메뉴 건너뛰기




Volumn 87, Issue 5, 2013, Pages 783-798

Non-melanoma skin cancer in mouse and man

Author keywords

Chemical carcinogenesis; Ha ras signaling; Papilloma; Phorbol ester; Squamous cell carcinoma; Wnt signaling

Indexed keywords

7,12 DIMETHYLBENZ[A]ANTHRACENE; PHORBOL ESTER; TUMOR PROMOTER; PHORBOL 13 ACETATE 12 MYRISTATE;

EID: 84886928127     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-012-0998-9     Document Type: Review
Times cited : (49)

References (131)
  • 1
    • 0030464473 scopus 로고    scopus 로고
    • Quantitative analysis of cadherin-catenin-Actin reorganization during development of cell-cell adhesion
    • Adams CL, Nelson WJ, Smith SJ (1996) Quantitative analysis of cadherin-catenin-Actin reorganization during development of cell-cell adhesion. J Cell Biol 135(6 Pt 2):1899-1911
    • (1996) J7 Cell Biol , vol.135 , Issue.6 PART 2 , pp. 1899-1911
    • Adams, C.L.1    Nelson, W.J.2    Smith, S.J.3
  • 2
    • 0016203370 scopus 로고
    • Fine-structural identification and organization of the epidermal proliferative unit
    • Allen TD, Potten CS (1974) Fine-structural identification and organization of the epidermal proliferative unit. J Cell Sci 15(2):291-319
    • (1974) J Cell Sci , vol.15 , Issue.2 , pp. 291-319
    • Allen, T.D.1    Potten, C.S.2
  • 3
    • 0024236909 scopus 로고
    • Oncogene activation in chemical carcinogenesis
    • Balmain A, Brown K (1988) Oncogene activation in chemical carcinogenesis. Adv Cancer Res 51:147-182
    • (1988) Adv Cancer Res , vol.51 , pp. 147-182
    • Balmain, A.1    Brown, K.2
  • 5
    • 84966175904 scopus 로고
    • A new, quantitative, approach to the study of the stages of chemical cartinogenesis in the mouse's skin
    • Berenblum I, Shubik P (1947) A new, quantitative, approach to the study of the stages of chemical cartinogenesis in the mouse's skin. Br J Cancer 1(4):383-391
    • (1947) Br J Cancer , vol.1 , Issue.4 , pp. 383-391
    • Berenblum, I.1    Shubik, P.2
  • 6
    • 0016359084 scopus 로고
    • Lack of an effect of tumor-promoting phorbol esters and of epidermal g1 chalone or dna synthesis in the epidermis of newborn mice
    • Bertsch S, Marks F (1974) Lack of an effect of tumor-promoting phorbol esters and of epidermal G1 chalone or DNA synthesis in the epidermis of newborn mice. Cancer Res 34(12):3283-3288
    • (1974) Cancer Res , vol.34 , Issue.12 , pp. 3283-3288
    • Bertsch, S.1    Marks, F.2
  • 7
    • 75949142944 scopus 로고
    • Some biological aspects of skin carcinogenesis
    • Boutwell RK (1964) Some biological aspects of skin carcinogenesis. Prog Exp Tumor Res 19:207-250
    • (1964) Prog Exp Tumor Res , vol.19 , pp. 207-250
    • Boutwell, R.K.1
  • 8
    • 0020019772 scopus 로고
    • Mouse skin: A useful model system for studying the mechanism of chemical carcinogenesis
    • In: Hecker E, Fusenig N, Kunz W, Marks F, Thielmann HW, Raven Press, New York
    • Boutwell RK, Verma AK, Ashendel CL, Astrup E (1992) Mouse skin: a useful model system for studying the mechanism of chemical carcinogenesis. In: Hecker E, Fusenig N, Kunz W, Marks F, Thielmann HW (eds) Carcinogenesis: a comprehensive survey, vol 7. Raven Press, New York
    • (1992) Carcinogenesis: A Comprehensive Survey , vol.7
    • Boutwell, R.K.1    Verma, A.K.2    Ashendel, C.L.3    Astrup, E.4
  • 10
    • 0022458856 scopus 로고
    • V-ras genes from harvey and balb murine sarcoma viruses can act as initiators of two-stage mouse skin carcinogenesis
    • Brown K, Quintanilla M, Ramsden M, Kerr IB, Young S, Balmain A (1986) v-ras genes from Harvey and BALB murine sarcoma viruses can act as initiators of two-stage mouse skin carcinogenesis. Cell 46(3):447-456
    • (1986) Cell , vol.46 , Issue.3 , pp. 447-456
    • Brown, K.1    Quintanilla, M.2    Ramsden, M.3    Kerr, I.B.4    Young, S.5    Balmain, A.6
  • 11
    • 0025038030 scopus 로고
    • Carcinogen-induced mutations in the mouse c-ha-ras gene provide evidence of multiple pathways for tumor progression
    • Brown K, Buchmann A, Balmain A (1990) Carcinogen-induced mutations in the mouse c-Ha-ras gene provide evidence of multiple pathways for tumor progression. Proc Natl Acad Sci U S A 87(2):538-542
    • (1990) Proc Natl Acad Sci U S A , vol.87 , Issue.2 , pp. 538-542
    • Brown, K.1    Buchmann, A.2    Balmain, A.3
  • 12
    • 0032559976 scopus 로고    scopus 로고
    • The malignant capacity of skin tumours induced by expression of a mutant h-ras transgene depends on the cell type targeted
    • Brown K, Strathdee D, Bryson S, Lambie W, Balmain A (1998) The malignant capacity of skin tumours induced by expression of a mutant H-ras transgene depends on the cell type targeted. Curr Biol 8(9):516-524
    • (1998) Curr Biol , vol.8 , Issue.9 , pp. 516-524
    • Brown, K.1    Strathdee, D.2    Bryson, S.3    Lambie, W.4    Balmain, A.5
  • 13
    • 0026385870 scopus 로고
    • Progression of squamous carcinoma cells to spindle carcinomas of mouse skin is associated with an imbalance of h-ras alleles on chromosome 7
    • Buchmann A, Ruggeri B, Klein-Szanto AJ, Balmain A (1991) Progression of squamous carcinoma cells to spindle carcinomas of mouse skin is associated with an imbalance of H-ras alleles on chromosome 7. Cancer Res 51(15):4097-4101
    • (1991) Cancer Res , vol.51 , Issue.15 , pp. 4097-4101
