Alpha-eleostearic acid induces autophagy-dependent cell death through targeting AKT/mTOR and ERK1/2 signal together with the generation of reactive oxygen species

Biochemical and Biophysical Research Communications

Volumn 391, Issue 1, 2010, Pages 903-908

  Eom, Jung Min ^a   Seo, Min Ji ^a   Baek, Ji Young ^a   Chu, Hyuk ^b   Han, Seung Hyun ^c   Min, Tae Sun ^d   Cho, Chong su ^a   Yun, Cheol Heui ^a  

^a Seoul National University   (South Korea)

^b Korea National Institute of Health   (South Korea)

^c School of Dentistry   (South Korea)

^d National Research Foundation of Korea   (South Korea)

Author keywords

Alpha eleostearic acid; Apoptosis; Autophagy; Reactive oxygen species

Indexed keywords

ACETYLCYSTEINE; ALPHA ELEOSTEARIC ACID; ANTINEOPLASTIC AGENT; DANSYLCADAVERINE; LINOLENIC ACID; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; S6 KINASE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; AUTOPHAGY; CELL CYCLE G1 PHASE; CELL DEATH; COMPETITIVE INHIBITION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HELA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN TARGETING; SIGNAL TRANSDUCTION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; AUTOPHAGY; HELA CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LINOLENIC ACIDS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES;

EID: 72949115495     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.11.161     Document Type: Article

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