Piperine suppresses cerebral ischemia-reperfusion-induced inflammation through the repression of COX-2, NOS-2, and NF-κB in middle cerebral artery occlusion rat model

Molecular and Cellular Biochemistry

Volumn 367, Issue 1-2, 2012, Pages 73-84

  Vaibhav, Kumar ^a   Shrivastava, Pallavi ^a,b   Javed, Hayate ^a   Khan, Andleeb ^a   Ahmed, Md Ejaz ^a   Tabassum, Rizwana ^a   Khan, Mohd Moshahid ^a,d   Khuwaja, Gulrana ^a,c   Islam, Farah ^c,e   Saeed Siddiqui, M ^a   Safhi, Mohammed M ^c   Islam, Fakhrul ^a,c  

^a HAMDARD UNIVERSITY   (India)

^b UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY   (United States)

^c JAZAN UNIVERSITY   (Saudi Arabia)

^d UNIVERSITY OF IOWA   (United States)

^e HAMDARD UNIVERSITY   (India)

Author keywords

Behavioral deficit; COX 2; MCAO; NF B; NOS 2; Piperine

Indexed keywords

CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; NITRIC OXIDE SYNTHASE; PIPERINE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; HISTOPATHOLOGY; INFLAMMATION; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MORPHOLOGY; NONHUMAN; PATHOPHYSIOLOGY; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; STATISTICAL SIGNIFICANCE;

ALKALOIDS; ANIMALS; ANTI-INFLAMMATORY AGENTS; BENZODIOXOLES; CYCLOOXYGENASE 2; CYTOKINES; DOWN-REGULATION; INFARCTION, MIDDLE CEREBRAL ARTERY; INFLAMMATION MEDIATORS; MALE; MOTOR ACTIVITY; MUSCLE STRENGTH; NEUROPROTECTIVE AGENTS; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; PIPERIDINES; POLYUNSATURATED ALKAMIDES; RATS; RATS, WISTAR; REPERFUSION INJURY;

RATTUS; RATTUS NORVEGICUS;

EID: 84863481787     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-012-1321-z     Document Type: Article

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