Exposure based waiving in environmental risk assessment: A tiered approach

Human and Ecological Risk Assessment

Volumn 17, Issue 6, 2011, Pages 1173-1192

  Hollander, Anne ^a   de Bruin, Yuri Bruinen ^b   Arie Vonk, J ^b   Vermeire, Theo ^b   van de Meent, Dik ^a,b  

^a RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^b NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

Author keywords

Dibutylphtalate; EBW; Exposure based waiving; Reach; Risk assessment

Indexed keywords

ANIMALIA;

EID: 84859454993     PISSN: 10807039     EISSN: 15497860     Source Type: Journal    
DOI: 10.1080/10807039.2011.618380     Document Type: Article

References (32)

1. Aldenberg T and Luttik R. 2002. Extrapolation factors for tiny toxicity data sets from species sensitivity distributions with known standard deviation. In: Posthuma L, Suter II GW, and Traas TP (eds), Species Sensitivity Distributions in Ecotoxicology, pp 103-18. Lewis Publishers, Boca Raton, FL, USA
2. Aldenberg T, Jaworska JS, and Traas TP. 2002. Normal sensitivity distributions and probabilistic ecological risk assessment. In: Pothuma L, Suter II GW, and Traas TP (eds), Species Sensitivity Distributions in Ecotoxicology, pp 49-102. Lewis Publishers, Boca Raton, FL, USA
3. Boethling RS, Howard PA, Beauman JA, et al. 1995. Factors for intermedia extrapolation in biodegradability assessment. Chemosphere 30:741-52
4. Brandes LJ, Den Hollander HA, and Van de Meent D. 1996. SimpleBox 2.0: A Nested Multimedia Fate Model for Evaluating the Environmental Fate of Chemicals. Report no. 719101029. National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands
5. Bruinen de Bruin Y, Koistinen K, Kephalopoulos S, et al. 2008. Characterisation of urban inhalation exposures to benzene, formaldehyde and acetaldehyde in the European Union-Comparison of measured and modelled exposure data. Environ Sci Pollut Res 15:417-30
6. Den Hollander H, Van Eijkeren JCH, and Van de Meent D. 2004. SimpleBox 3.0: Multimedia Mass Balance Model for Evaluating the Fate of Chemicals in the Environment. Report no. 601200003. National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands
7. De Wolf W, Siebel-Sauer A, Lecloux A, et al. 2005. Mode of action and aquatic exposure thresholds of no concern. Environ Tox Chem 24:479-85
8. De Zwart D. 2002. Observed regularities in species sensitivity distributions for aquatic species. In: Pothuma L, Suter II GW, and Traas TP (eds), Species Sensitivity Distributions in Ecotoxicology, pp 133-154. Lewis Publishers, Boca Raton, FL, USA
9. EC. 2007. Corrigendum to Regulation (EC) No. 1907/2006 of the European Parliament and of the Council of 18 December 2006 concerning the Registration, Evaluation, Authorization and Restriction of Chemicals (REACH), establishing a European Chemicals Agency, amending Directive 1999/45/EC and repealing Council Regulation (EEC) No 793/93 and Commission Regulation (EC) No. 1488/94 as well as Council Directive 76/769/EEC and Commission Directives 91/155/EEC, 93/67/EEC, 93/105/EC and 2000/21/EC. Off J Eur Union L 136 volume 50, 29 May 2007
10. ECETOC. 2009. The new and updated ECETOC Targeted Risk Assessment Tools. ECETOC, Brussels, Belgium. Available at http://www.ecetoc.org/tra
11. E-toxBase. 2010. Database for Ecotoxicity Data. National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands. Available at http://www.e-toxBase.eu
12. Fenner K, Scheringer M, MacLeod MJ, et al. 2005. Comparing estimates of persistence and long-range transport potential among multimedia models. Environ Sci Technol 39:1932-42
13. Gross M, Daginnus K, Deviller G, et al. 2009. Thresholds of toxicological concern for endocrine active substances in the aquatic environment. Integr Environ Assess Manage 6:2-11
14. Jager T, Rikken MGJ, and Van der Poel P. 1997. Uncertainty Analysis of EUSES: Improving Risk Assessment by Probabilistic Risk Assessment. Report no. 679102039. National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands
15. Jager T, Den Hollander HA, Van der Poel P, et al. 2001. Probabilistic environmental risk assessment for dibutylphtalate (DBP). Hum Ecol Risk Assess 7:1681-97
16. Kroes R, Galli C, Munro I, et al. 2000. Threshold of toxicological concern for chemical substances present in the diet: A practical tool for assessing the need for toxicity testing. Food Chem Toxicol 38:255-312
17. Kroes R, Kleiner J, and Renwick A. 2005. The threshold of toxicological concern concept in risk assessment. Toxicol Sci 86:226-30
18. Luttik R and Aldenberg T.1997. Extrapolation factors for small samples of pesticide toxicity data: Special focus on LD50 values for birds and mammals. Environ Toxicol Chem 16:1785-88
19. Mackay D. 1979. Finding fugacity feasible. Environ Sci Technol 13:1218-23
20. Mackay D and Paterson S. 1981. Calculating fugacity. Environ Sci Technol 15:1006-14
21. Mackay D, Paterson S, Cheung B, et al. 1985. Evaluation of the environmental behavior of chemicals with a level III fugacity model. Chemosphere 14:335-75
22. Meylan WM, Howard PH, Boethling RS, et al. 1999. Improved method for estimating bioconcentration/bioaccumulation factor from octanol/water partition coefficient. Environ Toxicol Chem 18:664-72
23. RAR. 2004. European Union Risk Assessment Report on Dibutyl phthalate. European Commission Joint Research Centre, EUR 19840 EN. European Chemicals Bureau-Existing Chemicals, Ispra, Italy. Available at http://ecb.jrc.it
24. REACH Guidance. 2008a. Guidance on Information Requirements and Chemical Safety Assessment Chapter R.5: Adaptation of Information Requirements. European Chemicals Agency (ECHA), Helsinki, Finland
25. REACH Guidance. 2008b. Guidance on Information Requirements and Chemical Safety Assessment Chapter R.7: Endpoint Specific Guidance. European Chemicals Agency (ECHA), Helsinki, Finland
26. REACH Guidance. 2008c. Guidance on Information Requirements and Chemical Safety Assessment Chapter R.10: Characterisation of Dose [Concentration]-Response for Environment. European Chemicals Agency (ECHA), Helsinki, Finland
27. Stroebe M, Scheringer M, and Hungerbuhler M. 2004. Measures of overall persistence and the temporal remote state. Environ Sci Technol 38:5665-73
28. Van Straalen NM. 2002. Theory of ecological risk assessment based on species sensitivity distributions. In: Pothuma L, Suter II GW, and Traas TP (eds), Species Sensitivity Distributions in Ecotoxicology, pp 37-48. Lewis Publishers, Boca Raton, FL, USA
29. Verhaar HJM, Van Leeuwen CJ, and Hermens JLM. 1992. Classifying environmental pollutants. Part1: Structure-activity relationships for prediction of aquatic toxicity. Chemosphere 25:471-91
30. Vermeire TG, Jager DT, Bussian B, et al. 1997. European Union system for the evaluation of substances (EUSES). Principles and structure. Chemosphere 34:1823-36
31. Vermeire T, Rikken M, Attias L, et al. 2005. European Union system for the evaluation of substances: The second version. Chemosphere 59:473-85
32. Vermeire T, Van de Bovenkamp M, Bruinen de Bruin Y, et al. 2010. Exposure based waiving under REACH. Regul Toxicol Pharm 58:408-20