Cellular and molecular mechanisms activating the cell death processes by chalcones: Critical structural effects

Toxicology in Vitro

Volumn 27, Issue 8, 2013, Pages 2305-2315

  Champelovier, Pierre ^a   Chauchet, Xavier ^b   Hazane Puch, Florence ^a   Vergnaud, Sabrina ^a   Garrel, Catherine ^a   Laporte, François ^a   Boutonnat, Jean ^a   Boumendjel, Ahcène ^c  

^a HÔPITAL MICHALLON   (France)

^b LABORATOIRE TIMC IMAG   (France)

^c UNIV GRENOBLE ALPES   (France)

Author keywords

Apoptosis; Autophagy; Caspases; Chalcones; ROS

Indexed keywords

1,3 DIPHENYLPROPENONE; CASPASE 3; CASPASE 8; CASPASE 9; CD71 ANTIGEN; CHALCONE A; CHALCONE B; CHALCONE DERIVATIVE; CHEMICAL COMPOUND; CYCLIN B; CYCLIN DEPENDENT KINASE 1; DIMETHYL SULFOXIDE; JAI 58; KI 67 ANTIGEN; MBL II 58; PROTEIN BAX; PROTEIN BCL 2; UNCLASSIFIED DRUG;

ANTIGEN EXPRESSION; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL CULTURE; CELL DEATH; CHEMICAL STRUCTURE; CONTROLLED STUDY; ENZYME ACTIVATION; GLIOBLASTOMA; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; PROTEIN SYNTHESIS;

(1)H NMR; 1,1,3,3-TETRAETHOXYPROPANE; 2′,7′-DICHLOROFLUORESCEIN DIACETATE; 3,3′ DIHEXYLOXACARBOCYANINE IODIDE; APOPTOSIS; ATG; AUTOPHAGY; AUTOPHAGY RELATED GENES; BAK; BAX; BCL-2 HOMOLOGOUS ANTAGONIST KILLER; BCL-2 INTERACTING MEDIATOR OF CELL DEATH; BCL-2-ASSOCIATED X PROTEIN; BCRP; BIM; BOVINE SERUM ALBUMINE; BREAST CANCER RESISTANCE PROTEIN; BSA; CASPASES; CAT; CATALASE; CCD; CDC25; CDK; CELL DIVISION CYCLE 25; CHALCONES; CHARGE-COUPLED DEVICE; CHECKPOINT KINASE 2; CHK2; CYCLIN DEPENDENT KINASE; DCFDA; DHR; DIHYDRORHODAMINE-123; DIMETHYLSULFOXIDE; DIOC6; DMSO; EDTA; ERK1/2; ETHYLENEDIAMINETETRAACETIC ACID; EXTRACELLULAR SIGNAL-REGULATED KINASE 1/2; GLUTATHIONE PEROXIDASE 1; GPX1; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HPLC; HRPT1; HYDROGEN-1 NUCLEAR MAGNETIC RESONANCE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE 1; MALONDIALDEHYDE; MAMMALIAN TARGET OF RAPAMYCIN (MTOR); MAY GRUNWALD GIEMSA; MDA; MDC; MEAN FLUORESCENCE INTENSITY; MFI; MGG; MI; MITOCHONDRIAL TRANSMEMBRANE POTENTIAL; MITOTIC INDEX; MONODANSYLCADAVERINE; MTOR; MTP OR ΔΨM; N-ACETYLCYSTEIN; NAC; NADPH; NHNBC; NHSF; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; NORMAL HUMAN NUCLEATED BLOOD CELLS; NORMAL HUMAN SKIN FIBROBLASTS; P-GLYCOPROTEIN; P-GP; PBS; PCD; PHOSPHATE BUFFERED SALINE; PROGRAMMED CELL DEATH; REACTIVE OXYGEN SPECIES; ROS; TBA; TEP; THIOBARBITURIC ACID;

ANTINEOPLASTIC AGENTS; CATALASE; CELL CYCLE; CELL DEATH; CELL LINE, TUMOR; CHALCONES; GLUTATHIONE PEROXIDASE; HUMANS; MALONDIALDEHYDE; MITOTIC INDEX; REACTIVE OXYGEN SPECIES;

EID: 84887014167     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2013.09.021     Document Type: Article

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