    • Buchmann, A.1    Ruggeri, B.2    Klein-Szanto, A.J.3    Balmain, A.4
  • 14
    • 0020643404 scopus 로고
    • Approach to risk assessment for genotoxic carcinogens based on data from the mouse skin initiation-promotion model
    • Burns F, Albert R, Altshuler B, Morris E (1983) Approach to risk assessment for genotoxic carcinogens based on data from the mouse skin initiation-promotion model. Environ Health Perspect 50:309-320
    • (1983) Environ Health Perspect , vol.50 , pp. 309-320
    • Burns, F.1    Albert, R.2    Altshuler, B.3    Morris, E.4
  • 15
    • 54249125456 scopus 로고
    • Cancer progression in mouse skin
    • In: Saga TJ (ed), CRC Press, Boca Raton
    • Burns FJ, Albert RE, Altschuler B (1984) Cancer progression in mouse skin. In: Saga TJ (ed) Mechanisms of tumor promotion, vol 2. CRC Press, Boca Raton, pp 17-39
    • (1984) Mechanisms of Tumor Promotion , vol.2 , pp. 17-39
    • Burns, F.J.1    Albert, R.E.2    Altschuler, B.3
  • 16
    • 0030445276 scopus 로고    scopus 로고
    • Pkc epsilon functions as an oncogene by enhancing activation of the raf kinase
    • Cacace AM, Ueffing M, Philipp A, Han EKH, Kolch W, Weinstein IB (1996) PKC epsilon functions as an oncogene by enhancing activation of the Raf kinase. Oncogene 13(12):2517-2526
    • (1996) Oncogene , vol.13 , Issue.12 , pp. 2517-2526
    • Cacace, A.M.1    Ueffing, M.2    Philipp, A.3    Han, E.K.H.4    Kolch, W.5    Weinstein, I.B.6
  • 18
    • 0032953231 scopus 로고    scopus 로고
    • A common human skin tumour is caused by activating mutations in beta-catenin
    • Chan EF, Gat U, McNiff JM, Fuchs E (1999) A common human skin tumour is caused by activating mutations in beta-catenin. Nat Genet 21(4):410-413
    • (1999) Nat Genet , vol.21 , Issue.4 , pp. 410-413
    • Chan, E.F.1    Gat, U.2    McNiff, J.M.3    Fuchs, E.4
  • 19
    • 0030598681 scopus 로고    scopus 로고
    • Tgf-beta1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice
    • Cui W, Fowlis DJ, Bryson S, Duffie E, Ireland H, Balmain A, Akhurst RJ (1996) TGF-beta1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice. Cell 86:531-542
    • (1996) Cell , vol.86 , pp. 531-542
    • Cui, W.1    Fowlis, D.J.2    Bryson, S.3    Duffie, E.4    Ireland, H.5    Balmain, A.6    Akhurst, R.J.7
  • 21
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of bad couples survival signals to the cell-intrinsic death machinery
    • Datta SR, Dudek H, Tao X, Masters S, Fu H, Gotoh Y, Greenberg ME (1997) Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 91(2):231-241
    • (1997) Cell , vol.91 , Issue.2 , pp. 231-241
    • Datta, S.R.1    Dudek, H.2    Tao, X.3    Masters, S.4    Fu, H.5    Gotoh, Y.6    Greenberg, M.E.7
  • 22
    • 1842333237 scopus 로고    scopus 로고
    • Interleukin-3-induced phosphorylation of bad through the protein kinase akt
    • del Peso L, Gonzalez-Garcia M, Page C, Herrera R, Nunez G (1997) Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. Science 278(5338):687-689
    • (1997) Science , vol.278 , Issue.5338 , pp. 687-689
    • Del Peso, L.1    Gonzalez-Garcia, M.2    Page, C.3    Herrera, R.4    Nunez, G.5
  • 23
    • 0020616418 scopus 로고
    • Evidence that binding of 7,12-dimethylbenz(a)anthracene to dna in mouse embryo cell cultures results in extensive substitution of both adenine and guanine residues
    • Dipple A, Pigott M, Moschel RC, Costantino N (1983) Evidence that binding of 7,12-dimethylbenz(a)anthracene to DNA in mouse embryo cell cultures results in extensive substitution of both adenine and guanine residues. Cancer Res 43(9):4132-4135
    • (1983) Cancer Res , vol.43 , Issue.9 , pp. 4132-4135
    • Dipple, A.1    Pigott, M.2    Moschel, R.C.3    Costantino, N.4
  • 25
    • 0030802458 scopus 로고    scopus 로고
    • Induction of basal cell carcinoma features in transgenic human skin expressing sonic hedgehog
    • Fan H, Oro AE, Scott MP, Khavari PA (1997) Induction of basal cell carcinoma features in transgenic human skin expressing Sonic Hedgehog. Nat Med 3(7):788-792
    • (1997) Nat Med , vol.3 , Issue.7 , pp. 788-792
    • Fan, H.1    Oro, A.E.2    Scott, M.P.3    Khavari, P.A.4
  • 26
    • 0030461080 scopus 로고    scopus 로고
    • Quantitation of early clonal expansion of two mutant 61st codon c-ha-ras alleles in dmba/tpa treated mouse skin by nested pcr/rflp
    • Finch JS, Albino HE, Bowden GT (1996) Quantitation of early clonal expansion of two mutant 61st codon c-Ha-ras alleles in DMBA/TPA treated mouse skin by nested PCR/RFLP. Carcinogenesis 17(12):2551-2557
    • (1996) Carcinogenesis , vol.17 , Issue.12 , pp. 2551-2557
    • Finch, J.S.1    Albino, H.E.2    Bowden, G.T.3
  • 27
    • 84892680627 scopus 로고
    • The determining influence of tar, benzpyrene, and methylcholanthrene on the character of the benign tumors induced therewith in rabbit skin
    • Friedewald WF, Rous P (1944a) The determining influence of tar, benzpyrene, and methylcholanthrene on the character of the benign tumors induced therewith in rabbit skin. J Exp Med 80(2):127-144
    • (1944) J Exp Med , vol.80 , Issue.2 , pp. 127-144
    • Friedewald, W.F.1    Rous, P.2
  • 28
    • 85013554449 scopus 로고
    • The initiating and promoting elements in tumor production : An analysis of the effects of tar, benzpyrene, and methylcholanthrene on rabbit skin
