Structural requirement of arylindolylpropenones as anti-bladder carcinoma cells agents

Bioorganic and Medicinal Chemistry

Volumn 19, Issue 20, 2011, Pages 6143-6148

  Martel Frachet, Véronique ^a   Kadri, Malika ^a   Boumendjel, Ahcne ^a   Ronot, Xavier ^a  

^a UNIV GRENOBLE ALPES   (France)

Author keywords

Antitumor agents; Arylindolylpropenones; Bladder cancer; Cell cycle

Indexed keywords

1 (1 METHYL 1H INDOL 3 YL) 3 (2,4,6 TRIMETHOXYPHENYL)PROPENONE; 1 (1 METHYL 1H INDOL 3 YL) 3 (3,4,5 TRIMETHOXYPHENYL)PROPENONE; 1 (1 METHYL 1H INDOL 3 YL) 3 [2 (4 METHYLPIPERAZIN 1 YL)PHENYL]PROPENONE; 1 (1 METHYL 1H INDOL 3 YL) 3 [4 (4 METHYLPIPERAZIN 1 YL)PHENYL]PROPENONE; 1 (1 METHYL 1H INDOL 3 YL) 3 PHENYLPROPENONE; 1 (5 METHYL 1 METHYL 1H INDOL 3 YL) 3 (2,4,6 TRIMETHOXYPHENYL)PROPENONE; 1 (N METHYLINDOLYL) 3 PHENYLPROPENONE; 1 METHYL 3 [3 (2,4,6 TRIMETHOXYPHENYL)ACRYLOYL] 1H INDOLE 5 CARBOXYLIC ACID; 1,3 BIS(1 METHYL 1H INDOL 3 YL)PROPENONE; 3 (1 METHYL 1H INDOL 5 YL) 1 (1 METHYL 1H INDOL 3 YL)PROPENONE; 3 (1 METHYL 1H INDOL 5 YL) 1 (2,4,6 TRIMETHOXYPHENYL)PROPENONE; 3 (2 FLUOROPHENYL) 1 (1 METHYL 1H INDOL 3 YL)PROPENONE; 3 (2,4 DIMETHOXYPHENYL) 1 (1 METHYL 1H INDOL 3 YL)PROPENONE; 3 (2,6 DICHLOROPHENYL) 1 (1 METHYL 1H INDOL 3 YL)PROPENONE; 3 (2,6 DIMETHOXYPHENYL) 1 (1 METHYL 1H INDOL 3 YL)PROPENONE; 3 (4 DIMETHYLAMINO PHENYL) 1 (1 METHYL 1H INDOL 3 YL)PROPENONE; ANTINEOPLASTIC AGENT; CHALCONE DERIVATIVE; CISPLATIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BLADDER CARCINOMA; CARCINOMA CELL; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CHALCONES; HUMANS; STRUCTURE-ACTIVITY RELATIONSHIP; URINARY BLADDER NEOPLASMS;

EID: 80053261204     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2011.08.015     Document Type: Article

References (29)

