2′,5′-Dihydroxychalcone-induced glutathione is mediated by oxidative stress and kinase signaling pathways

Free Radical Biology and Medicine

Volumn 51, Issue 6, 2011, Pages 1146-1154

  Kachadourian, Remy ^a,b   Pugazhenthi, Subbiah ^b,c   Velmurugan, Kalpana ^c   Backos, Donald S ^b   Franklin, Christopher C ^b   McCord, Joe M ^b   Day, Brian J ^a,b  

^a DEPARTMENT OF MEDICINE   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

AP 1; Free radicals; MCF 7 AREc32; Metalloporphyrin; Nrf2; ROS

Indexed keywords

2',5' DIHYDROXYCHALCONE; CHALCONE DERIVATIVE; GLUTATHIONE; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 14; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; ANTIOXIDANT; CHALCONE; DRUG DERIVATIVE; MANGANESE (III) MESO TETRAKIS(N ETHYLPYRIDINIUM 2 YL)PORPHYRIN; MANGANESE (III) MESO-TETRAKIS(N-ETHYLPYRIDINIUM-2-YL)PORPHYRIN; METALLOPORPHYRIN; STRESS ACTIVATED PROTEIN KINASE;

ANTIOXIDANT ACTIVITY; ARTICLE; CANCER CELL CULTURE; CATALYSIS; CELL LEVEL; CONTROLLED STUDY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REPORTER GENE; SIGNAL TRANSDUCTION; CHEMISTRY; DNA RESPONSIVE ELEMENT; DRUG EFFECT; GENETICS; METABOLISM; TRANSCRIPTION INITIATION; TUMOR CELL LINE;

ANTIOXIDANTS; CELL LINE, TUMOR; CHALCONE; GLUTATHIONE; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; METALLOPORPHYRINS; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RESPONSE ELEMENTS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTIONAL ACTIVATION;

EID: 80051795536     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.05.041     Document Type: Article

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