    • Friedewald WF, Rous P (1944b) The initiating and promoting elements in tumor production : an analysis of the effects of tar, benzpyrene, and methylcholanthrene on rabbit skin. J Exp Med 80(2):101-126
    • (1944) J Exp Med , vol.80 , Issue.2 , pp. 101-126
    • Friedewald, W.F.1    Rous, P.2
  • 29
    • 0027272945 scopus 로고
    • Tumor promotion by inhibitors of protein phosphatases 1 and 2a: The okadaic acid class of compounds
    • Fujiki H, Suganuma M (1993) Tumor promotion by inhibitors of protein phosphatases 1 and 2A: the okadaic acid class of compounds. Adv Cancer Res 61:143-194
    • (1993) Adv Cancer Res , vol.61 , pp. 143-194
    • Fujiki, H.1    Suganuma, M.2
  • 30
    • 17144385531 scopus 로고    scopus 로고
    • Translational research on tnf-Alpha as an endogenous tumor promoter and green tea as cancer preventive in humans
    • Fujiki H, Suganuma M (2005) Translational research on TNF-Alpha as an endogenous tumor promoter and green tea as cancer preventive in humans. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev 23(1):3-30
    • (2005) J Environ Sci Health C Environ Carcinog Ecotoxicol Rev , vol.23 , Issue.1 , pp. 3-30
    • Fujiki, H.1    Suganuma, M.2
  • 31
    • 65249156519 scopus 로고    scopus 로고
    • Carcinogenic aspects of protein phosphatase 1 and 2a inhibitors
    • Fujiki H, Suganuma M (2009) Carcinogenic aspects of protein phosphatase 1 and 2A inhibitors. Prog Mol Subcell Biol 46:221-254
    • (2009) Prog Mol Subcell Biol , vol.46 , pp. 221-254
    • Fujiki, H.1    Suganuma, M.2
  • 32
    • 0028855586 scopus 로고
    • Malignant progression of papillomas induced by the initiation-promotion protocol in nmri mouse skin
    • Furstenberger G, Kopp-Schneider A (1995) Malignant progression of papillomas induced by the initiation-promotion protocol in NMRI mouse skin. Carcinogenesis 16(1):61-69
    • (1995) Carcinogenesis , vol.16 , Issue.1 , pp. 61-69
    • Furstenberger, G.1    Kopp-Schneider, A.2
  • 34
    • 0022343002 scopus 로고
    • Partial inversion of the initiation-promotion sequence of multistage tumorigenesis in the skin of nmri mice
    • Furstenberger G, Kinzel V, Schwarz M, Marks F (1985a) Partial inversion of the initiation-promotion sequence of multistage tumorigenesis in the skin of NMRI mice. Science 230(4721):76-78
    • (1985) Science , vol.230 , Issue.4721 , pp. 76-78
    • Furstenberger, G.1    Kinzel, V.2    Schwarz, M.3    Marks, F.4
  • 35
    • 0022006247 scopus 로고
    • Development of phorbol ester responsiveness in neonatal mouse epidermis: Correlation between hyperplastic response and sensitivity to first-stage tumor promotion
    • Furstenberger G, Schweizer J, Marks F (1985b) Development of phorbol ester responsiveness in neonatal mouse epidermis: correlation between hyperplastic response and sensitivity to first-stage tumor promotion. Carcinogenesis 6(2):289-294
    • (1985) Carcinogenesis , vol.6 , Issue.2 , pp. 289-294
    • Furstenberger, G.1    Schweizer, J.2    Marks, F.3
  • 37
    • 0032567078 scopus 로고    scopus 로고
    • De novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin
    • Gat U, DasGupta R, Degenstein L, Fuchs E (1998) De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin. Cell 95(5):605-614
    • (1998) Cell , vol.95 , Issue.5 , pp. 605-614
    • Gat, U.1    DasGupta, R.2    Degenstein, L.3    Fuchs, E.4
  • 38
    • 0035868759 scopus 로고    scopus 로고
    • Multiple classes of stem cells in cutaneous epithelium: A lineage analysis of adult mouse skin
    • Ghazizadeh S, Taichman LB (2001) Multiple classes of stem cells in cutaneous epithelium: a lineage analysis of adult mouse skin. EMBO J 20(6):1215-1222
    • (2001) EMBO J , vol.20 , Issue.6 , pp. 1215-1222
    • Ghazizadeh, S.1    Taichman, L.B.2
  • 39
    • 0018903399 scopus 로고
    • Positive twostage carcinogenesis in female sprague-dawley rats using 7,12-dimethylbenz(a)anthracene (dmba) as initiator and 12-o- Tetradecanoylphorbol-13-Acetate (tps) as promotor. Results of a pilot study
    • Goerttler K, Loehrke H, Schweizer J, Hesse B (1980a) Positive twostage carcinogenesis in female Sprague-Dawley rats using 7,12-dimethylbenz(a) anthracene (dmba) as initiator and 12-o-Tetradecanoylphorbol-13-Acetate (tps) as promotor. Results of a pilot study. Virchows Arch A Pathol Anat Histol 385(2):181-186
    • (1980) Virchows Arch A Pathol Anat Histol , vol.385 , Issue.2 , pp. 181-186
    • Goerttler, K.1    Loehrke, H.2    Schweizer, J.3    Hesse, B.4
  • 40
    • 0018898264 scopus 로고
    • Two-stage tumorigenesis of dermal melanocytes in the back skin of the syrian golden hamster using systemic initiation with 7,12-dimethylbenz(a) anthracene and topical promotion with 12-otetradecanoylphorbol-13-Acetate
    • Goerttler K, Loehrke H, Schweizer J, Hesse B (1980b) Two-stage tumorigenesis of dermal melanocytes in the back skin of the Syrian golden hamster using systemic initiation with 7,12-dimethylbenz(a)anthracene and topical promotion with 12-Otetradecanoylphorbol-13-Acetate. Cancer Res 40(1):155-161
    • (1980) Cancer Res , vol.40 , Issue.1 , pp. 155-161
    • Goerttler, K.1    Loehrke, H.2    Schweizer, J.3    Hesse, B.4
  • 41
    • 0021254052 scopus 로고