1. J. Ferlay, H.R. Shin, F. Bray, D. Forman, C. Mathers, and D.M. Parkin Int. J. Cancer 127 2010 2893
2. B.L. Jacobs, C.T. Lee, and J.E. Montie C.A. Cancer J. Clin. 60 2010 244
3. D.J. Gallagher, M.I. Milowsky, and D.F. Bajorin Cancer 113 2008 1284
4. M.A. Ghoneim, and H. Abol-Enein Nat. Clin. Pract. Urol. 5 2008 501
5. R.V. Laffaioli, A. Milano, and F. Caponigro Ann. Oncol. 18 2007 vi153
6. J.A. Garcia, and R. Dreicer J. Clin. Oncol. 24 2006 5545
7. C.N. Sternberg, S.M. Donat, J. Bellmunt, R.E. Millikan, W. Stadler, P. De Mulder, A. Sherif, H. von der Maase, T. Tsukamoto, and M.S. Soloway Urology 69 2007 62
8. D.I. Batovska, and I.T. Todorova Curr. Clin. Pharmacol. 5 2010 1
9. S. Ducki Anticancer Agents Med. Chem. 9 2009 336
10. C. Dyrager, M. Wickstrom, M. Friden-Saxin, A. Friberg, K. Dahlen, E.A. Wallen, J. Gullbo, M. Grotli, and K. Luthman Bioorg. Med. Chem. 19 2011 2659
11. R. Stoll, C. Renner, S. Hansen, S. Palme, C. Klein, A. Belling, W. Zeslawski, M. Kamionka, T. Rehm, P. Muhlhahn, R. Schumacher, F. Hesse, B. Kaluza, W. Voelter, R.A. Engh, and T.A. Holak Biochemistry 40 2001 336
12. A. Boumendjel, X. Ronot, and J. Boutonnat Curr. Drug Targets 10 2009 363
13. A. Kamal, G. Ramakrishna, P. Raju, A. Viswanath, M.J. Ramaiah, G. Balakishan, and M. Pal-Bhadra Bioorg. Med. Chem. Lett. 20 2010 4865
14. Y.K. Rao, T.Y. Kao, J.L. Ko, and Y.M. Tzeng Bioorg. Med. Chem. Lett. 20 2010 6508
15. A. Boumendjel, A. McLeer-Florin, P. Champelovier, D. Allegro, D. Muhammad, F. Souard, M. Derouazi, V. Peyrot, B. Toussaint, and J. Boutonnat BMC Cancer 9 2009 242
16. V. Martel-Frachet, J. Areguian, M. Blanc, B. Touquet, A. Lamarca, X. Ronot, and A. Boumendjel Anticancer Drugs 20 2009 469
17. C.J. Marshall, L.M. Franks, and A.W. Carbonell J. Natl. Cancer Inst. 58 1977 1743
18. J.R. Masters, P.J. Hepburn, L. Walker, W.J. Highman, L.K. Trejdosiewicz, S. Povey, M. Parkar, B.T. Hill, P.R. Riddle, and L.M. Franks Cancer Res. 46 1986 3630
19. D.C. Marks, L. Belov, M.W. Davey, R.A. Davey, and A.D. Kidman Leuk. Res. 16 1992 1165
20. D.J. Gallagher, and M.I. Milowsky Curr. Treat. Options Oncol. 10 2009 205
21. A. Boumendjel, J. Boccard, P.A. Carrupt, E. Nicolle, M. Blanc, A. Geze, L. Choisnard, D. Wouessidjewe, E.L. Matera, and C. Dumontet J. Med. Chem. 51 2008 2307
22. V. Peyrot, D. Leynadier, M. Sarrazin, C. Briand, M. Menendez, J. Laynez, and J.M. Andreu Biochemistry 31 1992 11125
23. S. Ducki, R. Forrest, J.A. Hadfield, A. Kendall, N.J. Lawrence, A.T. McGown, and D. Rennison Bioorg. Med. Chem. Lett. 8 1998 1051
24. W.G. Ko, T.H. Kang, S.J. Lee, N.Y. Kim, Y.C. Kim, D.H. Sohn, and B.H. Lee Food Chem. Toxicol. 38 2000 861
25. N.J. Lawrence, and A.T. McGown Curr. Pharm. Des. 11 2005 1679
26. X. Liu, and M.L. Go Bioorg. Med. Chem. 14 2006 153
27. J. Rodriguez, J. Yanez, V. Vicente, M. Alcaraz, O. Benavente-Garcia, J. Castillo, J. Lorente, and J.A. Lozano Melanoma Res. 12 2002 99
28. M.L. Go, X. Wu, and X.L. Liu Curr. Med. Chem. 12 2005 481
29. Y. Kim do, K.H. Kim, N.D. Kim, K.Y. Lee, C.K. Han, J.H. Yoon, S.K. Moon, S.S. Lee, and B.L. Seong J. Med. Chem. 49 2006 5664