Gypenosides improve cognitive impairment induced by chronic cerebral hypoperfusion in rats by suppressing oxidative stress and astrocytic activation

Behavioural Pharmacology

Volumn 22, Issue 7, 2011, Pages 633-644

  Zhang, Guang Lin ^a,c   Deng, Jian Ping ^a   Wang, Ben Han ^c   Zhao, Zhen Wei ^a   Li, Jiang ^a   Gao, Li ^a   Liu, Bo Lin ^b   Xong, Jia Rui ^c   Guo, Xiao Dong ^c   Yan, Zhi Qiang ^a   Gao, Guo Dong ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c Department of Neurosurgery   (China)

Author keywords

Astrocytes; chronic cerebral hypoperfusion; gypenosides; oxidative stress; rat spatial learning and memory

Indexed keywords

4 HYDROXYNONENAL; 8 HYDROXYDEOXYGUANOSINE; ANTIOXIDANT; GYPENOSIDE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN CORTEX; BRAIN PERFUSION; CELL ACTIVATION; CHRONIC BRAIN DISEASE; COGNITIVE DEFECT; CONTROLLED STUDY; DNA DAMAGE; DRUG EFFECT; HIPPOCAMPAL CA1 REGION; IMMUNOHISTOCHEMISTRY; LEARNING; LIPID PEROXIDATION; MALE; MAZE TEST; NONHUMAN; OXIDATIVE STRESS; RAT; SPATIAL MEMORY; SPRAGUE DAWLEY RAT; WESTERN BLOTTING;

ANIMALS; ASTROCYTES; BIOLOGICAL ASSAY; BRAIN ISCHEMIA; CA1 REGION, HIPPOCAMPAL; CHRONIC DISEASE; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; DRUG EVALUATION, PRECLINICAL; DRUGS, CHINESE HERBAL; GYNOSTEMMA; MALE; MAZE LEARNING; MEMORY, SHORT-TERM; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PARIETAL LOBE; PHYTOTHERAPY; PLANT EXTRACTS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; SWIMMING;

EID: 80052955902     PISSN: 09558810     EISSN: 14735849     Source Type: Journal    
DOI: 10.1097/FBP.0b013e32834afef9     Document Type: Article

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