    • Skin tumor formation in the european hamster (cricetus cricetus L) after topical initiation with 7,12-dimethylbenz[a]anthracene (dmba) and promotion with 12-o-Tetradecanoylphorbol-13-Acetate tpa
    • Goerttler K, Loehrke H, Hesse B, Schweizer J (1984) Skin tumor formation in the European hamster (Cricetus cricetus L.) after topical initiation with 7,12-dimethylbenz[a]anthracene (DMBA) and promotion with 12-O- Tetradecanoylphorbol-13-Acetate (TPA). Carcinogenesis 5(4):521-524
    • (1984) Carcinogenesis , vol.5 , Issue.4 , pp. 521-524
    • Goerttler, K.1    Loehrke, H.2    Hesse, B.3    Schweizer, J.4
  • 45
    • 34347190534 scopus 로고
    • Ü ber die Wirkstoffe des Crotonöls
    • Hecker E (1963) Ü ber die Wirkstoffe des Crotonöls. Z Krebsforsch 65:325-333
    • (1963) Z Krebsforsch , vol.65 , pp. 325-333
    • Hecker, E.1
  • 46
    • 0019445897 scopus 로고
    • Cocarcinogenesis and tumor promoters of the diterpene ester type as possible carcinogenic risk factors
    • Hecker E (1981) Cocarcinogenesis and tumor promoters of the diterpene ester type as possible carcinogenic risk factors. J Cancer Res Clin Oncol 99(1-2):103-124
    • (1981) J Cancer Res Clin Oncol , vol.99 , Issue.1-2 , pp. 103-124
    • Hecker, E.1
  • 47
    • 0023062199 scopus 로고
    • Three stage carcinogenesis in mouse skin-recent results and present status of an advanced model system of chemical carcinogenesis
    • Hecker E (1987) Three stage carcinogenesis in mouse skin-recent results and present status of an advanced model system of chemical carcinogenesis. Toxicol Pathol 15(2):245-258
    • (1987) Toxicol Pathol , vol.15 , Issue.2 , pp. 245-258
    • Hecker, E.1
  • 49
    • 0027496668 scopus 로고
    • Fvb/n mice: An inbred strain sensitive to the chemical induction of squamous cell carcinomas in the skin
    • Hennings H, Glick AB, Lowry DT, Krsmanovic LS, Sly LM, Yuspa SH (1993) FVB/N mice: an inbred strain sensitive to the chemical induction of squamous cell carcinomas in the skin. Carcinogenesis 14(11):2353-2358
    • (1993) Carcinogenesis , vol.14 , Issue.11 , pp. 2353-2358
    • Hennings, H.1    Glick, A.B.2    Lowry, D.T.3    Krsmanovic, L.S.4    Sly, L.M.5    Yuspa, S.H.6
  • 50
    • 0019768451 scopus 로고
    • Irritant contact dermatitis in humans from phorbol and related esters
    • Hickey TA, Worobec SM, West DP, Kinghorn AD (1981) Irritant contact dermatitis in humans from phorbol and related esters. Toxicon 19(6):841-850
    • (1981) Toxicon , vol.19 , Issue.6 , pp. 841-850
    • Hickey, T.A.1    Worobec, S.M.2    West, D.P.3    Kinghorn, A.D.4
  • 51
    • 2842517040 scopus 로고
    • Tumor promoting effects of some long chain fatty acids in experimental skin carcinogenesis in the mouse
    • Holsti P (1959) Tumor promoting effects of some long chain fatty acids in experimental skin carcinogenesis in the mouse. Acta Pathol Microbiol Scand 46(1):51-58
    • (1959) Acta Pathol Microbiol Scand , vol.46 , Issue.1 , pp. 51-58
    • Holsti, P.1
  • 52
    • 0035907041 scopus 로고    scopus 로고
    • Beta-catenin controls hair follicle morphogenesis and stem cell differentiation in the skin
    • Huelsken J, Vogel R, Erdmann B, Cotsarelis G, Birchmeier W (2001) beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin. Cell 105(4):533-545
    • (2001) Cell , vol.105 , Issue.4 , pp. 533-545
    • Huelsken, J.1    Vogel, R.2    Erdmann, B.3    Cotsarelis, G.4    Birchmeier, W.5
  • 53
    • 0030933277 scopus 로고    scopus 로고
    • Oncoprotein networks
    • Hunter T (1997) Oncoprotein networks. Cell 88(3):333-346
    • (1997) Cell , vol.88 , Issue.3 , pp. 333-346
    • Hunter, T.1
  • 54
    • 0032126734 scopus 로고    scopus 로고
    • Transducing hedgehog: The story so far
    • Ingham PW (1998) Transducing Hedgehog: the story so far. EMBO J 17(13):3505-3511
    • (1998) EMBO J , vol.17 , Issue.13 , pp. 3505-3511
    • Ingham, P.W.1
  • 55
    • 28644451449 scopus 로고    scopus 로고
    • Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis
    • Ito M, Liu Y, Yang Z, Nguyen J, Liang F, Morris RJ, Cotsarelis G (2005) Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis. Nat Med 11(12):1351-1354
    • (2005) Nat Med , vol.11 , Issue.12 , pp. 1351-1354
    • Ito, M.1    Liu, Y.2    Yang, Z.3    Nguyen, J.4    Liang, F.5    Morris, R.J.6    Cotsarelis, G.7
  • 56
    • 0029902040 scopus 로고    scopus 로고
    • Inhibition of gap junctional intercellular communication and delocalization of the cell adhesion molecule e-cadherin by tumor promoters
    • Jansen LA, Mesnil M, Jongen WM (1996) Inhibition of gap junctional intercellular communication and delocalization of the cell adhesion molecule E-cadherin by tumor promoters. Carcinogenesis 17(7):1527-1531
    • (1996) Carcinogenesis , vol.17 , Issue.7 , pp. 1527-1531
    • Jansen, L.A.1    Mesnil, M.2    Jongen, W.M.3
  • 57
    • 0030895772 scopus 로고    scopus 로고
    • E-cadherin and p-cadherin have partially redundant roles in human epidermal stratification
    • Jensen PJ, Telegan B, Lavker RM, Wheelock MJ (1997) E-cadherin and P-cadherin have partially redundant roles in human epidermal stratification. Cell Tissue Res 288(2):307-316
    • (1997) Cell Tissue Res , vol.288 , Issue.2 , pp. 307-316
    • Jensen, P.J.1    Telegan, B.2    Lavker, R.M.3    Wheelock, M.J.4
  • 61
    • 1842335673 scopus 로고    scopus 로고
