.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.