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Volumn 15, Issue 7, 2008, Pages 565-572

Integrated testing and intelligent assessment - New challenges under REACH

Author keywords

Chemicals; Ecotoxicity; In vitro testing; In vivo testing; Integrated assessment; Modes of action; QSAR; REACH; Read across; Regulation; Risk assessment; Testing strategies; Toxicity; Weight of evidence

Indexed keywords

BIOACCUMULATION; CHEMICAL SUBSTANCE; CONCENTRATION (COMPOSITION); ENDOCRINE DISRUPTOR; ENVIRONMENTAL LEGISLATION; ENVIRONMENTAL PROTECTION; EUROPEAN UNION; INTEGRATED APPROACH; LAW ENFORCEMENT; RISK ASSESSMENT; TESTING METHOD; TOXICITY;

EID: 55149115660     PISSN: 09441344     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11356-008-0043-y     Document Type: Conference Paper
Times cited : (57)

References (18)
  • 1
    • 33846142859 scopus 로고    scopus 로고
    • Acute to chronic ratios in aquatic toxicity-variation across trophic levels and relationship with chemical structure
    • J Ahlers C Riedhammer M Vogliano R-U Ebert R Kühne G Schüürmann 2006 Acute to chronic ratios in aquatic toxicity-variation across trophic levels and relationship with chemical structure Environ Toxicol Chem 25 2937 2945
    • (2006) Environ Toxicol Chem , vol.25 , pp. 2937-2945
    • Ahlers, J.1    Riedhammer, C.2    Vogliano, M.3    Ebert, R.-U.4    Kühne, R.5    Schüürmann, G.6
  • 5
    • 55149125249 scopus 로고
    • Council Regulation 793/93/EEC on the evaluation and control of risks of existing substances
    • EC
    • EC (1993) Council Regulation 793/93/EEC on the evaluation and control of risks of existing substances. Official Journal of the European Communities L161
    • (1993) Official Journal of the European Communities , vol.L161
  • 6
    • 84872771747 scopus 로고    scopus 로고
    • ECB (2008) Toxtree. http://ecb.jrc.it/qsar/qsar-tools/index.php?c=TOXTREE
    • (2008) Toxtree
  • 7
    • 55149086046 scopus 로고    scopus 로고
    • ECETOC. European Centre for Ecotoxicology and Toxicology of Chemicals Brussels Technical Report No. 97
    • ECETOC (2005) Alternative testing approaches in environmental safety assessment. European Centre for Ecotoxicology and Toxicology of Chemicals, Brussels Technical Report No. 97
    • (2005) Alternative Testing Approaches in Environmental Safety Assessment
  • 11
    • 33749630453 scopus 로고    scopus 로고
    • Nature of the binding interaction for 50 structurally diverse chemicals with rat estrogen receptors
    • SC Laws S Yavanhxay RL Cooper JC Eldridge 2006 Nature of the binding interaction for 50 structurally diverse chemicals with rat estrogen receptors Toxicol Sci 94 46 56
    • (2006) Toxicol Sci , vol.94 , pp. 46-56
    • Laws, S.C.1    Yavanhxay, S.2    Cooper, R.L.3    Eldridge, J.C.4
  • 14
    • 84872824646 scopus 로고    scopus 로고
    • OECD Structure-Activity Relationships Project.
    • OECD (2008) OECD Structure-Activity Relationships Project. http://www.oecd.org/document/23/0,3343,en_2649_34365_33957015_1_1_1_1,00.html
    • (2008)
  • 15
    • 33646473960 scopus 로고    scopus 로고
    • Prediction of estrogenicity: Validation of a classification model
    • 2
    • AG Saliner TI Netzeva AP Worth 2006 Prediction of estrogenicity: validation of a classification model SAR QSAR Environ Res 17 2 195 223
    • (2006) SAR QSAR Environ Res , vol.17 , pp. 195-223
    • Saliner, A.G.1    Netzeva, T.I.2    Worth, A.P.3
  • 16
    • 0346504195 scopus 로고    scopus 로고
    • Regulatory applications of SAR/QSAR for priority setting of endocrine disruptors: A perspective
    • 11-12
    • W Tong H Fang H Hong Q Xie R Perkins J Anson DM Sheehan 2003 Regulatory applications of SAR/QSAR for priority setting of endocrine disruptors: a perspective Pure Appl Chem 75 11-12 2375 2388
    • (2003) Pure Appl Chem , vol.75 , pp. 2375-2388
    • Tong, W.1    Fang, H.2    Hong, H.3    Xie, Q.4    Perkins, R.5    Anson, J.6    Sheehan, D.M.7
  • 17
    • 0026785215 scopus 로고
    • Classifying environmental pollutants. 1: Structure-activity relationships for prediction of aquatic toxicity
    • HJM Verhaar CJ Van Leeuwen JLM Hermens 1992 Classifying environmental pollutants. 1: structure-activity relationships for prediction of aquatic toxicity Chemosphere 25 471 491
    • (1992) Chemosphere , vol.25 , pp. 471-491
    • Verhaar, H.J.M.1    Van Leeuwen, C.J.2    Hermens, J.L.M.3
  • 18
    • 15344344378 scopus 로고    scopus 로고
    • Structural alerts-a new classification model to discriminate excess toxicity from narcotic effect levels of organic compounds in the acute Daphnid assay
    • PC Von der Ohe R Kühne R-U Ebert R Altenburger M Liess G Schüürmann 2005 Structural alerts-a new classification model to discriminate excess toxicity from narcotic effect levels of organic compounds in the acute Daphnid assay Chem Res Toxicol 18 536 555
    • (2005) Chem Res Toxicol , vol.18 , pp. 536-555
    • Von Der Ohe, P.C.1    Kühne, R.2    Ebert, R.-U.3    Altenburger, R.4    Liess, M.5    Schüürmann, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.