    • Patched (ptch)-Associated preferential expression of smoothened (smoh) in human basal cell carcinoma of the skin
    • Kallassy M, Toftgard R, Ueda M, Nakazawa K, Vorechovsky I, Yamasaki H, Nakazawa H (1997) Patched (ptch)-Associated preferential expression of smoothened (smoh) in human basal cell carcinoma of the skin. Cancer Res 57(21):4731-4735
    • (1997) Cancer Res , vol.57 , Issue.21 , pp. 4731-4735
    • Kallassy, M.1    Toftgard, R.2    Ueda, M.3    Nakazawa, K.4    Vorechovsky, I.5    Yamasaki, H.6    Nakazawa, H.7
  • 62
    • 0027203921 scopus 로고
    • Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors
    • Kemp CJ, Donehower LA, Bradley A, Balmain A (1993) Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors. Cell 74:813-822
    • (1993) Cell , vol.74 , pp. 813-822
    • Kemp, C.J.1    Donehower, L.A.2    Bradley, A.3    Balmain, A.4
  • 64
    • 0026723711 scopus 로고
    • Birth and death/differentiation rates of papillomas in mouse skin
    • Kopp-Schneider A, Portier CJ (1992) Birth and death/differentiation rates of papillomas in mouse skin. Carcinogenesis 13(6):973-978
    • (1992) Carcinogenesis , vol.13 , Issue.6 , pp. 973-978
    • Kopp-Schneider, A.1    Portier, C.J.2
  • 65
    • 0031022619 scopus 로고    scopus 로고
    • Sunlight and skin cancer: Another link revealed
    • Kraemer KH (1997) Sunlight and skin cancer: another link revealed. Proc Natl Acad Sci U S A 94(1):11-14
    • (1997) Proc Natl Acad Sci U S A , vol.94 , Issue.1 , pp. 11-14
    • Kraemer, K.H.1
  • 66
    • 0026480247 scopus 로고
    • Carcinogen-specific mutational pattern in the p53 gene in ultraviolet b radiation-induced squamous cell carcinomas of mouse skin
    • Kress S, Sutter C, Strickland PT, Mukhtar H, Schweizer J, Schwarz M (1992) Carcinogen-specific mutational pattern in the p53 gene in ultraviolet B radiation-induced squamous cell carcinomas of mouse skin. Cancer Res 52:6400-6403
    • (1992) Cancer Res , vol.52 , pp. 6400-6403
    • Kress, S.1    Sutter, C.2    Strickland, P.T.3    Mukhtar, H.4    Schweizer, J.5    Schwarz, M.6
  • 67
    • 0026567446 scopus 로고
    • Biology of cutaneous squamous cell carcinoma
    • Kwa RE, Campana K, Moy RL (1992) Biology of cutaneous squamous cell carcinoma. J Am Acad Dermatol 26(1):1-26
    • (1992) J Am Acad Dermatol , vol.26 , Issue.1 , pp. 1-26
    • Kwa, R.E.1    Campana, K.2    Moy, R.L.3
  • 70
    • 0037778008 scopus 로고    scopus 로고
    • The wnt signaling pathway and its role in tumor development
    • Lustig B, Behrens J (2003) The Wnt signaling pathway and its role in tumor development. J Cancer Res Clin Oncol 129(4):199-221
    • (2003) J Cancer Res Clin Oncol , vol.129 , Issue.4 , pp. 199-221
    • Lustig, B.1    Behrens, J.2
  • 71
    • 0030007249 scopus 로고    scopus 로고
    • Dose-Time response in mouse skin tumor induction by 7, 12-dimethylbenz[a]anthracene and 12-o-Tetradecanoyl-phorbol-13-Acetate
    • Lutz WK, Beland PE, Candrian R, Fekete T, Fischer WH (1996) Dose-Time response in mouse skin tumor induction by 7, 12-dimethylbenz[a]anthracene and 12-O-Tetradecanoyl-phorbol-13-Acetate. Regul Toxicol Pharmacol 23(1 Pt 1):44-48
    • (1996) Regul Toxicol Pharmacol , vol.23 , Issue.1 PART 1 , pp. 44-48
    • Lutz, W.K.1    Beland, P.E.2    Candrian, R.3    Fekete, T.4    Fischer, W.H.5
  • 73
    • 0037805547 scopus 로고    scopus 로고
    • Ras oncogenes: The first 30 years
    • Malumbres M, Barbacid M (2003) RAS oncogenes: the first 30 years. Nat Rev Cancer 3(6):459-465
    • (2003) Nat Rev Cancer , vol.3 , Issue.6 , pp. 459-465
    • Malumbres, M.1    Barbacid, M.2
  • 74
    • 0036190970 scopus 로고    scopus 로고
    • Role of glycogen synthase kinase-3 in cancer: Regulation by wnts and other signaling pathways
    • Manoukian AS, Woodgett JR (2002) Role of glycogen synthase kinase-3 in cancer: regulation by Wnts and other signaling pathways. Adv Cancer Res 84:203-229
    • (2002) Adv Cancer Res , vol.84 , pp. 203-229
    • Manoukian, A.S.1    Woodgett, J.R.2
  • 75
    • 0032478610 scopus 로고    scopus 로고
    • Requirement of ras-gtp-raf complexes for activation of raf-1 by protein kinase c
    • Marais R, Light Y, Mason C, Paterson H, Olson MF, Marshall CJ (1998) Requirement of Ras-GTP-Raf complexes for activation of Raf-1 by protein kinase C. Science 280(5360):109-112
    • (1998) Science , vol.280 , Issue.5360 , pp. 109-112
    • Marais, R.1    Light, Y.2    Mason, C.3    Paterson, H.4    Olson, M.F.5    Marshall, C.J.6
  • 76
    • 0025602534 scopus 로고
    • The conversion stage of skin carcinogenesis
    • Marks F, Furstenberger G (1990) The conversion stage of skin carcinogenesis. Carcinogenesis 11(12):2085-2092
    • (1990) Carcinogenesis , vol.11 , Issue.12 , pp. 2085-2092
    • Marks, F.1    Furstenberger, G.2
  • 77
    • 0242324604 scopus 로고
    • Promotion and cocarcinogenesis
    • In: Arcos JC, Argus MF, Woo YT (eds), Birkhäuser, Boston
    • Marks F, Schwarz M, Fürstenberger G (1995) Promotion and cocarcinogenesis. In: Arcos JC, Argus MF, Woo YT (eds) Chemical induction of cancer. Birkhäuser, Boston, pp 123-160
    • (1995) Chemical induction of cancer , pp. 123-160
    • Marks, F.1    Schwarz, M.2    Fürstenberger, G.3
  • 78
    • 0030884103 scopus 로고    scopus 로고
    • Pkb/akt: Connecting phosphoinositide 3-kinase to cell survival and beyond
    • Marte BM, Downward J (1997) PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond. Trends Biochem Sci 22(9):355-358
    • (1997) Trends Biochem Sci , vol.22 , Issue.9 , pp. 355-358
    • Marte, B.M.1    Downward, J.2
  • 82
    • 0020643399 scopus 로고
    • Model for human carcinogenesis: Action of environmental agents
    • Moolgavkar SH (1983) Model for human carcinogenesis: action of environmental agents. Environ Health Perspect 50:285-291
    • (1983) Environ Health Perspect , vol.50 , pp. 285-291
    • Moolgavkar, S.H.1
  • 83
    • 0346732296 scopus 로고    scopus 로고
    • The co-repressor hairless protects roralpha orphan nuclear receptor from proteasome-mediated degradation
    • Moraitis AN, Giguere V (2003) The co-repressor hairless protects RORalpha orphan nuclear receptor from proteasome-mediated degradation. J Biol Chem 278(52):52511-52518
    • (2003) J Biol Chem , vol.278 , Issue.52 , pp. 52511-52518
    • Moraitis, A.N.1    Giguere, V.2
  • 84
    • 0001449984 scopus 로고
    • A developing factor in experimental blastogenesis
    • Mottram JC (1944) A developing factor in experimental blastogenesis. J Pathol Bacteriol 56(2):181-187
    • (1944) J Pathol Bacteriol , vol.56 , Issue.2 , pp. 181-187
    • Mottram, J.C.1
  • 85
    • 33645988531 scopus 로고    scopus 로고
    • Inflammation in epithelial skin tumours: Old stories and new ideas
    • Mueller MM (2006) Inflammation in epithelial skin tumours: old stories and new ideas. Eur J Cancer 42(6):735-744
    • (2006) Eur J Cancer , vol.42 , Issue.6 , pp. 735-744
    • Mueller, M.M.1
  • 86
    • 0023764824 scopus 로고
    • The molecular heterogeneity of protein kinasecand its implications for cellular regulation
    • NishizukaY(1988) The molecular heterogeneity of protein kinaseCand its implications for cellular regulation. Nature 334(6184):661-665
    • (1988) Nature , vol.334 , Issue.6184 , pp. 661-665
    • Nishizuka, Y.1
  • 88
    • 0038819656 scopus 로고    scopus 로고
    • Contribution of stem cells and differentiated cells to epidermal tumours
    • Owens DM, Watt FM (2003) Contribution of stem cells and differentiated cells to epidermal tumours. Nat Rev Cancer 3(6): 444-451
    • (2003) Nat Rev Cancer , vol.3 , Issue.6 , pp. 444-451
    • Owens, D.M.1    Watt, F.M.2
  • 89
    • 44649160789 scopus 로고    scopus 로고
    • The vitamin d receptor is a wnt effector that controls hair follicle differentiation and specifies tumor type in adult epidermis
    • Palmer HG, Anjos-Afonso F, Carmeliet G, Takeda H, Watt FM (2008) The vitamin D receptor is a Wnt effector that controls hair follicle differentiation and specifies tumor type in adult epidermis. PLoS ONE 3(1):e1483
    • (2008) PLoS ONE , vol.3 , Issue.1
    • Palmer, H.G.1    Anjos-Afonso, F.2    Carmeliet, G.3    Takeda, H.4    Watt, F.M.5
  • 90
    • 0038819885 scopus 로고    scopus 로고
    • Stem-cell hierarchy in skin cancer
    • Perez-Losada J, Balmain A (2003) Stem-cell hierarchy in skin cancer. Nat Rev Cancer 3(6):434-443
    • (2003) Nat Rev Cancer , vol.3 , Issue.6 , pp. 434-443
    • Perez-Losada, J.1    Balmain, A.2
  • 91
    • 0020425524 scopus 로고
    • Tumour promotion by tcdd in skin of hrs/j hairless mice
    • Poland A, Palen D, Glover E (1982) Tumour promotion by TCDD in skin of HRS/J hairless mice. Nature 300:271-273
    • (1982) Nature , vol.300 , pp. 271-273
    • Poland, A.1    Palen, D.2    Glover, E.3
  • 92
    • 84989405753 scopus 로고
    • The epidermal proliferative unit: The possible role of the central basal cell
    • Potten CS (1974) The epidermal proliferative unit: the possible role of the central basal cell. Cell Tissue Kinet 7(1):77-88
    • (1974) Cell Tissue Kinet , vol.7 , Issue.1 , pp. 77-88
    • Potten, C.S.1
  • 93
    • 0035887252 scopus 로고    scopus 로고
    • The hairless gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor
    • Potter GB, Beaudoin GM 3rd, DeRenzo CL, Zarach JM, Chen SH, Thompson CC (2001) The hairless gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor. Genes Dev 15(20):2687-2701
    • (2001) Genes Dev , vol.15 , Issue.20 , pp. 2687-2701
    • Potter, G.B.1    Beaudoin III, G.M.2    DeRenzo, C.L.3    Zarach, J.M.4    Chen, S.H.5    Thompson, C.C.6
  • 94
    • 77949732073 scopus 로고    scopus 로고
    • Raf inhibitors transactivate raf dimers and erk signalling in cells with wild-Type braf
    • Poulikakos PI, Zhang C, Bollag G, Shokat KM, Rosen N (2010) RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-Type BRAF. Nature 464(7287):427-430
    • (2010) Nature , vol.464 , Issue.7287 , pp. 427-430
    • Poulikakos, P.I.1    Zhang, C.2    Bollag, G.3    Shokat, K.M.4    Rosen, N.5
  • 95
    • 0022527161 scopus 로고
    • Carcinogenspecific mutation and amplification of ha-ras during mouse skin carcinogenesis
    • Quintanilla M, Brown K, Ramsden M, Balmain A (1986) Carcinogenspecific mutation and amplification of Ha-ras during mouse skin carcinogenesis. Nature 322(6074):78-80
    • (1986) Nature , vol.322 , Issue.6074 , pp. 78-80
    • Quintanilla, M.1    Brown, K.2    Ramsden, M.3    Balmain, A.4
  • 97
    • 0023892768 scopus 로고
    • Differential effects of phorbol esters on c-fos and c-myc and ornithine decarboxylase gene expression in mouse skin in vivo
    • Rose-John S, Furstenberger G, Krieg P, Besemfelder E, Rincke G, Marks F (1988) Differential effects of phorbol esters on c-fos and c-myc and ornithine decarboxylase gene expression in mouse skin in vivo. Carcinogenesis 9(5):831-835
    • (1988) Carcinogenesis , vol.9 , Issue.5 , pp. 831-835
    • Rose-John, S.1    Furstenberger, G.2    Krieg, P.3    Besemfelder, E.4    Rincke, G.5    Marks, F.6
  • 98
    • 84970070866 scopus 로고
    • Conditional neoplasms and subthreshold neoplastic states : A study of the tar tumors of rabbits
    • Rous P, Kidd JG (1941) Conditional neoplasms and subthreshold neoplastic states : a study of the tar tumors of rabbits. J Exp Med 73(3):365-390
    • (1941) J Exp Med , vol.73 , Issue.3 , pp. 365-390
    • Rous, P.1    Kidd, J.G.2
  • 99
    • 0027500049 scopus 로고
    • Benzo[a]pyrene-induced murine skin tumors exhibit frequent and characteristic g to t mutations in the p53 gene
    • Ruggeri B, DiRado M, Zhang SY, Bauer B, Goodrow T, Klein-Szanto AJP (1993) Benzo[a]pyrene-induced murine skin tumors exhibit frequent and characteristic G to T mutations in the p53 gene. Proc Natl Acad Sci USA 90:1013-1017
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 1013-1017
    • Ruggeri, B.1    DiRado, M.2    Zhang, S.Y.3    Bauer, B.4    Goodrow, T.5    Klein-Szanto, A.J.P.6
  • 100
    • 79952253970 scopus 로고    scopus 로고
    • Molecular mechanisms of mouse skin tumor promotion
    • Rundhaug JE, Fischer SM (2010) Molecular mechanisms of mouse skin tumor promotion. Cancers (Basel) 2(2):436-482
    • (2010) Cancers Basel , vol.2 , Issue.2 , pp. 436-482
    • Rundhaug, J.E.1    Fischer, S.M.2
  • 101
    • 0032566307 scopus 로고    scopus 로고
    • Characterization of wnt gene expression in murine skin: Possible involvement of epidermis-derived wnt-4 in cutaneous epithelial-mesenchymal interactions
    • Saitoh A, Hansen LA, Vogel JC, Udey MC (1998) Characterization of Wnt gene expression in murine skin: possible involvement of epidermis-derived Wnt-4 in cutaneous epithelial-mesenchymal interactions. Exp Cell Res 243(1):150-160
    • (1998) Exp Cell Res , vol.243 , Issue.1 , pp. 150-160
    • Saitoh, A.1    Hansen, L.A.2    Vogel, J.C.3    Udey, M.C.4
  • 102
    • 0017670805 scopus 로고
    • Induction of the formation of new hair follicles in mouse tail epidermis by the tumor promoter 12-otetradecanoylphorbol-13-Acetate
    • Schweizer J, Marks F (1977) Induction of the formation of new hair follicles in mouse tail epidermis by the tumor promoter 12- Otetradecanoylphorbol-13-Acetate. Cancer Res 37(11):4195-4201
    • (1977) Cancer Res , vol.37 , Issue.11 , pp. 4195-4201
    • Schweizer, J.1    Marks, F.2
  • 103
    • 0030944985 scopus 로고    scopus 로고
    • Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16ink4a
    • Serrano M, Lin AW, McCurrach ME, Beach D, Lowe SW (1997) Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 88(5):593-602
    • (1997) Cell , vol.88 , Issue.5 , pp. 593-602
    • Serrano, M.1    Lin, A.W.2    McCurrach, M.E.3    Beach, D.4    Lowe, S.W.5
  • 104
    • 76549237272 scopus 로고
    • Studies on the promoting phase in the stages of carcinogenesis in mice, rats, rabbits, and guinea pigs
    • Shubik P (1950) Studies on the promoting phase in the stages of carcinogenesis in mice, rats, rabbits, and guinea pigs. Cancer Res 10(1):13-17
    • (1950) Cancer Res , vol.10 , Issue.1 , pp. 13-17
    • Shubik, P.1
  • 105
    • 0030239754 scopus 로고    scopus 로고
    • Is human patched the gatekeeper of common skin cancerš
    • Sidransky D (1996) Is human patched the gatekeeper of common skin cancerš Nat Genet 14(1):7-8
    • (1996) Nat Genet , vol.14 , Issue.1 , pp. 7-8
    • Sidransky, D.1
  • 106
    • 21344436821 scopus 로고    scopus 로고
    • Beta-catenin and hedgehog signal strength can specify number and location of hair follicles in adult epidermis without recruitment of bulge stem cells
    • Silva-Vargas V, Lo Celso C, Giangreco A, Ofstad T, Prowse DM, Braun KM, Watt FM (2005) Beta-catenin and Hedgehog signal strength can specify number and location of hair follicles in adult epidermis without recruitment of bulge stem cells. Dev Cell 9(1):121-131
    • (2005) Dev Cell , vol.9 , Issue.1 , pp. 121-131
    • Silva-Vargas, V.1    Lo Celso, C.2    Giangreco, A.3    Ofstad, T.4    Prowse, D.M.5    Braun, K.M.6    Watt, F.M.7
  • 107
    • 0019370196 scopus 로고
    • Hyperplasia of syrian hamster epidermis induced by single but not multiple treatments with 12-otetradecanoylphorbol-13-Acetate
    • Sisskin EE, Barrett JC (1981) Hyperplasia of Syrian hamster epidermis induced by single but not multiple treatments with 12-Otetradecanoylphorbol-13- Acetate. Cancer Res 41(1):346-350
    • (1981) Cancer Res , vol.41 , Issue.1 , pp. 346-350
    • Sisskin, E.E.1    Barrett, J.C.2
  • 108
    • 0022558843 scopus 로고
    • Sencar mouse skin tumorigenesis model versus other strains and stocks of mice
    • Slaga TJ (1986) SENCAR mouse skin tumorigenesis model versus other strains and stocks of mice. Environ Health Perspect 68:27-32
    • (1986) Environ Health Perspect , vol.68 , pp. 27-32
    • Slaga, T.J.1
  • 109
    • 0009506830 scopus 로고
    • Studies on the mechanism of skin tumor promotion: Evidence for several stages in promotion
    • Slaga TJ, Fischer SM, Nelson K, Gleason GL (1980) Studies on the mechanism of skin tumor promotion: evidence for several stages in promotion. Proc Natl Acad Sci U S A 77(6):3659-3663
    • (1980) Proc Natl Acad Sci U S A , vol.77 , Issue.6 , pp. 3659-3663
    • Slaga, T.J.1    Fischer, S.M.2    Nelson, K.3    Gleason, G.L.4
  • 111
    • 0031456672 scopus 로고    scopus 로고
    • Interaction of wnt and a frizzled homologue triggers g-protein-linked phosphatidylinositol signalling
    • Slusarski DC, Corces VG, Moon RT (1997) Interaction of Wnt and a Frizzled homologue triggers G-protein-linked phosphatidylinositol signalling. Nature 390(6658):410-413
    • (1997) Nature , vol.390 , Issue.6658 , pp. 410-413
    • Slusarski, D.C.1    Corces, V.G.2    Moon, R.T.3
  • 112
    • 0022289738 scopus 로고
    • Initiation and promotion in young and old animals. Implications for human tumour formation
    • Stenback F, Arranto A (1985) Initiation and promotion in young and old animals. Implications for human tumour formation. IARC Sci Publ 58:151-166
    • (1985) IARC Sci Publ , vol.58 , pp. 151-166
    • Stenback, F.1    Arranto, A.2
  • 114
    • 0030917227 scopus 로고    scopus 로고
    • The role of rhoa in tissue polarity and frizzled signalling
    • Strutt DI, Weber U, Mlodzik M (1997) The role of RhoA in tissue polarity and Frizzled signalling. Nature 387(6630):292-295
    • (1997) Nature , vol.387 , Issue.6630 , pp. 292-295
    • Strutt, D.I.1    Weber, U.2    Mlodzik, M.3
  • 120
    • 21644484717 scopus 로고    scopus 로고
    • Raf kinase inhibitory protein regulates raf-1 but not b-raf kinase activation
    • Trakul N, Menard RE, Schade GR, Qian Z, Rosner MR (2005) Raf kinase inhibitory protein regulates Raf-1 but not B-Raf kinase activation. J Biol Chem 280(26):24931-24940
    • (2005) J Biol Chem , vol.280 , Issue.26 , pp. 24931-24940
    • Trakul, N.1    Menard, R.E.2    Schade, G.R.3    Qian, Z.4    Rosner, M.R.5
  • 124
    • 0032577990 scopus 로고    scopus 로고
    • Epidermal stem cells: Markers, patterning and the control of stem cell fate
    • Watt FM (1998) Epidermal stem cells: markers, patterning and the control of stem cell fate. Philos Trans R Soc Lond B Biol Sci 353(1370):831-837
    • (1998) Philos Trans R Soc Lond B Biol Sci , vol.353 , Issue.1370 , pp. 831-837
    • Watt, F.M.1
  • 125
    • 0022142611 scopus 로고
    • Investigations of medicinal plants of euphorbiaceae and thymelaeaceae occurring and used in thailand; ii. Cryptic irritants of the diterpene ester type from three excoecaria species
    • Wiriyachitra P, Hajiwangoh H, Boonton P, Adolf W, Opferkuch HJ, Hecker E (1985) Investigations of medicinal plants of euphorbiaceae and thymelaeaceae occurring and used in Thailand; II. Cryptic irritants of the diterpene ester type from three Excoecaria species. Planta Med 5:368-371
    • (1985) Planta Med , vol.5 , pp. 368-371
    • Wiriyachitra, P.1    Hajiwangoh, H.2    Boonton, P.3    Adolf, W.4    Opferkuch, H.J.5    Hecker, E.6
  • 126
    • 4544286927 scopus 로고    scopus 로고
    • Strain-dependent differences in malignant conversion of mouse skin tumors is an inherent property of the epidermal keratinocyte
    • Woodworth CD, Michael E, Smith L, Vijayachandra K, Glick A, Hennings H, Yuspa SH (2004) Strain-dependent differences in malignant conversion of mouse skin tumors is an inherent property of the epidermal keratinocyte. Carcinogenesis 25(9): 1771-1778
    • (2004) Carcinogenesis , vol.25 , Issue.9 , pp. 1771-1778
    • Woodworth, C.D.1    Michael, E.2    Smith, L.3    Vijayachandra, K.4    Glick, A.5    Hennings, H.6    Yuspa, S.H.7
  • 128
    • 29344450418 scopus 로고    scopus 로고
    • Hairless suppresses vitamin d receptor transactivation in human keratinocytes
    • Xie Z, Chang S, Oda Y, Bikle DD (2006) Hairless suppresses vitamin D receptor transactivation in human keratinocytes. Endocrinology 147(1):314-323
    • (2006) Endocrinology , vol.147 , Issue.1 , pp. 314-323
    • Xie, Z.1    Chang, S.2    Oda, Y.3    Bikle, D.D.4
  • 130
    • 0022975853 scopus 로고
    • Cutaneous chemical carcinogenesis
    • Yuspa SH (1986) Cutaneous chemical carcinogenesis. J Am Acad Dermatol 15(5 Pt 1):1031-1044
    • (1986) J Am Acad Dermatol , vol.15 , Issue.5 PART 1 , pp. 1031-1044
    • Yuspa, S.H.1
  • 131
    • 0034746534 scopus 로고    scopus 로고
    • Dietary cancer risk from conditional cancerogens (tumor promoters) in produce of livestock fed on species of spurge (euphorbiaceae) V. Skin irriitant and tumor-promoting diterpene ester toxins of the tigliane and ingenane type in the herbs euphorbia nubica and euphorbia helioscopia contaminating fodder of livestock
    • Zayed SM, Farghaly M, Soliman SM, Gotta H, Sorg B, Hecker E (2001) Dietary cancer risk from conditional cancerogens (tumor promoters) in produce of livestock fed on species of spurge (Euphorbiaceae). V. Skin irriitant and tumor-promoting diterpene ester toxins of the tigliane and ingenane type in the herbs Euphorbia nubica and Euphorbia helioscopia contaminating fodder of livestock. J Cancer Res Clin Oncol 127(1):40-47
    • (2001) J Cancer Res Clin Oncol , vol.127 , Issue.1 , pp. 40-47
    • Zayed, S.M.1    Farghaly, M.2    Soliman, S.M.3    Gotta, H.4    Sorg, B.5    Hecker, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.